This document discusses using an adaptive neuro-fuzzy inference system (ANFIS) approach for automatic load frequency control of a four-area power system with multiple generation sources including renewable sources. The system consists of four equal areas, each with two thermal plants, a hydro plant, a wind plant, and an HVDC link. ANFIS combines the advantages of neural networks and fuzzy logic. The proposed ANFIS-PID controller is simulated and its performance is compared to a PID controller in response to a 1% load change in each area. Simulation results show the ANFIS-PID controller improves the system's dynamic response.