Presentation by Dr. Linda Nagel to introduce the Adaptive Silviculture for Climate Change (ASCC) project at the Northern Rockies ASCC Workshop held June 28, 2016
Dr. Linda Nagel presents specific concepts and tools to inform management of natural resources under climate change, and to incorporate adaptation strategies into silvicultural decision-making, at the Adaptive Silviculture for Climate Change (ASCC) Workshop for the Northern Rockies.
Linh Hoang, USDA Forest Service Region 1 Climate Change Coordinator, presents the 2012 Planning Rule and how practical applications are needed to translate climate information into climate-informed management, at the Adaptive Silviculture for Climate Change (ASCC) Workshop for the Northern Rockies.
Presentation by Linda Nagel to introduce the Adaptive Silviculture for Climate Change (ASCC) J.W. Jones Ecological Research Center Workshop held January 12-14, 2016
Presentation by Linda Nagel to introduce the Adaptive Silviculture for Climate Change (ASCC) J.W. Jones Ecological Research Center Workshop held January 12-14, 2016
Dr. Linda Nagel presents specific concepts and tools to inform management of natural resources under climate change, and to incorporate adaptation strategies into silvicultural decision-making, at the Adaptive Silviculture for Climate Change (ASCC) Workshop for the Northern Rockies.
Linh Hoang, USDA Forest Service Region 1 Climate Change Coordinator, presents the 2012 Planning Rule and how practical applications are needed to translate climate information into climate-informed management, at the Adaptive Silviculture for Climate Change (ASCC) Workshop for the Northern Rockies.
Presentation by Linda Nagel to introduce the Adaptive Silviculture for Climate Change (ASCC) J.W. Jones Ecological Research Center Workshop held January 12-14, 2016
Presentation by Linda Nagel to introduce the Adaptive Silviculture for Climate Change (ASCC) J.W. Jones Ecological Research Center Workshop held January 12-14, 2016
Presentation given by Maria Janowiak to the the Hudson to Housatonic (H2H) Conservation Initiative for the H2H Conservation in a Changing Climate workshop on December 11, 2014.
Presentation about the draft Adaptation Resource for Agriculture that have been developed by the USDA Regional Climate Hubs: Midwest, Northeast, and Northern Forests.
Tracking change in land use and vegetation conditionRichard Thackway
Seminar 'Tracking change in land use and vegetation condition' presented to the Department of Agriculture, Fisheries and Forestry, Canberra on 22 February 2013.
Issues and Solutions for SFM in a Changing Climate in the AP regionCIFOR-ICRAF
This presentation was delivered at the third Asia-Pacific Forestry Week 2016, in Clark Freeport Zone, Philippines.
The five sub-thematic streams at APFW 2016 included:
Pathways to prosperity: Future trade and markets
Tackling climate change: challenges and opportunities
Serving society: forestry and people
New institutions, new governance
Our green future: green investment and growing our natural assets
Selecting and applying modelling tools to evaluate forest management strategi...CIFOR-ICRAF
This presentation was delivered at the third Asia-Pacific Forestry Week 2016, in Clark Freeport Zone, Philippines.
The five sub-thematic streams at APFW 2016 included:
Pathways to prosperity: Future trade and markets
Tackling climate change: challenges and opportunities
Serving society: forestry and people
New institutions, new governance
Our green future: green investment and growing our natural assets
Forests and Climate Change: New Approaches for Adaptation and Carbon ManagementMaria Janowiak
Forestry and natural resource professionals are increasingly looking for information on the anticipated effects of climate change on ecosystems, as well as potential management options for responding to these changes. At the same time, the inability to know exactly what will happen in the future can create significant barriers for incorporating new information into management planning and project implementation. The Climate Change Response Framework (www.forestadaptation.org), has developed a structured approach that enables managers to integrate climate change considerations into real-world management activities. This approach, which includes the Adaptation Workbook, assists managers in creating management plans, projects, and prescriptions that enhance the ability of forests and other ecosystems to adapt, while simultaneously working to achieve the management goals associated with a particular piece of land.
