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Obstructive jaundice
Patient identification
Name : FM
Gender : Female
Age : 54
Race : Malay
Marital status : Married
Address : Terengganu
Occupation : Librarian
History taken from patient
Date of admission : 20/9
Date of clerking : 21/9
Date of discharged : 23/9
History taking
Chief complaint
She is admitted due to vomiting food after
eating and epigastric pain with burning
sensation for one week.
History of Presenting Illness
She was apparently well until 1 week ago.
Epigastric pain
• Site – epigastric region
• Onset – Sunday
• Character – colicky, burning, pain on touching, no
awakening in night due to pain
• Radiation – no
• Alleviating factor – no
• Timing- after eating
• Exacerbating factor – no
• Pain score – 8/10
Associated symptoms
• Dyspepsia
• Tea colour urine
• Yellow discolouration of eyes
• Non pale stools
• No fever but feeling cold
• Loss of appetite
• Dizziness
Review of systems
• CNS – dizziness, long sightedness
• RS – no shortness of breath
• CVS – no chest pain
• US – no dysuria, incomplete bladder emptying
• MSK – no muscle weakness, bone pain
Past gynecological history
• Menarche at 13 years old
• Now already menopause at 47 years old
• Previously regular menses with regular period
(7 days)
Past medical history
• Hypertension – for 6 years, currently on
medication (atenolol)
• No diabetes mellitus
Past surgical history
• No surgery done before
• She was admitted to surgery ward in
September 2012 for acute cholecystitis. She is
discharged with antibiotics but need to follow
up under surgery clinic.
• She had back pain and now feeling well after
follow up with physiotherapist
Allergy history
• Allergic to penicillin
• no other food allergies
Drug history
• Currently on anti-hypertensive medication
• No taking any supplement or traditional
medicine
Family history
• Her mother is still alive
• Her father has Parkinson disease and passed
away
• Her mother has hypertension and diabetes
mellitus
• Her 5 children all are healthy
• No family history of malignancy
Social history
• No smoking
• No alcohol intake
GENERAL EXAMINATION
INSPECTION
On general inspection, a 54 years old Malay lady was lying comfortably in
supine position. She looked well, not in pain and not in respiratory distress.
The patient was alert and conscious regarding the place, time and person.
Hydrational status and nutritional status was clinically adequate. No any
gross deformity and abnormal involuntary movement found. There was a
cannula attach to her right dorsum of hand.
Vital sign:
Temperature(°C) : 37
Systolic blood pressure(mmHg) : 148
Diastolic Blood Pressure(mmHg) : 94
Pulse Rate (/min) : 65
Respiratory rate (/min) : 20
1. Upper limbs
a) Palms – moist, warm and pink in colour. No palmar erythema
b) Fingers and Nails – no peripheral cyanosis, no clubbing, no leuconychia, and
no koilonychia
c) Pulse rate -- 65 beats per minute with good volume and regular rhythm.
d) Respiratory rate was 20 breath/ min.
e) Forearm and arm – no scratch mark and bruises are found
f) Blood pressure – 148/94mmHg.
g) No flapping tremor present.
2. Head
a) Eyes- yellowish discolouration of sclera and conjuctiva was pink in
colour.
b) Mouth and tongue – moist , no any redness, no enlargement of
tonsil, no glossitis and no angular stomatitis. There was also no
central cyanosis. Uvula was centrally located
c) Oral hygiene was satisfied. There was no any discharge found at
both ears.
4. Chest wall and axilla
No spider naevi present.
5. Lower limbs
No pitting edema, posterior tibialis and dorsalis pedis pulse was felt.
3. Neck
There is no any enlargement of submental, submandibular, cervical and
supraclavicular lymph node.
Specific examination of the abdomen :
1. Inspection
 On inspection the abdomen was slightly distended and
symmetrical in shape.
 Abdomen move with respiration.
 The umblicus was centrally located and inverted.
