SlideShare a Scribd company logo
1 of 18
TOPIC : SYSTEM’s
BIOLOG Y
TEAM : DOT TRIMATRIK
Submitted By:
I. Md. Ariful Islam (162-15-7885)
II. Pritam Chandra Shil (162-15-7882)
III. Sarwar Jahan Shajib (142-15-4045)

 What are systems Biology….??
Systems biology is
the Computational and Mathematical
modeling of complex biological
systems.
 Particularly from year 2000
onwards, the concept has been
used widely in biology in a variety
of contexts.
Example: Cells, Proteins

In molecular biology,
gene structure and
function
is studied at the
molecular level.
In systems biology,
specific interactions of
components in the biological
systems are studied –
cells, tissues, organs,
and ecological webs.
Molecular vs. Systems
Biology Biology


It is highly relevant in
discovering more complex
relationships involving multiple
genes.
This may create new
opportunities for drug discovery.
Advantages of Systems
Biology

Research has begun on larger-scale
simulations:
 Biochemical network level
 Simulation of Epidermal Growth
Factor (EGF)
 The Physio me Project
What’s to come?

Languages
Systems Biology Markup Language
CellML
Systems Biology Workbench
Databases
Kyoto Encyclopedia of Genes and Genomes
Alliance for Cellular Signaling
Signal Transduction Knowledge Environment
Databases and Tools

Protein 53
Produces 53 proteins kilo Daltons
Guardian of the genome
Detects DNA damages
p53

When multiple biological pathways
interact with each other, it is called
biological network.
Biological pathways are far more
complicated.
Have no real boundaries.
What’s the Biological Networks..?

Systems Biology
New?? NO and YES



Systems biology: studying living
cells/tissues/etc by exploring their
components and their interactions
Major challenge is to integrate knowledge
of kinetics and genome-scale networks
Even without detailed knowledge of
kinetics, genome-scale modeling is still
possible
Conclusions

ANY QUESTION….??

fashionable catchword?
a real new (philosophical) concept?
new discipline in biology?
just biology?
........
Hello Dear !! What is
systems Biology…??


More Related Content

What's hot

Comparative genomics
Comparative genomicsComparative genomics
Comparative genomics
hemantbreeder
 

What's hot (20)

Functional genomics
Functional genomicsFunctional genomics
Functional genomics
 
MULTIPLE SEQUENCE ALIGNMENT
MULTIPLE  SEQUENCE  ALIGNMENTMULTIPLE  SEQUENCE  ALIGNMENT
MULTIPLE SEQUENCE ALIGNMENT
 
Molecular phylogenetics
Molecular phylogeneticsMolecular phylogenetics
Molecular phylogenetics
 
Structural genomics
Structural genomicsStructural genomics
Structural genomics
 
LECTURE NOTES ON BIOINFORMATICS
LECTURE NOTES ON BIOINFORMATICSLECTURE NOTES ON BIOINFORMATICS
LECTURE NOTES ON BIOINFORMATICS
 
Introduction to systems biology
Introduction to systems biologyIntroduction to systems biology
Introduction to systems biology
 
Genomic databases
Genomic databasesGenomic databases
Genomic databases
 
Genome sequencing
Genome sequencingGenome sequencing
Genome sequencing
 
Transcriptomics and metabolomics
Transcriptomics and metabolomicsTranscriptomics and metabolomics
Transcriptomics and metabolomics
 
Genome annotation
Genome annotationGenome annotation
Genome annotation
 
Genome analysis
Genome analysisGenome analysis
Genome analysis
 
Transcriptomics
TranscriptomicsTranscriptomics
Transcriptomics
 
Secondary Structure Prediction of proteins
Secondary Structure Prediction of proteins Secondary Structure Prediction of proteins
Secondary Structure Prediction of proteins
 
String.pptx
String.pptxString.pptx
String.pptx
 
Primary and secondary databases ppt by puneet kulyana
Primary and secondary databases ppt by puneet kulyanaPrimary and secondary databases ppt by puneet kulyana
Primary and secondary databases ppt by puneet kulyana
 
Comparative genomics
Comparative genomicsComparative genomics
Comparative genomics
 
Secondary protein structure prediction
Secondary protein structure predictionSecondary protein structure prediction
Secondary protein structure prediction
 
Comparative genomics in eukaryotes, organelles
Comparative genomics in eukaryotes, organellesComparative genomics in eukaryotes, organelles
Comparative genomics in eukaryotes, organelles
 
Protein structure visualization tools-RASMOL
Protein structure visualization tools-RASMOLProtein structure visualization tools-RASMOL
Protein structure visualization tools-RASMOL
 
Bioinformatics
BioinformaticsBioinformatics
Bioinformatics
 

Similar to System's Biology

Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...
Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...
Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...
ijtsrd
 
application_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.pptapplication_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.ppt
shankjunk
 
application_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.pptapplication_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.ppt
shankjunk
 