The Adaptation Workbook has been used by hundreds of natural resource professionals to generate site-specific adaptation actions that meet explicit management and conservation objectives. To date, more than 200 adaptation demonstration projects have been developed on public, tribal, and private lands. This presentation will provide an overview of the Adaptation Workbook and other resources that have been developed through the Framework and describe adaptation efforts that are underway. This network of projects allows us to see concerns, barriers, and opportunities common across many projects and identify characteristics of adaptation projects that are well-poised to increase the ability to adapt to future conditions. Additionally, new resources are in development that extend this approach beyond traditional forest management to new topics, including urban forestry, management of forested watershed and water resources, and carbon management.
Thresholds of Climate Change in EcosystemsAndy Dabydeen
CCSP, 2009: Thresholds of Climate Change in Ecosystems. A report by the U.S. Climate Change Science Program and the Subcommittee on Global Change Research. [ Fagre D.B., Charles C.W., Allen C.D., Birkeland C., Chapin F.S. III, Groffman P.M., Guntenspergen G.R., Knapp A.K., McGuire A.D., Mulholland P.J., Peters D.P.C., Roby D.D., and Sugihara G.] U.S. Geological Survey, Departement of the Interior, Washington D.C., USA.
This presentation was delivered at the third Asia-Pacific Forestry Week 2016, in Clark Freeport Zone, Philippines.
The five sub-thematic streams at APFW 2016 included:
Pathways to prosperity: Future trade and markets
Tackling climate change: challenges and opportunities
Serving society: forestry and people
New institutions, new governance
Our green future: green investment and growing our natural assets
Objectives
- Develop an approach to identify the land-surface changes due to wildfires
- Detect land-surface property changes for multiple mega-fires in the U.S.
- Develop a scheme to parameterize the changes
Melissa Jenkins, Forest Silviculturist for the Flathead National Forest, provides an overview of the ecological dynamics and typical silviculture of northern Rocky Mountains forest types, at the Adaptive Silviculture for Climate Change (ASCC) Workshop.
Presentation given by Maria Janowiak to the the Hudson to Housatonic (H2H) Conservation Initiative for the H2H Conservation in a Changing Climate workshop on December 11, 2014.
Presentation about the draft Adaptation Resource for Agriculture that have been developed by the USDA Regional Climate Hubs: Midwest, Northeast, and Northern Forests.
Tracking change in land use and vegetation conditionRichard Thackway
Seminar 'Tracking change in land use and vegetation condition' presented to the Department of Agriculture, Fisheries and Forestry, Canberra on 22 February 2013.
Issues and Solutions for SFM in a Changing Climate in the AP regionCIFOR-ICRAF
This presentation was delivered at the third Asia-Pacific Forestry Week 2016, in Clark Freeport Zone, Philippines.
The five sub-thematic streams at APFW 2016 included:
Pathways to prosperity: Future trade and markets
Tackling climate change: challenges and opportunities
Serving society: forestry and people
New institutions, new governance
Our green future: green investment and growing our natural assets
Selecting and applying modelling tools to evaluate forest management strategi...CIFOR-ICRAF
This presentation was delivered at the third Asia-Pacific Forestry Week 2016, in Clark Freeport Zone, Philippines.
The five sub-thematic streams at APFW 2016 included:
Pathways to prosperity: Future trade and markets
Tackling climate change: challenges and opportunities
Serving society: forestry and people
New institutions, new governance
Our green future: green investment and growing our natural assets
Forests and Climate Change: New Approaches for Adaptation and Carbon ManagementMaria Janowiak
Forestry and natural resource professionals are increasingly looking for information on the anticipated effects of climate change on ecosystems, as well as potential management options for responding to these changes. At the same time, the inability to know exactly what will happen in the future can create significant barriers for incorporating new information into management planning and project implementation. The Climate Change Response Framework (www.forestadaptation.org), has developed a structured approach that enables managers to integrate climate change considerations into real-world management activities. This approach, which includes the Adaptation Workbook, assists managers in creating management plans, projects, and prescriptions that enhance the ability of forests and other ecosystems to adapt, while simultaneously working to achieve the management goals associated with a particular piece of land.
