Mauricio carrillo tripp
•
1 like•677 views
This document discusses computational biophysics, including current trends, needs, and challenges regarding high-performance computing (HPC). Computational biophysics uses physics-based modeling and simulation to study biological processes at the molecular level. Simulation sizes have increased from 20,000 atoms in 2000 to over 3 million atoms currently. Emerging needs include faster CPUs, solid state storage, and GPUs to analyze large simulation data in real time. Connectivity and infrastructure also need improvements to enable larger multicenter simulations. Overall, computational biophysics provides insights into cellular functions and mechanisms of life through increasingly detailed molecular simulations.
Report
Share
Report
Share
Download to read offline
Recommended
Microbial Genomics and Bioinformatics: BM405 (2015)
Slides from the University of Strathclyde BM405 guest lecture: Microbial Genomics and Bioinformatics, delivered 13th November 2015
Computational Genomics - Bioinformatics - IK
Computational genomics uses computational and statistical analysis to understand biology from genome sequences and related data. It involves analyzing whole genomes to understand how DNA controls organisms' molecular biology. The field emerged in the late 1990s with available complete genomes. It has contributed to discoveries like predicting gene locations, signaling networks, and genome evolution mechanisms. The first computer model of an organism was of Mycoplasma genitalium incorporating over 1,900 parameters. Computational genomics addresses problems like data storage, pattern matching, and structure prediction to analyze vast genomic data from databases.
Nanotechnology and Biotechnology
Deb Newberry, Director of the Nano-Link program at Dakota County Technical College, MN, talks about the exciting area where nanotechnology and biotechnology converge.
GENOMICS AND BIOINFORMATICS
Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble and analyze the function and structure of genomes
Bionanotechnology and its applications
Bionanotechnology combination of biotechnology and nanotechnology. Find its applications in various fields Nanotherapeutics, Gene therapy , Immunotherapy, Harmless Viruses, stem cells
Genomics and bioinformatics
Genomics is the study of genomes and includes determining entire DNA sequences, genetic mapping, and studying intragenomic phenomena. It allows determining an ideal genotype. Genomics and bioinformatics provide benefits like improved crop productivity, stress tolerance, and nutritional quality. Proteomics studies proteins in cells. Bioinformatics handles large genomic and proteomic data using algorithms. Structural genomics constructs sequence data and maps genes. Functional genomics studies gene function. Comparative genomics compares sequences to find relationships.
Sk microfluidics and lab on-a-chip-ch3
This document provides an overview of molecular biology concepts and analytical tools relevant to lab-on-a-chip applications in medical diagnostics. It describes the basic biological units of cells and DNA, as well as DNA analysis techniques like genome projects, DNA sequencing, and measuring gene expression using microarrays. Specific concepts covered include the central dogma of biology, DNA/RNA structure, genes and chromosomes, and how proteomics and single molecule DNA manipulation can be used for medical analysis.
Bioinformatics and functional genomics
Bioinformatics uses techniques from applied mathematics, computer science, and statistics to understand and organize biological information on a large scale, especially regarding molecules like DNA, RNA, and proteins. Functional genomics uses high-throughput methods and bioinformatics to describe gene and protein functions and interactions at a genome-wide level. Key tools for functional genomics include sequence-based tools, microarray-based tools, and Gene Ontology for organizing gene function information. A systems biology approach integrates vast amounts of correlative genomic and proteomic data to help understand complex human diseases.
Recommended
Microbial Genomics and Bioinformatics: BM405 (2015)
Slides from the University of Strathclyde BM405 guest lecture: Microbial Genomics and Bioinformatics, delivered 13th November 2015
Computational Genomics - Bioinformatics - IK
Computational genomics uses computational and statistical analysis to understand biology from genome sequences and related data. It involves analyzing whole genomes to understand how DNA controls organisms' molecular biology. The field emerged in the late 1990s with available complete genomes. It has contributed to discoveries like predicting gene locations, signaling networks, and genome evolution mechanisms. The first computer model of an organism was of Mycoplasma genitalium incorporating over 1,900 parameters. Computational genomics addresses problems like data storage, pattern matching, and structure prediction to analyze vast genomic data from databases.
Nanotechnology and Biotechnology
Deb Newberry, Director of the Nano-Link program at Dakota County Technical College, MN, talks about the exciting area where nanotechnology and biotechnology converge.
GENOMICS AND BIOINFORMATICS
Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble and analyze the function and structure of genomes
Bionanotechnology and its applications
Bionanotechnology combination of biotechnology and nanotechnology. Find its applications in various fields Nanotherapeutics, Gene therapy , Immunotherapy, Harmless Viruses, stem cells
Genomics and bioinformatics
Genomics is the study of genomes and includes determining entire DNA sequences, genetic mapping, and studying intragenomic phenomena. It allows determining an ideal genotype. Genomics and bioinformatics provide benefits like improved crop productivity, stress tolerance, and nutritional quality. Proteomics studies proteins in cells. Bioinformatics handles large genomic and proteomic data using algorithms. Structural genomics constructs sequence data and maps genes. Functional genomics studies gene function. Comparative genomics compares sequences to find relationships.
Sk microfluidics and lab on-a-chip-ch3
This document provides an overview of molecular biology concepts and analytical tools relevant to lab-on-a-chip applications in medical diagnostics. It describes the basic biological units of cells and DNA, as well as DNA analysis techniques like genome projects, DNA sequencing, and measuring gene expression using microarrays. Specific concepts covered include the central dogma of biology, DNA/RNA structure, genes and chromosomes, and how proteomics and single molecule DNA manipulation can be used for medical analysis.
Bioinformatics and functional genomics
Bioinformatics uses techniques from applied mathematics, computer science, and statistics to understand and organize biological information on a large scale, especially regarding molecules like DNA, RNA, and proteins. Functional genomics uses high-throughput methods and bioinformatics to describe gene and protein functions and interactions at a genome-wide level. Key tools for functional genomics include sequence-based tools, microarray-based tools, and Gene Ontology for organizing gene function information. A systems biology approach integrates vast amounts of correlative genomic and proteomic data to help understand complex human diseases.
Genomics and Bioinformatics
This document provides an overview of genomics, bioinformatics, and related topics. It discusses:
- The genomics and bioinformatics group members Amit Garg, Lokesh Joshi, and Pankaj Phogat.
- Definitions of genomics, genome, and bioinformatics.
- An overview of the human genome project including its history, goals of identifying and sequencing all human genes, and completion in 2003.
- Other completed genome projects such as for bacteria and yeast.
- The role of bioinformatics in collecting, organizing, analyzing, and sharing biological data through computational modeling, databases, and other tools.
Nanobots
Nanobots are tiny machines that can perform tasks at the nanoscale level. They are made from DNA and bacteria phages and have sizes around 10-9 meters. Different types of nanobots include respirocytes that act as artificial red blood cells, microbivores that act as white blood cells, and clottocytes that act as platelets. Nanobots have a variety of medical applications such as identifying and destroying cancer cells, clearing artery blockages, and repairing DNA and spinal cord issues. While nanobots show promise for rapid treatment, their replication needs to be carefully controlled and their use presents some economic and technical challenges.
Joe Betts-LaCroix at Health Extension Salon #1
Joe briefly summarizes what the recently announced ENCODE Project is, and the meaning of its preliminary results.
Nanotechnology in surgery
Nanotechnology has applications in surgery that could revolutionize how surgical procedures are performed. Nanorobots only 10-20 years away could operate at the molecular level and help tissues heal more gently. Lab-on-a-chip technologies using nanoparticles could provide targeted cancer detection and treatment. Bioprinting and 3D printing offer possibilities for creating artificial grafts and tissues that are indistinguishable from natural ones. However, risks also exist from unintended nanoparticle toxicity and potential for uncontrolled self-replicating nanorobots.
Sk microfluidics and lab on-a-chip-ch6
This document discusses cancer diagnostics and monitoring using microfluidic lab-on-a-chip technologies. It describes how integrating DNA/protein separation, detection, and analysis into microfluidic chips could allow for frequent, non-invasive testing of cancer biomarkers in blood or other bodily fluids. This would enable more precise monitoring of cancer treatment effectiveness and earlier detection of recurrence compared to standard techniques. The document outlines approaches involving microfluidic separation channels coupled to molecular detection and proposes a credit card-sized disposable chip sensor integrated with a small control unit for point-of-care cancer screening and monitoring.
