This document defines acute myocardial infarction (AMI or heart attack) and discusses its causes, risk factors, signs and symptoms, diagnostic testing, treatment options, and long-term management. An AMI occurs when blood flow to the heart is reduced, damaging heart muscle. The main causes are blockages in the coronary arteries, often due to blood clots forming on top of plaques. Risk factors include age, family history, smoking, diabetes, high blood pressure, high cholesterol, obesity, and physical inactivity. Treatment focuses on restoring blood flow through medications, angioplasty, or bypass surgery, along with long-term lifestyle changes and medications to prevent future issues.