A explained presentation on fire and explosion hazard and their prevention in pharmaceutical and other chemical industry and transportation of flammable and explosive goods which could be helpful for pharmaceutical and other student who has hazard and there management in their syllabus
Module-I (12 Hours)
Development of safety movement: - Need for safety-safety and productivity-planning for safetyplanning
procedure-safety policy-formulation of safety policy-safety budget-role and
qualification of safety professional-safety committees-need, types and functions of committeessafety
organizations.
Module II (12 Hours)
Accident prevention: - Basic philosophy of accident prevention-nature and causes of accidentsaccident
proneness-cost of accidents-accident prevention methods-Domino theory-safety
education and training-training methods-motivation and communicating safety-personal
protective equipments.
Module III (12 Hours)
Safety management techniques: - Safety inspection-Safety sampling technique-Safety audit-
Safety survey-Incident recall technique-Job safety analysis-Damage control-Risk management.
Involvement in safety: - Role of management-role of supervisors-role of workmen- role of
unions-role of government
Module IV (12 Hours)
Occupational health and hygiene: - Functional units and activities of occupational health and
hygiene-types of industrial hazards-physical, chemical, mechanical, electrical, social, biological,
ergonomic and environmental hazards-factors impeding safety-house keeping-hearing
conservation programme
Module V (12 Hours)
Industrial fire protection: - Fire chemistry-classification of fires-fire prevention activities-fire
risks-fire load -contributing factors to industrial fires-fire detection-industrial fire protection
systems.
A explained presentation on fire and explosion hazard and their prevention in pharmaceutical and other chemical industry and transportation of flammable and explosive goods which could be helpful for pharmaceutical and other student who has hazard and there management in their syllabus
Module-I (12 Hours)
Development of safety movement: - Need for safety-safety and productivity-planning for safetyplanning
procedure-safety policy-formulation of safety policy-safety budget-role and
qualification of safety professional-safety committees-need, types and functions of committeessafety
organizations.
Module II (12 Hours)
Accident prevention: - Basic philosophy of accident prevention-nature and causes of accidentsaccident
proneness-cost of accidents-accident prevention methods-Domino theory-safety
education and training-training methods-motivation and communicating safety-personal
protective equipments.
Module III (12 Hours)
Safety management techniques: - Safety inspection-Safety sampling technique-Safety audit-
Safety survey-Incident recall technique-Job safety analysis-Damage control-Risk management.
Involvement in safety: - Role of management-role of supervisors-role of workmen- role of
unions-role of government
Module IV (12 Hours)
Occupational health and hygiene: - Functional units and activities of occupational health and
hygiene-types of industrial hazards-physical, chemical, mechanical, electrical, social, biological,
ergonomic and environmental hazards-factors impeding safety-house keeping-hearing
conservation programme
Module V (12 Hours)
Industrial fire protection: - Fire chemistry-classification of fires-fire prevention activities-fire
risks-fire load -contributing factors to industrial fires-fire detection-industrial fire protection
systems.
Every workplace safety program has a foundation. These key elements construct the framework for a solid understanding on how safety works and it empowers and engages everyone on different levels. Once this fundamental understand is achieved, it is easier to develop the policy, written programs, and standard operating procedures to move the process forward.
Every workplace safety program has a foundation. These key elements construct the framework for a solid understanding on how safety works and it empowers and engages everyone on different levels. Once this fundamental understand is achieved, it is easier to develop the policy, written programs, and standard operating procedures to move the process forward.
Experience and resourcesful Pharmacist with years of expertise in prescription review, medication processing and dispensing. Skilled in effectively coordinating with pharmacy staff to prioritize urgent request while ensuring accuracy, safety and maintaining patient information confidentiality. A proficient communicator, adept at collaborating closely with staff, patients, administrator and health care professionals. Currently seeking a challenging position within a progressive organization that allows me to contribute my skills toward achieving objectives while continuously developing and enhancing my professional abilities.