Introduction to Bioinformatics
Dr. Jaume Bacardit gives an introduction to the field of bioinformatics. He defines bioinformatics as using computational techniques to understand biology by studying the information content and flow within biological systems. The document provides an overview of key topics in bioinformatics including molecular biology, public databases, sequence analysis, and biological data mining. It also introduces basic concepts such as DNA, RNA, proteins, and the central dogma of biology.
Fight with cancer using nanobots
The document discusses using nanorobots to fight cancer. Nanorobots are tiny machines that could be injected into patients to detect and destroy cancer cells without harming healthy cells. They would use biological sensors to locate tumors and contain enzymes to kill the cancer cells. While promising for inexpensive and painless treatment, nanorobots remain in early development stages and designing effective machines at the nanoscale is technically challenging.
encode project
The ENCODE Project was launched to interpret the human genome sequence generated by the Human Genome Project. It aims to identify all functional elements in the genome, including protein-coding genes as well as regulatory elements. The project involves mapping regions of transcription, transcription factor binding, chromatin structure, and histone modification across various cell types to assign biochemical functions to the genome. While early phases focused on developing appropriate techniques, the production phase is systematically annotating the entire genome. Future goals include expanding the dataset to more cell types to further understand gene regulation and its implications for human health.
Human genome project
The three sentence summary is:
The Human Genome Project aimed to map and sequence all the genes in the human genome between 1990-2003 through international collaboration, with the goals of identifying all human genes, determining their sequences and mapping genetic variations; two main strategies were used including a public hierarchical shotgun approach and a private whole genome shotgun by Celera; the results provided the complete human genome sequence and understanding of human genetic content and variation with applications to medicine like disease gene identification and new drug targets.
Biocomputing
Biocomputing is an interdisciplinary research area which combines biology, computer science, and engineering. It is the process of building computers that use biological materials. It uses systems of biologically derived molecules, such as proteins and DNA, to perform computational calculations. This paper provides a brief introduction to biocomputing. Matthew N. O. Sadiku | Nana K. Ampah | Sarhan M. Musa "Biocomputing" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-6 , October 2018, URL: http://www.ijtsrd.com/papers/ijtsrd18825.pdf
Arraygen bioinformatics ppt
ArrayGen Technologies Pvt Ltd is a Genomics service provider company with the wide array of expertise in Genomics algorithm development, next-generation sequencing(NGS), microarray and Bioinformatics services. Also, involved in various services in both industry and academia.
Course bionanotechnology and nanomedicin
This course covers bionanotechnology and nanomedicine. Topics include nanoparticle synthesis and applications in diagnostics and therapeutics. Techniques for patterning, microscopy, and biosensor functionalization will be discussed. Instructors will cover fundamental physics and chemistry of bionano materials, principles of microscopy, molecular nanotechnology, nanoparticle properties, and bio-nano imaging. Students will present on special topics and submit an essay on their presentation topic. The course meets twice weekly for 4 hours each session. Examinations include a presentation and essay due at the end of the course.
Yeast genome project
This is a compilation of the Yeast genome project from the different databases and sources.
By:
Nazish Nehal,
M. Tech (Biotechnology),
University School of Biotechnology (USBT),
Guru Gobind Singh Indraprastha University (GGSIPU),
New Delhi (INDIA)
Nanotechnology in surgery
An introduction to future therapeutics and nanorobots. Future of Surgery. For more go to http://www.nanotechgalaxy.com/
Introduction of bioinformatics
1. Bioinformatics is the science of using computer hardware and software to analyze biological data such as DNA sequences, protein sequences, and gene expression data.
2. It has three main branches - genomics which analyzes genome sequences, transcriptomics which analyzes gene expression data, and proteomics which analyzes protein sequences and structures.
3. The goals of bioinformatics include acquiring biological data, developing tools and databases, analyzing the data, and integrating different types of biological data to gain new biological insights.
Comparative genomics and proteomics
Comparative proteogenomics using mass spectrometry data from multiple genomes can address problems that a single genome approach cannot. It helps identify rare post-translational modifications, resolve "one-hit wonders" by looking for correlated peptides in orthologous proteins across species, and identify programmed frameshifts and sequencing errors. The approach is demonstrated through an analysis of mass spectrometry data from three Shewanella bacteria genomes, improving gene predictions and annotations compared to existing tools.
System's Biology
Systems biology is the computational and mathematical modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionism) to biological research.
Intro bioinfo
The document provides an introduction to the field of bioinformatics, including definitions, history, applications and key concepts. It discusses how bioinformatics uses computer algorithms and databases to analyze biological data like genomes, proteins and genes. Major databases that store DNA sequences are described, such as GenBank, EMBL and DDBJ. Tools for analyzing sequences like BLAST are also introduced.
Sk microfluidics and lab on-a-chip-ch1
This document provides an introduction to microfluidics and lab-on-a-chip technologies for biomedical applications. It discusses the basic principles of microsystems and microfabrication. Specifically, it describes how microsystems integrate electrical and other functions on the micrometer scale using microsensors and microactuators. The document also provides examples of biosensors and discusses the history and commercial applications of glucose biosensors. Finally, it suggests that the global market for biosensors and bioelectronics will continue growing significantly in the coming years as the technology develops.
Nanobots
The document discusses the potential for nanobots as therapeutic medical devices. It defines nanotechnology and nanorobotics, and describes how nanobots could be constructed at the nanoscale using materials like carbon. The document outlines several potential medical applications of nanobots, such as breaking up blood clots, targeted drug delivery, cancer therapy, and treating conditions like kidney stones and arteriosclerosis. It also discusses some advantages of nanobots like faster treatment and diagnosis with minimal side effects. However, the initial design costs are high and programming nanobots poses challenges. While still early in research, nanobots may revolutionize medicine if these challenges can be addressed.
An Easy Path to Exascale
Presented at the 2012 Salishan Conference on High-Speed Computing, "Random Access" session. Gleneden Beach, Oregon, 25 April 2012
LSS 2017 Frontiers in Metabolism
From systems physiology to precision medicine
Frontiers in metabolism
EMBO Press EPFL
the pathogenesis and management of the metabolic syndrome as a major medical challenge.
30 talks/speakers given by worldwide leaders in the metabolism field
Cell biology, signaling, metabolomics, physiology, genetics genomics and aging
innovative ideas
More Related Content
What's hot
Genomics and Bioinformatics
This document provides an overview of genomics, bioinformatics, and related topics. It discusses:
- The genomics and bioinformatics group members Amit Garg, Lokesh Joshi, and Pankaj Phogat.
- Definitions of genomics, genome, and bioinformatics.
- An overview of the human genome project including its history, goals of identifying and sequencing all human genes, and completion in 2003.
- Other completed genome projects such as for bacteria and yeast.
- The role of bioinformatics in collecting, organizing, analyzing, and sharing biological data through computational modeling, databases, and other tools.
Nanobots
Nanobots are tiny machines that can perform tasks at the nanoscale level. They are made from DNA and bacteria phages and have sizes around 10-9 meters. Different types of nanobots include respirocytes that act as artificial red blood cells, microbivores that act as white blood cells, and clottocytes that act as platelets. Nanobots have a variety of medical applications such as identifying and destroying cancer cells, clearing artery blockages, and repairing DNA and spinal cord issues. While nanobots show promise for rapid treatment, their replication needs to be carefully controlled and their use presents some economic and technical challenges.
Joe Betts-LaCroix at Health Extension Salon #1
Joe briefly summarizes what the recently announced ENCODE Project is, and the meaning of its preliminary results.
Nanotechnology in surgery
Nanotechnology has applications in surgery that could revolutionize how surgical procedures are performed. Nanorobots only 10-20 years away could operate at the molecular level and help tissues heal more gently. Lab-on-a-chip technologies using nanoparticles could provide targeted cancer detection and treatment. Bioprinting and 3D printing offer possibilities for creating artificial grafts and tissues that are indistinguishable from natural ones. However, risks also exist from unintended nanoparticle toxicity and potential for uncontrolled self-replicating nanorobots.
