This document discusses mucosal protective agents used to treat gastric ulcers, including sucralfate, prostaglandin analogs, and bismuth compounds. Sucralfate forms a protective barrier over ulcers that stimulates prostaglandin and bicarbonate secretion. Misoprostol, a prostaglandin analog, stimulates mucus and bicarbonate secretion to protect the mucosa. Bismuth compounds coat ulcers with a protective layer and have antimicrobial effects against H. pylori. These agents help promote healing of ulcers and protect the gastric mucosa from further damage.