[Note: This is a partial preview. To download this presentation, visit:
https://www.oeconsulting.com.sg/training-presentations]
This is a comprehensive set of checklists for waste-finding in manufacturing companies. The checklists are based on the eight types of Lean waste:
1. Overproduction
2. Inventory
3. Waiting
4. Motion
5. Transportation
6. Defects
7. Overprocessing
8. Intellectual
The checklists have a combined total of 65 waste items which could be potentially found on the shopfloor. For each checklist item, the magnitude of waste can be quantified under four levels:
Magnitude 0 : No waste found
Magnitude 1 : Very little waste
Magnitude 2 : Some waste
Magnitude 3 : A lot of waste
The checklists can be applied generally to all manufacturing departments. Users may adopt the checklists as they are, or customize them to suit your specific application. Add or delete the checklist items as needed.
The checklists form the basis of a structured improvement plan. Waste items can be ranked or prioritized and assigned to a person or team to develop an action plan for eliminating the identified waste within a certain timeframe.
CONTENTS:
1. Summary of the Eight Types of Lean Waste
2. Waste-finding Checklists
2.1 Waste-finding Checklist: Overproduction
2.2 Waste-finding Checklist: Inventory
2.3 Waste-finding Checklist: Waiting
2.4 Waste-finding Checklist: Motion
2.5 Waste-finding Checklist: Transportation
2.6 Waste-finding Checklist: Defects
2.7 Waste-finding Checklist: Overprocessing
2.8 Waste-finding Checklist: Intellectual
2.9 Major Waste-finding Checklist
This presentation describes the health challenges of adolescents, the approaches to interviewing an adolescent during a clinical encounter and the characteristics of an adolescent friendly health facility.
Explanation of what OEE and what the Six Big Losses are. Contermeasures to reduce the six losses. Calculation of OEE and six loss. How the XL800 tool can help you measure the components of OEE.
[Note: This is a partial preview. To download this presentation, visit:
https://www.oeconsulting.com.sg/training-presentations]
This is a comprehensive set of checklists for waste-finding in manufacturing companies. The checklists are based on the eight types of Lean waste:
1. Overproduction
2. Inventory
3. Waiting
4. Motion
5. Transportation
6. Defects
7. Overprocessing
8. Intellectual
The checklists have a combined total of 65 waste items which could be potentially found on the shopfloor. For each checklist item, the magnitude of waste can be quantified under four levels:
Magnitude 0 : No waste found
Magnitude 1 : Very little waste
Magnitude 2 : Some waste
Magnitude 3 : A lot of waste
The checklists can be applied generally to all manufacturing departments. Users may adopt the checklists as they are, or customize them to suit your specific application. Add or delete the checklist items as needed.
The checklists form the basis of a structured improvement plan. Waste items can be ranked or prioritized and assigned to a person or team to develop an action plan for eliminating the identified waste within a certain timeframe.
CONTENTS:
1. Summary of the Eight Types of Lean Waste
2. Waste-finding Checklists
2.1 Waste-finding Checklist: Overproduction
2.2 Waste-finding Checklist: Inventory
2.3 Waste-finding Checklist: Waiting
2.4 Waste-finding Checklist: Motion
2.5 Waste-finding Checklist: Transportation
2.6 Waste-finding Checklist: Defects
2.7 Waste-finding Checklist: Overprocessing
2.8 Waste-finding Checklist: Intellectual
2.9 Major Waste-finding Checklist
This presentation describes the health challenges of adolescents, the approaches to interviewing an adolescent during a clinical encounter and the characteristics of an adolescent friendly health facility.
Explanation of what OEE and what the Six Big Losses are. Contermeasures to reduce the six losses. Calculation of OEE and six loss. How the XL800 tool can help you measure the components of OEE.
Understanding Human Capabilities and Limitations: An Essential Ingredient For...Ronald G. Shapiro
Understanding Human Capabilities and Limitations: An Essential Ingredient For Ethical Management
A thorough understanding of what people can and cannot do is vital to ethically manage a business, school, government or not for profit agency.