The Adaptation Workbook has been used by hundreds of natural resource professionals to generate site-specific adaptation actions that meet explicit management and conservation objectives. To date, more than 200 adaptation demonstration projects have been developed on public, tribal, and private lands. This presentation will provide an overview of the Adaptation Workbook and other resources that have been developed through the Framework and describe adaptation efforts that are underway. This network of projects allows us to see concerns, barriers, and opportunities common across many projects and identify characteristics of adaptation projects that are well-poised to increase the ability to adapt to future conditions. Additionally, new resources are in development that extend this approach beyond traditional forest management to new topics, including urban forestry, management of forested watershed and water resources, and carbon management.
Thresholds of Climate Change in EcosystemsAndy Dabydeen
CCSP, 2009: Thresholds of Climate Change in Ecosystems. A report by the U.S. Climate Change Science Program and the Subcommittee on Global Change Research. [ Fagre D.B., Charles C.W., Allen C.D., Birkeland C., Chapin F.S. III, Groffman P.M., Guntenspergen G.R., Knapp A.K., McGuire A.D., Mulholland P.J., Peters D.P.C., Roby D.D., and Sugihara G.] U.S. Geological Survey, Departement of the Interior, Washington D.C., USA.
This presentation was delivered at the third Asia-Pacific Forestry Week 2016, in Clark Freeport Zone, Philippines.
The five sub-thematic streams at APFW 2016 included:
Pathways to prosperity: Future trade and markets
Tackling climate change: challenges and opportunities
Serving society: forestry and people
New institutions, new governance
Our green future: green investment and growing our natural assets
Objectives
- Develop an approach to identify the land-surface changes due to wildfires
- Detect land-surface property changes for multiple mega-fires in the U.S.
- Develop a scheme to parameterize the changes
Melissa Jenkins, Forest Silviculturist for the Flathead National Forest, provides an overview of the ecological dynamics and typical silviculture of northern Rocky Mountains forest types, at the Adaptive Silviculture for Climate Change (ASCC) Workshop.
Dr. Robert Keane of RMRS Missoula Fire Lab and contributor to the Northern Rockies Adaptation Partnership assessment, presents climate change impacts and vulnerabilities for forests of the northern Rockies at the Adaptive Silviculture for Climate Change (ASCC) Workshop.
Dr. Jessica Halofsky, co-author on the Northern Rockies Adaptation Partnership climate assessment, covers observed and projected climate trends for the northern Rocky Mountains region, including temperature, precipitation, and hydrology changes at the Adaptive Silviculture for Climate Change (ASCC) Workshop.
Silviculture for Smallholders: improving local forestry value chainsCIFOR-ICRAF
This presentation by James Roshetko from ICRAF given during the Forests Asia Summit in the discussion forum "Equitable development: Improving livelihood benefits for smallholders in the forestry value chain" focuses on understanding farmer systems and farmer silviculture. It shows the Farmer demo trials and recommendations as well.
Silviculture and management of ash: best practice advice for woodland manager...Edward Wilson
This presentation was prepared for the Living Ash Project Chalara Ash Dieback Workshop at Lawshall, Suffolk on 18 June 2014.
The talk aims to provide an overview of the silviculture and management of ash woodlands in Britain, where Chalara ash dieback is currently a major threat. The lecture starts with an overview of the key drivers in forestry at the present time, including the need to adapt and enhance the ecological resilience of woodlands in the face of many threats (climate change, pests, diseases). A major theme is the need to diversify the range of genotypes, species and structures of woodlands so that the risk of major damage is minimised. A large number of silvicultural practices are reviewed, and several, including planting alternative species and continuous cover forestry, are presented in more detail.