 No any surgical scars,
 No prominent or dilated vein,
 No skin discolouration,
 No visible peristalsis,
 No visible pulsation.
 No coughing impulse present means that the orifice are
intact.
2. Palpation and percussion
On superficial palpation, there was tenderness at epigastric
region.
On deep palpation , there was no any palpable mass found.
Liver
The liver span was 9cm. Hepatomegaly was absent.
Spleen
Absent of splenomegaly. Troube space was resonance.
Murphy’s Sign
Absent
Left and right kidney
Not ballotable
Shifting dullnes
Negative
3. Auscultation
Bowel sound
Present of 4 bowel sound per minute
Renal bruits
Absent
The patient refused to undergo PR and external genitalia examination.
There is no enlargement of Virchow’s gland.
Provisional diagnosis
• Cholelithiasis
=Supporting points from history
-epigastric pain
-tea coloured urine
-yellow discolouration of sclera
-pain appears after having meal
-vomiting
=Supporting points from physical examination
-tenderness at epigastric region
Differential diagnosis
• Appendicitis
• Perforated peptic ulcer
• Acute pancreatitis
Investigation
• Laboratory
• Imaging
Laboratory
PROTHROMBIN TIME/ ACTIVATE PARTIALTHROMBOPLASTIN
CODE RESULT UNIT TYPE STATUS REFERENCE
RANGE
PT 11.3 SECOND 10.6 – 15.0
PTRatio 0.84
INR 0.79
APTT 72.7 SECOND HIGH 29.0 – 40.0
APTTRatio 2.2
LIVER FUNCTION TEST
CODE RESULT UNIT TYPE STATUS REFERENCE
RANGE
TOTAL
PROTEIN
77 g/L 66 - 83
ALBUMIN 44 g/L 35 - 52
GLOBUIN 33
A/G Ratio 1.3
ALP 125 U/L HIGH 30 - 120
ALT 348 U/L HIGH <45
TOTAL
BILIRUBIN
85.5 Umol/L HIGH 5.0 – 21.0
BLOOD UREA SERUM ELECTROLYTE CREATININE
CODE RESULT UNIT
TYPE
REFERENCE RANGE
UREA 3.3 mmol/L 2.8 – 7.2
SODIUM 135 mmol/L 133 - 145
POTASSIUM 3.7 mmol/L 3.3 – 5.1
CHLORIDE 104 mmol/L 96 - 108
CREATININE 58 umol/L 45 - 84
FULL BLOOD COUNT
CODE RESULT UNIT TYPE REFERENCE RANGE
WBC 7.5 10^9/L 4.5 – 11.0
NEUT 54.4 % 50.0 – 60.0
LYM 34.5 % 20.0 – 50.0
MONO 7.60 % 0.00 – 8.00
EOSI 2.70 % 0.00 – 4.00
BASO 0.800 % 0.500 – 1.000
RBC 4.91 10^12/L 4.00 – 5.00
HGB 144.0 g/L 120.0 – 160.0
PCV 0.431 L/L 0.390 – 0.450
MCV 87.8 fL 80.0 – 100.0
MCH 29.3 Pg 26.0 – 34.0
MCHC 334.0 g/L 310.0 – 370.0
RDW 13.2 %CV 11.6 – 14.8
PLT 236 10^9/L 150 - 400
Hepatitis B and C screening
- Non reactive
Ultrasound
• Liver is normal in echogenicity and echo
texture. Liver surface are smooth and focal
lesion seen. Gall bladder is not well distended
as patient is not fast. However multiple calculi
are seen within the gall bladder. Largest of
which measures 1.3 cm. Portal vein and
common bile duct are not dilated. No
intrahepatic biliary tree dilation. Visualized
pancreas is normal. Spleen is normal
measuring 8.4 cm. Conclusion : cholelithiasis
Management
21/9/13 She is given metronidazole,
azithromycin, paracetamol, vitamin K, atenolol.