Understanding Human Capabilities and Limitations develops that understanding through interactive activities which illustrate the human capabilities and limitations followed by a discussion of whether it would be ethical or unethical to ignore the concept discussed in:
.designing products
.managing employees
.promoting products
.working with our customers.
Participants will remember more from Understanding Human Capabilities and Limitations than from a traditional lecture and they will have more fun than at a typical party!!!
This presentation is the newest in the Games to Explain Human Factors: Come, Participate, Learn & Have Fun!!! Series
Champion: Jennifer Wolf
Semifinalists: Cassey LeBlanc, Christopher Dean & Theyab Ahehayan
Sponsors: Dr. Deborah S. Carstens & Dr. Roger Manley
Photos by: Michael Bluestein & Ron Shapiro
Florida Institute of Technology
November 3, 2009
CMI Sydney presentation Building Enterprise Change Capability - Top Global T...Prosci ANZ
In this interactive presentation, Being Human Managing Director Catherine Smithson will highlight the top global trends in the emerging field of Enterprise Change Management, using insights from Prosci’s recently released 2016 Best Practices in Change Management Benchmarking Report.
How to Leverage a license to Build Change Capability Webinar presented by Bei...Prosci ANZ
Research shows that establishing a common, structured approach to change management is second to only executive sponsorship in determining change management success. In this interactive webinar, we will dig deeper into research findings and look at practical ways to build on best practices to enhance your organisational change capability.
Technology & Human Development - A Capability ApproachIlse Oosterlaken
This is a lecture about my book Technology & Human Development (2015), in which well-being, agency and justice are the core values – as a powerful normative lens to examine technology and its role in development. This approach attaches central moral importance to individual human capabilities, understood as effective opportunities people have to lead the kind of lives they have reason to value. The book examines the strengths, limitations and versatility of the capability approach when applied to technology, and shows the need to supplement it with other approaches in order to deal with the challenges that technology raises.
The first chapter places the capability approach within the context of broader debates about technology and human development – discussing amongst others the appropriate technology movement. The middle part then draws on philosophy and ethics of technology in order to deepen our understanding of the relation between technical artefacts and human capabilities, arguing that we must simultaneously ‘zoom in’ on the details of technological design and ‘zoom out’ to see the broader socio-technical embedding of a technology. The book examines whether technology is merely a neutral instrument that expands what people can do and be in life, or whether technology transfers may also impose certain views of what it means to lead a good life. The final chapter examines the capability approach in relation to contemporary debates about ‘ICT for Development’ (ICT4D), as the technology domain where the approach has been most extensively applied so far.
Just a Room Full of Stuff? Why Libraries are Great / Katie BirkwoodKatie Birkwood
A brief introduction to what it is that makes libraries so important.
Talk given at Ignite London 4, 8 Feb 2011, with a bit of extra text added to help it make sense.
http://ignitelondon.net/home
UX, ethnography and possibilities: for Libraries, Museums and ArchivesNed Potter
These slides are adapted from a talk I gave at the Welsh Government's Marketing Awards for the LAM sector, in 2017.
It offers a primer on UX - User Experience - and how ethnography and design might be used in the library, archive and museum worlds to better understand our users. All good marketing starts with audience insight.
The presentation covers the following:
1) An introduction to UX
2) Ethnography, with definitions and examples of 7 ethnographic techniques
3) User-centred design and Design Thinking
4) Examples of UX-led changes made at institutions in the UK and Scandinavia
5) Next Steps - if you'd like to try out UX at your own organisation
The technologies and people we are designing experiences for are constantly changing, in most cases they are changing at a rate that is difficult keep up with. When we think about how our teams are structured and the design processes we use in light of this challenge, a new design problem (or problem space) emerges, one that requires us to focus inward. How do we structure our teams and processes to be resilient? What would happen if we looked at our teams and design process as IA’s, Designers, Researchers? What strategies would we put in place to help them be successful? This talk will look at challenges we face leading, supporting, or simply being a part of design teams creating experiences for user groups with changing technological needs.