Do you want to be a hero? Industrial hygienists do it everyday in the workplace. They protect workers from health hazards that include a variety of dust, mists, fumes, gases, and vapors by testing the atmosphere in which they breath and evaluate the exposure against standards and guidelines. They are interested in examining all of the potential toxins in the air, on building surfaces, those that can be ingested or a combination thereof. It's not an easy task. Industrial hygienist need to talk with many stakeholders in finance, engineering, human resources, public policy, medicine, law, etc. The idea is to identify the potential health hazards that may cause harm to workers, unsuspecting public, and the environment. Many of these hazards involve chemicals, biological and physical agents, radiological exposure, human factors and ergonomics, indoor air quality, toxicology and epidemiology, handling and storage, transportation, research and development, and many other considerations. So if you want to be a hero, contact your local section of the American Industrial Hygiene Association. They can provide the information that you will need for a career pathway from academia to senior business professional.
SAFETY METHODS IN PHARMACEUTICAL INDUSTRYssuser5a17b2
SAFETY METHODS IN PHARMACEUTICAL INDUSTRY
(a)
(b)
Mechanical, chemical and fire hazards problems.
Inflammable gases and dusts.
Please provide feed back
I Have completed this assignment in 5-6 hours . I am helping others student as well.
Identification of occupational diseases, health risk, hazard and injuries amo...eSAT Journals
Abstract
Thermal power plant uses coal as fuel for their working. Coal after burning leaves ash. Disposal of this ash is also one important task. Ash comes in contact with open environment and has adverse effects on health of human being. Due to these various health problems like skin diseases, breathing problem etc. are started in man working under those premises. Some other elements like boiler, turbine, generator, material handling are those elements due to which hazards and accidents take place while operation and maintenance of these. This work focuses on identification of various Occupational diseases and injuries, health risks associated with the man power working in thermal power plant. This data were collected by questionnaires and personnel interview of the workers working in different section of the thermal power plant like boiler section, turbine & generator section, coal & ash handling plant, hydrogen plant etc. Analysis is done in terms of different variables, such as age, skills experience, type of injuries and type of diseases. Results are shown in the form graph and chart. The results indicate a remarkable and visible impact on health of workers during operation and maintenance.
Key Words: Occupational hazards and Diseases, health risk, Injuries, Questionnaires, Personnel interview.
Bioassay (commonly used shorthand for biological assay), or biological standardization is a type of scientific experiment. A bioassay involves the use of a live animal (in vivo) or tissue (in vitro) to determine the biological activity of a substance, such as a hormone or drug. Bioassays are typically conducted to measure the effects of a substance on a living organism and are essential in the development of new drugs and in monitoring environmental pollutants. Both are procedures by which the potency or the nature of a substance is estimated by studying its effects on living matter. A bioassay can also be used to determine the concentration of a particular constitution of a mixture.
Dissolution is pharmaceutically defined as the rate of mass transfer from a solid
surface into the dissolution medium or solvent under standardized conditions of
liquid/solid interface, temperature and solvent composition.
OFFICIAL DISSOLUTION APPARATUS
USP 30 classification
1. Rotating Basket (Ph.Eur./BP/JP)
2. Paddle (Ph.Eur./BP/JP)
3. Reciprocating Cylinder (Ph.Eur.)
4. Flow Through Cell (Ph.Eur./BP/JP)
5. Paddle Over Disk (Ph.Eur.)
6. Rotating Cylinder (Ph.Eur.)
7. Reciprocating Holder
Unveiling the Secrets How Does Generative AI Work.pdfSam H
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Grote partijen zijn al een tijdje onderweg met retail media. Ondertussen worden in dit domein ook de kansen zichtbaar voor andere spelers in de markt. Maar met die kansen ontstaan ook vragen: Zelf retail media worden of erop adverteren? In welke fase van de funnel past het en hoe integreer je het in een mediaplan? Wat is nu precies het verschil met marketplaces en Programmatic ads? In dit half uur beslechten we de dilemma's en krijg je antwoorden op wanneer het voor jou tijd is om de volgende stap te zetten.
