Obstructive jaundice is caused by a blockage of the bile ducts that prevents bile from flowing from the liver to the small intestine. This blockage can be due to gallstones, pancreatic cancer, or other cancers. It causes jaundice (yellowing of the skin and eyes) as well as other symptoms like itching, abdominal pain, dark urine and pale stool. Diagnosis involves blood tests and imaging scans like ultrasound or MRI. Treatment depends on the underlying cause but may include antibiotics, ERCP, surgery, or transplantation if the liver is severely damaged.