NERRS Oct 2013 Thoracic Radiology Case Unknowns
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Case 1 describes a 45-year-old woman presenting with chest pain and fever who has a history of lupus. Case 2 involves a 79-year-old Ukrainian man who worked in a textile factory and presents with chronic cough, shortness of breath, and new fever. Case 3 is about a 79-year-old male with chronic cough. Case 4 is a young woman who received bilateral lung transplants and is now presenting with fever, cough, hypoxia, tachycardia, and hypotension.
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A 30-year-old male patient presented to the hospital with left lower abdominal pain, bloody diarrhea, and weight loss for the past three days. On examination, he had slight tenderness in the left iliac fossa. His symptoms, lab results, and colonoscopy findings were consistent with a diagnosis of ulcerative colitis. Ulcerative colitis is an autoimmune disease that causes inflammation of the colon's mucosal lining and is characterized by diarrhea, rectal bleeding, abdominal pain, and weight loss. Treatment involves medications like 5-aminosalicylic acid to reduce inflammation of the intestinal lining.
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Suprabha Pande has completed an online Introduction to Philosophy course offered by the University of Edinburgh. The course provided an introduction to major areas of contemporary philosophy including Epistemology, Philosophy of Science, Philosophy of Mind, Moral Philosophy and Metaphysics. The document acknowledges Suprabha Pande's completion of the online course but notes that it does not reflect the full curriculum available to students enrolled at the University of Edinburgh and does not confer a University of Edinburgh degree or credit.
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Nilanjan Bhattacharya completed an online course in Introduction to Philosophy from the University of Edinburgh on April 15, 2013. The course provided an introduction to major areas of philosophy research including Epistemology, Philosophy of Science, Philosophy of Mind, Moral Philosophy and Metaphysics. The course was taught by several professors from the School of Philosophy at the University of Edinburgh.
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This document assigns 4th year medical students to groups for their anaesthesiology posting from October 5-16, 2015. It lists the names of the students assigned to each of 8 groups, along with the supervising professors and doctors. The students will focus on: (1) dealing with death and dying patients (Groups 1 and 5); (2) dealing with brain dead patients and organ donation (Groups 2 and 6); (3) consent in anaesthesia (Groups 3 and 7); and (4) breaking bad news regarding anaesthesia complications (Groups 4 and 8). Students must submit a case report/reflective writing and log book to Pn Rojita by 5pm on October 16.
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Рентген флоуресценцийн багаж ба түүнийг орчин үеийн судалгаа шинжилгээнд ашиг...
“Лабораторийн шинжилгээний орчин үеийн багажууд ба түүний хэрэглээ” эрдэм шинжилгээний хуралд оюутны 2-р шатны шалгаруулалт ирүүлсэн бүтээл.
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Abstract Brain Tumor detection is challenging task in biomedical field. Image segmentation is a key step from the image processing to image analysis, it occupy an important place. The manual segmentation of brain image is challenging and time consuming task. An automated system overcomes the drawbacks as well as it segments the white matter, grey matter, cerebrospinal fluid and edema. This clustering approach is particularly used for brain tumor detection in abnormal MR images. In this paper the application of Modified FCM algorithm for Brain tumor detection and its classification by SVM algorithm is focused. The Magnetic Resonance image is converted in to vector format and that is given as input to the modified fuzzy c-means algorithm. In modified fuzzy c-means the steps are: initial fuzzy partitioning and fuzzy membership generation Cluster updation based on objective function, Assigning labels to pixels of each category and display segmented image that will give more meaningful regions to analyze. This clustered images served as inputs to SVM. The basic SVM takes a set of input data and predicts, for each given input, which of two possible classes. Keywords: Clustering, Classification, Fuzz C-Means, Support Vector Machine, MRI, Brain Tumor.
Рентген флоуресценцийн багаж ба түүнийг орчин үеийн судалгаа шинжилгээнд ашиг...
“Лабораторийн шинжилгээний орчин үеийн багажууд ба түүний хэрэглээ” эрдэм шинжилгээний хуралд оюутны 2-р шатны шалгаруулалт ирүүлсэн бүтээл.
Ц.Мөнхдэлгэр
Б.Хишигжаргал
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Nerrs neuro 2013 answers
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NERRS Abd Rad Answers 2012
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Рентген флоуресценцийн багаж ба түүнийг орчин үеийн судалгаа шинжилгээнд ашиг...
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NERRS February 2014 Emergency Radiology Case Unknowns
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This document discusses several unknown thoracic imaging cases presented by different physicians. It describes the patient histories and imaging findings of each case. The cases include a 51-year-old female with epithelioid hemangioendothelioma, a 71-year-old female who developed a tracheo-mediastinal fistula from previous tuberculosis, a 34-year-old woman with generalized cystic lymphangiomatosis, a 50-year-old female with diffuse panbronchiolitis, and a 35-year-old male found to have a rib osteochondroma on CT scan. Differential diagnoses and treatment options are discussed for each unknown case.
NERRS Abdominal Radiology Unknowns Sep 2012
This medical document describes 5 patients presenting with various gastrointestinal symptoms. A 29-year-old female reported left upper quadrant discomfort, a 43-year-old female had pelvic pain and rectal bleeding, and a 34-year-old female experienced recurrent right upper quadrant pain. Additionally, a 45-year-old man suffered from chronic low-grade fevers and right upper quadrant pain, and a 47-year-old female presented with abdominal pain and fever.
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NARCOTICS- POLICY AND PROCEDURES FOR ITS USE
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Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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DECLARATION OF HELSINKI - History and principles
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Skin Diseases That Happen During Summer.
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Top Travel Vaccinations in Manchester
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The Nervous and Chemical Regulation of Respiration
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
How to Control Your Asthma Tips by gokuldas hospital.
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis is an increasing cause of morbidity among the elderly.
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CLEAR ALIGNER THERAPY IN ORTHODONTICS .pptx
Dr. ZANAB FARHEEN FAYAZ ,MDS(ORTHODONTICS & DENTOFACIAL ORTHOPEDICS ).
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
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10 Benefits an EPCR Software should Bring to EMS Organizations
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How to Control Your Asthma Tips by gokuldas hospital.
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NERRS Oct 2013 Thoracic Radiology Case Unknowns
- 1. Case 1- Dr Klein • 45 yr woman • Presents : Chest pain, fever • PH: Lupus
- 7. Case 2- Dr Kanne • 79 yr old Ukrainian worked in textile factory • Chronic cough, SOBOE • Never smoker • New Fever
- 13. Case 3- Dr Yoo • 79yr male • Chronic cough
- 14. JAN 2012
- 18. JAN 2012 JAN2013
- 19. Case 4 –Dr Ghoshadira • • • • • • Young woman post Bilateral lung Transplant Fever Cough Hypoxia, Tachycardia, hypotension, Admitted to MICU
- 21. VIBE post GAD
- 22. T1 DIR T1 DIR FS T2 DIR SSFP MDE MDE-PSIR