Personal Brand Statement:
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[Note: This is a partial preview. To download this presentation, visit:
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Sustainability has become an increasingly critical topic as the world recognizes the need to protect our planet and its resources for future generations. Sustainability means meeting our current needs without compromising the ability of future generations to meet theirs. It involves long-term planning and consideration of the consequences of our actions. The goal is to create strategies that ensure the long-term viability of People, Planet, and Profit.
Leading companies such as Nike, Toyota, and Siemens are prioritizing sustainable innovation in their business models, setting an example for others to follow. In this Sustainability training presentation, you will learn key concepts, principles, and practices of sustainability applicable across industries. This training aims to create awareness and educate employees, senior executives, consultants, and other key stakeholders, including investors, policymakers, and supply chain partners, on the importance and implementation of sustainability.
LEARNING OBJECTIVES
1. Develop a comprehensive understanding of the fundamental principles and concepts that form the foundation of sustainability within corporate environments.
2. Explore the sustainability implementation model, focusing on effective measures and reporting strategies to track and communicate sustainability efforts.
3. Identify and define best practices and critical success factors essential for achieving sustainability goals within organizations.
CONTENTS
1. Introduction and Key Concepts of Sustainability
2. Principles and Practices of Sustainability
3. Measures and Reporting in Sustainability
4. Sustainability Implementation & Best Practices
To download the complete presentation, visit: https://www.oeconsulting.com.sg/training-presentations
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Retail media wordt gezien als het nieuwe advertising-medium en ook mediabureaus richten massaal retail media-afdelingen op. Merken die niet in de betreffende winkel liggen staan ook nog niet in de rij om op de retail media netwerken te adverteren. Marvin belicht de uitdagingen die er zijn om echt aansluiting te vinden op die markt van non-endemic advertising.
As a business owner in Delaware, staying on top of your tax obligations is paramount, especially with the annual deadline for Delaware Franchise Tax looming on March 1. One such obligation is the annual Delaware Franchise Tax, which serves as a crucial requirement for maintaining your company’s legal standing within the state. While the prospect of handling tax matters may seem daunting, rest assured that the process can be straightforward with the right guidance. In this comprehensive guide, we’ll walk you through the steps of filing your Delaware Franchise Tax and provide insights to help you navigate the process effectively.
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Exploring Patterns of Connection with Social Dreaming
Industrial hazard pdf
1. Compiled by-Shamon Ahmad,, M.Pharma (Q.A) Chandigarh Group of Colleges, Landra, Mohali(Punjab
India)email-shmmon@gmail.com 28/12/2012
INDUSTRIAL HAZARDS
INTRODUCTION
Hazard is a term associated with a substance that is likelihood to cause an injury in a given
environment or situation.
“Industrial hazard may be defined as any condition/substance produced by industries that may cause
injury or death to personnel or loss of product or property”.
Safety in simple terms means freedom from the occurrence of risk or injury or loss. Industrial safety
refers to the protection of workers from the danger of industrial accidents.
Accidents:
Human factor is the contributing cause of accidents in most situations.For people who are likely to have
accidents, the treatment is divided into three main categories
Medical assistance- in 13 percent cases
Personality readjustment- in 22 percent cases
Operating defects- the remaining 65 percent cases
Accident reduction:
Accident proneness is acceptable to a certain extent, it does not mean that nothing can be done to
reduce the number of accidents
Accidents can be reduced by two approaches
Actuarial approach- It involves studying the statistics to determine accidents based on actual data .
The factors related to the accident frequency should be identified. The violations of safety rules must
be clearly identified.
Safety educational campaign -Safety education must be conducted by management to the employee
groups.
