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INDUSTRIAL HAZARDS AND
  PREVENTION SYSTEMS

  P. Raja abhilash. M.Pharm. (Ph.D.)
          Assistant professor
      S.R. college of phramacy.
CONTENTS
   INTRODUCTION
   WHAT ARE INDUSTRIAL HAZARDS?
   GENERAL HAZARDS IN INDUSTRIES
   a) Fire accidents
   b) Mechanical
   c) Electrical
   d) Chemical and Pharmaceutical
   E) Dust explosion
   IMAGES FOR UNDERSTANDING BETTER INDUSTRIAL
    SAFETY
   CONCLUSION
   REFERENCES.
INTRODUCTION
HAZARD is a situation that posses a level of threat to life,
  health, property or environment

INDUSTRIAL HAZARD may be defined as any condition
  produced by industries that may cause injury or death to
  personnel or loss of product or property.

SAFETY in simple terms means freedom from the occurrence of
  risk or injury or loss .

INDUSTRIAL SAFETY refers to the protection of workers from
  the danger of industrial accidents .
WHAT ARE INDUSTRIAL
            HAZARDS?
 Physical --noise,vibration, heat, cold,pressure,
    radiation, fibres,…
 Chemical – flammable/explosive materials,
  toxics, sensitising agents.
 Biological – dust , pathogens
 Psyhological – work place practices &
  systems, payment systems
GENERAL HAZARDS IN
         INDUSTRIES
 FIRE HAZARDS
 MECHANICAL HAZARDS
 ELECTRICAL HAZARDS
 CHEMICAL HAZARDS
 PHARMACEUTICAL HAZARDS
 RADIATION HAZARDS
 DUST EXPLOSION
FIRE HAZARDS
   Fire is an exothermic chemical reaction between oxygen and
    fuel.
   Combustion
          Slow combustion eg: cotton waste burning
          Rapid combustion eg: petroleum product
          Spontaneous combustion eg: paint, scrap

   The effect of fire on people take the form of skin burns .
   Fire can take several different forms including jet fires ,pool
    fires and boiling liquid expanding vapour explosion.
SOURCES OF FIRE HAZARDS
   Hot surfaces
   Combustible and flammable liquids
   Heat utilization equipments (over heating)
   Chemical process equipments
   Lightening
   Gas cylinders
   Ovens and furnaces
   Reactor
   Welding and cutting
   Spark from metal to metal contact
   Carelessness
TYPES OF FIRE
Steps to be taken
  Don’t panic
 Raise the alarm
 Evacuate the premises
 Turn off the gas supply
 Attack the fire with extinguisher
 Or vacate the place
In case of fire safe methods to be followed
 Stair cases only to be used for evacuation
 Exit doors should be closed after getting out
 Go down the stair case to the ground
 Walk do not run
 Encounter heavy smoke crawl on the floor, do not talk, cover the
   nose and mouth with a wet cloth
FIRE EXTINGUISHERS
FIRE EXTINGUISHERS TABLE
CONTROL OF FIRE ACCIDENTS
 Fire protection is an important part of good
  house keeping.
 Prohibition of smoking in manufacturing area
 Oxygen present in atmosphere may be reduced
  by dilution with gases as Nitrogen, Carbon
  dioxide..
 Identification and control of ignition sources in
  areas where flammable chemicals are
  stored/handled/transferred.
 Elimination of ignition sources.
 Careful plant layout.
 Fire resistance brick walls or reinforced
  concrete walls.
 Suitable exit facility to be provided.
 Adequate ventilation facility.
 Sprinkler with reliable water supply.
 Installation of sufficient fire alarms .
MECHANICAL HAZARDS
Occurs due to:
 Large number of equipments
 Crowded work place conditions
 Frequent interaction between worker and equipment
 Insecurely fixed machines
 Worn and teared parts
 Failure of SOP
 Dangerous Parts
 Negligence
 Improper maintenance of equipment


Most common in metal industries and construction sites.
Factors responsible are:
 PHYSICAL – Physical capability of worker
  may not meet the job requirement.
 PHYSIOLOGICAL FACTORS:

 a) Age
 b) Sex
 c) Time
 d) Experience
Safety measures for Mechanical hazards
   All machinery must be fenced or mechanical
    interlocking or photocell.




