1. Here are the steps to name the molecule:
1) Identify the functional group (carbonyl group) which gives the compound the name of a ketone.
2) Name the parent chain (hexane) which contains the carbonyl group.
3) Number the parent chain starting from the end that gives the carbonyl carbon the lowest number.
4) Include the position of the carbonyl group as a prefix.
The IUPAC name is therefore: 3-hexanone
2. (a) 3-ethyloctane
(b) 1,4-dibromohexane
(c) 2,3,4-trimethylheptane
(d)
Basic concepts of organic chemistry such as structural formulas, different kinds of representation, types of isomerism, examples, alkanes, alkenes, alkynes etc.
Alkanes are organic compounds that consist entirely of single-bonded carbon and hydrogen atoms and lack any other functional groups. Alkanes have the general formula CnH2n+2 and can be subdivided into the following three groups: the linear straight-chain alkanes, branched alkanes, and cycloalkanes.
Basic concepts of organic chemistry such as structural formulas, different kinds of representation, types of isomerism, examples, alkanes, alkenes, alkynes etc.
Alkanes are organic compounds that consist entirely of single-bonded carbon and hydrogen atoms and lack any other functional groups. Alkanes have the general formula CnH2n+2 and can be subdivided into the following three groups: the linear straight-chain alkanes, branched alkanes, and cycloalkanes.
IUPAC nomenclature uses the longest continuous chain of carbon atoms to determine the basic root name of the compound. The root name is then modified due to the presence of different functional groups which replace hydrogen or carbon atoms in the parent structure.
IUPAC Nomenclature
IUPAC nomenclature uses the longest continuous chain of carbon atoms to determine the basic root name of the compound. The root name is then modified due to the presence of different functional groups which replace hydrogen or carbon atoms in the parent structure.
NOMENCLATURE OF ORGANIC COMPOUNDS BY -- KHUSH AHUJAKhushAhuja
In chemical nomenclature, the IUPAC nomenclature of organic chemistry is a method of naming organic chemical compounds as recommended[1] by the International Union of Pure and Applied Chemistry (IUPAC). It is published in the Nomenclature of Organic Chemistry (informally called the Blue Book). Ideally, every possible organic compound should have a name from which an unambiguous structural formula can be created. There is also an IUPAC nomenclature of inorganic chemistry.
To avoid long and tedious names in normal communication, the official IUPAC naming recommendations are not always followed in practice, except when it is necessary to give an unambiguous and absolute definition to a compound. IUPAC names can sometimes be simpler than older names, as with ethanol, instead of ethyl alcohol. For relatively simple molecules they can be more easily understood than non-systematic names, which must be learnt or looked over. However, the common or trivial name is often substantially shorter and clearer, and so preferred. These non-systematic names are often derived from an original source of the compound. In addition, very long names may be less clear than structural formula.
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This visual guide breaks down important metrics across four categories: Patient-Centered Metrics, Care Efficiency Metrics, Quality of Life Metrics, and Staff Metrics. Each section is designed to help healthcare professionals monitor and improve care delivery for patients facing serious illnesses. Understand how to implement these metrics in your palliative care practices for better outcomes and higher satisfaction levels.
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M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
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There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
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Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
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Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
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IUPAC Nomenclature of Organic Compounds Part-2.pptx
1. IUPAC Rules for Naming Alcohols
I. Select the longest chain to which the OH group is directly attached. Change “”e’’ of
the alkane corresponding to this chain to “ol”. This gives the basic name of the
alcohol.
2. Number the above chain so as to give the carbon bearing the OH group the lowest
possible number. Indicate the position of the OH group by using this number. The
numbering of the chain is done as above irrespective of whether a double or triple bond
is or is not a part of the parent chain.
3. Prefix the names of alkyl substituents with locator numbers as for alkanes. Thus
4. Molecules containing more than one OH group are referred to as diols (2-OH),
triols (3-OH), etc., in the IUPAC system
2. Write the IUPAC names of following compounds
IUPAC Rules for Naming Aldehydes
The IUPAC name for aldehydes (RCHO) is Alkanals. For naming an individual
aldehyde, the final “e” of the parent alkane is replaced with “al”. Since the functional
group CHO is always present at the end of the parent chain, it is not necessary to
designate its position. When other substituents are present, the parent chain including
the CHO group is numbered with carbon of CHO as number one.
