The document discusses material safety data sheets (MSDS), which provide detailed health and safety information about chemical products. It explains that MSDS have standardized 16-section formats covering topics like product identification, hazards, composition, safe handling/storage, exposure risks, and emergency procedures. The document also outlines common hazard labels used on chemicals, reviews the sections of a typical MSDS, and discusses personal protective equipment (PPE) worn by workers when engineering controls don't eliminate hazards.

1. INDUSTRIAL SAFETY
MATERIAL SAFETY
DATA SHEET
(PHARMACEUTICAL PROCESS CHEMISTRY)
PRESENTED BY
VISHAL DADARAO DAKHALE
M.PHARM SEM II
PHARMACEUTICAL CHEMISTRY DEPARTMENT
PRIYADARSHINI J. L. COLLEGE OF PHARMACY
Electronics Zone Building, MIDC, Hingna Road, Nagpur – 440 016. (Maharashtra)
(2018-19)

2. C ONTENTS
 INTRODUCTION
 MATERIAL SAFETY DATA SHEET (MSDS) FORM
 SECTIONS OF MSDS
 HAZARD LABELS OF CHEMICALS
 PERSONAL PROTECTION EQUIPMENT (PPE)
 REFERENCES

3. INTRODUCTION
 A material safety data sheet is a technical document which provides detailed and comprehensive
information on a controlled product related to:
 Health Effects Of Exposure To The Product
 Hazard Evaluation Related To The Product’s Handling, Storage Or Use
 Measure To Protect Workers At Risk Of Exposure
 Emergency Procedures.
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4.  The data sheet may be written, printed or otherwise expressed, and must meet the availability,
design and content requirements of WHMIS legislation. The legislation provides for flexibility
of design and wording but requires that a minimum number of categories of information be
completed and that all hazardous ingredients meeting certain criteria be listed subject to
exemptions granted under the Hazardous Materials Information Review Act.
 THE PURPOSE OF THE DATA SHEET :
 The data sheet is the second element of the WHMIS information delivery system and is
intended to supplement the alert information provided on labels. The third element of the
system is the education of employees in hazard information on controlled products, including
instruction in the content and significance of information on the MSDS.
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5. MSDS FORM 5

6. SECTIONS OF MSDS
 The MSDS follows a 16 section format which is internationally agreed and for substances
especially, the MSDS should be followed with an Annex which contains the exposure scenarios
of this particular substance. The 16 sections are:
 SECTION I : Identification of the substance/mixture and of the company/undertaking
 Product identifier
 Relevant identified uses of the substance or mixture and uses advised against
 Details of the supplier of the safety data sheet
 Emergency telephone number
 SECTION II : Hazards identification
 Classification of the substance or mixture
 Label elements
 Other hazards
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7.  SECTION III : Composition/information on ingredients
 Substances
 Mixtures
 SECTION IV : First aid measures
 Description of first aid measures
 Most important symptoms and effects, both acute and delayed
 Indication of any immediate medical attention and special treatment needed
 SECTION V : Fire fighting measures
 Extinguishing media
 Special hazards arising from the substance or mixture
 Advice for fire fighters
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8.  SECTION VI : Accidental release measure
 Personal precautions, protective equipment and emergency procedures
 Environmental precautions
 Methods and material for containment and cleaning up
 Reference to other sections
 SECTION VII : Handling and storage
 Precautions for safe handling
 Conditions for safe storage, including any incompatibilities
 Specific end use(s)
 SECTION VIII : Exposure controls/personal protection
 Control parameters
 Exposure controls
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9.  SECTION IX : Physical and chemical properties
 Information on basic physical and chemical properties
 Other information
 SECTION X : Stability and reactivity
 Reactivity
 Chemical stability
 Possibility of hazardous reactions
 Conditions to avoid
 Incompatible materials
 Hazardous decomposition products
 SECTION XI : Toxicological information
 Information on toxicological effects
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10.  SECTION XII : Ecological information
 Toxicity
 Persistence and degradability
 Bioaccumulative potential
 Mobility in soil
 Results of PBT (Persistent, Bioaccumulative and Toxic)
 Results of vPvB assessment (very Persistent and very Bioaccumulative)
 Other adverse effects
 SECTION XIII : Disposal considerations
 Waste treatment methods
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11.  SECTION XIV : Transport information
 UN (United Nations) number
 UN proper shipping name
 Transport hazard classes
 Packing group
 Environmental hazards
 Special precautions for user
 Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code
 SECTION XV : Regulatory information
 Safety, health and environmental regulations/legislation specific for the substance or mixture
 Chemical safety assessment
 SECTION XVI : Other information
 Date of the latest revision of the SDS
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12. HAZARD LABELS OF CHEMICALS 12

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14. PERSONAL PROTECTION EQUIPMENT
(PPE)
 Personal Protective Equipment (PPE) is any safety equipment workers wear to prevent
injury in the workplace when engineering and administrative controls fail to eliminate the
hazard.
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15.  COMMON TYPES OF PPE
 Head
 Eyes
 Face
 Hands
 Feet
 Body
 Hearing
 Respiratory
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16. REFERENCES
 https://en.wikipedia.org/wiki/Safety_data_sheet
 https://www.uregina.ca/hr/hsw/assets/docs/pdf/Laboratory-Safety/Material-Safety-
Data-Sheet.pdf
 https://www.slideshare.net/shijilkv/material-safety-data-sheet-49605019
 https://www.slideshare.net/parthihce/ppe-13652996
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