   Machine should be fitted with emergency shut down
    system.
   Turn key system for cleaning and for repairing.




   Control system override should be monitored.
   Operator must have a safe distance from the machine.
   Strictly following SOP.
   Stop and lock button for machines.
PREVENTIVE MEASURES
 BUILDING PLANNING :
 -- Floors must be non slippery type
 -- Enough space to move easily
 -- Easy access of workers to the safety
 switches
 SAFE MATERIAL HANDLING :

 --All material handling equipments should be
 repaired and maintained properly.
    PERSONNEL PROTECTIVE DEVICES:
    -- Protection of head by using hard hats and
    helmets
    -- Ears by using ear muffs and plugs
    -- Face by using face masks
ELECTRICAL HAZARDS
   Electricity is the flow of electrons through a substance
    which allows transfer of electrical energy from one
    position to another.
How Shocks occur?
Current Level              Probable Effect on Human body
1 mA                       Slight tingling sensation.

5 mA                       Slight shock felt; not painful but disturbing.

6-30 mA                    Painful shock, muscular control is lost.

50-150 mA                  Extreme pain, respiratory arrest, severe
                            muscular contraction and death is possible
1000-4300 mA               Muscular contraction and nerve damage
                           occur. Death is most likely.
10,000 mA                  Cardiac arrest, severe burns and probable
                                    death
The most frequent causes of electrical injury/death are:
1.Contact with power lines
2.Path to ground missing or discontinuous
3.Equipment not used in manner prescribed
4.Improper use of extension and flexible cords
5. Electric shocks and burns due to poor indication
   facilities
6. wiring faults and improperly wired equipments
7. Sparking at loose connection
Safety Measures for electrical hazards
   Design a safer system
   Implement a safe electrical work program
   Observe work practice
   Use protective equipment
   Use warning labels
   Recheck the equipment everyday
   Heat producing electrical equipment
   Overhead electrical wire should have extra care
   Recheck the lines everyday
   Proper training to workers
PREVENTIVE MEASURES
 Proper maintenance of wiring and equipments.
 High voltage equipments should be properly
  enclosed.
 Indication of danger sign at every high voltage
  terminal.
 Safe work project
 Insulation, guarding , grounding,

   electrical protective devices.
 Worker should avoid working with the
  equipment in wet clothes and shoes.
 Water supply should be far away from
  electrical circuits.
CHEMICAL HAZARDS
 Chemical hazards are:

 - Toxic
 - Corrosive
 - Irritant
 - Carcinogenic
 - Flammable
 - Mutagenic
 Chemical reactions may get out of control due
 to:
 -Wrong raw materials
 -Raw materials with impurities
 -Changed operating conditions
 -Time delay
 -Equipment failure
BHOPAL GAS TRAGEDY
   Bhopal gas tragedy, considered as one of the world’s worst
    industrial chemical hazard
    It occurred on the night of Dec 2-3,1984 at union carbide
    India limited pesticide plant in Bhopal
   water entered Tank 610 containing 42 tons of MIC. The
    resulting exothermic reaction increased the temperature inside
    the tank to over 200 °C (392 °F) and raised the pressure.
    About 30 metric tons of methyl isocyanate (MIC) escaped
    from the tank into the atmosphere in 45 to 60 minutes.
   A leak of methyl isocyanate gas causes 8000 deaths, 5,58,125
    injuries.
Pictograms used in chemical hazards
Effects of chemicals on exposure
 Skin   burn
 Ache
 Anthrax
 Ulcer in hand, nose etc
 Cancer
 Irritation on wind pipe
  Many chemicals can cause severe burns, if
  they come in contact with living tissue.
 Living tissue may be destroyed by following
  chemical reactions:
     -Dehydration by strong dehydrating agents
     -Digestion by strong acids and bases
     -Oxidation by strong oxidising agents
SOME CLINICAL SYMPTOMS AND
        HAZARD CAUSING CHEMICALS