Every decision we make is one made on behalf of your user. How do we know the decisions we make are the right ones? It is time we initiate a conversation: About where we are and where we want to go, about how we define and measure goodness and rightness in the digital realm, about responsibility, about decisions and consequences, about building something bigger than our own apps. It is time we talk about the ethics of web design. This talk introduces a method for ethical decision making in web design and tech. Rather than a wet moralistic blanket covering the fires of creativity, ethics can be the hearth that makes our creative fires burn brighter without burning down the house.
Presented at WordCamp Europe 2018: https://2018.europe.wordcamp.org/session/the-ethics-of-web-design/
Running head Intellectual and Sedentary Employment# .docxjeanettehully
Running head: Intellectual and Sedentary Employment<#>
Sedentary and Intellectual Employment Risks
08/03/2019
Sedentary and Intellectual Employment
Introduction
Workplaces all around the world are adopting sedentary working lifestyles. Healthcare
management occupation is one. These intellectual jobs require sedentary work. It can possibly be
viewed as a reward for required capabilities. There's pros and cons in intellectual and sedentary
employment. Here we'll mention a few. Healthcare management jobs are becoming only
available to those considered as intellectual. With the employee's intellectuality they're required
to call the shots, and do more sedentary labor than physical. Desk jobs, and office jobs fit the
description. Since they're already in the know they will create and manage plans to make sure a
job is carried out correctly. This is probably more elementary to them than it would be to
someone putting in physical labor, and vice versa. There's someone fit for everything.
If done right it can be the rise in a healthcare setting through quality and quantity. If it fails it can
be a catastrophic domino effect on the company and the employees. The con comes in when
those that hold intellectual and sedentary employment, have rarely, if ever, been on the outside of
the chair or office. It is easy to tell someone what to do. Can the person giving orders also carry
them out? Intellectual employment saves a lot of physical thinking and acting in humans. It
increases room for errors and road blocks. We should enforce physical labor being a requirement
to avoid harming our body and altering the employer's health.
The Sedentary Lifestyle Problem
It is very important for hospitals, or any healthcare setting to inform the employee of the
risks associated with their job description. Sedentary employment offers the benefit of not
standing over 6 hours out of an eight-hour work day. They are also permitted to only lift so many
Sedentary and Intellectual Employment
pounds. To most people this may sound enticing, it sounds like just the job that they’ll choose to
retire with. The disclaimer is that this is not compatible with the human body, interferes with
proper communication in the workplace, and can possibly lead up to lawsuits against the
company. Furthermore, sedentary employment does everything, but promote and contribute to a
healthy lifestyle. It isn’t “America friendly” because it also contributes to weight gain. For the
healthcare company it promotes faster service with the intelligence of technology, and outwit
competitors with being able to perform additional testing. These gadgets can handicap the mind
from doing what has been embedded in Western culture for survival, cognitively and critically
thinking. “Developing our abilities to think more clearly, richly, fully—individually and
collectively— is absolutely crucial to solving world prob ...
How to become a Security Behavior Alchemist – Global CISO Forum 2019 – Perry ...EC-Council
Behold the powers of behavioral alchemy! Are you ready to unleash 4 "Trojan Horses for the Mind" that will change the way you communicate forever? How about a magic wand that will help manifest secure behaviors and shape culture? Attend this session and harness the power.
Hybrid Workplace Harassment: Are You Protecting Your Company from Hidden Thre...Case IQ
In today’s “new world of work,” many organizations run on a hybrid model, with some employees working remotely and others in the physical office. While this set-up is convenient, it can cause unique interpersonal issues between employees.
Reduced face-to-face communication makes it harder for teams to bond, while making it easier for harassers to get away with bad behavior. To reduce harassment incidents in your hybrid workplace, you need to foster a culture of openness, willingness to learn, and compassion.
Join workplace investigation and executive management expert Kenneth McCarthy as he outlines how to address and prevent hybrid workplace harassment incidents.