Sk microfluidics and lab on-a-chip-ch6
This document discusses cancer diagnostics and monitoring using microfluidic lab-on-a-chip technologies. It describes how integrating DNA/protein separation, detection, and analysis into microfluidic chips could allow for frequent, non-invasive testing of cancer biomarkers in blood or other bodily fluids. This would enable more precise monitoring of cancer treatment effectiveness and earlier detection of recurrence compared to standard techniques. The document outlines approaches involving microfluidic separation channels coupled to molecular detection and proposes a credit card-sized disposable chip sensor integrated with a small control unit for point-of-care cancer screening and monitoring.
Introduction to Bioinformatics
Dr. Jaume Bacardit gives an introduction to the field of bioinformatics. He defines bioinformatics as using computational techniques to understand biology by studying the information content and flow within biological systems. The document provides an overview of key topics in bioinformatics including molecular biology, public databases, sequence analysis, and biological data mining. It also introduces basic concepts such as DNA, RNA, proteins, and the central dogma of biology.
Fight with cancer using nanobots
The document discusses using nanorobots to fight cancer. Nanorobots are tiny machines that could be injected into patients to detect and destroy cancer cells without harming healthy cells. They would use biological sensors to locate tumors and contain enzymes to kill the cancer cells. While promising for inexpensive and painless treatment, nanorobots remain in early development stages and designing effective machines at the nanoscale is technically challenging.
encode project
The ENCODE Project was launched to interpret the human genome sequence generated by the Human Genome Project. It aims to identify all functional elements in the genome, including protein-coding genes as well as regulatory elements. The project involves mapping regions of transcription, transcription factor binding, chromatin structure, and histone modification across various cell types to assign biochemical functions to the genome. While early phases focused on developing appropriate techniques, the production phase is systematically annotating the entire genome. Future goals include expanding the dataset to more cell types to further understand gene regulation and its implications for human health.
Human genome project
The three sentence summary is:
The Human Genome Project aimed to map and sequence all the genes in the human genome between 1990-2003 through international collaboration, with the goals of identifying all human genes, determining their sequences and mapping genetic variations; two main strategies were used including a public hierarchical shotgun approach and a private whole genome shotgun by Celera; the results provided the complete human genome sequence and understanding of human genetic content and variation with applications to medicine like disease gene identification and new drug targets.
Biocomputing
Biocomputing is an interdisciplinary research area which combines biology, computer science, and engineering. It is the process of building computers that use biological materials. It uses systems of biologically derived molecules, such as proteins and DNA, to perform computational calculations. This paper provides a brief introduction to biocomputing. Matthew N. O. Sadiku | Nana K. Ampah | Sarhan M. Musa "Biocomputing" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-6 , October 2018, URL: http://www.ijtsrd.com/papers/ijtsrd18825.pdf
Arraygen bioinformatics ppt
ArrayGen Technologies Pvt Ltd is a Genomics service provider company with the wide array of expertise in Genomics algorithm development, next-generation sequencing(NGS), microarray and Bioinformatics services. Also, involved in various services in both industry and academia.
Course bionanotechnology and nanomedicin
This course covers bionanotechnology and nanomedicine. Topics include nanoparticle synthesis and applications in diagnostics and therapeutics. Techniques for patterning, microscopy, and biosensor functionalization will be discussed. Instructors will cover fundamental physics and chemistry of bionano materials, principles of microscopy, molecular nanotechnology, nanoparticle properties, and bio-nano imaging. Students will present on special topics and submit an essay on their presentation topic. The course meets twice weekly for 4 hours each session. Examinations include a presentation and essay due at the end of the course.
Yeast genome project
This is a compilation of the Yeast genome project from the different databases and sources.
By:
Nazish Nehal,
M. Tech (Biotechnology),
University School of Biotechnology (USBT),
Guru Gobind Singh Indraprastha University (GGSIPU),
New Delhi (INDIA)
Nanotechnology in surgery
An introduction to future therapeutics and nanorobots. Future of Surgery. For more go to http://www.nanotechgalaxy.com/
Introduction of bioinformatics
1. Bioinformatics is the science of using computer hardware and software to analyze biological data such as DNA sequences, protein sequences, and gene expression data.
2. It has three main branches - genomics which analyzes genome sequences, transcriptomics which analyzes gene expression data, and proteomics which analyzes protein sequences and structures.
3. The goals of bioinformatics include acquiring biological data, developing tools and databases, analyzing the data, and integrating different types of biological data to gain new biological insights.
Comparative genomics and proteomics
Comparative proteogenomics using mass spectrometry data from multiple genomes can address problems that a single genome approach cannot. It helps identify rare post-translational modifications, resolve "one-hit wonders" by looking for correlated peptides in orthologous proteins across species, and identify programmed frameshifts and sequencing errors. The approach is demonstrated through an analysis of mass spectrometry data from three Shewanella bacteria genomes, improving gene predictions and annotations compared to existing tools.
System's Biology
Systems biology is the computational and mathematical modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionism) to biological research.
Intro bioinfo
The document provides an introduction to the field of bioinformatics, including definitions, history, applications and key concepts. It discusses how bioinformatics uses computer algorithms and databases to analyze biological data like genomes, proteins and genes. Major databases that store DNA sequences are described, such as GenBank, EMBL and DDBJ. Tools for analyzing sequences like BLAST are also introduced.
Sk microfluidics and lab on-a-chip-ch1
This document provides an introduction to microfluidics and lab-on-a-chip technologies for biomedical applications. It discusses the basic principles of microsystems and microfabrication. Specifically, it describes how microsystems integrate electrical and other functions on the micrometer scale using microsensors and microactuators. The document also provides examples of biosensors and discusses the history and commercial applications of glucose biosensors. Finally, it suggests that the global market for biosensors and bioelectronics will continue growing significantly in the coming years as the technology develops.
Nanobots
The document discusses the potential for nanobots as therapeutic medical devices. It defines nanotechnology and nanorobotics, and describes how nanobots could be constructed at the nanoscale using materials like carbon. The document outlines several potential medical applications of nanobots, such as breaking up blood clots, targeted drug delivery, cancer therapy, and treating conditions like kidney stones and arteriosclerosis. It also discusses some advantages of nanobots like faster treatment and diagnosis with minimal side effects. However, the initial design costs are high and programming nanobots poses challenges. While still early in research, nanobots may revolutionize medicine if these challenges can be addressed.
What's hot (20)
Viewers also liked
An Easy Path to Exascale
Presented at the 2012 Salishan Conference on High-Speed Computing, "Random Access" session. Gleneden Beach, Oregon, 25 April 2012
LSS 2017 Frontiers in Metabolism
From systems physiology to precision medicine
Frontiers in metabolism
EMBO Press EPFL
the pathogenesis and management of the metabolic syndrome as a major medical challenge.
30 talks/speakers given by worldwide leaders in the metabolism field
Cell biology, signaling, metabolomics, physiology, genetics genomics and aging
innovative ideas
Future of medicine
Early humans began developing basic medical practices by using their senses to observe other primates and act on observations of grooming behaviors and nit-picking that addressed health issues. Over time, these social activities among primates transitioned into the beginnings of rudimentary human medicine as early humans applied their senses of sight, touch, smell, taste and hearing to identify health problems and ways to address them.
High Performance Computing - Challenges on the Road to Exascale Computing
The document discusses challenges in achieving exascale computing capabilities by 2018. It outlines how standard technology scaling will not be enough, and compromises will need to be made. These include reduced node performance, lower network bandwidth and fewer pins. Blue Gene architecture is presented as an example of a balanced system that achieves high performance through optimized interconnects and packaging density. A thought experiment proposes integrating significant solid state storage at each node to create an "active storage" machine based on Blue Gene architecture.
Exponential technology - How do we make sure everyone benefits?
Exponential technology - How do we make sure everyone benefits?