With respect to ash, a number of silvicultural and management measures have been introduced to slow the rate of infection, minimise environmental impacts and realise the value of ash timber. Practical guidance is provided, based on information from the Forestry Commission and Royal Forestry Society. In addition, there is greater need for monitoring forest conditions so that infected trees can be located as quickly as possible.
Finally, the presentation highlights the role of research and the need to identify ash trees that demonstrate a degree of tolerance or resistance to infection. These trees are an important priority for the Living Ash Project and for future ash tree breeding programmes.
The presentation includes many photographs taken in the field and supplied with acknowledgement by colleagues.
Further information on the Living Ash Project is available at www.livingashproject.org.uk. Also at the Future Trees Trust, www.futuretrees.org. General information about the biology and management of Chalara ash dieback is available from the Forestry Commission, www.forestry.gov.uk/chalara.
Operationalizing Safety II Using Participatory Action ResearchSpringboard Labs
How do you make a breakthrough in chronic workplace injuries across the silviculture sector in British Columbia? This presentation presents the results of a participatory action research conducted in 2102 that used a resilient systems approach to discover the system of factors affecting worker injuries for Worksafe British Columbia.
This is a presentation given in a wildland fire session at the 9th World Wilderness Congress held in Merida, Mexico, 9 November 2009. It gives an overview of fire management in several Latin America countries.
Integrating Climate Change and Forest AdaptationMaria Janowiak
Presentation to University of Maine Climate Change Institute, April 2018.
Abstract: More and more information is becoming available about how forests and other
ecosystems may change in response to a warmer and changing climate, but it can be
challenging to integrate this information into real-world management plans and
activities. This seminar will discuss adaptation as a growing field of science and
applications of adaptation approaches, highlighting the USDA Climate Adaptation
Workbook (adaptationworkbook.org/), with on-the-ground examples like the Adaptive
Silviculture for Climate Change (forestadaptation.org/ascc) national experiment.
Chris Swanston gave this invited presentation at the 2017 Environmental Justice in the Anthropocene Symposium.
The Forest Service recognizes that climate change poses a multi-generational challenge that spans borders, transcends unilateral solutions, and demands shared learning and resources (USDA Forest Service 2011). The Climate Change Response Framework (CCRF, www.forestadaptation.org) grew from this recognition, and was formally launched in 2009 to address the major challenges that land managers face when considering how to integrate climate change into their planning and management. Practitioners whose livelihoods and communities depend on healthy forests face daunting challenges when responding to rapid forest decline or preparing for future change, particularly tribal natural resources professionals and tribal communities (Vogesser et al. 2013). Emphasizing climate services support for these rural communities can help them build adaptive capacity in their cultural and economic systems, often considered fundamental to environmental justice. Supporting climate-informed decision-making by these practitioners and communities requires climate service organizations to show up, listen, and then creatively work with practitioners to meet their own goals on the lands they manage. The emphasis of the CCRF on stewardship goals, as opposed to climate change and its effects, represents a subtle but important shift in focus to people and their values.
Presentation by Maria Janowiak of the Northern Institute of Applied Climate Science at the New England Society of American Foresters 2015 Winter Meeting.
Danielle Shannon (Michigan Technological University and NIACS), presented at the Adapting Forested Watersheds to Climate Change Workshop, at Antioch University New England, Keene, NH on April 4-5, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and Trout Unlimited.
Details at www.forestadaptation.org/water
Danielle Shannon (Michigan Technological University and NIACS), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Details at www.forestadaptation.org/water
State Action Plan June 2013 Briefing, Doug Beard, USGS National Climate Change and Wildlife. Department of Interior Climate Science Centers and National Climate Change and Wildlife Science Center
- Explore how crop and forest management influences decadal scale climate predictions
- Improve the representation of managed ecosystems in Earth system models
- Specific focus on institutional strengths: soil carbon dynamics, pine plantation forestry, plant physiology under warming temperatures, forest nitrogen cycling
- Evaluate and reduce uncertainty associated with ecological processes in climate predictions
Land Trust Alliance Rally, November 2017.