Understanding Human Capabilities and Limitations: An Essential Ingredient For...Ronald G. Shapiro
Understanding Human Capabilities and Limitations: An Essential Ingredient For Ethical Management
A thorough understanding of what people can and cannot do is vital to ethically manage a business, school, government or not for profit agency.
Understanding Human Capabilities and Limitations develops that understanding through interactive activities which illustrate the human capabilities and limitations followed by a discussion of whether it would be ethical or unethical to ignore the concept discussed in:
.designing products
.managing employees
.promoting products
.working with our customers.
Participants will remember more from Understanding Human Capabilities and Limitations than from a traditional lecture and they will have more fun than at a typical party!!!
This presentation is the newest in the Games to Explain Human Factors: Come, Participate, Learn & Have Fun!!! Series
Champion: Jennifer Wolf
Semifinalists: Cassey LeBlanc, Christopher Dean & Theyab Ahehayan
Sponsors: Dr. Deborah S. Carstens & Dr. Roger Manley
Photos by: Michael Bluestein & Ron Shapiro
Florida Institute of Technology
November 3, 2009
CMI Sydney presentation Building Enterprise Change Capability - Top Global T...Prosci ANZ
In this interactive presentation, Being Human Managing Director Catherine Smithson will highlight the top global trends in the emerging field of Enterprise Change Management, using insights from Prosci’s recently released 2016 Best Practices in Change Management Benchmarking Report.
How to Leverage a license to Build Change Capability Webinar presented by Bei...Prosci ANZ
Research shows that establishing a common, structured approach to change management is second to only executive sponsorship in determining change management success. In this interactive webinar, we will dig deeper into research findings and look at practical ways to build on best practices to enhance your organisational change capability.
Technology & Human Development - A Capability ApproachIlse Oosterlaken
This is a lecture about my book Technology & Human Development (2015), in which well-being, agency and justice are the core values – as a powerful normative lens to examine technology and its role in development. This approach attaches central moral importance to individual human capabilities, understood as effective opportunities people have to lead the kind of lives they have reason to value. The book examines the strengths, limitations and versatility of the capability approach when applied to technology, and shows the need to supplement it with other approaches in order to deal with the challenges that technology raises.
The first chapter places the capability approach within the context of broader debates about technology and human development – discussing amongst others the appropriate technology movement. The middle part then draws on philosophy and ethics of technology in order to deepen our understanding of the relation between technical artefacts and human capabilities, arguing that we must simultaneously ‘zoom in’ on the details of technological design and ‘zoom out’ to see the broader socio-technical embedding of a technology. The book examines whether technology is merely a neutral instrument that expands what people can do and be in life, or whether technology transfers may also impose certain views of what it means to lead a good life. The final chapter examines the capability approach in relation to contemporary debates about ‘ICT for Development’ (ICT4D), as the technology domain where the approach has been most extensively applied so far.
Just a Room Full of Stuff? Why Libraries are Great / Katie BirkwoodKatie Birkwood
A brief introduction to what it is that makes libraries so important.
Talk given at Ignite London 4, 8 Feb 2011, with a bit of extra text added to help it make sense.
http://ignitelondon.net/home
UX, ethnography and possibilities: for Libraries, Museums and ArchivesNed Potter
These slides are adapted from a talk I gave at the Welsh Government's Marketing Awards for the LAM sector, in 2017.
It offers a primer on UX - User Experience - and how ethnography and design might be used in the library, archive and museum worlds to better understand our users. All good marketing starts with audience insight.
The presentation covers the following:
1) An introduction to UX
2) Ethnography, with definitions and examples of 7 ethnographic techniques
3) User-centred design and Design Thinking
4) Examples of UX-led changes made at institutions in the UK and Scandinavia
5) Next Steps - if you'd like to try out UX at your own organisation
The technologies and people we are designing experiences for are constantly changing, in most cases they are changing at a rate that is difficult keep up with. When we think about how our teams are structured and the design processes we use in light of this challenge, a new design problem (or problem space) emerges, one that requires us to focus inward. How do we structure our teams and processes to be resilient? What would happen if we looked at our teams and design process as IA’s, Designers, Researchers? What strategies would we put in place to help them be successful? This talk will look at challenges we face leading, supporting, or simply being a part of design teams creating experiences for user groups with changing technological needs.