Democracy, democratic transhumanism, technoprogressivism, Exponential Technology How can we make sure everyone benefits? Dr. Matthijs Pontier
2. Content • Why should everyone benefit? • How do we make sure everyone benefits? • Democratic Transhumanism • Machine Ethics • When we succeed New ethical dilemma’s Matthijs Pontier, Leiden, 27-2-2016 Where is the boundary of the human? The new technological turn
3. Why should everyone benefit? Who is everyone? • Does life matter? Matthijs Pontier, Leiden, 27-2-2016Where is the boundary of the human? The new technological turn
4. Why should everyone benefit? Who is everyone? • What is life, anyway? Matthijs Pontier, Leiden, 27-2-2016
5. Why should everyone benefit? Who is everyone? • Does life matter? • What is life, anyway? • Does human life matter? Matthijs Pontier, Leiden, 27-2-2016
6. Why should everyone benefit? Who is everyone? • Does life matter? • What is life, anyway? • Does human life matter? • Do human individuals matter? Matthijs Pontier, Leiden, 27-2-2016
7. Why build technology? Matthijs Pontier, Leiden, 27-2-2016 Where is the boundary of the human? The new technological turn
8. Why build technology? Matthijs Pontier, Leiden, 27-2-2016 Where is the boundary of the human? The new technological turn
9. Why build technology?
10. Why build technology? Matthijs Pontier, Leiden, 27-2-2016 Where is the boundary of the human? The new technological turn
11. Why build technology? • Evolutionary progress • Preserve (human) life • To preserve human rights • To improve our well-being Matthijs Pontier, Leiden, 27-2-2016 Where is the boundary of the human? The new technological turn
12. Why build technology? • Evolutionary progress – Description of a process or goal in itself? • Preserve (human) life • To preserve human rights • To improve our well-being Matthijs Pontier, Leiden, 27-2-2016 Where is the boundary of the human? The new technological turn
13. Why build technology? • Evolutionary progress / Preserve humans • To preserve human rights • To improve our well-being • Hedonic utilitarianism? Matthijs Pontier, Leiden, 27-2-2016
14. Why build technology? • Evolutionary progress / Preserve humans • To preserve human rights • To improve our well-being • Hedonic utilitarianism? Matthijs Pontier, 15. Brave New World
17. How do we promote happiness?
18. Promoting happiness: Kill all unhappy people? 19. Promoting happiness: Improving autonomy? 20. How do we promote autonomy? • If everyone uses cognitive enhancers, do you still have a free choice to use it yourself?
1984, ai, autonomy, brave new world, democracy, democratic transhumanism, ethics, healthcare, human enhancement, huxley, ik ben alice, machine ethics, open source, orwell, philosophy, robots, science, tech, technology, technoprogressivism
Incredibleminds Career Exploration Laboratory
You are 15 years old. Imagine walking into a hip emporium that inspires you to be curious and energizes you to succeed at a career. You sit down and play games; learn how to build games, 3D worlds and simulations; or just chat with like-minded friends about the future. The entire experience is about helping you "visualize" your science and engineering career exploration. In a "design team setting" you "play" roles ranging from 3D modeler to aerospace engineer.
IncredibleMinds goes beyond college guidance and occupational information to address the entire process of STEM career assessment, exploration and action planning necessary to help minority youth find STEM careers that fit their skills, interests, personalities, and developmental needs. New educational solutions need to be relevant and valuable to industry as well as relevant and valuable to youth (National Association of Governors, 2006). The key to the future of education is leveraging current investments in entertainment software and industry technologies.
We use commercial video games as the conceptual bridge to “playing” with industry simulation and modeling tools. Modeling and simulation tools are the immersive environments that our next-generation engineers and scientists must master. These tools provide the means to design and build engineered systems as well as to investigate and visualize complex scientific phenomena. The modeling and simulation industry is a $6 billion U.S. industry that is central to innovation in high-growth industries and the advancement of scientific discovery. Today, Congressional and industry leaders consider the modeling and simulation industry a "national critical technology.” According to Dr. Edwin Crues, NASA Constellation Program Modeling and Simulation Architect, “We cannot have an active and vibrant space program without an active and vibrant modeling and simulation community to support it.”
Priyanka pillai-Tools for rare cancer data analytics
BioGridTM is a data integration portal that curates clinical, genomic, and other health data from various sources to enable its use for research while protecting privacy. Cart-WheelTM is a rare cancer database where patients can submit information about their rare tumor to facilitate research. A researcher studying small cell-ovarian cancer could access de-identified data from BioGridTM and collaborate with Cart-WheelTM to analyze genetic pathways and design treatment plans for patients with this rare cancer type.
Vivek wadhwa - Review
The document summarizes a workshop on exponential technologies held in Chihuahua, Mexico in 2016. Some key points made by speakers Vivek and Tarun Wadhwa include that exponential technologies will surpass human capacity in the next decade, Mexico could become the Silicon Valley of Latin America by capitalizing on these technologies, and that Chihuahua could develop industries in areas like telemedicine, 3D printing, robotics, and turning the city into a smart city. The workshop concluded with a discussion of billion dollar business ideas for Chihuahua and advice to understand problems and create solutions, make technologies convergent, and start with platforms rather than products.
Introduction to Artificial Intelligence
This document provides an introduction to artificial intelligence and how it can be applied to games. It discusses what AI is, common AI fields like machine learning and computer vision. It then focuses on AI for games, describing the components of an abstract AI agent model including sensors, actuators, and the environment. Actuators can include pathfinding, decision making and steering behaviors. The environment provides information to agents and can include resources, terrain and other units' positions. Finally, it outlines steps for building an AI game, such as determining the game type, choosing tools, designing objects, determining the number of agents, and separating agents from the environment.
Visual Analytics in Omics - why, what, how?
This document discusses visual analytics in omics data. It begins by noting the shift from hypothesis-driven to data-driven research due to large datasets. Visual analytics can help explore these data by opening the "black box" of algorithms and enabling researchers to develop hypotheses. Effective visualization leverages human perception through techniques like preattentive vision and Gestalt laws. Challenges to visual analytics include scalability issues for large datasets and identifying interesting patterns for further analysis. Examples demonstrate data exploration, filtering, and user-guided analysis in genomic applications.
Complementary and Alternative Therapies for Lupus
A presentation by Dr. Swamy Venuturupalli, MD, FACR from Lupus LA's annual patient education conference at Cedars Sinai Medical Center in Los Angeles, CA.
Dr. Swamy Venuturupalli is a board-certified rheumatologist practicing in Los Angeles. He is Clinical Chief of the Division of Rheumatology at Cedars Sinai Medical Center and Associate Clinical Professor of Medicine at UCLA as well as being Editor-in-Chief of Current Rheumatology Reports.
Dr. Venuturupalli grew up in Bombay, India, the son of two physicians. In 1995, he received his medical degree from the prestigious Topiwala National Medical College in Bombay. Dr. Venuturupalli completed his residency in Internal Medicine, with distinction, at the Upstate Medical University in Syracuse, NY. Following his residency, he was appointed Chief Resident in the department of medicine at Syracuse University, where he was in charge of managing and training 65 residents.
In 1999, Dr. Venuturupalli moved to Los Angeles for a combined fellowship in health services research with UCLA's School of Medicine, the RAND Corporation, and the Greater Los Angeles Veteran's Administration Medical Center. Along with his cohort, he conducted research on complementary and alternative medicine, publishing studies on Ayurvedic medicine, dietary supplements, and mind-body medicine. Dr. Venuturupalli then completed a rheumatology fellowship at the UCLA-Olive View medical program in 2002.
Dr. Venuturupalli's role as research investigator includes over a hundred clinical trials involving conditions such as lupus, rheumatoid arthritis, inflammatory muscle diseases, ankylosing spondylitis, etc. He participates in ongoing rheumatology research with Dr. Daniel Wallace, a leading physician in the field, at the Cedars Sinai Division of Rheumatology. Dr. Venuturupalli lectures frequently to the general public and to the staff and faculty at Cedars Sinai Hospital on various topics in rheumatology, including alternative and complementary medicine. He was also recently invited to give grand rounds at Cedars on topics such as antiphospholipid syndrome and myositis. Dr. Venuturupalli has authored numerous text-book chapters, is published in peer-reviewed journals, and is currently the Editor-in-Chief of the journal Current Rheumatology Reviews.
For the past eight years, Dr. Venuturupalli has held a private practice in association with a group of 4 rheumatologists. Dr. Venuturupalli is highly regarded by his colleagues and is a sought-after teacher in his field of expertise. He has served as the past president of the Southern California Rheumatology Society, a non-profit professional organization of rheumatologists focusing on professional education.
Areas of expertise: Inflammatory Muscle disease, Systemic Lupus Erythematosus, Anti- Phospholipid syndrome, Sjogren's syndrome, Osteoporosis, Vasculitis.