23/9/13 (date of discharged) She is given
chlorpheniramine maleate and metronidazole
for 1 week course.

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jaundice

  • 2. Patient identification Name : FM Gender : Female Age : 54 Race : Malay Marital status : Married Address : Terengganu Occupation : Librarian History taken from patient Date of admission : 20/9 Date of clerking : 21/9 Date of discharged : 23/9
  • 3. History taking Chief complaint She is admitted due to vomiting food after eating and epigastric pain with burning sensation for one week.
  • 4. History of Presenting Illness She was apparently well until 1 week ago. Epigastric pain • Site – epigastric region • Onset – Sunday • Character – colicky, burning, pain on touching, no awakening in night due to pain • Radiation – no • Alleviating factor – no • Timing- after eating • Exacerbating factor – no • Pain score – 8/10
  • 5. Associated symptoms • Dyspepsia • Tea colour urine • Yellow discolouration of eyes • Non pale stools • No fever but feeling cold • Loss of appetite • Dizziness
  • 6. Review of systems • CNS – dizziness, long sightedness • RS – no shortness of breath • CVS – no chest pain • US – no dysuria, incomplete bladder emptying • MSK – no muscle weakness, bone pain
  • 7. Past gynecological history • Menarche at 13 years old • Now already menopause at 47 years old • Previously regular menses with regular period (7 days)
  • 8. Past medical history • Hypertension – for 6 years, currently on medication (atenolol) • No diabetes mellitus
  • 9. Past surgical history • No surgery done before • She was admitted to surgery ward in September 2012 for acute cholecystitis. She is discharged with antibiotics but need to follow up under surgery clinic. • She had back pain and now feeling well after follow up with physiotherapist
  • 10. Allergy history • Allergic to penicillin • no other food allergies
  • 11. Drug history • Currently on anti-hypertensive medication • No taking any supplement or traditional medicine
  • 12. Family history • Her mother is still alive • Her father has Parkinson disease and passed away • Her mother has hypertension and diabetes mellitus • Her 5 children all are healthy • No family history of malignancy
  • 13. Social history • No smoking • No alcohol intake
  • 14. GENERAL EXAMINATION INSPECTION On general inspection, a 54 years old Malay lady was lying comfortably in supine position. She looked well, not in pain and not in respiratory distress. The patient was alert and conscious regarding the place, time and person. Hydrational status and nutritional status was clinically adequate. No any gross deformity and abnormal involuntary movement found. There was a cannula attach to her right dorsum of hand. Vital sign: Temperature(°C) : 37 Systolic blood pressure(mmHg) : 148 Diastolic Blood Pressure(mmHg) : 94 Pulse Rate (/min) : 65 Respiratory rate (/min) : 20
  • 15. 1. Upper limbs a) Palms – moist, warm and pink in colour. No palmar erythema b) Fingers and Nails – no peripheral cyanosis, no clubbing, no leuconychia, and no koilonychia c) Pulse rate -- 65 beats per minute with good volume and regular rhythm. d) Respiratory rate was 20 breath/ min. e) Forearm and arm – no scratch mark and bruises are found f) Blood pressure – 148/94mmHg. g) No flapping tremor present. 2. Head a) Eyes- yellowish discolouration of sclera and conjuctiva was pink in colour. b) Mouth and tongue – moist , no any redness, no enlargement of tonsil, no glossitis and no angular stomatitis. There was also no central cyanosis. Uvula was centrally located c) Oral hygiene was satisfied. There was no any discharge found at both ears.
  • 16. 4. Chest wall and axilla No spider naevi present. 5. Lower limbs No pitting edema, posterior tibialis and dorsalis pedis pulse was felt. 3. Neck There is no any enlargement of submental, submandibular, cervical and supraclavicular lymph node.
  • 17. Specific examination of the abdomen : 1. Inspection  On inspection the abdomen was slightly distended and symmetrical in shape.  Abdomen move with respiration.  The umblicus was centrally located and inverted.  No any surgical scars,  No prominent or dilated vein,  No skin discolouration,  No visible peristalsis,  No visible pulsation.  No coughing impulse present means that the orifice are intact.