ORGAN        SYMPTOMS       CHEMICALS
EYES         Corneal and    Sulphur
             conjunctival   dioxide,
             disturbances   hydrogen
                            sulphide
NERVOUS      Drowsiness     CNS
SYSTEM                      depressants
MOUTH and    Green tongue   Vanadium
THROAT       Salivation     Mercury
Additives       Health effects
Azo dyes        Bladder Cancer

Benzene         Leukemia
Caustic Soda    Blindness & respiratory damage
Zinc salts      Skin & eye damage
Chlorine ions   Lung and Skin damage
lead            Lead poisoning
PREVENTIVE MEASURES
 Solvents used in extraction, purification of
  synthetic drugs and chemical analysis should
  be handled with care.
 Flammable and explosive chemicals should be
  kept at proper distance.
 Tolerance level for toxic chemicals set by
  federal regulation have to be followed.
 Suitable label to the chemicals for proper
  handling.
 Personal protective cloth
 Application of cream before commencement
  of work.
 Use of Goggles.
 Safety regulation and protecting measures of
  good house keeping principles.
PHARMACEUTICAL HAZARDS
Some general health hazards in manufacture of
  pharmaceuticals include:
 Dust and noise exposures
 Exposure to UV radiation
 Exposure to formaldehyde
 Repetitive motion disorders
 Formaldehyde – may cause lung cancer,
  prostate cancer. Acute exposure may cause
  pulmonary edema and pneumonia leading to
  death. Also causes allergic dermatitis

 Repetitive motion disorder– motion associated
  with packing and filling could lead to Carpal
  tunnel syndrome or Tendonitis.
 Hazards  from handling crude drugs and it’s
  extracts eg: Ipecacunha.
 Solvents eg: Benzene
 Alkaloids eg: scopolamine, emetine
 Toxic intermediate
 Final product eg: Local anaesthetic
 Miscellaneous Hazards
      Radiant energy
      Bacteria and viruses
DUST EXPLOSION
   The term dust is used if the maximum particle size of
    the solids in the mixture is 500 mm .
   Dust explosion is a rapid combustion of a dust cloud.
   Drying, milling and blending operations generate
    atmospheric and fugitive dust emissions.
   During wet granulation, compounding and tablet
    coating, hazardous air pollutants may be released to
    the atmosphere or in the workplace as process or
    fugitive emissions.
Control of dust explosion
   USE OF FILTERS
CYCLONE SEPERATORS
ELECTROSTATIC PRECIPITATORS
IMAGES FOR UNDERSTANDING
 BETTER INDUSTRIAL SAFETY
             In all places of
              employment:
             passage ways, store
              rooms and service
              rooms shall be kept
              clean and orderly in a
              sanitary condition.
   Every structure is
    required to have load
    bearing when using for
    storage.
   Floor of every work
    room shall be
    maintained clean, dry
    condition.
   Floor hole into which
    persons can accidentally
    walk shall be protected
    by a cover that leaves
    no opening more than 1
    inch wide.
   Treads on all stairs
    shall be reasonably
    slip resistant.
   This picture illustrates
    adequate slip
    resistance in place.
   Employees must be able
    to open an exit door
    from inside at all times
    without keys or special
    knowledge even in the
    dark.
   The door that
    connects any room to
    an exit route must
    swing out in direction
    of exit travel if the
    room is designed for
    more than 50 people
    or if the room is a
    high hazard area.
CONCLUSION
 Review of safety awareness and safety training
  requirements of plant employees with respect
  to hazards present in the plant.
 Review of constructor safety awareness and
  recommend suitable improvement measures.
 Systematic training of employees is necessary.
 In addition, there should be a committee in
  each department , responsible for safety in
  their departments.
REFERENCES
1. Pharmaceutical production and
   management by c.v.s subrahmanyam
   pg: 393-412
2. Hazard analysis by HACCP in safety
   management systems Q.A volume-2 pg:
   200-211
3. Perry’s chemical engineering handbook
   by Robert H.perry Don.W.Green,
   seventh edition pg:26-49
Industrial hazards and prevention systems