Xmed 2015 Lucien Engelen
This document discusses the impact of exponential technologies on healthcare and strategies for innovation. It notes that Radboud University Medical Center has grown significantly in recent years and was the first academic center outside the US to implement the EPIC electronic health records system. The author argues that innovations will accumulate rapidly with emerging technologies and that healthcare will become a software business. The document advocates for including patients in innovation efforts and highlights approaches like crowdsourcing research through a "MedCrowdFund" platform. It also discusses the need to educate students with a new curriculum focused on areas like e-health, social media, and flipped classrooms to better prepare them for technological changes in healthcare.
Biomedical Informatics Program -- Atlanta CTSA (ACTSI)
The Biomedical Informatics Program (BIP) aims to maximize the scientific impact of research proposals through four specific aims:
1) Developing interoperable applications and repositories to integrate multi-scale data across institutions.
2) Consulting with investigators to coordinate use of informatics tools.
3) Educating researchers on biomedical informatics principles and tools.
4) Developing novel informatics techniques for large data integration, semantic data extraction/transformation/loading, and testing data integrity in federated environments.
The BIP brings together researchers from Emory, Morehouse, and Georgia Tech to provide resources and training to enable collaborative, data-driven translational research across ACTSI institutions.
San Diego Venture Group; Venture Summit 2013; Smarr
Larry Smarr, Founding Director of the California Institute for Telecommunications and Information Technology (Calit2), shares his presentation delivered at Venture Summit Friday, July 12, 2013
Ex Med Companies Recap
This slide deck is a collection of companies during the Exponential Medicine 2016 Conference in San Diego.
Accelerating the Pace of Discovery Technical Computing at Intel
This document discusses how technical computing and high performance computing can help accelerate scientific discovery and address global challenges. It provides examples of how HPC is helping to make progress in areas like weather prediction, climate change research, energy exploration, and healthcare including genome mapping and cancer research. The document argues that technical computing will be crucial to achieving exascale computing capabilities and expanding access to HPC resources to further scientific insights.
San Diego Venture Group; Venture Summit 2013; Presnell
Organovo's Sharon Presnell, Ph.D., presents "Shaping the Future of Medicine…from better drugs to tissue on-demand"
Exponential Technology in Health Care
How advances in Exponential Technology are enabling entrepreneurs to do in Healthcare what was once only possible by government and large corporations.
Indiana 4 2011 Final Final
This document discusses integrating multi-scale data from pathology, radiology, and omics to characterize brain tumors. It outlines using algorithms to extract features from images at various scales, from cellular to tissue levels. Integrating these feature sets with clinical data and outcomes allows discovering molecular correlates and jointly predicting prognosis. Managing the large, heterogeneous data requires standardized formats and infrastructure to correlate multi-modal features and classify tumors.
Artificial intelligence
Artificial intelligence and machine learning are advancing rapidly. Neural networks allow computers to learn from large amounts of data through supervised, unsupervised, and reinforcement learning. Applications include computer vision, natural language processing, adaptive websites, speech recognition, and autonomous vehicles. Advancements have been enabled by cheap parallel computing, vast data availability, improved algorithms, and cloud infrastructure. Open questions remain around how neural networks work and how to ensure AI is beneficial to humanity.
Viewers also liked (20)
High Performance Computing - Challenges on the Road to Exascale Computing
High Performance Computing - Challenges on the Road to Exascale Computing
Exponential technology - How do we make sure everyone benefits?
Exponential technology - How do we make sure everyone benefits?
Priyanka pillai-Tools for rare cancer data analytics
Priyanka pillai-Tools for rare cancer data analytics
Biomedical Informatics Program -- Atlanta CTSA (ACTSI)
Biomedical Informatics Program -- Atlanta CTSA (ACTSI)
San Diego Venture Group; Venture Summit 2013; Smarr
San Diego Venture Group; Venture Summit 2013; Smarr
Accelerating the Pace of Discovery Technical Computing at Intel
Accelerating the Pace of Discovery Technical Computing at Intel
San Diego Venture Group; Venture Summit 2013; Presnell
San Diego Venture Group; Venture Summit 2013; Presnell
Similar to Mauricio carrillo tripp
Introduction
This document discusses biochips and their development. It begins with an introduction to biochips, noting they are miniaturized laboratories that can perform hundreds or thousands of biochemical reactions simultaneously. This enables rapid screening of biological analytes for various purposes. The document then provides history on the development of biosensor technologies and microarray fabrication techniques. It also discusses various types of microarrays beyond DNA, including protein, antibody, and chemical compound microarrays. Ethics regarding biotechnology development are briefly covered.
Living in a World of Nanobioinfotechnology
07.09.12
Invited Talk
Invitrogen
Title: Living in a World of Nanobioinfotechnology
Carlsbad, CA
Collins seattle-2014-final
In this deck from the 2014 HPC User Forum in Seattle, Jack Collins from the National Cancer Institute presents: Genomes to Structures to Function: The Role of HPC.
Watch the video presentation: http://wp.me/p3RLHQ-d28
K Zoo
The document discusses various advances in regenerative nanomedicine and human enhancement including tissue engineering using stem cells, biomaterials and biomolecules. It also describes several applications of nanotechnology for medical purposes such as nanofluidic chips for genome sequencing, nanopiezotronics for medical sensors and implants, and laser suturing. The discussion touches on some of the legal, ethical and safety issues regarding these emerging technologies.
K zoo presentation
The document discusses regenerative nanomedicine and human enhancement technologies including tissue engineering, stem cell research, nanofluidic chips, nanopiezotronics, laser suturing, cellular fusion, 3D printing of implants, bioMEMS, brain-computer interfaces, and nanobots. It also addresses some of the legal, ethical, and existential implications of these emerging technologies including issues around defining and transcending normal human abilities.
Living in a World of Nanobioinfotechnology
07.05.07
Invited Talk
OVP Venture Partners Technology Summit
Title: Living in a World of Nanobioinfotechnology
Seattle, WA
Sk microfluidics and lab on-a-chip-ch5
This document discusses Lab-on-a-Chip (LOC) technology and its applications in biomedical fields. LOC systems integrate full laboratory functions onto a single microchip to handle extremely small fluid volumes. Key points:
- LOCs deal with fluid transport and analysis on the microscale and are a type of microfluidic device. They can perform complex analyses like DNA separation and detection.
- LOC research grew in the 1990s as groups developed micropumps and sensors to integrate fluid processing. Genomics and military applications further drove research.
- LOCs have advantages like low sample/reagent use, fast analysis, compact size, and potential for point-of-care medical diagnostics. Examples include
China Medical University Student ePaper2
Microarray and bio-chips provide a new technology for analyzing samples in an instant, automatic, and high-efficiency way. Microarray biochips can be divided into DNA chips and protein chips. DNA chips use nucleic acids as probes to examine thousands of genes simultaneously, while protein chips use proteins, antibodies, or microorganisms as probes to detect factors like hormones. Microarray biochips allow many samples, reagents, and biological materials to react on a small, miniaturized device, generating data immediately after quantitative analysis. This technology is being developed for uses in medical diagnostics and drug development.
Fifty Years of Supercomputing: From Colliding Black Holes to Dynamic Microbio...
This document provides a summary of a lecture given by Dr. Larry Smarr on the past, present, and future of supercomputing over the last 50 years. The summary discusses:
- How Smarr solved equations for colliding black holes in the 1970s using a megaFLOPs computer, whereas today collisions are detected using petaFLOPs supercomputers - a billion fold increase in speed.
- How Smarr's research has evolved from modeling astrophysical phenomena to mapping the human gut microbiome using terabytes of sequencing data and hundreds of thousands of core-hours of supercomputing.
- Emerging trends in brain-inspired computing architectures and non-von Neumann systems that are better suited to tasks
An Overview of Microfluidics
This document provides an overview of microfluidics presented by Rajan Arora. It defines microfluidics as manipulating small amounts of fluids using channels 10-100 micrometers in size. Typical microfluidic systems are described including a DNA separation system and lab-on-a-chip for diagnosing heart attacks. The origins and history of microfluidics are discussed from Richard Feynman's 1959 talk to developments in the 1990s. Key components, physics principles, and flow mechanisms of microfluidic systems are explained. Various applications are highlighted such as lab-on-a-chip, low-cost paper and plastic-based microfluidics, and emerging uses in textiles, optofluidics and acou
Introduction to Biology for Engineers.pptx
Engineering undergraduates have to know the important of Biology for interdisciplinary invention and research.