Biological Significance of Gene Expression Data Using Similarity Based Biclus...
Biological Significance of Gene Expression Data Using Similarity Based Biclus...Biological Significance of Gene Expression Data Using Similarity Based Biclus...
Biological Significance of Gene Expression Data Using Similarity Based Biclus...
CSCJournals
 
I NTRODUCTION.doc
I NTRODUCTION.docI NTRODUCTION.doc
I NTRODUCTION.doc
butest
 

Similar to System's Biology (20)

Synthetic biology
Synthetic biology Synthetic biology
Synthetic biology
 
Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...
Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...
Eko Artificial Life, Determinacy of Ecological Resilience and Classification ...
 
Majority Voting Approach for the Identification of Differentially Expressed G...
Majority Voting Approach for the Identification of Differentially Expressed G...Majority Voting Approach for the Identification of Differentially Expressed G...
Majority Voting Approach for the Identification of Differentially Expressed G...
 
MAJORITY VOTING APPROACH FOR THE IDENTIFICATION OF DIFFERENTIALLY EXPRESSED G...
MAJORITY VOTING APPROACH FOR THE IDENTIFICATION OF DIFFERENTIALLY EXPRESSED G...MAJORITY VOTING APPROACH FOR THE IDENTIFICATION OF DIFFERENTIALLY EXPRESSED G...
MAJORITY VOTING APPROACH FOR THE IDENTIFICATION OF DIFFERENTIALLY EXPRESSED G...
 
Agent-based and Chemical-inspired Approaches for Multicellular Models
Agent-based and Chemical-inspired Approaches for Multicellular ModelsAgent-based and Chemical-inspired Approaches for Multicellular Models
Agent-based and Chemical-inspired Approaches for Multicellular Models
 
application_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.pptapplication_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.ppt
 
application_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.pptapplication_of_bioinformatics_in_various_fields.ppt
application_of_bioinformatics_in_various_fields.ppt
 
Tales from BioLand - Engineering Challenges in the World of Life Sciences
Tales from BioLand - Engineering Challenges in the World of Life SciencesTales from BioLand - Engineering Challenges in the World of Life Sciences
Tales from BioLand - Engineering Challenges in the World of Life Sciences
 
Bioinformatics
BioinformaticsBioinformatics
Bioinformatics
 
DISCOVERING DIFFERENCES IN GENDER-RELATED SKELETAL MUSCLE AGING THROUGH THE M...
DISCOVERING DIFFERENCES IN GENDER-RELATED SKELETAL MUSCLE AGING THROUGH THE M...DISCOVERING DIFFERENCES IN GENDER-RELATED SKELETAL MUSCLE AGING THROUGH THE M...
DISCOVERING DIFFERENCES IN GENDER-RELATED SKELETAL MUSCLE AGING THROUGH THE M...
 
systems bioligy.pptx
systems bioligy.pptxsystems bioligy.pptx
systems bioligy.pptx
 
Bms 2010
Bms 2010Bms 2010
Bms 2010
 
Bioinformatics
BioinformaticsBioinformatics
Bioinformatics
 
System Biology and Pathway Network.pptx
System Biology and Pathway Network.pptxSystem Biology and Pathway Network.pptx
System Biology and Pathway Network.pptx
 
Pcmd bioinformatics-lecture i
Pcmd bioinformatics-lecture iPcmd bioinformatics-lecture i
Pcmd bioinformatics-lecture i
 
Synthetic Biology: Foundations, Tools, Techniques, Challenges and Future Dire...
Synthetic Biology: Foundations, Tools, Techniques, Challenges and Future Dire...Synthetic Biology: Foundations, Tools, Techniques, Challenges and Future Dire...
Synthetic Biology: Foundations, Tools, Techniques, Challenges and Future Dire...
 
Bioinformatics and the logic of life
Bioinformatics and the logic of lifeBioinformatics and the logic of life
Bioinformatics and the logic of life
 
GET Conference at Arizona State University (25 May 2016)
GET Conference at Arizona State University (25 May 2016)GET Conference at Arizona State University (25 May 2016)
GET Conference at Arizona State University (25 May 2016)
 
Biological Significance of Gene Expression Data Using Similarity Based Biclus...
Biological Significance of Gene Expression Data Using Similarity Based Biclus...Biological Significance of Gene Expression Data Using Similarity Based Biclus...
Biological Significance of Gene Expression Data Using Similarity Based Biclus...
 