Types of Industrial Hazards
1. Chemical hazards
2. Physical hazards
3. Biological hazards
CHEMICAL HAZARD;
Chemical hazards are posed by toxic germicides (e.g., formaldehyde and glutaraldehyde) and
sterilizing gases (i.e., ethylene oxide). Reaction Gases(Carbon mono oxide,so2). Whenever possible,
less hazardous agents should be selected (e.g., alcohols, ammonium compounds). Sterilization of raw
materials and equipment may be performed by high-pressure steam or toxic gases (i.e., diluted
2. ethylene oxide gas mixtures) . Sterilization vessels can be located in separate areas with remote
instrument and control systems.
Workers should be trained on standard operating instructions, safe work practices and appropriate
emergency response. Gas sterilization chambers should be fully evacuated(khali,space) under
vacuum and purged with air to minimize fugitive workplace emissions before sterilized goods are
removed. Gas emissions from sterilization chambers can be vented to air control devices (e.g., carbon
adsorption or catalytic converters) to reduce atmospheric emissions. Occupational hygiene
monitoring measures worker exposures to chemical germicides and sterilizing gases, helping to
assess the adequacy of control measures. Safety hazards involve high-pressure steam and hot water,
moving machine parts in washing, filling, capping and packaging equipment, high noise levels and
repetitive manual tasks.
CLEANING AND MAINTENANCE ACTIVITIES
Non-routine tasks may occur when cleaning, repairing and maintaining equipment, utilities and
workplaces. Although unique hazards may arise during non-routine tasks, recurring health and safety
concerns are encountered. Workplace and equipment surfaces may be contaminated by hazardous
materials and drug substances, requiring them to be cleaned before unprotected workers conduct
servicing or maintenance work. Cleaning is performed by washing or wiping liquids and sweeping or
vacuuming dusts. Dry sweeping and blowing solids with compressed air are not recommended, since
they create high worker exposures to airborne dusts. Wet mopping and vacuuming reduce worker
exposures to dusts during cleaning activities. Vacuum cleaners with HEPA filters may be needed
when cleaning hazardous substances and high-potency drugs. Explosion-proof equipment and
conductive materials may be required in vacuum systems for explosive dusts. Eyewashes and safety
showers and PPE reduce the effect of workers’ accidental contact with corrosive and irritating
detergents and cleaning liquids.
Hazardous mechanical, electrical, pneumatic or thermal energy may need to be released or controlled
before equipment and utilities are serviced, repaired or maintained. Contract workers may perform
special production or engineering tasks in pharmaceutical plants without adequate training on safety
precautions. Careful supervision of contract workers is important, so they do not violate safety rules
or perform work that creates a fire, explosion or other serious health and safety hazards. Special
contractor safety programmes are required when working with highly hazardous materials (e.g.,
toxic, reactive, flammable or explosive) and processes (e.g., exothermic or high pressure) in bulk
pharmaceutical and dosage-form manufacturing facilities.
GENERAL HEALTH AND SAFETY HAZARDS
Ergonomics and material handling
The materials shipped, stored, handled, processed and packaged in the pharmaceutical industry range
from large quantities of raw materials to small packages containing pharmaceutical products. Raw
materials for bulk chemical production are shipped in bulk containers (e.g., tank trucks, rail cars),
3. metal and fibre drums, reinforced paper and plastic bags. Pharmaceutical production uses smaller
quantities of raw materials due to the reduced scale of the operations. Material-handling devices (e.g.,
fork-lift trucks, pallet lifts, vacuum hoists and drum jacks) assist material handling during
warehousing and production operations. Heavy manual work may create ergonomic risks when
moving materials and equipment if mechanical devices are not available. Good industrial engineering
and facility management practices reduce injuries from material handling by improving the design
and features of equipment and the workplace and decreasing the size and weight of containers (Cole
1990). Engineering control measures (e.g., ergonomic design of tools, materials and equipment) and
administrative practices (e.g., rotating workers, providing worker training) reduce the risks of
cumulative trauma injuries during highly repetitive production and packaging operations.
