This document describes a method for obtaining cellulose nanofibers with a uniform width of 15 nm from wood. Key steps include solvent extraction, removal of lignin and hemicellulose, grinding the purified cellulose into a slurry, and keeping the nanofibers in a water-swollen state to prevent hydrogen bonding between bundles. SEM images showed continuous nanofibers forming a fine network without thicker fibrils. Nanocomposites made with the fibers demonstrated high light transmittance and a low coefficient of thermal expansion, indicating their reinforcing properties. The method provides a way to produce environmentally friendly natural nanomaterials on a nano scale.
20180323 electrospinning and polymer nanofibersTianyu Liu
The slides for a guest lecture of a graduate course (Chem 6564) offered by the Department of Chemistry, Virginia Polytechnic Institute and State University.
Content
■ History of Nanofibers.
■ What is Nanofibers
■ Properties of Nanofibers
■ Production of Nanofibers
■ Advantage and Disadvantage of Nanofibers
■ Application of nanofibers
Nanofiber Technology & different techniques. Eliminating the use of solvent MEK. Suitable solvents with different Techniques to produce nanofiber coatings. Applications of nanofiber technology. Market analysis and startup project team build up for the same.
It is described about polymer/clay nanocomposites which can be abbreviated to PCNC, their preparation methods, properties and relevances, important types of polymers employed in the preparation of PCNC, montmorillonite crystal structures,
20180323 electrospinning and polymer nanofibersTianyu Liu
The slides for a guest lecture of a graduate course (Chem 6564) offered by the Department of Chemistry, Virginia Polytechnic Institute and State University.
Content
■ History of Nanofibers.
■ What is Nanofibers
■ Properties of Nanofibers
■ Production of Nanofibers
■ Advantage and Disadvantage of Nanofibers
■ Application of nanofibers
Nanofiber Technology & different techniques. Eliminating the use of solvent MEK. Suitable solvents with different Techniques to produce nanofiber coatings. Applications of nanofiber technology. Market analysis and startup project team build up for the same.
It is described about polymer/clay nanocomposites which can be abbreviated to PCNC, their preparation methods, properties and relevances, important types of polymers employed in the preparation of PCNC, montmorillonite crystal structures,
This presentation slide is prepared by myself. Information is collected from books, google and other relevant sources. All right reserved my author. Thanks.
The use of nanotechnology in the textile industry has increased rapidly due to its unique and valuable properties. The recent development of nanotechnology in textile areas including textile formation and textile finishing basically based on nanoparticles. Nanoparticles may consist of various elements and compounds and have a length of 1 to 100 nm. Nanoparticles are the most important elements which are now widely used to develop the textile materials and introduce new properties in textiles products.
Tonal Innovation Center (TONIC) hosted the second annual International Musical Instruments Seminar in Joensuu, Finland on 14th September- 16th September 2011.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
2. Nanofibers
Nanofibers are defined as fibers with a diameter below
100 nm.
Cellulose Nanofibers
• Cellulose Nanofiber is made from wood-derived fiber (pulp) that
has been micro-refined to the nano level of several hundredths of a
micron and smaller.
• Cellulose nanofiber is the world's most advanced biomass
material.
3. Characteristics of Cellulose Nanofibers
• Light and strong
• Ultra-fine fibers
• Very large surface-to volume ratio and the formation of
a highly porous mesh
• High Young’s modulus (138 GPa in the crystal region
along the longitudinal direction)
• Very low coefficient of thermal expansion
• The composites are optically transparent due to their
diameters being less than one-tenth of the visible light
wavelength.
• High gas barrier properties
• Environmentally-friendly biomass material
4. • In cell walls, cellulose nanofibers are embedded in matrix
substances such as hemicellulose and lignin.
• In cell walls, cellulose microfibril bundles 12-16 nm in width
exist encased by the embedding matrix.
Wood powder from Radiata pine sieved under 60 mesh was
used for this study. Then:
1. Solvent extraction was performed in a Soxhlet
apparatus with a 2:1 mixture of toluene/ethanol for 6 h.
2. Lignin in the sample was removed using an acidified
sodium chlorite solution at 70 °C for an hour, and the
process was repeated until the product became white.
Preparation of Cellulose Nanofibers
5. 3. The sample was treated in 6 wt % potassium hydroxide over night
at room temperature and then at the same concentration at 80 °C for
2 h in order to leach hemicelluloses.
4. Slurry of 1 wt % purified cellulose through a grinder at 1500 rpm.
5. The cellulose nanofibers kept the material in the water-swollen
state after the removal of the matrix.
Preparation of Cellulose Nanofibers (cont’d)
6. • The drying process in typical
pulp production generates strong
hydrogen bonding between the
bundles after the removal of the
matrix.
• which seems to make it difficult
to obtain thin and uniform
cellulose nanofibers.
Reason for Keeping Cellulose Nanofibers in Wet Condition
7. Properties of Cellulose Nanofibers
The nanofibers shows a remarkably high viscosity, suggesting that
the homogeneous dispersion of hydrophilic cellulose nanofibers
with a high surface-to-volume ratio in water was accomplished.
8. (a) the freeze-dried and (b,c) oven-dried 0.2 wt % slurry.
SEM Images Observation
All images show continuous nanofibers with a uniform diameter of
approximately 15 nm, forming a very fine network. A remarkable outcome of
this new nanofiber extraction method can be seen in Figure 2c. Thicker fibrils
were not observed anywhere within the extensive area of 2 µm×2.5 µm.
9. Light Transmittance of Nanocomposites
To substantiate the uniformity and fineness of the nanofibers, we
produced nanocomposites with acrylic resin using the nanofiber as a
filler.
• The regular transmittance of this nanocomposite is higher
than that of the BC nanocomposite in the visible wavelength
range and at the same thickness and filler content.
10. • The coefficient of thermal expansion from 20 to 150 °C
was as low as 13 ppm/K.
• It is one-seventh of that of the neat acrylic resin.
• It suggests that the fine network of the nanofibers with
a high aspect ratio contributes to its high reinforcing
efficiency.
Coefficient of Thermal Expansion
12. Reference
Abe, K., Iwamoto, S., & Yano, H. (2007). Obtaining
cellulose nanofibers with a uniform width of 15 nm
from wood. Biomacromolecules, 8(10), 3276-3278.