This presentation discusses nuclear magnetic resonance spectroscopy (NMR), an analytical technique used to characterize organic molecules. It explains that NMR exploits the magnetic properties of atomic nuclei to determine physical and chemical properties of atoms and molecules. Two common types of NMR spectroscopy, 1H NMR and 13C NMR, are used to determine the types and numbers of hydrogen and carbon atoms in a molecule. The presentation also provides an overview of the principles of NMR, including how an external magnetic field causes nuclear spins to align and allows for energy transfer and emission of radiofrequency signals that produce the NMR spectrum. Finally, some applications of NMR are mentioned, such as distinguishing structural isomers and determining aromaticity or double bond character.

1. PRESENTATION ON:
NUCLEAR MAGNETIC RESONANCE
SPECTROSCOPY (NMR)
INTEGRAL UNIVERSITY,LUCKNOW
Session: 2016-2017
Presented by: Under the guidence of:
Mohd Muztaba
M.Pharm Mr. Paramdeep Bagga
Pharmacology

2. INTRODUCTION
 Nuclear magnetic resonance spectroscopy(NMR) is a powerful
analytical technique used to characterize organic molecules by
identifying carbon-hydrogen frameworks within molecules.
 It is a research technique that exploits the magnetic properties
of certain atomic nuclei.
 It determines the physical and chemical properties of atoms or
the molecules in which they are contained.

3. Types of NMR
• Two common types of NMR spectroscopy are used to
characterize organic structure:
– 1H NMR:- Used to determine the type and number of H
atoms in a molecule
– 13C NMR:- Used to determine the type of carbon atoms in
the molecule

4. • The theory behind NMR comes from the spin of
a nucleus and it generates a magnetic field.
• Without an external applied magnetic field, the
nuclear spins are random in directions.
• But when an external magnetic field (BO) is
present, the nuclei align themselves either with
or against the field of the external magnet.
Principles of NMR

5.  If an external magnetic field is applied, an energy
transfer (∆E) is possible between ground state to excited
state
 When the spin returns to its ground state level, the
absorbed radiofrequency energy is emitted at the same
frequency level.
 The emitted radiofrequency signal gives the NMR
spectrum of the concerned nucleus.

6. APPLICATION
 It is use to identification of structrul isomertism
eg. n-propanol ,isopropanol
 Identification of H bonding
 Use for determination of aromaticities of compound
 NMR technique use to distinguish betweeen cis and trans
isomer
 Detection of Electronegative atom
 Detection of some double bond character due to resonance

7. We hope you liked our presentation.
• Thank you! 