  • 18. 2. Palpation and percussion On superficial palpation, there was tenderness at epigastric region. On deep palpation , there was no any palpable mass found. Liver The liver span was 9cm. Hepatomegaly was absent. Spleen Absent of splenomegaly. Troube space was resonance. Murphy’s Sign Absent Left and right kidney Not ballotable Shifting dullnes Negative
  • 19. 3. Auscultation Bowel sound Present of 4 bowel sound per minute Renal bruits Absent The patient refused to undergo PR and external genitalia examination. There is no enlargement of Virchow’s gland.
  • 20. Provisional diagnosis • Cholelithiasis =Supporting points from history -epigastric pain -tea coloured urine -yellow discolouration of sclera -pain appears after having meal -vomiting =Supporting points from physical examination -tenderness at epigastric region
  • 21. Differential diagnosis • Appendicitis • Perforated peptic ulcer • Acute pancreatitis
  • 23. Laboratory PROTHROMBIN TIME/ ACTIVATE PARTIALTHROMBOPLASTIN CODE RESULT UNIT TYPE STATUS REFERENCE RANGE PT 11.3 SECOND 10.6 – 15.0 PTRatio 0.84 INR 0.79 APTT 72.7 SECOND HIGH 29.0 – 40.0 APTTRatio 2.2
  • 24. LIVER FUNCTION TEST CODE RESULT UNIT TYPE STATUS REFERENCE RANGE TOTAL PROTEIN 77 g/L 66 - 83 ALBUMIN 44 g/L 35 - 52 GLOBUIN 33 A/G Ratio 1.3 ALP 125 U/L HIGH 30 - 120 ALT 348 U/L HIGH <45 TOTAL BILIRUBIN 85.5 Umol/L HIGH 5.0 – 21.0
  • 25. BLOOD UREA SERUM ELECTROLYTE CREATININE CODE RESULT UNIT TYPE REFERENCE RANGE UREA 3.3 mmol/L 2.8 – 7.2 SODIUM 135 mmol/L 133 - 145 POTASSIUM 3.7 mmol/L 3.3 – 5.1 CHLORIDE 104 mmol/L 96 - 108 CREATININE 58 umol/L 45 - 84
  • 26. FULL BLOOD COUNT CODE RESULT UNIT TYPE REFERENCE RANGE WBC 7.5 10^9/L 4.5 – 11.0 NEUT 54.4 % 50.0 – 60.0 LYM 34.5 % 20.0 – 50.0 MONO 7.60 % 0.00 – 8.00 EOSI 2.70 % 0.00 – 4.00 BASO 0.800 % 0.500 – 1.000 RBC 4.91 10^12/L 4.00 – 5.00 HGB 144.0 g/L 120.0 – 160.0 PCV 0.431 L/L 0.390 – 0.450 MCV 87.8 fL 80.0 – 100.0 MCH 29.3 Pg 26.0 – 34.0 MCHC 334.0 g/L 310.0 – 370.0 RDW 13.2 %CV 11.6 – 14.8 PLT 236 10^9/L 150 - 400
  • 27. Hepatitis B and C screening - Non reactive
  • 28. Ultrasound • Liver is normal in echogenicity and echo texture. Liver surface are smooth and focal lesion seen. Gall bladder is not well distended as patient is not fast. However multiple calculi are seen within the gall bladder. Largest of which measures 1.3 cm. Portal vein and common bile duct are not dilated. No intrahepatic biliary tree dilation. Visualized pancreas is normal. Spleen is normal measuring 8.4 cm. Conclusion : cholelithiasis
  • 29. Management 21/9/13 She is given metronidazole, azithromycin, paracetamol, vitamin K, atenolol. 23/9/13 (date of discharged) She is given chlorpheniramine maleate and metronidazole for 1 week course.