Inbreeding coefficient Inbreeding and self-fertilization Genotypes mate at random with respect to their genotype at this particular locus. There are many ways in which this assumption might be violated: • Some genotypes may be more successful in mating than others, sexual selection. • Genotypesthataredifferentfromoneanothermaymatemoreoftenthanexpecteddisassortative mating, e.g., self-incompatibility alleles in flowering plants, MHC lociinhumans (the smelly t-shirt experiment) • Genotypesthataresimilartooneanothermaymatemoreoftenthanexpectedassortativemating. • Some fraction of the offspring produced may be produced asexually. • Individuals may mate with relatives inbreeding. – self-fertilization – sib-mating – first-cousin mating – parent-offspring mating – etc.