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Industrial hazards and prevention systems

  • 1. INDUSTRIAL HAZARDS AND PREVENTION SYSTEMS P. Raja abhilash. M.Pharm. (Ph.D.) Assistant professor S.R. college of phramacy.
  • 2. CONTENTS  INTRODUCTION  WHAT ARE INDUSTRIAL HAZARDS?  GENERAL HAZARDS IN INDUSTRIES  a) Fire accidents  b) Mechanical  c) Electrical  d) Chemical and Pharmaceutical  E) Dust explosion  IMAGES FOR UNDERSTANDING BETTER INDUSTRIAL SAFETY  CONCLUSION  REFERENCES.
  • 3. INTRODUCTION HAZARD is a situation that posses a level of threat to life, health, property or environment INDUSTRIAL HAZARD may be defined as any condition produced by industries that may cause injury or death to personnel or loss of product or property. SAFETY in simple terms means freedom from the occurrence of risk or injury or loss . INDUSTRIAL SAFETY refers to the protection of workers from the danger of industrial accidents .
  • 4. WHAT ARE INDUSTRIAL HAZARDS?  Physical --noise,vibration, heat, cold,pressure, radiation, fibres,…  Chemical – flammable/explosive materials, toxics, sensitising agents.  Biological – dust , pathogens  Psyhological – work place practices & systems, payment systems
  • 5. GENERAL HAZARDS IN INDUSTRIES  FIRE HAZARDS  MECHANICAL HAZARDS  ELECTRICAL HAZARDS  CHEMICAL HAZARDS  PHARMACEUTICAL HAZARDS  RADIATION HAZARDS  DUST EXPLOSION
  • 6. FIRE HAZARDS  Fire is an exothermic chemical reaction between oxygen and fuel.  Combustion Slow combustion eg: cotton waste burning Rapid combustion eg: petroleum product Spontaneous combustion eg: paint, scrap  The effect of fire on people take the form of skin burns .  Fire can take several different forms including jet fires ,pool fires and boiling liquid expanding vapour explosion.
  • 7. SOURCES OF FIRE HAZARDS  Hot surfaces  Combustible and flammable liquids  Heat utilization equipments (over heating)  Chemical process equipments  Lightening  Gas cylinders  Ovens and furnaces  Reactor  Welding and cutting  Spark from metal to metal contact  Carelessness
  • 9. Steps to be taken  Don’t panic  Raise the alarm  Evacuate the premises  Turn off the gas supply  Attack the fire with extinguisher  Or vacate the place In case of fire safe methods to be followed  Stair cases only to be used for evacuation  Exit doors should be closed after getting out  Go down the stair case to the ground  Walk do not run  Encounter heavy smoke crawl on the floor, do not talk, cover the nose and mouth with a wet cloth
  • 12. CONTROL OF FIRE ACCIDENTS  Fire protection is an important part of good house keeping.  Prohibition of smoking in manufacturing area  Oxygen present in atmosphere may be reduced by dilution with gases as Nitrogen, Carbon dioxide..
  • 13.  Identification and control of ignition sources in areas where flammable chemicals are stored/handled/transferred.  Elimination of ignition sources.  Careful plant layout.  Fire resistance brick walls or reinforced concrete walls.
  • 14.  Suitable exit facility to be provided.  Adequate ventilation facility.  Sprinkler with reliable water supply.  Installation of sufficient fire alarms .
  • 15. MECHANICAL HAZARDS Occurs due to:  Large number of equipments  Crowded work place conditions  Frequent interaction between worker and equipment  Insecurely fixed machines  Worn and teared parts  Failure of SOP  Dangerous Parts  Negligence  Improper maintenance of equipment Most common in metal industries and construction sites.
  • 16. Factors responsible are:  PHYSICAL – Physical capability of worker may not meet the job requirement.  PHYSIOLOGICAL FACTORS: a) Age b) Sex c) Time d) Experience
  • 17. Safety measures for Mechanical hazards  All machinery must be fenced or mechanical interlocking or photocell.  Machine should be fitted with emergency shut down system.
