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LYMPHATICSYSTEM
•Lymphatic system is the
network of vessels through
which lymph drains from
the tissue to blood.
LYMPHATICSYSTEM…
•Lymphatic System=> Cells, tissues, and organs
that play a central role in the body’s defenses
against pathogens, toxins, waste , and unwanted
material.
•Lymphatic system consists of vessels (lymphatic)
filled with lymph connected to lymphatic organs.
FUNCTIONS
The lymphatic system has multiple interrelated functions ,
It is responsible for the removal of interstitial fluid from
tissues.
It absorbs and transports fatty acids and fats as chyle
from the digestive system .
It transports white blood cells to and from the lymph
node into bones.
COMPONENTSOFLYMPHATICSYSTEM
1) Lymph.
2) Lymph node.
3) Lymphatic vessels.
4) Lymphoid tissue.
5) Lymphatic organs.
1) LYMPH:-
• It is a clear , watery light yellowish fluid that
flows through the lymphatic system.
•
• Its composition is similar to plasma and
interstitial fluid with low protein content.
• It contains all types of leucocytes.
LPYMPHNODES:-
• Lymph node are the small glands that filter lymph,
• The clear fluid that circulates through the
lymphatic system.
• They become swollen in response to infection and
tumors.
CONT…
•Lymph nodes are oval or kidney shaped organs,
small in size 1-2 cm.
•
•It has an outer capsule of fibrous tissues.
• 500 to 700 bean-shaped lymph nodes scattered
throughout the body .
• The dark
lumps on the
membrane
are lymph
nodes.
STRUCTUREOF LYMPHNODE
• 1. Capsule.
• It is made up of connective tissue.
• 2. Hilum.
• Entrance for blood vessels and nerves.
• Efferent vessels leave from the hilum.
• 3.Cortex.
• Outer layer.
CONT…
• 4. Medulla.
• Inner layer.
• 5. Sinuses.
• Complex channels through which lymph circulates.
FUNCTIONOF LYMPHNODE
They are the major sites of B and T lymphocytes and
other white blood cells.
It acting as filters for foreign particles and cancer cells.
Filtration and purification of lymph.
CONT…
Site for lymphocyte proliferation.
Site for antibody production.
They do not have a detoxification function.
WHERELYMPHNODEAREPRESENT
• Lymph nodes are present
throughout the body and
are arranged in deep and
superficial groups.
MAJORLYMPHNODES
1) cervical
2) axillary
3) inguinal
4) mesenteric
1) CERVICAL LYMPH NODE
• located in neck area.
• filter lymph from head and
neck.
• Approximately 300 lymph
nodes are located in the
cervical region.
2.AXILLARYLYMPHNODES:-
• Located in armpits.
• Filter lymph from hand,
arm.
• Approximately 100 lymph
nodes are present in
axillary region.
3) INGUINALLYMPHNODES:-
•Located in groin
area.
•Filter lymph
from lower
extremities and
external genital
organs.
4.MESENTERICLYMPHNODES:-
•Located in abdominal
peritoneum.
•Aid in infection control
after abdominal surgery.
•Filter lymph from
abdominal cavity.
3)LYMPHATICVESSELS:-
lymphatic ducts
lymphatic trunks
lymphatic collecting vessels
lymphatic capillary
CONT…
blind ended vessels.
permeable to proteins even cells.
Themainfunction
• collect excess large particles and tissue fluid
4)LYMPHTISSUE:-
Located throughout the
body in addition to being
in the lymph nodes.
 Tonsils, spleen, and
thymus are examples of
lymphatic tissue.
5) LYMPHOIDORGANS:-
The immune system is made up
of organs that control the
production and maturation of
certain defense cells , the
lymphocytes.
1. Spleen.
2. Thymus.
3. Bone marrow.
4. Tonsils.
1. SPLEEN
• Spleen is the largest lymphoid organ.
• It is purplish in color.
• located in upper left abdominal quadrant between
9th-11th rib.
• between fundus of stomach and diaphragm.
SIZEOF SPLEEN
Its size varies in different
individuals usually about
12cm long,
 7cm wide,
 2.5 cm thick.
Its weighs about 200g.
STRUCTURE OF SPLEEN
capsule
covering of dense connective tissue.
hilum
 depression on medial surface .
nerves and arteries enter spleen, veins and lymphatic
vessel exit.
CONT…
• trabeculae
• extensions of capsule, form
partitions within the spleen .
• pulp
• tissue inside
• divided into red and white
pulp
FUNCTION OF SPLEEN:-
Produces leukocytes and antibodies.
 Destroys old erythrocytes or red blood cells.
Stores erythrocytes to release into blood stream if
excessive bleeding occurs.
 Destroys thrombocytes or platelets.
 Filters some metabolites and wastes from tissues.
2.THYMUSGLAND:-
• It is two-lobed organ.
• located in upper part of chest along trachea.
• Inferior to thyroid gland, posterior to sternum .
• Its weight is about 10g to 15g at birth.
• And at puberty is b/w 30g and 40g.
STRUCTUREOFTHYMUS:-
• The thymus consists of two
lobes joined by areolar
tissues.
• The lobes are enclosed by
fibrous capsule, dividing
them into lobules.
FUNCTION OFTHYMUS:-
• Maturation of immature lymphocytes in 2-3 days by
thymosin hormone.
• Proliferation of lymphocytes.
3.BONEMARROW:-
• Bone marrow is a semi – solid tissue which may be found
within the spongy or cancellous portion of bone.
• It composed of hematopoietic cells, marrow adipose
tissue and supportive stromal cells.
FUNCTION OFBONEMARROW:-
• The major function of
bone marrow is to
generate blood cells.
• That is responsible for the
production of blood cells.
4.TONSILS:-
• Multiple groups of large
lymphatic nodules.
• Location => mucous
membrane of the oral and
pharyngeal cavities.
TYPESOF TONSILS:-
1.Pharyngeal Tonsils:
Situated posterior to the nasal cavity, in the roof of the
nasopharynx.
2.Lingual Tonsils:
Located at the dorsal surface of the base of the tongue.
• Palatine Tonsils:
• There is one located on
each side of the oral
pharynx, in the back of
throat.
• Note:
• All tonsils provide a
defense against bacteria
entering the mouth.
PYER’SPATCHES
(Also known as aggregated lymph nodes.)
 Clusters of lymphoid tissue without a fibrous
capsule.
 Common in tonsils, small intestine, and
appendix.
Secrete antibodies in response to antigens in gut
tube, particularly ingested viruses and bacteria.
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