The male genital system includes both internal and external structures. The external genitalia are the penis and scrotum. The internal genitalia include the testes, epididymis, vas deferens, seminal vesicles, prostate, and urethra. The penis has three erectile tissues (corpora cavernosa and corpus spongiosum) and is covered in skin. The urethra pierces through the penis. The testes produce sperm and testosterone. During ejaculation, seminal fluid is secreted by the seminal vesicles and prostate to transport sperm through the urethra. Common clinical issues involving the male genital structures include inflammation, infections, tumors and congenital anomalies.
anatomy of stomach,functions of stomach, location, shape position and parts of stomach,orifices of stomach, curvature of stomach, relations of stomach, blood supply, innervation, lymphatic drainage, clinical relation , GERD, peptic ulcer,
anatomy of stomach,functions of stomach, location, shape position and parts of stomach,orifices of stomach, curvature of stomach, relations of stomach, blood supply, innervation, lymphatic drainage, clinical relation , GERD, peptic ulcer,
Anatomy of urinary bladder. surfaces, border of urinary bladder its relation , ligament support, peritoneal relation in male and females, pouches, blood supply of bladder, nerve supply of bladder, true and false ligament of urinary bladder,
location, length, and relation of right an left ureter, raletion of male an female ureter, n physiological site of ureteric constriction, bloo supply an inerve supply of ureter, clinical sinificance of ureter with hysteriectpomy
anatomy of duodenum, location or position of duodenum, parts of duodenum, relations of each parts of duodenum, ligaments of treitz, visceral and peritoneal relation of duodenum, blood supply of duodenum, innervation of duodenum, clinical aspects of duodenum, duodenal ulcer, diverticulum, deodinitis, duodenal obstruction
Describe the structures, relations, and functions of the adrenal gland.
describe the histological structures and clinical importance of the adrenal gland
Anatomy of urinary bladder. surfaces, border of urinary bladder its relation , ligament support, peritoneal relation in male and females, pouches, blood supply of bladder, nerve supply of bladder, true and false ligament of urinary bladder,
location, length, and relation of right an left ureter, raletion of male an female ureter, n physiological site of ureteric constriction, bloo supply an inerve supply of ureter, clinical sinificance of ureter with hysteriectpomy
anatomy of duodenum, location or position of duodenum, parts of duodenum, relations of each parts of duodenum, ligaments of treitz, visceral and peritoneal relation of duodenum, blood supply of duodenum, innervation of duodenum, clinical aspects of duodenum, duodenal ulcer, diverticulum, deodinitis, duodenal obstruction
Describe the structures, relations, and functions of the adrenal gland.
describe the histological structures and clinical importance of the adrenal gland
the material discuss about a medical condition that has to deal with sexual development. in different stages of development, there is a need for gender identity and role, if there is a problem with any of these 2, there will be a problem with the sex assignment which will have an effect on the external genitalia sex. if all these pathway fall apart, there will be a condition called hermaphroditism which may be true or false. the material is exclusive on the topic
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
5. Bulb – attached to perineal membrane in b/n
crura – covered by bulbospongiosus.
Pierced by urethra.
Body:
Completely enveloped by skin.
Composed of 3 elongated masses of erectile
tissue – 2 ‘corpora cavernosa’ (continuation of
crura) and a median ‘corpus spongiosum’
(contin. Of bulb).
Terminal part of c.spongiosum expanded –
‘glans penis’.
6. Rim like raised surface at its proximal end –
‘corona glandis’.
Circular groove, ‘coronal sulcus’ runs along
corona glandis and seperates it from the
shaft of penis – k/a ‘neck’ of the penis.
At the neck, the skin covering the penis is
folded to form the ‘prepuce’ or ‘foreskin’ –
retracted backwards to expose the glans.
Space b/n glans and prepuce – ‘preputial sac’.
7.
8. prepuce is attached to
the glans at its ventral
surface – ‘frenulum’.
On the corona and
neck of the penis –
numerous small
preputial or sebaceous
glands – secrete
smegma – collected in
the sac.
10. Applied anatomy:Applied anatomy:
1. PPP – Small pin head sized
projections studded over corona
in one r two rows.
confused with condyloma
acuminata.
2. Preputial sac – due to
occlusive effect over the glans –
vulnerable for inflammation-
‘balanoposthitis’.
