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Case 1- Dr Klein
• 45 yr woman
• Presents : Chest pain, fever
• PH: Lupus
4/25/2013

6/5/2013
4/25/13

6/05/13
Non Hodgkin’s lymphoma
Primary Pulmonary lymphoma
Non Hodgkin’s B cell lymphoma
• Primary pulmonary lymphoma develops as a
single tumor mass greater than 1 cm with or
without cavitations or bronchograms

• Increased risk of lymphoma with Lupus
• Increased risk of lymphoma with Cellcept
Case 2- Dr Kanne
• 79 yr old Ukrainian worked in textile factory
• Chronic cough, SOBOE
• Never smoker

• New Fever
Differential Diagnosis- Miliary nodules
• Granulomas- Sarcoidosis, Tuberculosis,
Histoplasmosis,
• Disseminiated Fungal disease
• Metastases
• Occupational lung diseases- Silicosis
SILICOSIS
Imaging findings
•
•
•
•
•
•

Multiple small rounded opacities 1-10 mm in size
Usually in upper lobes
May occasionally calcify centrally (20%)
Lymph node enlargement common
Eggshell calcification of hilar nodes (5%)
Cavitation may be a complication, with ischemic
necrosis or concomitant tuberculous infection
• Complicated Silicosis: Progressive massive fibrosis
Silicosis and Tuberculosis
(Silicotuberculosis)
• Individuals exposed to Silica: Much higher
incidence of TB
• Growth and spread of TB bacillus is increased
in silicosis
• TB bacillus multiplies faster and released
earlier from host cells
• Risk of TB in individuals with silicosis persists
for life.
• TB treatment for life
Case 3- Dr Yoo
• 79yr male
• Chronic cough
JAN 2012
May 2012

Jan 2013
JAN 2012

JAN2013
Diffuse Adenocarcinoma
• Zenker’s diverticulum
• History of aspiration
• Chronic cough

• Adenocarcinoma a mimic of pneumonia
• Diagnosis requires clinical discussion
Case 4 –Dr Ghoshadira
•
•
•
•
•
•

Young woman post Bilateral lung Transplant
Fever
Cough
Hypoxia,
Tachycardia, hypotension,
Admitted to MICU
VIBE post GAD
T1 DIR

T1 DIR FS

T2 DIR

SSFP

MDE

MDE-PSIR
Left atrial mass
Solitary, intracavitary, atrial mass
- Size of mass
- Origin of mass
- Lesion shape
- Lesion mobility
- Occurrence of prolapse
-MRI signal intensity
Aspergilloma
• Fungus ball: A tumor like granulomatous mass formed
by colonization of a fungus in a body cavity.

• In TX patients, airway colonization is a common
occurrence in such patients because of the exposure of
the transplanted lung to the environment and impaired
local host defenses, including mucociliary clearance.

• Hematogenous dissemination
Left Atrial Myxoma
Mass that arises from the interatrial septum from
a narrow base of attachment
• Myxomas tend to have markedly increased signal
intensity on T2-weighted MR images.
• Areas of decreased signal intensity due to the
presence of calcification or to magnetic
susceptibility artifacts caused by hemosiderin
• Contrast material enhancement is usually
heterogeneous, which also likely reflects the
presence of necrotic areas within the tumor but
intense enhancement may be seen
Myxoma and Thrombus
• Heterogeneous appearance and can
demonstrate variable signal intensity on spinecho images and low signal intensity on GRE
images.
• Gadolinium enhancement may be useful in
differentiating thrombus from myxoma, as the
thrombus will not enhance

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NERRS Oct 2013 Thoracic Radiology Case Answers

  • 1. Case 1- Dr Klein • 45 yr woman • Presents : Chest pain, fever • PH: Lupus
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  • 7. Primary Pulmonary lymphoma Non Hodgkin’s B cell lymphoma • Primary pulmonary lymphoma develops as a single tumor mass greater than 1 cm with or without cavitations or bronchograms • Increased risk of lymphoma with Lupus • Increased risk of lymphoma with Cellcept
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  • 9. Case 2- Dr Kanne • 79 yr old Ukrainian worked in textile factory • Chronic cough, SOBOE • Never smoker • New Fever
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  • 15. Differential Diagnosis- Miliary nodules • Granulomas- Sarcoidosis, Tuberculosis, Histoplasmosis, • Disseminiated Fungal disease • Metastases • Occupational lung diseases- Silicosis
  • 16. SILICOSIS Imaging findings • • • • • • Multiple small rounded opacities 1-10 mm in size Usually in upper lobes May occasionally calcify centrally (20%) Lymph node enlargement common Eggshell calcification of hilar nodes (5%) Cavitation may be a complication, with ischemic necrosis or concomitant tuberculous infection • Complicated Silicosis: Progressive massive fibrosis
  • 17. Silicosis and Tuberculosis (Silicotuberculosis) • Individuals exposed to Silica: Much higher incidence of TB • Growth and spread of TB bacillus is increased in silicosis • TB bacillus multiplies faster and released earlier from host cells • Risk of TB in individuals with silicosis persists for life. • TB treatment for life
  • 18.
  • 19. Case 3- Dr Yoo • 79yr male • Chronic cough
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  • 25. Diffuse Adenocarcinoma • Zenker’s diverticulum • History of aspiration • Chronic cough • Adenocarcinoma a mimic of pneumonia • Diagnosis requires clinical discussion
  • 26.
  • 27. Case 4 –Dr Ghoshadira • • • • • • Young woman post Bilateral lung Transplant Fever Cough Hypoxia, Tachycardia, hypotension, Admitted to MICU
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  • 30. T1 DIR T1 DIR FS T2 DIR SSFP MDE MDE-PSIR
  • 31. Left atrial mass Solitary, intracavitary, atrial mass - Size of mass - Origin of mass - Lesion shape - Lesion mobility - Occurrence of prolapse -MRI signal intensity
  • 32. Aspergilloma • Fungus ball: A tumor like granulomatous mass formed by colonization of a fungus in a body cavity. • In TX patients, airway colonization is a common occurrence in such patients because of the exposure of the transplanted lung to the environment and impaired local host defenses, including mucociliary clearance. • Hematogenous dissemination
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  • 34. Left Atrial Myxoma Mass that arises from the interatrial septum from a narrow base of attachment • Myxomas tend to have markedly increased signal intensity on T2-weighted MR images. • Areas of decreased signal intensity due to the presence of calcification or to magnetic susceptibility artifacts caused by hemosiderin • Contrast material enhancement is usually heterogeneous, which also likely reflects the presence of necrotic areas within the tumor but intense enhancement may be seen
  • 35. Myxoma and Thrombus • Heterogeneous appearance and can demonstrate variable signal intensity on spinecho images and low signal intensity on GRE images. • Gadolinium enhancement may be useful in differentiating thrombus from myxoma, as the thrombus will not enhance