Biochip (Bioinformatics & Biotechnology)
“Biochips” form the most exciting technology to emerge from the fields of Biotechnology, Electronics and Computers in recent years.
Advances in the areas of proteomics, genomics and pharmaceuticals are empowering scientists with new methods for unraveling the complex biochemical processes occurring within cells, with the larger goal of understanding and treating human diseases.
Almost simultaneously, the semiconductor industry has been steadily perfecting the science of micro-miniaturization.
NanoTechnology in the Field of Medicine.ppt
This document discusses the potential applications of nanotechnology in the field of medicine, including cell repair machines, drug delivery, and correcting genetic disorders. It describes how medical nanorobots could selectively target and destroy cancer cells or interrupt metabolism to induce a state of biostasis for surgery. While developing cell repair machines presents challenges and an exact timeline is unknown, ongoing research includes using porous polymer particles to inhale deliver drugs and self-assembling DNA scaffolds to arrange metallic nanoparticles for electronic devices. Potential issues that could arise include self-replicating nanobots posing a threat to humanity.
NanoTechnology in the Field of Medicine.ppt
This document discusses the potential applications of nanotechnology in the field of medicine, including cell repair machines, drug delivery, and correcting genetic disorders. It describes how medical nanorobots could selectively target and destroy cancer cells or interrupt metabolism to induce a state of biostasis for surgery. While developing cell repair machines presents challenges and an exact timeline is unknown, ongoing research includes using porous polymer particles to inhale deliver drugs and self-assembling DNA scaffolds to arrange metallic nanoparticles for electronic devices. Potential issues that could arise include self-replicating nanobots posing a threat to humanity.
NanoTechnology in the Field of Medicine.ppt
NanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Field of MediNanoTechnology in the Fie
Una estrategia para la integración de ontologías, servicios web y PLN en el a...
Conferencia presentada por el Ing. José López, como parte del X Coloquio Internacional de Tecnologías aplicadas a los Serivicios de Información
Kain042710 mit sloan-school
Ray Kurzweil presented on the acceleration of information technologies and paradigm shifts. He discussed how the price-performance of information technologies grows exponentially through multiple paradigm shifts, with the rate doubling every decade. He argued that limits to exponential growth are not very limiting due to ongoing paradigm shifts enabled by physics and emerging technologies like nanotechnology. Exponential growth will continue driving economic and technological change in coming decades according to the law of accelerating returns.
Synthetic biology, Artificial intelligence, quantum computing - in genetics
Importance and applications of synthetic biology, artificial intelligence, and quantum computers in genetics and recombinant DNA technology
Bioinformatics t1-introduction wim-vancriekinge_v2013
Bioinformatics is the application of information technology to the storage, management and analysis of biological information. It involves using computers to analyze biological data, especially DNA and protein sequences. Some key areas of bioinformatics include sequence analysis, molecular modeling, phylogeny/evolution, medical informatics, image analysis, and statistics. Bioinformatics has many applications in medicine like genome analysis for genetic diseases, understanding drug effects, and facilitating drug design. It can also be applied to crop and livestock improvement. Next generation sequencing technologies like Illumina, SOLiD, and 454 have enabled rapid DNA sequencing at a lower cost compared to Sanger sequencing. These new technologies are driving major advances in biological research.
Emerging Trends
The document discusses emerging trends at the convergence of engineering, biology, physics, and information technology including:
1) LifeChips that merge microelectronics and life sciences allowing medical devices to interface with living systems at the nanoscale.
2) Nanotechnology applications such as nano-structured porous silicon for cancer treatment and nanosensors integrated on a single chip.
3) Building computational models of organisms like E. Coli and using optical networks to interactively view genomic data at high resolutions.
4) Global research collaborations enabled by dedicated high-speed optical networks supporting applications like marine metagenomics and digital cinema telepresence.
Similar to Mauricio carrillo tripp (20)
Fifty Years of Supercomputing: From Colliding Black Holes to Dynamic Microbio...
Fifty Years of Supercomputing: From Colliding Black Holes to Dynamic Microbio...
Una estrategia para la integración de ontologías, servicios web y PLN en el a...
Una estrategia para la integración de ontologías, servicios web y PLN en el a...
Synthetic biology, Artificial intelligence, quantum computing - in genetics
Synthetic biology, Artificial intelligence, quantum computing - in genetics
Bioinformatics t1-introduction wim-vancriekinge_v2013
Bioinformatics t1-introduction wim-vancriekinge_v2013
More from guadalupe.moreno
Mateo valero p2
The document summarizes the performance of several supercomputers on the Green500 list from 2004 to 2011. It notes that the BG/Q system from 2011 had the highest performance on the list with 205 gigaflops per watt, greatly improving upon the BG/L from 2004 which achieved 0.33 gigaflops per watt. It also highlights that the MinoTauro system, based in Spain, was the highest ranked European system and 7th overall on the November 2011 Green500 list with an efficiency of 1266 megaflops per watt, demonstrating Europe's competitiveness in energy-efficient supercomputing.
Mateo valero p1
Riken's Fujitsu K computer is the world's fastest supercomputer, with a peak performance of over 11 petaflops. It uses a homogeneous architecture of over 700,000 SPARC64 VIIIfx processors connected via a high-speed interconnect. Looking ahead, future exascale supercomputers in the 2018 timeframe are projected to have over 1 exaflop of peak performance, use over 1 billion processing cores, and consume around 20 megawatts of power. Significant technological advancements will be required across hardware and software to achieve exascale capabilities.
Ron perrot
The document discusses developments in supercomputing, including the Top500 list which ranks the most powerful supercomputers in the world based on performance on LINPACK benchmarks. It provides details on the increasing performance of supercomputers over time, with the most powerful system in November 2011 being the K computer in Japan performing at 10.5 petaflops. The document also summarizes key details on some of the top 10 supercomputers from the 2011 Top500 list and discusses trends in supercomputing hardware and software.
Leonid sheremetov
This document summarizes a presentation about high performance computing (HPC) in the petroleum industry given by Dr. Leonid Sheremetov of the Mexican Petroleum Institute (IMP). It outlines the challenges of HPC in petroleum exploration and production. It provides an overview of IMP's research program in applied mathematics and computing, including their use of HPC. It then summarizes several of IMP's research projects applying HPC to problems in petroleum such as reservoir simulation, data mining of petroleum data, and distributed computing applications.
Hector duran limon
The LA Grid Initiative aims to develop collaboration and technology for hurricane mitigation through education, research, and talent development using high performance computing. It has helped develop collaboration networks and technology for disaster prediction since 2006. Better prediction models are needed to generate evacuation plans with finer-grained and timely predictions that can leverage federated computing resources like grids and clouds. The Weather Research and Forecasting model portal provides on-demand runs for meteorologists but performance must be increased for cloud computing. Challenges include supporting application-agnostic and platform-independent performance prediction for multicore and virtualized environments.
Celso garrido
1) The document discusses how high-performance computing (HPC) can drive innovation by allowing firms to manage risks through modeling, simulation, and analytics.
2) HPC provides powerful tools like distributed computing, virtualization, and graphics processing units that can lower costs and accelerate processes like design, testing, and production.
3) For HPC to fully enable innovation, barriers like skills gaps and viewing HPC as only a cost must be addressed, and HPC use should be considered within a national innovation system framework involving collaboration between public and private sectors.
Gerardo zavala guzman
The document summarizes the MINERvA experiment. It discusses (1) the MINERvA collaboration of over 120 physicists from 22 institutions in 7 countries, (2) the goals and components of the MINERvA detector located at Fermilab, and (3) the current status and timeline of the experiment, including accumulated neutrino and antineutrino data.
Andrey tchernykh
This document discusses the history and current state of high-performance computing (HPC) in Mexico. It outlines Mexico's first computer installation in 1958 and shows how the country has progressed, with Mexican universities and research centers appearing regularly in the Top 500 list since the 1990s. The document also examines HPC application areas in Mexico across various industries and concludes by emphasizing the importance of green computing practices like efficient algorithms, virtualization, and recycling to reduce environmental impact.