Machine guarding and control of hazardous energy
Unguarded moving machine parts in pharmaceutical manufacturing and packaging equipment create
mechanical hazards. Exposed “crush and nip points” in open equipment may seriously injure
workers. Mechanical hazards are exacerbated by the large numbers and different designs of
equipment, crowded workplace conditions and frequent interactions between workers and equipment.
Interlocked guards, control switches, emergency stop devices and operator training are important
means of reducing mechanical hazards. Loose hair, long-sleeved clothing, jewellery or other objects
may become trapped in equipment. Routine inspection and repair activities identify and control
mechanical hazards during production and packaging operations. Hazardous electrical, pneumatic
and thermal energy must be released or controlled before working on active equipment and utilities.
Workers are protected from sources of hazardous energy by implementing lockout/tagout procedures.
Noise exposures
High sound levels may be generated by manufacturing equipment and utilities (e.g., compressed air,
vacuum sources and ventilation systems). Due to the enclosed design of pharmaceutical workplace
modules, workers are often located close to machines during manufacturing and packaging
operations. Workers observe and interact with production and packaging equipment, thereby
increasing their exposure to noise. Engineering methods reduce sound levels by modifying, enclosing
and dampening noise sources. Employee rotation and use of hearing-protective devices (e.g., ear
muffs and plugs) reduce workers’ exposure to high noise levels. Comprehensive hearing conservation
programmes identify noise sources, reduce workplace sound levels, and train workers on the hazards
of noise exposure and proper use of hearing-protective devices. Noise monitoring and medical
surveillance (i.e., audiometry) assess worker exposures to noise and their resulting loss of hearing.
This helps to identify noise problems and evaluate the adequacy of corrective measures.
Solvent vapour and potent compound exposures
Special concerns may arise when workers are exposed to toxic solvent vapours and potent drugs as
airborne dusts. Worker exposures to solvent vapours and potent compounds may occur during
various manufacturing operations, which need to be identified, evaluated and controlled to ensure
that workers are protected. Engineering controls are the preferred means of controlling these
exposures, due to their inherent effectiveness and reliability (Cole 1990; Naumann et al. 1996).
Enclosed process equipment and material handling systems prevent worker exposures, while LEV
4. and PPE supplement these measures. Increased facility and process containment is needed for
controlling highly toxic solvents (e.g., benzene, chlorinated hydrocarbons, ketones) and potent
compounds. Positive-pressure respirators (e.g., powered-air purifying and supplied-air) and PPE are
needed when highly toxic solvents and potent compounds are handled and processed. Special
concerns are posed by operations where high levels of solvent vapours (e.g., compounding,
granulating and tablet coating) and dusts (e.g., drying, milling and blending) are generated. Locker
and shower rooms, decontamination practices and good sanitary practices (e.g., washing and
showering) are necessary to prevent or minimize the effects of worker exposures inside and outside
the workplace.
Process safety management
Process safety programmes are implemented in the pharmaceutical industry due to the complex
chemistry, hazardous materials and operations in bulk chemical manufacturing (Crowl and Louvar
1990). Highly hazardous materials and processes may be employed in multi-step organic synthesis
reactions to produce the desired drug substance. The thermodynamics and kinetics of these chemical
reactions must be evaluated, since they may involve highly toxic and reactive materials, lachrymators
and flammable or explosive compounds.
Process safety management involves conducting physical hazard testing of materials and reactions,
performing hazard analysis studies to review the process chemistry and engineering practices,
examining preventive maintenance and mechanical integrity of the process equipment and utilities,
implementing worker training and developing operating instructions and emergency response
procedures. Special engineering features for process safety include selecting proper pressure-rated
vessels, installing isolation and suppression systems, and providing pressure relief venting with catch
tanks. Process safety management practices are similar in the pharmaceutical and chemical industries
when manufacturing bulk pharmaceuticals as speciality organic chemicals (Crowl and Louvar 1990;
Kroschwitz 1992).