  • 18. Turn key system for cleaning and for repairing.  Control system override should be monitored.  Operator must have a safe distance from the machine.  Strictly following SOP.  Stop and lock button for machines.
  • 19. PREVENTIVE MEASURES  BUILDING PLANNING : -- Floors must be non slippery type -- Enough space to move easily -- Easy access of workers to the safety switches  SAFE MATERIAL HANDLING : --All material handling equipments should be repaired and maintained properly.
  • 20. PERSONNEL PROTECTIVE DEVICES: -- Protection of head by using hard hats and helmets -- Ears by using ear muffs and plugs -- Face by using face masks
  • 21. ELECTRICAL HAZARDS  Electricity is the flow of electrons through a substance which allows transfer of electrical energy from one position to another. How Shocks occur? Current Level Probable Effect on Human body 1 mA Slight tingling sensation. 5 mA Slight shock felt; not painful but disturbing. 6-30 mA Painful shock, muscular control is lost. 50-150 mA Extreme pain, respiratory arrest, severe muscular contraction and death is possible 1000-4300 mA Muscular contraction and nerve damage occur. Death is most likely. 10,000 mA Cardiac arrest, severe burns and probable death
  • 22. The most frequent causes of electrical injury/death are: 1.Contact with power lines 2.Path to ground missing or discontinuous 3.Equipment not used in manner prescribed 4.Improper use of extension and flexible cords 5. Electric shocks and burns due to poor indication facilities 6. wiring faults and improperly wired equipments 7. Sparking at loose connection
  • 23. Safety Measures for electrical hazards  Design a safer system  Implement a safe electrical work program  Observe work practice  Use protective equipment  Use warning labels  Recheck the equipment everyday  Heat producing electrical equipment  Overhead electrical wire should have extra care  Recheck the lines everyday  Proper training to workers
  • 24. PREVENTIVE MEASURES  Proper maintenance of wiring and equipments.  High voltage equipments should be properly enclosed.  Indication of danger sign at every high voltage terminal.  Safe work project  Insulation, guarding , grounding, electrical protective devices.
  • 25.  Worker should avoid working with the equipment in wet clothes and shoes.  Water supply should be far away from electrical circuits.
  • 26. CHEMICAL HAZARDS  Chemical hazards are: - Toxic - Corrosive - Irritant - Carcinogenic - Flammable - Mutagenic
  • 27.  Chemical reactions may get out of control due to: -Wrong raw materials -Raw materials with impurities -Changed operating conditions -Time delay -Equipment failure
  • 28. BHOPAL GAS TRAGEDY  Bhopal gas tragedy, considered as one of the world’s worst industrial chemical hazard  It occurred on the night of Dec 2-3,1984 at union carbide India limited pesticide plant in Bhopal  water entered Tank 610 containing 42 tons of MIC. The resulting exothermic reaction increased the temperature inside the tank to over 200 °C (392 °F) and raised the pressure. About 30 metric tons of methyl isocyanate (MIC) escaped from the tank into the atmosphere in 45 to 60 minutes.  A leak of methyl isocyanate gas causes 8000 deaths, 5,58,125 injuries.
  • 29.
  • 30. Pictograms used in chemical hazards
  • 31. Effects of chemicals on exposure  Skin burn  Ache  Anthrax  Ulcer in hand, nose etc  Cancer  Irritation on wind pipe
  • 32.  Many chemicals can cause severe burns, if they come in contact with living tissue.  Living tissue may be destroyed by following chemical reactions: -Dehydration by strong dehydrating agents -Digestion by strong acids and bases -Oxidation by strong oxidising agents
