This document provides an introduction to partial differential equations (PDEs). It defines PDEs as equations involving an unknown function of two or more variables and certain of its partial derivatives. The document then classifies PDEs as linear, semilinear, quasilinear, or fully nonlinear based on how they depend on the derivatives of the unknown function. It lists many common and important PDEs as examples, including the heat equation, wave equation, Laplace's equation, and Euler's equations. Finally, it outlines strategies for studying PDEs, such as seeking explicit solutions, using functional analysis to prove existence of weak solutions, and developing theories to handle both linear and nonlinear PDEs.
Lesson 15: Exponential Growth and Decay (Section 021 slides)Matthew Leingang
Β
Many problems in nature are expressible in terms of a certain differential equation that has a solution in terms of exponential functions. We look at the equation in general and some fun applications, including radioactivity, cooling, and interest.
Partial Differential Equation plays an important role in our daily life.In mathematics, a partial differential equation (PDE) is a differential equation that contains unknown multivariable functions and their partial derivatives. PDEs are used to formulate problems involving functions of several variables, and are either solved by hand, or used to create a computer model. A special case is ordinary differential equations (ODEs), which deal with functions of a single variable and their derivatives.
PDEs can be used to describe a wide variety of phenomena such as sound, heat, diffusion, electrostatics, electrodynamics, fluid dynamics, elasticity, or quantum mechanics. These seemingly distinct physical phenomena can be formalised similarly in terms of PDEs. Just as ordinary differential equations often model one-dimensional dynamical systems, partial differential equations often model multidimensional systems. PDEs find their generalisation in stochastic partial differential equations.
Numerical solution of eigenvalues and applications 2SamsonAjibola
Β
This project aims at studying the methods of numerical solution of eigenvalue problems and their applications. An accurate mathematical method is needed to solve direct and inverse eigenvalue problems related to different applications such as engineering analysis and design, statistics, biology e.t.c. Eigenvalue problems are of immense interest and play a pivotal role not only in many fields of engineering but also in pure and applied mathematics, thus numerical methods are developed to solve eigenvalue problems. The primary objective of this work is to showcase these various eigenvalue algorithms such as QR algorithm, power method, Krylov subspace iteration (Lanczos and Arnoldi) and explain their effects and procedures in solving eigenvalue problems.
Lesson 15: Exponential Growth and Decay (Section 021 slides)Matthew Leingang
Β
Many problems in nature are expressible in terms of a certain differential equation that has a solution in terms of exponential functions. We look at the equation in general and some fun applications, including radioactivity, cooling, and interest.
Partial Differential Equation plays an important role in our daily life.In mathematics, a partial differential equation (PDE) is a differential equation that contains unknown multivariable functions and their partial derivatives. PDEs are used to formulate problems involving functions of several variables, and are either solved by hand, or used to create a computer model. A special case is ordinary differential equations (ODEs), which deal with functions of a single variable and their derivatives.
PDEs can be used to describe a wide variety of phenomena such as sound, heat, diffusion, electrostatics, electrodynamics, fluid dynamics, elasticity, or quantum mechanics. These seemingly distinct physical phenomena can be formalised similarly in terms of PDEs. Just as ordinary differential equations often model one-dimensional dynamical systems, partial differential equations often model multidimensional systems. PDEs find their generalisation in stochastic partial differential equations.
Numerical solution of eigenvalues and applications 2SamsonAjibola
Β
This project aims at studying the methods of numerical solution of eigenvalue problems and their applications. An accurate mathematical method is needed to solve direct and inverse eigenvalue problems related to different applications such as engineering analysis and design, statistics, biology e.t.c. Eigenvalue problems are of immense interest and play a pivotal role not only in many fields of engineering but also in pure and applied mathematics, thus numerical methods are developed to solve eigenvalue problems. The primary objective of this work is to showcase these various eigenvalue algorithms such as QR algorithm, power method, Krylov subspace iteration (Lanczos and Arnoldi) and explain their effects and procedures in solving eigenvalue problems.
We can defineΒ heteroscedasticityΒ as the condition in which the variance of the error term or the residual term in a regression model varies. As you can see in the above diagram, in the case of homoscedasticity, the data points are equally scattered while in the case of heteroscedasticity, the data points are not equally scattered.
Two Conditions:
1] Known Variance
2] Unknown Variance
We can defineΒ heteroscedasticityΒ as the condition in which the variance of the error term or the residual term in a regression model varies. As you can see in the above diagram, in the case of homoscedasticity, the data points are equally scattered while in the case of heteroscedasticity, the data points are not equally scattered.