Land trust activities are constantly changing to accommodate new challenges and issues, and it’s becoming increasingly important to develop and implement conservation activities that consider the challenges of a changing and uncertain climate. This fast-paced, dynamic workshop will lead participants through a five-step process to consider how climate change will affect their lands and conservation goals. This “climate change filter” will then be used to identify actions that enable forest ecosystems to adapt to changing conditions. The session will also identify strategies to engage woodland owner networks in these important stewardship activities, including climate change communication to key audiences and stakeholders.
Presentation from the 2015 Connecticut Land Conservation Conference by Maria Janowiak. Climate change creates substantial uncertainty about the future, but it is certain that there will be substantial effects on natural ecosystems. This session will help to begin a discussion of how climate change information can be integrated
into conservation activities in Connecticut, with an emphasis on terrestrial ecosystems and land management.
Through a workshop with land trusts and conservation organizations, we discussed key climate change impacts and ways to enhance the ability of ecosystems to cope with changing conditions.
Handout created by the Northern Institute of Applied Climate Science, Vermont Coverts, and Vermont Department of Forest, Parks, and Recreation for woodland owners in Vermont.
The Keep Forests Healthy scorecard can help you assess how resilient your forest may be to changing climate conditions. Consider the condition of your woods and check the appropriate boxes during a woods walk in your forest. The evaluation can help you identify potential risks and highlight management options that may increase the forest's ability to cope with the pressure of changing conditions. Discuss these topics with a professional as you plan for the future of your forest.
Handout created by the Northern Institute of Applied Climate Science, the Forest Climate Change Initiative at the University of Maine, and the Forest Stewards Guild for woodland owners in Maine
Climate change is altering forest ecosystems, with many changes expected by the end of the 21st century. Forests vary widely, and not all forests are equally at risk; vulnerabilities are strongly influenced by regional differences in climate impacts and adaptive capacity. Further, as an increasing amount of scientific information on forest vulnerability to climate change becomes available, natural resource managers are searching for ways to realistically use this information to meet specific management needs, ranging from landscape-level planning and coordination to on-the-ground implementation.
Forest Ecology and Management Webinar Series - August 13, 2019
Workshop at UConn in June 2018.
Foresters and natural resource professionals face a tremendous challenge: how can we develop and implement management actions that help ecosystems respond to climate change? New England Forestry Foundation (NEFF) and partners are dedicated to the sustainability of our region’s forested landscape and are providing this workshop to help foresters learn more about climate-informed silviculture.
This session:
Reviewed current and anticipated effects of climate change on Connecticut’s forests;
Described resources and tools that can be used to integrate climate change into forest management practices;
Offered communication strategies to help landowners and clients understand the importance of this type of management;
Showed real-world examples of adaptation actions.
Overview of Climate Change Adaptation Concepts presented at the 2018 Michigan Wetlands Association "Adapting Wetlands to Climate Change" workshop, hosted by NIACS.
Presentation by Kyle Jones, Marsh-Billings-Rockefeller National Historical Park, at the New England Society of American Forester's 2017 Annual Winter Meeting.
Wesley Daniel (of Michigan State University), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI). Details at www.forestadaptation.org/water.
Randy Lehr (Northland College), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Dale Higgins (Forest Service), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Dennis Todey (of USDA ARS and USDA Midwest Climate Hub), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Joseph Shannon (of Michigan Technological University), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Andrew Rypel (of Wisconsin Department of Natural Resources), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Stephen Handler (Forest Service, and NIACS), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
Dean Paron (of Minnesota Department of Natural Resources), presented at the Adapting Forested Watersheds to Climate Change Workshop, at The Waters, Minocqua, WI on March 15-16, 2017. The workshop was hosted by the Northern Institute of Applied Climate Science (NIACS), USDA Climate Hubs, and the Wisconsin Initiative on Climate Change Impacts (WICCI).