I NTRODUCTION.doc
I NTRODUCTION.docI NTRODUCTION.doc
I NTRODUCTION.doc
 

More from Pritam Shil

More from Pritam Shil (11)

Series Circuit
Series Circuit Series Circuit
Series Circuit
 
Internet Life ( History)
Internet Life ( History)Internet Life ( History)
Internet Life ( History)
 
Relativity Law ( Albert Einstein)
Relativity Law ( Albert Einstein) Relativity Law ( Albert Einstein)
Relativity Law ( Albert Einstein)
 
Isomorphism (Graph)
Isomorphism (Graph) Isomorphism (Graph)
Isomorphism (Graph)
 
System Software
System Software System Software
System Software
 
Result processing system (Project)
Result processing system (Project) Result processing system (Project)
Result processing system (Project)
 
Internal Architecture of 8086
Internal Architecture of 8086 Internal Architecture of 8086
Internal Architecture of 8086
 
EDC ( P-type & N-type )
EDC ( P-type & N-type )EDC ( P-type & N-type )
EDC ( P-type & N-type )
 
Digital electronics- BCD & Decoder
Digital electronics- BCD & DecoderDigital electronics- BCD & Decoder
Digital electronics- BCD & Decoder
 
Bisection Method
Bisection Method Bisection Method
Bisection Method
 
How to make a paper bird
How to make a paper birdHow to make a paper bird
How to make a paper bird
 

Recently uploaded

Warming the earth and the atmosphere.pptx
Warming the earth and the atmosphere.pptxWarming the earth and the atmosphere.pptx
Warming the earth and the atmosphere.pptx
GlendelCaroz
 
Heat Units in plant physiology and the importance of Growing Degree days
Heat Units in plant physiology and the importance of Growing Degree daysHeat Units in plant physiology and the importance of Growing Degree days
Heat Units in plant physiology and the importance of Growing Degree days
Brahmesh Reddy B R
 
Electricity and Circuits for Grade 9 students
Electricity and Circuits for Grade 9 studentsElectricity and Circuits for Grade 9 students
Electricity and Circuits for Grade 9 students
levieagacer
 

Recently uploaded (20)

Vital Signs of Animals Presentation By Aftab Ahmed Rahimoon
Vital Signs of Animals Presentation By Aftab Ahmed RahimoonVital Signs of Animals Presentation By Aftab Ahmed Rahimoon
Vital Signs of Animals Presentation By Aftab Ahmed Rahimoon
 
Harry Coumnas Thinks That Human Teleportation is Possible in Quantum Mechanic...
Harry Coumnas Thinks That Human Teleportation is Possible in Quantum Mechanic...Harry Coumnas Thinks That Human Teleportation is Possible in Quantum Mechanic...
Harry Coumnas Thinks That Human Teleportation is Possible in Quantum Mechanic...
 
MSCII_ FCT UNIT 5 TOXICOLOGY.pdf
MSCII_              FCT UNIT 5 TOXICOLOGY.pdfMSCII_              FCT UNIT 5 TOXICOLOGY.pdf
MSCII_ FCT UNIT 5 TOXICOLOGY.pdf
 
Towards a revolution in the social sciences FINAL FINAL FINAL FINAL FINAL.pdf
Towards a revolution in the social sciences FINAL FINAL FINAL FINAL FINAL.pdfTowards a revolution in the social sciences FINAL FINAL FINAL FINAL FINAL.pdf
Towards a revolution in the social sciences FINAL FINAL FINAL FINAL FINAL.pdf
 
Warming the earth and the atmosphere.pptx
Warming the earth and the atmosphere.pptxWarming the earth and the atmosphere.pptx
Warming the earth and the atmosphere.pptx
 
PARENTAL CARE IN FISHES.pptx for 5th sem
PARENTAL CARE IN FISHES.pptx for 5th semPARENTAL CARE IN FISHES.pptx for 5th sem
PARENTAL CARE IN FISHES.pptx for 5th sem
 
Costs to heap leach gold ore tailings in Karamoja region of Uganda
Costs to heap leach gold ore tailings in Karamoja region of UgandaCosts to heap leach gold ore tailings in Karamoja region of Uganda
Costs to heap leach gold ore tailings in Karamoja region of Uganda
 
Heat Units in plant physiology and the importance of Growing Degree days
Heat Units in plant physiology and the importance of Growing Degree daysHeat Units in plant physiology and the importance of Growing Degree days
Heat Units in plant physiology and the importance of Growing Degree days
 
Factor Causing low production and physiology of mamary Gland
Factor Causing low production and physiology of mamary GlandFactor Causing low production and physiology of mamary Gland
Factor Causing low production and physiology of mamary Gland
 
ABHISHEK ANTIBIOTICS PPT MICROBIOLOGY // USES OF ANTIOBIOTICS TYPES OF ANTIB...
ABHISHEK ANTIBIOTICS PPT MICROBIOLOGY  // USES OF ANTIOBIOTICS TYPES OF ANTIB...ABHISHEK ANTIBIOTICS PPT MICROBIOLOGY  // USES OF ANTIOBIOTICS TYPES OF ANTIB...
ABHISHEK ANTIBIOTICS PPT MICROBIOLOGY // USES OF ANTIOBIOTICS TYPES OF ANTIB...
 