Two Conditions:
1] Known Variance
2] Unknown Variance
FDM is an older method than FEM that requires less computational power but is also less accurate in some cases where higher-order accuracy is required. FEM permit to get a higher order of accuracy, but requires more computational power and is also more exigent on the quality of the mesh.29-Jun-2017
https://feaforall.com βΊ difference-bet...
What's the difference between FEM and FDM? - FEA for All
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Dynamical Systems Methods in Early-Universe CosmologiesIkjyot Singh Kohli
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Talk I gave at The Southern Ontario Numerical Analysis Day (SONAD): http://www.math.yorku.ca/sonad2014/ on General Relativity, Dynamical Systems, and Early-Universe Cosmologies.
Finite element method have many techniques that are used to design the structural elements like automobiles and building materials as well. we use different design software to get our simulated results at ansys, pro-e and matlab.we use these results for our real value problems.
IJERA (International journal of Engineering Research and Applications) is International online, ... peer reviewed journal. For more detail or submit your article, please visit www.ijera.com
IJERA (International journal of Engineering Research and Applications) is International online, ... peer reviewed journal. For more detail or submit your article, please visit www.ijera.com
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called βsmallβ because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's entangled aventures in wonderlandRichard Gill
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Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
1. INTRODUCTION of PARTIAL DIFFERENTIAL EQUATIONS
1. PARTIAL DIFFERENTIAL EQUATIONS
β’ A partial differential equations (PDE) is an equation involving an unknown
function of two or more variables and certain of its partial derivatives.
β’ Using the notation explained in Appendix A, we can write out symbolically a
typical PDE, as follows. Fix an integer π β₯ 1 and let π denote an open subset of
β π
.
DEFINITION. An expression of the form
πΉ(π· π
π’(π₯), π· πβ1
π’(π₯), β― , π·π’(π₯), π’(π₯), π₯) = 0 (π₯ππ) (1)
is called π kth
-order partial differential equation, where
πΉ: β π π
Γ β π πβ1
Γ β― β π
Γ β Γ π β β
is given, and
π’: π β β
is the unknown.
β’ We solve the PDE if we find all π’ verifying (1), possibly only among those
functions satisfying certain auxiliary boundary conditions on some part Ξof
ππ.
β’ By finding the solutions we mean, ideally, obtaining simple, explicit solutions
or failing that, deducing the existence and other properties of solutions.
DEFINITIONS.
i. The partial differential equation (1) is called linear if it has the form
οΏ½ π πΌ(π₯)π· πΌ
π’ = π(π₯)
|πΌ|β€π
for given functions π πΌ(πΌ| β€ π), f. This linear PDE is homogeneous if π β‘ 0.
ii. The PDE (1) is semilinear if it has the form
οΏ½ π πΌ(π₯)π· πΌ
π’ + π0(π· πβ1
π’, β― , π·π’, π’, π₯) = 0
|πΌ|=π
iii. The PDE (1) is quasilinear if it has the form
οΏ½ π πΌ(π· πβ1
π’, β― , π·π’, π’, π₯)π· πΌ
π’ + π0(π· πβ1
π’, β― , π·π’, π’, π₯) = 0
|πΌ|=π
Mohamad Tafrikan (moh.tafrikan@gmail.com) Page 1
2. iv. The PDE (1) is fully nonlinear if it depends nonlinearly upon the higest order
derivatives.
DEFINITION. An expression of the form
πΉ(π· π
π(π₯), π· πβ1
π(π₯), β― , π·π(π₯), π(π₯), π₯) = π (π₯ππ) (2)
is called a kth
-order system of partial differential equations, where
πΉ: β ππ π
Γ β ππ πβ1
Γ β― β ππ
Γ β π
Γ π β β π
is given, and
π: π β β π
, π = (π’1
, β― , π’ π)
is the unknown.
β’ Here we are supposing that the system comprises the same number π of scalar
equations as unknowns (π’1
, β― , π’ π).
β’ This is the most common circumstance, although other system may have fewer or
more equations than unknowns.
2. EXAMPLES
β’ There is no general theory known concerning the solvability of all partial
differential equations.
β’ Such a theory is extremely unlikely to exist, given the rich variety of physical,
geometric, probabilistic phenomena which can be modeled by PDE.
β’ Instead, research focuses on various particular partial differential equations that
important for applications within and outside of mathematics, with the hope that
insight from the origins of these PDE can give clues as to their solutions.
β’ Following is a list of many specific partial differential equations of interest in
current research.
β’ This listing is intended merely to familiarize the reader with the names and forms
of various famous PDE.
β’ To display most clearly the mathematical structure of the equations, we have
mostly relevant physical constants to unity.
β’ We will later discuss the origin and interpretation of many of these PDE.