More from Northern Institute of Applied Climate Science (20)
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...
Nagel - Adaptive Silviculture for Climate Change Intro
1. ADAPTIVE SILVICULTURE FOR CLIMATE CHANGE
WORKSHOP
SRS / NRS / RMRS
Chippewa NF
San Juan NF
Flathead NF
Flathead National Forest
June 28, 2016
Linda Nagel, Professor & Department Head
Forest & Rangeland Stewardship
Colorado State University
2. Workshop Goals
To introduce natural resource
managers to conceptual tools and
approaches that help integrate
climate change into natural
resource management and
silvicultural decision making
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3. Today’s Agenda
8:00-8:30 Welcome and overview (Nagel)
8:30-9:15 Climate science overview (Swanston)
9:30-10:00 Climate change for the Northern Rockies
(Halofsky)
10:00-10:30 CC considerations (Nagel)
10:45-11:15 Ecology & silviculture of Northern Rockies
forests (Jenkins)
11:15-12:00 CC impact & vulnerabilities (Keane)
12:00-1:00 Lunch
1:00-1:45 CC in the Forest Service, big-picture (Hoang)
1:45-2:15 Adaptation (Nagel)
2:30-4:45 Group activity: Developing adaptation
approaches and tactics (Nagel & Roske)
5:00 Wrap-up, adjourn
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4. Forest managers need robust, operational examples of how to
integrate climate change adaptation into silvicultural planning
and on-the-ground actions that can…
• Foster resilience to the impacts of climate change and/or
• Enable adaptation to uncertain futures
Original Core Team:
• Linda Nagel – Lead University PI, CSU, NIACS
• Jim Guldin – Lead Forest Service PI, SRS
• Matt Powers – ASCC Project Coordinator, OSU, NIACS
• Chris Swanston – Research Ecologist & Director of NIACS, NRS
• Maria Janowiak – Deputy Director, NRS, NIACS
AdaptiveSilviculture for Climate Change (ASCC)
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5. SRS: Jim Guldin (PI)
NRS/NIACS:
Chris Swanston
Maria Janowiak
NRS: Brian Palik
RMRS: Linda Joyce
PSW: Connie Millar
PNW: Dave
Peterson
OSU: Lisa Ganio
PI: Linda Nagel, CSU
SITE 2: San Juan NF
Collaborators
Study SitesSITE 1: Cutfoot EF
on Chippewa NF
SITE 5: Hubbard Brook
EF & Second College
Grant (Dartmouth)
SITE 4: Coram
EF on Flathead
NF
SITE 3: Jones Ecological Ctr
Site Lead: Steve Jack
Adaptive Silviculture for Climate Change (ASCC)
PIs
Mike Battaglia
3/27/16
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6. AdaptiveSilviculture for Climate Change (ASCC)
PROJECT GOALS (1)
Populate a multi-region study design with ecosystem-
specific climate change adaptation treatments using
input from an expert panel of regional scientists and
local managers
• Primary objectives: compare key variables among 4 adaptation
treatments in 3-5 different forest types across the United States
• Forest growth and productivity
• Overstory and understory species composition
• Forest health and/or tree vigor
Treatments
Resistance
Resilience
Transition
No Action
Sensu Millar et al 2007
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7. AdaptiveSilviculture for Climate Change (ASCC)
PROJECT GOALS (2)
Introduce natural resource managers to conceptual
tools and approaches that help integrate climate
change into natural resource management and
silvicultural decision making
• Primary objectives: conduct training sessions at participating Forests
for an audience of local managers and scientists
• Discuss projected climate change impacts and vulnerabilities relevant to
local management goals
• Introduce conceptual tools that help managers identify appropriate
adaptation approaches and tactics
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