Environmental Issues
The different pharmaceutical manufacturing processes each have their own environmental issues, as
discussed below.
INDUSTRIAL HAZARDS :
HAZARD
It means anything with potential for producing an accident.
It is a term associated with a substance that is likelihood to cause an injury in a given environment or
situation.
Industrial hazard may be defined as any condition produced by industries that may cause injury or
death to personnel or loss of product or property.
Industrial hazards are threats to people and life-support systems that arise from the mass production
of goods and services.
5. Toxic and corrosive chemicals, fire, explosions and personnel falling into accidents are the major
health and safety hazards encountered in the operations of chemical and pharmaceutical related
industries.
ROUTES OF INDUSTRIAL HAZARDS ENTRY INTO THE BODY
There are three main routes by which hazardous chemicals entered the body:
Absorption through the respiratory tract through inhalation.
Absorption or injection through the skin or eyes.
Absorption through the digestive tract.
HAZARD CATEGORIES
Chemical Hazards
Gas Hazards
Dust Explosion
Fire and Explosion Hazards
Biological Hazards
CHEMICAL HAZARDS
Some chemicals have the potential to cause fires and explosions and other serious accidents.
Chemical exposure may cause or contribute to many serious health effects such as heart diseases,
central nervous system damage, kidney and lung damage, sterility, cancer, burns, and rashes.
Chemicals may be found in solid, liquid, aerosol, or gas and vapor form.
The degree of danger varies according to the form of the chemical and the factors like,
Its physical properties(ph,Acid,flammable),
Its toxicity,(poision)
The way it is used(eye,respiratory)
The environment in which it is encountered(SO2.CH4)
Routes of entry - Inhalation, Ingestion, skin absorption.
Chemical agents can be classified into1) Metals - Lead, TEL, As, Hg, Cd, Ni , Co
2) Aromatic Hydrocarbons - Benzene, Toluene, phenol
3) Aliphatic Hydrocarbons - Methyl alcohol
4) Gases * Simple asphyxiants : N2, CH4, CO2
* Chemical asphyxiants : CO, H2S, HCN
* Irritant gases: Ammonia, SO2, Cl2
* Systemic poison: CS2
Not all forms of a chemical pose a health hazard. For example, a lead pipe is not a significant
health hazard. However, the lead can become a human health hazard if the pipe is welded, producing
a lead dust or fumes. The dust or fumes can become inhaled, or it can leach into water and be
ingested.
A chemical may be hazardous even in solid form. For example, individuals who are sensitized
to nickel may develop dermatitis from skin contact with the metal.
6. Some solids are not a hazard alone but become hazardous when they come into contact with
other chemicals.
MANAGEMENT OF OVER-EXPOSURE TO CHEMICALS
1. Removal from Exposure:
Prompt removal of the person from the exposure site is the first step.
Air respirators and lifelines are first aid.
2. Resuscitation:
Resuscitation means restoration of life of one who is apparently dead (collapsed or shocked).
Further supportive care should be provided as with any other medical emergency.
3. Decontamination:
A victim whose skin or clothing has been contaminated requires immediate removal of garments and
shoes. Then body showering with soap and water, including attention to the fingernails and
scalp(head, sir) is advised.
4. Symptomatic Treatment:
Acute over-exposure may result in a variety of signs and symptoms that require general supportive
medical management regardless of the specific agent. Examples include the control of convulsive
seizures, treatment of bronchospasm etc.
TLV CONCEPT
Threshold Limit Value-Time Weighted Average (TLV-TWA):
Time-weighted average concentration for a normal 8-hour working day and a 40-hour working week,
to which nearly all workers may be repeatedly exposed day after day, without adverse effect.