Agustin garcia reynoso
This document discusses air quality modeling using a high performance computing (HPC) system in Mexico. It describes the HPC system consisting of master and slave nodes used for air quality forecasting and climate change modeling. The system is used to model ozone levels and particulate matter for forecasting as well as evaluate the impacts of climate change and additional emissions sources on air quality in Mexico. Future work includes improving model nesting, dynamic emissions modeling, and leveraging new HPC technologies and parallel software.
Jf lavignon
1) Extreme computing poses major challenges for suppliers related to concurrency, energy usage, data management, and system resiliency as systems increase in size and complexity.
2) International cooperation is necessary to address these challenges as no single organization has a complete solution.
3) Bull promotes cooperation through partnerships, joint R&D labs, co-design with customers, and involvement in European programs like Systematic, Eureka, and FP7 to foster innovation.
Leonid sheremetov
The document summarizes a presentation about high performance computing applications in the petroleum industry given by Dr. Leonid Sheremetov of the Mexican Petroleum Institute. It discusses the challenges of exploration and production for PEMEX and outlines IMP's research program including grid-based simulation, data mining, and task optimization on clusters and desktop grids. Specific applications mentioned include reservoir simulation, seismic analysis, data mining of production data, electron microscopy, and a data mining project between IMP and other Mexican institutions.
More from guadalupe.moreno (11)
Recently uploaded
Apps Break Data
How information systems are built or acquired puts information, which is what they should be about, in a secondary place. Our language adapted accordingly, and we no longer talk about information systems but applications. Applications evolved in a way to break data into diverse fragments, tightly coupled with applications and expensive to integrate. The result is technical debt, which is re-paid by taking even bigger "loans", resulting in an ever-increasing technical debt. Software engineering and procurement practices work in sync with market forces to maintain this trend. This talk demonstrates how natural this situation is. The question is: can something be done to reverse the trend?
Northern Engraving | Nameplate Manufacturing Process - 2024
Manufacturing custom quality metal nameplates and badges involves several standard operations. Processes include sheet prep, lithography, screening, coating, punch press and inspection. All decoration is completed in the flat sheet with adhesive and tooling operations following. The possibilities for creating unique durable nameplates are endless. How will you create your brand identity? We can help!
What is an RPA CoE? Session 1 – CoE Vision
In the first session, we will review the organization's vision and how this has an impact on the COE Structure.
Topics covered:
• The role of a steering committee
• How do the organization’s priorities determine CoE Structure?
Speaker:
Chris Bolin, Senior Intelligent Automation Architect Anika Systems
Freshworks Rethinks NoSQL for Rapid Scaling & Cost-Efficiency
Freshworks creates AI-boosted business software that helps employees work more efficiently and effectively. Managing data across multiple RDBMS and NoSQL databases was already a challenge at their current scale. To prepare for 10X growth, they knew it was time to rethink their database strategy. Learn how they architected a solution that would simplify scaling while keeping costs under control.
[OReilly Superstream] Occupy the Space: A grassroots guide to engineering (an...
The typical problem in product engineering is not bad strategy, so much as “no strategy”. This leads to confusion, lack of motivation, and incoherent action. The next time you look for a strategy and find an empty space, instead of waiting for it to be filled, I will show you how to fill it in yourself. If you’re wrong, it forces a correction. If you’re right, it helps create focus. I’ll share how I’ve approached this in the past, both what works and lessons for what didn’t work so well.
Demystifying Knowledge Management through Storytelling
The Department of Veteran Affairs (VA) invited Taylor Paschal, Knowledge & Information Management Consultant at Enterprise Knowledge, to speak at a Knowledge Management Lunch and Learn hosted on June 12, 2024. All Office of Administration staff were invited to attend and received professional development credit for participating in the voluntary event.
The objectives of the Lunch and Learn presentation were to:
- Review what KM ‘is’ and ‘isn’t’
- Understand the value of KM and the benefits of engaging
- Define and reflect on your “what’s in it for me?”
- Share actionable ways you can participate in Knowledge - - Capture & Transfer
Essentials of Automations: Exploring Attributes & Automation Parameters
Building automations in FME Flow can save time, money, and help businesses scale by eliminating data silos and providing data to stakeholders in real-time. One essential component to orchestrating complex automations is the use of attributes & automation parameters (both formerly known as “keys”). In fact, it’s unlikely you’ll ever build an Automation without using these components, but what exactly are they?
Attributes & automation parameters enable the automation author to pass data values from one automation component to the next. During this webinar, our FME Flow Specialists will cover leveraging the three types of these output attributes & parameters in FME Flow: Event, Custom, and Automation. As a bonus, they’ll also be making use of the Split-Merge Block functionality.
You’ll leave this webinar with a better understanding of how to maximize the potential of automations by making use of attributes & automation parameters, with the ultimate goal of setting your enterprise integration workflows up on autopilot.
Main news related to the CCS TSI 2023 (2023/1695)
An English 🇬🇧 translation of a presentation to the speech I gave about the main changes brought by CCS TSI 2023 at the biggest Czech conference on Communications and signalling systems on Railways, which was held in Clarion Hotel Olomouc from 7th to 9th November 2023 (konferenceszt.cz). Attended by around 500 participants and 200 on-line followers.
The original Czech 🇨🇿 version of the presentation can be found here: https://www.slideshare.net/slideshow/hlavni-novinky-souvisejici-s-ccs-tsi-2023-2023-1695/269688092 .
The videorecording (in Czech) from the presentation is available here: https://youtu.be/WzjJWm4IyPk?si=SImb06tuXGb30BEH .
Columbus Data & Analytics Wednesdays - June 2024
Columbus Data & Analytics Wednesdays, June 2024 with Maria Copot 20
Mutation Testing for Task-Oriented Chatbots
Conversational agents, or chatbots, are increasingly used to access all sorts of services using natural language. While open-domain chatbots - like ChatGPT - can converse on any topic, task-oriented chatbots - the focus of this paper - are designed for specific tasks, like booking a flight, obtaining customer support, or setting an appointment. Like any other software, task-oriented chatbots need to be properly tested, usually by defining and executing test scenarios (i.e., sequences of user-chatbot interactions). However, there is currently a lack of methods to quantify the completeness and strength of such test scenarios, which can lead to low-quality tests, and hence to buggy chatbots.
To fill this gap, we propose adapting mutation testing (MuT) for task-oriented chatbots. To this end, we introduce a set of mutation operators that emulate faults in chatbot designs, an architecture that enables MuT on chatbots built using heterogeneous technologies, and a practical realisation as an Eclipse plugin. Moreover, we evaluate the applicability, effectiveness and efficiency of our approach on open-source chatbots, with promising results.
A Deep Dive into ScyllaDB's Architecture
This talk will cover ScyllaDB Architecture from the cluster-level view and zoom in on data distribution and internal node architecture. In the process, we will learn the secret sauce used to get ScyllaDB's high availability and superior performance. We will also touch on the upcoming changes to ScyllaDB architecture, moving to strongly consistent metadata and tablets.
"Choosing proper type of scaling", Olena Syrota
Imagine an IoT processing system that is already quite mature and production-ready and for which client coverage is growing and scaling and performance aspects are life and death questions. The system has Redis, MongoDB, and stream processing based on ksqldb. In this talk, firstly, we will analyze scaling approaches and then select the proper ones for our system.
Leveraging the Graph for Clinical Trials and Standards
Katja Glaß
OpenStudyBuilder Community Manager - Katja Glaß Consulting
Marius Conjeaud
Principal Consultant - Neo4j
Skybuffer SAM4U tool for SAP license adoption
Manage and optimize your license adoption and consumption with SAM4U, an SAP free customer software asset management tool.
SAM4U, an SAP complimentary software asset management tool for customers, delivers a detailed and well-structured overview of license inventory and usage with a user-friendly interface. We offer a hosted, cost-effective, and performance-optimized SAM4U setup in the Skybuffer Cloud environment. You retain ownership of the system and data, while we manage the ABAP 7.58 infrastructure, ensuring fixed Total Cost of Ownership (TCO) and exceptional services through the SAP Fiori interface.