Every decision we make is one made on behalf of your user. How do we know the decisions we make are the right ones? It is time we initiate a conversation: About where we are and where we want to go, about how we define and measure goodness and rightness in the digital realm, about responsibility, about decisions and consequences, about building something bigger than our own apps. It is time we talk about the ethics of web design. This talk introduces a method for ethical decision making in web design and tech. Rather than a wet moralistic blanket covering the fires of creativity, ethics can be the hearth that makes our creative fires burn brighter without burning down the house.
Presented at WordCamp Europe 2018: https://2018.europe.wordcamp.org/session/the-ethics-of-web-design/
Running head Intellectual and Sedentary Employment# .docxjeanettehully
Running head: Intellectual and Sedentary Employment<#>
Sedentary and Intellectual Employment Risks
08/03/2019
Sedentary and Intellectual Employment
Introduction
Workplaces all around the world are adopting sedentary working lifestyles. Healthcare
management occupation is one. These intellectual jobs require sedentary work. It can possibly be
viewed as a reward for required capabilities. There's pros and cons in intellectual and sedentary
employment. Here we'll mention a few. Healthcare management jobs are becoming only
available to those considered as intellectual. With the employee's intellectuality they're required
to call the shots, and do more sedentary labor than physical. Desk jobs, and office jobs fit the
description. Since they're already in the know they will create and manage plans to make sure a
job is carried out correctly. This is probably more elementary to them than it would be to
someone putting in physical labor, and vice versa. There's someone fit for everything.
If done right it can be the rise in a healthcare setting through quality and quantity. If it fails it can
be a catastrophic domino effect on the company and the employees. The con comes in when
those that hold intellectual and sedentary employment, have rarely, if ever, been on the outside of
the chair or office. It is easy to tell someone what to do. Can the person giving orders also carry
them out? Intellectual employment saves a lot of physical thinking and acting in humans. It
increases room for errors and road blocks. We should enforce physical labor being a requirement
to avoid harming our body and altering the employer's health.
The Sedentary Lifestyle Problem
It is very important for hospitals, or any healthcare setting to inform the employee of the
risks associated with their job description. Sedentary employment offers the benefit of not
standing over 6 hours out of an eight-hour work day. They are also permitted to only lift so many
Sedentary and Intellectual Employment
pounds. To most people this may sound enticing, it sounds like just the job that they’ll choose to
retire with. The disclaimer is that this is not compatible with the human body, interferes with
proper communication in the workplace, and can possibly lead up to lawsuits against the
company. Furthermore, sedentary employment does everything, but promote and contribute to a
healthy lifestyle. It isn’t “America friendly” because it also contributes to weight gain. For the
healthcare company it promotes faster service with the intelligence of technology, and outwit
competitors with being able to perform additional testing. These gadgets can handicap the mind
from doing what has been embedded in Western culture for survival, cognitively and critically
thinking. “Developing our abilities to think more clearly, richly, fully—individually and
collectively— is absolutely crucial to solving world prob ...
How to become a Security Behavior Alchemist – Global CISO Forum 2019 – Perry ...EC-Council
Behold the powers of behavioral alchemy! Are you ready to unleash 4 "Trojan Horses for the Mind" that will change the way you communicate forever? How about a magic wand that will help manifest secure behaviors and shape culture? Attend this session and harness the power.
Hybrid Workplace Harassment: Are You Protecting Your Company from Hidden Thre...Case IQ
In today’s “new world of work,” many organizations run on a hybrid model, with some employees working remotely and others in the physical office. While this set-up is convenient, it can cause unique interpersonal issues between employees.