Threshold Limit Value-Short Term Exposure Limit (TLV-STEL):
It is defined as a 15-minute, time-weighted average which should not be exceeded at any time during
a working day, even if the 8-hour time-weighted average is within the TLV.
The workers should not be exposed to the substances more than these limits.
TLVs are only guidelines and are not intended as absolute boundaries between safe and dangerous
concentrations.
Every occupational health professional should have a copy of the current TLVs.
HAZARDOUS GASES:
Several volatile and flammable liquids are employed in chemical industries.
These liquids get vaporized when exposed to at or above room temperature causing air pollution.
The vapour gets ignited causing fire accidents and explosions. Further, they tend to spread rapidly
into the surrounding area.
Result in loss of life and property. Hence, storage and handling of these hazardous gases need special
attention to avoid hazards.
7. Combustible Gases
Explosion hazard.
Must maintain below lower explosive limit.
Toxic Gases
Hazardous to human health.
Employee exposure must be limited.
Oxygen Displacing Gases
Indirect human health hazard.
Deficiency of breathing oxygen.
HYDROGEN SULFIDE
H2S in Air
Toxic Symptoms
1 ppm
Odor detected, irritation of respiratory tract
10 ppm
Allowable for 8 hours exposure
20 ppm
Protective equipment is necessary
100 ppm
Smell killed in 5 to 15 minutes.
May burn eyes and throat; coughing
500 ppm
Respiratory disturbances in 2 to 15 minutes.
Coughing, collapse & unconsciousness
1,000 ppm
immediate unconsciousness,
Brain damage may result unless rescued promptly.
Death in 3 to 5minutes.
OXYGEN DEFICIENCY:
Oxygen Symptoms Developed,
20.9%
Normal oxygen concentration in air
15 - 19%
Decreased ability to work strenuously
12 - 14%
Respiration increases in exertion, pulse up, impaired
coordination,
perception & judgment
8 - 10%
Mental failure, fainting, unconsciousness, blueness of lips, nausea &
vomiting
6 - 8%
8 min, 100% fatal; 6min, 50% fatal; 4 - 5min, recovery with treatment
4 - 6%
Coma in 40 seconds, convulsions, respiration ceases, death.
HAZARDOUS GASES MANAGEMENT:
8. Compressed gases are filled in cylinders and transported to the place of use. The important
precautions to be followed are given below:
1. Cylinders should not be permitted to strike(marna,hit) against each other.
2. Special and standard tools should be used on valves. Normally these are provided by
manufacturers.
4. Cylinders should be protected against extrem of weather, particularly against excessive rise in the
temperature(than cylinder fat jyega).
5. Cylinders (received) should bear a conspicuous standard label indicating the kind of gas. The
colour of the label shows whether gas is inflammable, corrosive or inert.
6. Full cylinders should be separated from empty cylinders.
GAS SENSOR PLACEMENT
Place sensors close to possible gas source.
Place sensors in areas where gas might accumulate.
Place toxic gas and oxygen deficiency sensors in the “breathing zone”.
Consider accessibility and maintenance issues.
GAS WEIGHT IN RELATION TO AIR
Carbon Monoxide
Slightly Lighter
Ethylene
Slightly Lighter
Ammonia
Lighter(means its effect upper side/near flore)
Methane
Lighter
Hydrogen
Lighter
Butane
Heavier
Chlorine
Heavier(it nt simply out to room)
Heptane
Heavier
Ethane
Slightly Heavier
DUSTS EXPLOSION
Dust means, if the maximum particle size of the solids in the mixture is 500 mm.
Dust explosion is a rapid combustion of a dust cloud. During the process, heat and reaction products
are evolved. The required oxygen for combustion is mostly supplied by air.
If iron or stone pieces get into the disintegrator or grinding mill, sparks are emitted, which may bring
about explosion with some easily combustible materials.