JavaLand 2024: Application Development Green Masterplan
My presentation slides I used at JavaLand 2024
Session 1 - Intro to Robotic Process Automation.pdf
👉 Check out our full 'Africa Series - Automation Student Developers (EN)' page to register for the full program:
https://bit.ly/Automation_Student_Kickstart
In this session, we shall introduce you to the world of automation, the UiPath Platform, and guide you on how to install and setup UiPath Studio on your Windows PC.
📕 Detailed agenda:
What is RPA? Benefits of RPA?
RPA Applications
The UiPath End-to-End Automation Platform
UiPath Studio CE Installation and Setup
💻 Extra training through UiPath Academy:
Introduction to Automation
UiPath Business Automation Platform
Explore automation development with UiPath Studio
👉 Register here for our upcoming Session 2 on June 20: Introduction to UiPath Studio Fundamentals: https://community.uipath.com/events/details/uipath-lagos-presents-session-2-introduction-to-uipath-studio-fundamentals/
LF Energy Webinar: Carbon Data Specifications: Mechanisms to Improve Data Acc...
This LF Energy webinar took place June 20, 2024. It featured:
-Alex Thornton, LF Energy
-Hallie Cramer, Google
-Daniel Roesler, UtilityAPI
-Henry Richardson, WattTime
In response to the urgency and scale required to effectively address climate change, open source solutions offer significant potential for driving innovation and progress. Currently, there is a growing demand for standardization and interoperability in energy data and modeling. Open source standards and specifications within the energy sector can also alleviate challenges associated with data fragmentation, transparency, and accessibility. At the same time, it is crucial to consider privacy and security concerns throughout the development of open source platforms.
This webinar will delve into the motivations behind establishing LF Energy’s Carbon Data Specification Consortium. It will provide an overview of the draft specifications and the ongoing progress made by the respective working groups.
Three primary specifications will be discussed:
-Discovery and client registration, emphasizing transparent processes and secure and private access
-Customer data, centering around customer tariffs, bills, energy usage, and full consumption disclosure
-Power systems data, focusing on grid data, inclusive of transmission and distribution networks, generation, intergrid power flows, and market settlement data
AppSec PNW: Android and iOS Application Security with MobSF
Mobile Security Framework - MobSF is a free and open source automated mobile application security testing environment designed to help security engineers, researchers, developers, and penetration testers to identify security vulnerabilities, malicious behaviours and privacy concerns in mobile applications using static and dynamic analysis. It supports all the popular mobile application binaries and source code formats built for Android and iOS devices. In addition to automated security assessment, it also offers an interactive testing environment to build and execute scenario based test/fuzz cases against the application.
This talk covers:
Using MobSF for static analysis of mobile applications.
Interactive dynamic security assessment of Android and iOS applications.
Solving Mobile app CTF challenges.
Reverse engineering and runtime analysis of Mobile malware.
How to shift left and integrate MobSF/mobsfscan SAST and DAST in your build pipeline.
Recently uploaded (20)
Northern Engraving | Nameplate Manufacturing Process - 2024
Northern Engraving | Nameplate Manufacturing Process - 2024
Overcoming the PLG Trap: Lessons from Canva's Head of Sales & Head of EMEA Da...
Overcoming the PLG Trap: Lessons from Canva's Head of Sales & Head of EMEA Da...
Freshworks Rethinks NoSQL for Rapid Scaling & Cost-Efficiency
Freshworks Rethinks NoSQL for Rapid Scaling & Cost-Efficiency
[OReilly Superstream] Occupy the Space: A grassroots guide to engineering (an...
[OReilly Superstream] Occupy the Space: A grassroots guide to engineering (an...
Demystifying Knowledge Management through Storytelling
Demystifying Knowledge Management through Storytelling
Essentials of Automations: Exploring Attributes & Automation Parameters
Essentials of Automations: Exploring Attributes & Automation Parameters
Leveraging the Graph for Clinical Trials and Standards
Leveraging the Graph for Clinical Trials and Standards
JavaLand 2024: Application Development Green Masterplan
JavaLand 2024: Application Development Green Masterplan
Session 1 - Intro to Robotic Process Automation.pdf
Session 1 - Intro to Robotic Process Automation.pdf
LF Energy Webinar: Carbon Data Specifications: Mechanisms to Improve Data Acc...
LF Energy Webinar: Carbon Data Specifications: Mechanisms to Improve Data Acc...
AppSec PNW: Android and iOS Application Security with MobSF
AppSec PNW: Android and iOS Application Security with MobSF
Mauricio carrillo tripp
- 1. Computational Biophysics: current trends, needs and challenges in terms of HPC Mauricio Carrillo-Tripp trippm@langebio.cinvestav.mx Unidad LANGEBIO
- 2. Computational Biophysics: what is it? Bringing Physics to Life! • Apply the rigorous tools of physics to help uncover the fundamental mechanisms of life Theoretical & Computational Biophysics researchers have probed how cells do some of their fundamental tasks at the molecular level
- 3. Computational Biophysics: what does it do? • Interested in the physical mechanisms by which cellular processes function by combining theoretical and modeling methods, and by collaborating with experimental biologists. • Detailed three-dimensional structures of cell's macromolecules, pinpointing the position of the thousands of component atoms. • Those structures offer clues about how molecules act as motors, channels, solar cells, genetic switches, etc... All functions in life!
- 4. Computational Biophysics: how does it do it? • To begin explaining how a molecule functions, it is important to see it move! • Researchers have created software that simulates cell´s macromolecules at work. • Molecular-dynamics programs enable simulations using large-scale parallel machines with hundred to thousands of processors. • By developing algorithms and computing tools that help scientists visualize the movement of large biological molecules.
- 5. Computational Biophysics: Trends • Computer simulations of the biomolecular processes in human cells guide better understanding of health and disease. • Such simulations are extremely demanding and, in fact, all too often still limited by technological feasibility. • However, new Molecular Dynamics programs enable hundred- million-atom simulations in atomic detail, using the full capabilities of supercomputers due to parallel programming innovations and new technologies.
- 6. Computational Biophysics: Trends System size Use of GPUs Time
- 7. Computational Biophysics: Trends & highlights 2000 20K atoms G-proteins; Signaling, involved in numerous diseases and related to many targets of drugs.
- 8. Computational Biophysics: Trends & highlights 2001 100K atoms Aquaporins are channel proteins abundantly present in all life forms, defective forms are known to cause diseases.
- 9. Computational Biophysics: Trends & highlights 2003 220K atoms Mechanosensitive channel of small conductance (MscS), protects the cell against osmotic stress.
- 10. Computational Biophysics: Trends & highlights 2004 300K atoms Ankyrin, protein acting as an elastic spring in hearing.
- 11. Computational Biophysics: Trends & highlights 2005 400K atoms Translocation of DNA through alpha-hemolysin, a membrane protein with a narrow pore.
- 12. Computational Biophysics: Trends & highlights A new era in 2006 computational 1M atoms biology started! Satellite tobacco mosaic virus: the capsid (a protein shell), and a genome, consisting of either DNA or RNA.
- 13. Computational Biophysics: Trends & highlights 2009 3M atoms Complex between the ribosome and a protein-conducting channel that directs proteins into and across membranes.
- 14. Computational Biophysics: Needs Faster CPUs
- 15. Computational Biophysics: Needs • Solid state disk (SSD) technology is a extremely fast and large computer memory: storage medium to view and analyze on the fly Gigabytes-to-Terabytes of simulation data at the rate of up to 4 Gigabytes per second • Graphics Processing Units (GPUs) are increasingly being used, enabling computationally demanding simulation, visualization and analysis tasks. • Faster connection between processor nodes and high performance I/O nodes: Ultra fast switched fabric communications link with high throughput, low latency, quality of service, failover and scalable (InfiniBand).
- 16. Computational Biophysics: Challenges New frontier of physical life sciences - how individual components of the cell work together: Simulate a complete organelle or cell?? Engineering - by understanding the design principles of cellular machinery : "we are learning from nature how to design new bio-devices" Education - constructing a stronger bridge in Latin America - EU between people with expertise in Biology, Physics and Computing Sciences. Training.
- 17. HPC in Guanajuato Computational centers (cores): • Unidad Langebio - Cinvestav (600+3000) • CIMAT Gto (200+GPU) • Universidad de Guanajuato (2000) Grid project International Supercomputing Conference (2012)
- 18. www.isum.mx