X-rays from a Central “Exhaust Vent” of the Galactic Center Chimney
X-rays from a Central “Exhaust Vent” of the Galactic Center ChimneyX-rays from a Central “Exhaust Vent” of the Galactic Center Chimney
X-rays from a Central “Exhaust Vent” of the Galactic Center Chimney
 
Terpineol and it's characterization pptx
Terpineol and it's characterization pptxTerpineol and it's characterization pptx
Terpineol and it's characterization pptx
 
Taphonomy and Quality of the Fossil Record
Taphonomy and Quality of the  Fossil RecordTaphonomy and Quality of the  Fossil Record
Taphonomy and Quality of the Fossil Record
 
Soil and Water Conservation Engineering (SWCE) is a specialized field of stud...
Soil and Water Conservation Engineering (SWCE) is a specialized field of stud...Soil and Water Conservation Engineering (SWCE) is a specialized field of stud...
Soil and Water Conservation Engineering (SWCE) is a specialized field of stud...
 
Adaptive Restore algorithm & importance Monte Carlo
Adaptive Restore algorithm & importance Monte CarloAdaptive Restore algorithm & importance Monte Carlo
Adaptive Restore algorithm & importance Monte Carlo
 
Efficient spin-up of Earth System Models usingsequence acceleration
Efficient spin-up of Earth System Models usingsequence accelerationEfficient spin-up of Earth System Models usingsequence acceleration
Efficient spin-up of Earth System Models usingsequence acceleration
 
SaffronCrocusGenomicsThessalonikiOnlineMay2024TalkOnline.pptx
SaffronCrocusGenomicsThessalonikiOnlineMay2024TalkOnline.pptxSaffronCrocusGenomicsThessalonikiOnlineMay2024TalkOnline.pptx
SaffronCrocusGenomicsThessalonikiOnlineMay2024TalkOnline.pptx
 
GBSN - Biochemistry (Unit 3) Metabolism
GBSN - Biochemistry (Unit 3) MetabolismGBSN - Biochemistry (Unit 3) Metabolism
GBSN - Biochemistry (Unit 3) Metabolism
 
THE FUNDAMENTAL UNIT OF LIFE CLASS IX.ppt
THE FUNDAMENTAL UNIT OF LIFE CLASS IX.pptTHE FUNDAMENTAL UNIT OF LIFE CLASS IX.ppt
THE FUNDAMENTAL UNIT OF LIFE CLASS IX.ppt
 
Electricity and Circuits for Grade 9 students
Electricity and Circuits for Grade 9 studentsElectricity and Circuits for Grade 9 students
Electricity and Circuits for Grade 9 students
 

System's Biology

  • 1. TOPIC : SYSTEM’s BIOLOG Y TEAM : DOT TRIMATRIK
  • 2. Submitted By: I. Md. Ariful Islam (162-15-7885) II. Pritam Chandra Shil (162-15-7882) III. Sarwar Jahan Shajib (142-15-4045)
  • 3.   What are systems Biology….?? Systems biology is the Computational and Mathematical modeling of complex biological systems.  Particularly from year 2000 onwards, the concept has been used widely in biology in a variety of contexts. Example: Cells, Proteins
  • 4.  In molecular biology, gene structure and function is studied at the molecular level. In systems biology, specific interactions of components in the biological systems are studied – cells, tissues, organs, and ecological webs. Molecular vs. Systems Biology Biology
  • 5.
  • 6.  It is highly relevant in discovering more complex relationships involving multiple genes. This may create new opportunities for drug discovery. Advantages of Systems Biology
  • 7.  Research has begun on larger-scale simulations:  Biochemical network level  Simulation of Epidermal Growth Factor (EGF)  The Physio me Project What’s to come?
  • 8.  Languages Systems Biology Markup Language CellML Systems Biology Workbench Databases Kyoto Encyclopedia of Genes and Genomes Alliance for Cellular Signaling Signal Transduction Knowledge Environment Databases and Tools
  • 9.  Protein 53 Produces 53 proteins kilo Daltons Guardian of the genome Detects DNA damages p53
  • 10.  When multiple biological pathways interact with each other, it is called biological network. Biological pathways are far more complicated. Have no real boundaries. What’s the Biological Networks..?
  • 11.
  • 13.
  • 14.
  • 15.  Systems biology: studying living cells/tissues/etc by exploring their components and their interactions Major challenge is to integrate knowledge of kinetics and genome-scale networks Even without detailed knowledge of kinetics, genome-scale modeling is still possible Conclusions
  • 17.  fashionable catchword? a real new (philosophical) concept? new discipline in biology? just biology? ........ Hello Dear !! What is systems Biology…??
  • 18.