3. IUPAC Rules for Naming Ketone
The IUPAC name of ketones (R—CO—R) is Alkanones and the functional
group —CO— is referred to as carbonyl group. The name of an individual
ketone is obtained by replacing the final “e” of the corresponding alkane
(containing same number of carbons) with “one”.
(I) Select the longest chain containing the -CO- group and write the basic
name after the parent alkane as shown above.
(2) Number the chain from the end that gives the -CO- group the lowest
possible number. This is the locator number of carbonyl group on the parent
chain.
(3) If the structure contains a double bond, name the ketone as Alkenone and
insert the position numbers.
(4) When there are present two carbonyl groups in a saturated parent chain the
compound is named as Alkanedione with position numbers prefixed to it.
4. IUPAC Rules for Naming Carboxylic acids
The IUPAC name of aliphatic carboxylic acids (RCOOH) is Alkanoic acids, while
the functional group COOH is referred to as carboxyl group.
(1) The longest chain containing COOH is selected and the basic name is derived
by changing ane of the corresponding alkane to oic acid.
(2) The chain is numbered starting with carboxyl carbon as one. Thus it is
unnecessary to give the number of COOH.
(3) A dicarboxylic acid is named as Alkanedioic acid with position numbers of
COOH groups prefixed with it.
5. IUPAC Rules for Naming Amines
• In the IUPAC system this class of compounds are named as Alkanamines. To
name a particular amine 'e, of the hydrocarbon name in deleted and the ending -
amine added.
• For naming Substituted amines, the longest chain bearing NH, group is
numbered and the position of the amino group prefixed to the basic name of the
amine. The names with locator numbers of the other substituents are described
as usual.
• A substituent on nitrogen atom is designated by capital N.
6. When present in molecules as a substituent, amino group is designated as amino.
Write the IUPAC names of following compounds
8. ▪ More complicated organic molecule sometimes is known
by its trivial name NOT IUPAC systematic name
Methyl 8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-
carboxylate
Cocaine
9.
10. IUPAC Rules for Naming Multifunctional compounds
1. Note the functional groups present in the given structure and then find out
from the priority Table given in next slide as to which of these stands nearest
to the top. This is the principal function and determines the family or class of
the compound.
2. When both a double and triple bond are present in a hydrocarbon, the chain is
numbered to give the multiple bonds (regardless of double or triple bond) the
lowest possible numbers. The locator numbers of double and triple bonds are
then inserted in the alkenyl name.
11. Nomenclature Priority for Citation as Principal Function
(IUPAC)
(Highest Priority is at the top)
Denoted by
Class Name Functional Group Prefix Suffix
Carboxylic acid —COOH - - -ole acid
Sulphonic acid - SO3H - -sulphonic acid
Acid halide -COX- - oyl chloride
Amide —CONH2 Amido- -amide
Nitrile -CN- Cyano- -nitrile
Aldehyde- —CHO Alkanoyl- -al
Ketone -CO- — Oxo- -one
Thiol —SH- Mercapto- -thiol
Amine —NH- Amino -amine
Alkene >C=C< - -ene
Alkyne —C≡C— - -yne
Alkane —C—C - -ane
Ether —OR Alkoxy -
Halides —F, —Cl, —Br, -I Halo- -
Nitro —NO2 Nitro- -
12. • When it has only substituents and no principal function.
The groups -F, - Cl, -Br, -I and –NO2, are always treated as substituents while naming
complex molecules. Thus a compound containing these functions has no principal
function.
13. For IUPAC nomenclature of substituted benzene compounds, the
substituent is placed as prefix to the word benzene as shown in
the following examples.
14. If benzene ring is disubstituted, the position of substituents is
defined by numbering the carbon atoms of the ring such that the
substituents are located at the lowest numbers possible.
In the trivial system of nomenclature the terms ortho (o), meta
(m) and para (p) are used as prefixes to indicate the relative
positions 1,2- ;1,3- and 1,4- respectively.
15.
16. Name the following compounds
● 1) CH2=CH-CH=CH2
But-1,3-diene
● 2) HOCH2(CH2)3CH2 COCH3 7-hydroxy hexane-2-one
● 3) CH3CH(CH3)CH2CH=CH2 4-methylpentene
● 4)COOHCH2CH2CH2CH2CH2COOH 1,7-diheptanoic acid
17. Starter questions
1. Name this molecule:
2. Draw these molecules:
(a) 3-ethyloctane
(b) 1,4-dibromohexane
(c) 2,3,4-trimethylheptane
(d) 3,4-diethyl-3,4,5-trimethyldecane