  • 33. SOME CLINICAL SYMPTOMS AND HAZARD CAUSING CHEMICALS ORGAN SYMPTOMS CHEMICALS EYES Corneal and Sulphur conjunctival dioxide, disturbances hydrogen sulphide NERVOUS Drowsiness CNS SYSTEM depressants MOUTH and Green tongue Vanadium THROAT Salivation Mercury
  • 34. Additives Health effects Azo dyes Bladder Cancer Benzene Leukemia Caustic Soda Blindness & respiratory damage Zinc salts Skin & eye damage Chlorine ions Lung and Skin damage lead Lead poisoning
  • 35. PREVENTIVE MEASURES  Solvents used in extraction, purification of synthetic drugs and chemical analysis should be handled with care.  Flammable and explosive chemicals should be kept at proper distance.  Tolerance level for toxic chemicals set by federal regulation have to be followed.  Suitable label to the chemicals for proper handling.
  • 36.  Personal protective cloth  Application of cream before commencement of work.  Use of Goggles.  Safety regulation and protecting measures of good house keeping principles.
  • 37. PHARMACEUTICAL HAZARDS Some general health hazards in manufacture of pharmaceuticals include:  Dust and noise exposures  Exposure to UV radiation  Exposure to formaldehyde  Repetitive motion disorders
  • 38.  Formaldehyde – may cause lung cancer, prostate cancer. Acute exposure may cause pulmonary edema and pneumonia leading to death. Also causes allergic dermatitis  Repetitive motion disorder– motion associated with packing and filling could lead to Carpal tunnel syndrome or Tendonitis.
  • 39.  Hazards from handling crude drugs and it’s extracts eg: Ipecacunha.  Solvents eg: Benzene  Alkaloids eg: scopolamine, emetine  Toxic intermediate  Final product eg: Local anaesthetic  Miscellaneous Hazards  Radiant energy  Bacteria and viruses
  • 40. DUST EXPLOSION  The term dust is used if the maximum particle size of the solids in the mixture is 500 mm .  Dust explosion is a rapid combustion of a dust cloud.  Drying, milling and blending operations generate atmospheric and fugitive dust emissions.  During wet granulation, compounding and tablet coating, hazardous air pollutants may be released to the atmosphere or in the workplace as process or fugitive emissions.
  • 41. Control of dust explosion  USE OF FILTERS
  • 44. IMAGES FOR UNDERSTANDING BETTER INDUSTRIAL SAFETY In all places of employment: passage ways, store rooms and service rooms shall be kept clean and orderly in a sanitary condition.
  • 45. Every structure is required to have load bearing when using for storage.
  • 46. Floor of every work room shall be maintained clean, dry condition.
  • 47. Floor hole into which persons can accidentally walk shall be protected by a cover that leaves no opening more than 1 inch wide.
  • 48. Treads on all stairs shall be reasonably slip resistant.  This picture illustrates adequate slip resistance in place.
  • 49. Employees must be able to open an exit door from inside at all times without keys or special knowledge even in the dark.
  • 50. The door that connects any room to an exit route must swing out in direction of exit travel if the room is designed for more than 50 people or if the room is a high hazard area.
  • 51. CONCLUSION  Review of safety awareness and safety training requirements of plant employees with respect to hazards present in the plant.  Review of constructor safety awareness and recommend suitable improvement measures.  Systematic training of employees is necessary.  In addition, there should be a committee in each department , responsible for safety in their departments.
  • 52. REFERENCES 1. Pharmaceutical production and management by c.v.s subrahmanyam pg: 393-412 2. Hazard analysis by HACCP in safety management systems Q.A volume-2 pg: 200-211 3. Perry’s chemical engineering handbook by Robert H.perry Don.W.Green, seventh edition pg:26-49