It has been found that in pharmaceutical industry, dust of starch and dextrin besides organic
substances are extremely hazardous.
FACTORS IMPACTING A DUST EXPLOSION(dhmaka,visfot)
1.
2.
3.
4.
Particle size
Chemical properties of a dust
Moisture content
Cloud dispersion
COMBUSTION PRINCIPLES
9. Fire is a rapid oxidation process with the evolution of light and heat in varying intensities.
2C + O2
2CO
SO2+2H2O
H2SO4
DUSTS MANAGEMENT:
1. Avoiding the development of explosive mixtures: Dust should not be accumulated at a
place. Removed from the site as soon as it forms.
2. Replacing the atmospheric oxygen by inert gas or using inert dust: This process is also
known as inerting. Explosion dusts can be changed into mixture by the addition of inert dust
such as rock salt and sodium sulphate, so that dust is diluted to a level less than its lower limit
of explosive range.
3. Preventing the occurrence of effective ignition source: Some of the ignition sources are
welding, smoking, cutting, and mechanically generated sparks and the resulting hot sources.
The premises must be kept very clean, eliminating all sources of ignition.
CONTROL OF DUST EXPLOSION
In pharmaceutical industry, dust is controlled by three methods.
Filtration
Inertial separation
Electrostatic precipitation
FIRE AND EXPLOSION HAZARDS
Spontaneous combustion and non-explosion proof electrical equipment is the potential ignition
source.
The severity of the burns depends on the intensity of the fire and the explosion time.
Fire occurs in the industry more frequently than explosions and toxic release, although the
consequences in terms of loss of life are generally less. So, fire might be less hazardous.
CONTROL OF FIRE AND EXPLOSION
1. Careful plant layout and judicious(specific) choice of constructional materials can reduce fire
and explosion hazards.
2. Fire resistance(rokne wale) brick-walls can limit the effects of an explosion.
3. The roof is designed to lift easily under an explosive force.
4. Possible sources of fire are reduced by eliminating the unnecessary ignition(jalne wale)
sources such as flames, spark, smoking, welding etc.
5. The installation of sufficient fire alarms, temperature alarms, fire-fighting equipment and
sprinkler systems must be specified.
Building Construction:
Building should be constructed such that fire can’t be separated from one building to another. When
combustible construction is necessry, firewall cutoffs should be provided.
10. Exit Points:
The exit points of adequate capacity should be provided so as to enable the employees to reach a
place of safety outside the building, in case of fire.
Fire Alarm Equipment:
Fire alarm systems are placed in conspicuous locations in all parts of the plant for promptly notifying
the fire brigade and for exit of employees.
Sprinkler Systems:
Automatic sprinkler is a device for discharging water automatically on a fire.
Safety and Fire Protection Organization:
A central committee composed of the plant manager as permanent chairman and safety and fire
protection supervisor as permanent secretary.
Fire Extinguishers:
Fire extinguishers are installed inside hose. These are designed for extinguishing the incipient fires.
The incipient fires are divided into three categories,
Class A fires: These fires are originated from ordinary combustible(jalne wale) materials. These fires
are controlled using water which produces quenching and cooling effects.
Class B fires: These fires are originated from oil’s, greases, flammable liquids etc. The extinguishing
agent should produce a blanketing or smoothening effect.
Class C fires: These fires are originated in electrical equipment. The extinguishing agent produces a
non-conducting property.
BIOLOGICAL HAZARD
This can include medical waste or samples of a microorganism, virus or toxin that can impact human
health.It can also include substances harmful to animals.
Biological hazards cause a lot number of diseases like,
Brucellosis: it usually occurs in dairy farm workers. Symptoms - fever, arthritis, and enlarged spleen
etc.,
Byssinosis: It usually found in textile industries workers due to inhalation of the cotton fibre, dust
over long period of time. Symptoms - Cough breathlessness, slight fever and bronchitis.
Others are baggosis and locomotor disorder.