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ModProt Diagnostics
ModProt Diagnostics has developed a new biomarker test for diagnosing lupus that could help address issues with current testing. Lupus is a chronic autoimmune disease that is difficult to diagnose, with the average patient waiting 6 years for a correct diagnosis. ModProt's new test detects antibodies to an estrogen-modified protein biomarker that is specific to lupus. This could allow for earlier and more accurate diagnosis of lupus compared to current nonspecific tests. The company plans to validate the test and develop it into a commercial product to benefit patients and lower healthcare costs.
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ModProt Diagnostics
- 1. A BREAKTHROUGH FORLUPUS DIAGNOSIS ModProt Diagnostics
- 2. ModProt Diagnostics PROBLEM LUPUS ISA CHRONIC AUTOIMMUNE DISEASE, A DEVASTATING DISEASE THAT CAN DAMAGE ANY ORGAN OR TISSUE 2 5M PEOPLE WORLDWIDE Lupus Foundation of America DIFFICULT TO DIAGNOSE See More than 4 Physicians Patients wait On Average Nearly 6 years for a correct diagnosis
- 3. Specific Biomarker ModProt Diagnostics SOLUTION 3 Incidence Menopause Puberty SeveritySex Hormones Lupus sufferers are female Lupus progression over time Antibody Biomarker Non-specific EARLIER DIAGNOSIS HIGH LEVELS ESTROGE NS IMMUNE RESPONSE ESTROGEN- MODIFIED KEY PROTEINS ANTIBODIES PRODUCTION DAMAGE
- 4. ModProt Diagnostics MARKET &COMPETITION 2.6 M new cases/year Centers for Disease Control and Prevention (CDC) Rheumatoid Arthritis 1.5 M Lupus 1.5 M Sjögren’s syndrome 0.4 to 3.1 M Fibromyalgia 5 M Ankylosing spondylitis 2.7 M Costs of current panel - $ 432 x 4-10 times $600 Cost per test based on both Cost-based and market-based Approaches ANTINUCLEAR ANTIBODY NON-SPECIFIC TEST $1.56B
- 5. 5 ModProt Diagnostics BUSINESS MODEL/ PROOPOSAL A TEST FOR LUPUS-SPECIFIC DIAGNOSIS Lupus-specific biomarker Accurate and Sensitive EndoMark PATIENT BENEFITS Earlier Lupus diagnosis Earlier Treatment Live longer Better Life quality HOSPITALS AND CLINICS Reduced healthcare costs Early Detection Saves & Improves lives
- 6. 6 300 K €Funding4.2 M € ModProt Diagnostics ROADMAP
- 7. 7 M1 Biomarker Specificity evaluation with 50 patients Jun 2017 M2 IP M5 Biomarker Specificity validation with250 Lupus Jul 2018 M4 Business Plan Dec 2017 M3 Gap Analysis Set 2017 Proof of Concept Aug 2017 ModProt Diagnostics ROADMAP
- 8. 8 300 K €Funding4.2 M € ModProt Diagnostics ROADMAP
- 9.
- 10. Cristina Jacob Alexandra Antunes JoãoRodrigues Technologists Scientific Advisors Jaime Branco, MD Fernando Pimentel, MD Sofia Pereira Members of the American College of Rheumatology 10 ModProt Diagnostics TEAM
- 11. 11 A breakthrough forLUPUS diagnosis Contact us modprotdx@gmail.com ModProt Diagnostics Helping Lupus Patients to Extend their Lives and Improve their Quality of Life EndoMark THANK YOU