3. Tight frenulum – predisposes
to trauma during sexual
intercourse – serves as another
11. Scrotum:Scrotum:
Cutaneous fibromuscular sac, which contains
testes, epididymis, vas deferens and loose
areolar tissue.
Layers: (o i)
Skin
Dartos muscle – is prolonged into a median
vertical septum b/n the 2 halves of the
scrotum.
External spermatic fascia.
Cremasteric muscle and fascia.
12. Internal spermatic fascia.
Divided into right and left halves by a
cutaneous raphe – indicates b/l origin of the
scrotum from the genital swellings.
Left side of the scrotum is usually lower
because the left spermatic cord is longer.
13.
14. Skin – thin, pigmented and rugous.
Has hairs, sebaceous glands (charac. Odor)
and also sweat glands, pigment cells and
nerve endings.
No subcutaneous adipose tissue.
Drained into superficial inguinal nodes.
15. Applied anatomy:
Abundance of hair and sebaceous glands –
site of sebaceous cysts.
Vulnerablility to genital ulcer ds. Due to
proximity with penis.
Ulcers over penoscrotal junction and
scrotum are seen in behcet’s ds.
Phthirus pubis (pubic louse) enjoys the
habitat of scrotal and pubic hair.
S.skin can be predisposed to develop nodular
scabies and persistent pruritic nodules of
scabies.
16.
17. Male urethra:Male urethra:
long membranous canal for discharging
urine and seminal fluid.
extends from bladder neck to external
urinary meatus.
divided into:
Prostatic post.
Membranous urethra
spongy or penile --- ant. Urethra.
18.
19. Prostatic urethra:
Tunnels through the subs. of prostate.
3-4 cms is length
Lined by transitional epithelium
Widest and most dilatable part of male
urethra.
Post. Wall has a midline ridge called as
‘urethral crest’.
On each side of crest – shallow depression
called ‘prostatic sinus’ – perforated by orifices
of 15-20 prostatic ducts.
20.
21. Elevation in the middle
of urethral crest –
‘verumontanum’ (a/k
colliculus seminalis) –
contains slit like orifice
of prostatic utricle.
Openings of
ejaculatory ducts are
present on either side
of this orifice.
22. Membranous urethra:
1.5 cms – shortest, least dilatable.
Part which passes through the perineal
membrane.
Lined by transitional epithelium.
The wall consists of thin layer of smooth
muscle and prominent outer circular straited
muscle fibers (rhabdosphincter) – form
external urethral sphincter.
23.
24. Spongy urethra:
16 cms long.
Extends from membranous urethra to
external urethral orifice.
Lined by pseudostratified columnar epi.
2 parts:
Bulbar urethra – surrounded by
bulbospongiosus – widest part.
Penile urethra – dilated part within the glans
– navicular fossa – lined by stratified
squamous epithelium.
27. Applied anatomy:Applied anatomy:
Commonly involved structure in urethral
syndromes of gonococcal and non-
gonococcal origin.
Gonococci have predilection for columnar
epithelium.
Inflammation of urethra is known as
‘urethritis’ – regarded as sexually transmitted
unless proven otherwise.
Urethritis often presents with urethral
discharge and dysuria.
Lab: increased PMNL in urethral dis. Smear.
30. Urethral strictures:
narrowing of the urethra caused by injury or
disease such as UTI.
can occur as complication of gonococcal
(hard strictures) and non gonococcal
urethritis ( soft strictures).
Early Syphilis, chancroid, herpes, TB,
bilharzia.
Trauma - can be physical (eg catheterization,
urethroscopy); Chemical (burns from
podophyllin ,TCA or diathermy).
31. Rupture Of Urethra:
commonly ruptured beneath the pubis by a
fall astride a sharp object leading to
extravasation of urine into peritoneum.
Hypospadias:
common anamoly in which urethra opens on
the undersurface of penis.
Epispadias:
rare condition in which urethra opens on the
dorsum of penis.
associated with ectopia vesicae
32. Spermatic cord:Spermatic cord:
As the testis traverses the abdominal wall
into the scrotum during early life, it carries
its vessels, nerves and vas deferens with it.
These meet at the deep inguinal ring to form
the ‘spermatic cord’.
In the canal, the cord acquires coverings
from abd. Wall layers.
Suspends the testis in scrotum and extends
from deep inguinal canal to the posterior
aspect of the testis.