β’ For each π₯ β π, where π is an open subset of β π
, and π‘ β₯ 0. Also
π·π’ = π·π₯ π’ = οΏ½π’ π₯1
, π’ π₯2
, β― , π’ π₯ π
οΏ½ denotes the gradient of π’ with respect to the
spatial variable π₯ = (π₯1, β― , π₯ π).
Mohamad Tafrikan (moh.tafrikan@gmail.com) Page 2
6. 1) Nonlinear equations are more difficult than linear equations, and indeed, the more
the nonlinearity affects the higher derivatives, the more difficult the PDE is.
2) Higher-order PDE are more difficult than lower-order PDE.
3) System are harder than single equations.
4) Partial differential equations entailing many independent variables are harder than
entailing few independent variables.
5) For most partial differential equations it is not possible to write out explicit
formulas for solutions.
4. OVERVIEW
This textbook is divided into three major Parts
PART I: Representation Formulas for Solutions
β’ Identify those important PDE for which in certain circumstances explicit or more-
or-less explicit formulas can be had for solutions.
β’ Chapter 2 is a detailed study of four exactly solvable PDE: the linear transport
equation, Laplaceβs equation, the heat equation, and the wave equation.
β’ Chapter 3 continues the theme of searching for explicit formulas, now for general
first-order nonlinear PDE.
β’ We stipulate that once the problem becomes βonlyβ the equation of integrating a
system of ODE.
β’ We introduce also the Hopf-Lax formula for Hamilton-Jacobi equations and the
Lax-Oleinik formula for scalar conservation laws.
β’ Chapter 4 is a grab bag of techniques for explicitly solving various linear and
nonlinear PDE.
PART II: Teori PDE Linear
β’ We abandon the search for explicit formulas and instead rely on functional
analysis and relatively easy βenergyβ estimates to prove existence of weak
solutions to various linear PDE.
β’ Chapter 5 is an introduction to Sobolev spaces, the proper setting for the study of
many linear and nonlinear PDE via energy methods.
β’ This is hard chapter, the real worth of which is only later revealed, and requires
some basic knowledge of Lebesgue measure theory.
Mohamad Tafrikan (moh.tafrikan@gmail.com) Page 6
7. β’ Chapter 6: we vastly generalize our knowledge of Laplaceβs equation to other
second-order elliptic equations.
β’ Chapter 7 expands the energy methods to a variety of linear PDE characterizing
evolutions in time.
PART III: Theory for Nonlinear PDE
β’ This section parallels for nonlinear PDE the development in Part II, but is far less
unified in its approach, as the various types of nonlinearity must be treated in
quite different ways.
β’ Chapter 8 commences the general study of nonlinear PDE with an extensive
discussion of the calculus of variations.
β’ Chapter 9, a gathering of assorted other techniques of use for nonlinear elliptic
and parabolic PDE.
β’ Chapter 10 is an introduction to the modern theory of Hamilton-Jacobi PDE, and
particular to the notion of βviscosity solutionsβ.
β’ We encounter also the connections with optimal control of ODE, through
dynamic programming.
β’ Chapter 11 is the discussion of conservation laws, now systems of conservation
laws.
5. PROBLEMS
1) Classify each of PDE in [2] as follows:
a) Is the PDE linear, semilinear, quassilinear, or fully nonlinear?
b) What is the order of the PDE?
2) Prove the Multinomial Theorem
(π₯1 + π₯2 + β― + π₯ π) π
= οΏ½ οΏ½
|πΌ|
πΌ
οΏ½ π₯ πΌ
|πΌ|=π
Where οΏ½|πΌ|
πΌ
οΏ½ =
|πΌ|!
πΌ!
, πΌ! = πΌ1! πΌ2! β― πΌ π!, and π₯ πΌ
= π₯1
πΌ1
β― π₯ π
πΌ π
. The sum is taken over all
multiindecs πΌ = (πΌ1, πΌ2, β― , πΌ π) with |πΌ| = π.
Multinomial Theorem is a natural extension of binomial theorem and proof gives a
good exercise for using the Principle of Mathematical Induction.
Theorem: Let P(n) be the proposition:
(π₯1 + π₯2 + β― + π₯ π) π
= οΏ½ οΏ½
|πΌ|
πΌ
οΏ½ π₯ πΌ
|πΌ|=π
Where οΏ½|πΌ|
πΌ
οΏ½ =
|πΌ|!
πΌ!
, πΌ! = πΌ1! πΌ2! β― πΌ π!, and π₯ πΌ
= π₯1
πΌ1
β― π₯ π
πΌ π
. The sum is taken over all
multiindecs πΌ = (πΌ1, πΌ2, β― , πΌ π) with |πΌ| = π. In another form
Mohamad Tafrikan (moh.tafrikan@gmail.com) Page 7