Reduced face-to-face communication makes it harder for teams to bond, while making it easier for harassers to get away with bad behavior. To reduce harassment incidents in your hybrid workplace, you need to foster a culture of openness, willingness to learn, and compassion.
Join workplace investigation and executive management expert Kenneth McCarthy as he outlines how to address and prevent hybrid workplace harassment incidents.
An eBook full of great advice for Operations Business managers with many contributirs but organized and coordinated by Terry O'Hanlon from Reliabilityweb
EuroSTAR Software Testing Conference 2012 presentation on Curing Our Binary Disease by Rekard Edgren.
See more at: http://conference.eurostarsoftwaretesting.com/past-presentations/
Moving to the right side of safety is a journey; living a true culture of safety our goal. Sometimes it may feel like hiking up Everest without preparation; however, it doesn't have to be. Join us to explore this journey and inspire a passion for safety.
GlobeSync Technologies - Enterprise Business Solutions | Dedicated Professional | Digital Transformations | Silicon Engineering
Greetings,
I Hope you are doing well and have a wonderful new year. New year brings new opportunities and hope the pandemic could end in 2022 :) 🙏
Please accept my apologies for my cold message. My name is Viren, and I am a Business Manager for Global Sales at GlobeSync Technologies. I reached out to see if we could assist you with your software development needs (Mobile, Web, Cloud, IoT, Embedded, UI/UX etc.). As a 13-year-old Tempe, software engineering firm with a Team of 100+ professional, and globally presence in 9+ Countries, we work efficiently to deliver unique solutions to start-ups, other software development firms, enterprises, and digital agencies.
Maybe we can have a quick 15-minute call to discuss your upcoming digital initiatives and how we can help you streamline your development process and reduce costs while maintaining features, design, and quality.
Onboarding new resources and getting them up to speed on project details typically takes about 40 hours. We're willing to bear the cost of these 40 hours ourselves.
Our Core Services:
+ Product Development
+ Emerging Technologies Solutions
+ Mobile & Smart Device App Development
+ Software & Web Development
+ E-Commerce & CMS Development
+ Java Script Framework Development
+ AI-ML & IOT | Automation Solutions
+ UI / UX Design | Animation & Multimedia
+ Embeded & Hardware Engineering
+ Infra & DevOps Solutions
+ Cloud Services
+ Quality Engineering
+ Management | Media | Marketing
+ Maintenance | Upgrades | Support
+ IT Services & Staffing (Consulting)
The Company will be glad to provide you with all the necessary information at the most convenient time. Please Check out our website and portfolio,
Website: https://www.globesynctechnologies.com
Portfolio: https://www.globesynctechnologies.com/portfolio
Brochure | No More Paper :) - https://www.globesynctechnologies.com/wp-content/uploads/2021/11/GlobeSync-Technologies-Synchronizing-the-World.pdf
Thanks & Regards,
Viren
Business Manager | Global Sales
GlobeSync Technologies
Email: viren@globesynctechnologies.com
Skype: https://join.skype.com/invite/yAkJzoxlGIvL
Culture of Quality Bagladesh AAPS 8 August 2015 FinalAjaz Hussain
Why we are discussing Culture of Quality?
What is Culture of Quality?
How can it help?
The American public is facing unprecedented drug shortages and recalls (erosion of confidence)
Industry and the FDA have the shared obligation to reduce quality errors …
To fulfill this responsibility, both industry and the FDA need a culture of quality.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
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We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Hot Selling Organic intermediates
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MBBS (Best Graduate, AIMC Lahore)
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ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
11. Examples of defects
› Turn-around time beyond customer’s
expectation
› Wrong-site surgery
› Patient leaving ED without being seen
› Prescription filled incorrectly
› Patient dissatisfied with the food
› Lost specimen
› Any instance where we paid expedite
charges to mail something out
(e.g., used Fed Ex) when it wasn’t
necessary
Definitions
13. Mistake-Proofing Solutions
Prevention-based
› Senses an abnormality that is about
to happen and keeps it from
happening OR
› Keeps the process from moving
forward until all required elements
are present and correct
13