33.
34. Contents of spermatic cord:
1. ductus deferens
2.testicular and cremasteric arteies and
artery of the ductus deferens.
3. pampiniform plexus of veins.
4. lymph vessels from the testis.
5. ilioinguinal nerve, genital branch of the
genitofemoral nerve, and the plexus of
sympathetic nerves around the artery to
ductus deferens and visceral afferent nerve
fibers.
6.remains of the processus vaginalis.
35.
36. Testes:Testes:
Primary reproductive organs or gonads.
Covered by 3 coats ( o i)
Tunica vaginalis
Tunica albuginea
Tunica vasculosa.
Produce sperm and testosterone.
Sperms – produced by seminiferous tubules.
Testosterone – by leydig cells located b/n the
tubules.
37.
38. 400-600 seminiferous tubules in each testes –
contain spermatogenic cells and supporting
sertoli cells.
Tubules join to form ‘rete testis’
Excretory duct system – 5 elements.
Testis
Efferent ducts
Epididymis
Vas
Ejaculatory duct and urethra.
39.
40. Applied anatomy:Applied anatomy:
Absence of testis:
u/l – monorchism
b/l – anorchism.
Undescended testis or cryptorchidism: may
lie in lumbar, iliac, inguinal, or upper scrotal
region.
May complete after birth.
Spermatogenesis may fail to occur in it.
More prone for malignancy.
Condition is surgically corrected.
41. Hermaphroditism:
Individual shows some features of male and
some of a female.
True – both testis+ ovary
Pseudo – gonad is of one sex while the
external or internal genitalia are of opposite
sex.
Carcinomas and infections: may be palpated
to check any nodules, or any irregularity or
size or consistency.
Varicocele: dilatation of pampiniform plexus
on veins.
43. Vas deferens:Vas deferens:
Distal continuation of
epididymis.
45 cms long.
At prostate base, vas
joins duct of seminal
vessel to form
ejaculatory duct.
Conveys sperm to the
ejaculatory ducts.
Applied anatomy: –
vasectomy - removing a
part under LA for family
planning.
44. Ejaculatory duct:Ejaculatory duct:
2 cms in length.
Starts from the base of the prostate and
ends on the verumontanum or within
the utricular opening.
45.
46. Seminal vesicles:Seminal vesicles:
Sacculated tubes located b/n the bladder
and the rectum.
Single coiled tube with irregular
diverticula.
Secrete alkaline, slightly yellowish viscid
fluid which constitutes 60-70% of the
ejaculatory volume.
47.
48. Prostate:Prostate:
Located b/n bladder neck and the urogenital
diaphragm.
Encircles the urethra completely.
Zones: 3
1. Periurethral zone – surrounding urethra.
2. central zone – wedge-shaped; bounded by
ejaculatory duct, urethra, and base of the
bladder.
Less susceptible to inflammatory,
hyperplastic, or neoplastic ds.
49. 3. peripheral/outer zone – the portion that is
palpable on rectal exmn.
Most frequently involved in carcinoma and
inflammation.
50. Secretions:
Thin, slightly opaque fluid.
Contributes to 30% of ejaculate volume.
Protects the male lower urinary tract against
infections.
Provides enzymes for ‘liquefying’ the semen
after ejaculation.
51. Applied anatomyApplied anatomy
Benign prostate hypertrophy:
senile enlargement after 50 years.
Occurs in periurethral zone.
Causes retention of urine due to distortion
of urethra.
Rx: prostatectomy – transvesical
transvesical/
retropubic/
transurethral
resection.
52. Prostatitis:
Acute or chronic inflammation.
Acute – sec. to gonococcal urethritis.
Chronic – tuberculous infection of
epididymis, seminal vesicles and the bladder.
Ca.prostate:
Occurs after the age of 50-55 years.
Symptoms are urinary obstruction, low
backpain or sciatica.
Rectal exmn – irregular hard prostate.
Mets spread to vertebral column.
53. Bulbourethral (cowper’s)glands:Bulbourethral (cowper’s)glands:
Paired, pea-sized glands located in urogenital
diaphragm.
Excretory ducts drain into posterior
urethra.
Secrete a thin, mucoid material during the
excitatory stage of sexual response.
Contribute a minimal amount to the
ejaculate.
Immune to hyperplastic and neoplastic ds.