Erythroderma is defined as the scaling erythematous dermatitis involving 90% or more of the cutaneous surface.
Also known as exfoliative dermatitis
Idiopathic exfoliative dermatitis – also known as the “red man syndrome”, is characterized by marked palmoplantar keratoderma, dermatopathic lymphadenopathy,increased IgE.
Increased skin perfusion leads to
Temperature dysregulation >
Resulting in skin loss and hypothermia >
High output state >
Cardiac failure
BMR raises to compensate for heat loss
Increased dehydration due to transpiration (similar to burns)
All lead to negative nitrogen balance and characterized by edema, hypoalbuminemia, loss of muscle mass.
Erythroderma is defined as the scaling erythematous dermatitis involving 90% or more of the cutaneous surface.
Also known as exfoliative dermatitis
Idiopathic exfoliative dermatitis – also known as the “red man syndrome”, is characterized by marked palmoplantar keratoderma, dermatopathic lymphadenopathy,increased IgE.
Increased skin perfusion leads to
Temperature dysregulation >
Resulting in skin loss and hypothermia >
High output state >
Cardiac failure
BMR raises to compensate for heat loss
Increased dehydration due to transpiration (similar to burns)
All lead to negative nitrogen balance and characterized by edema, hypoalbuminemia, loss of muscle mass.
ABSTRACT- The treatment of carbuncle is early administration of antibiotics and surgery. The commonest surgical approach is Saucerization and Incision & Drainage (I&D). Two cases are presented here, one underwent Saucerization and then primary split thickness skin grafting. Another un-derwent I&D for her carbuncle. They were followed up for 8 weeks to assess their outcome. Saucerization produced the shortest length of hospital stay while I&D resulted in shortest wound healing. As a new modality of treatment now-a-days two new modalities gaining popularity for better cosmetic purpose: primary split thickness skin grafting & transposition of local skin/musculocutaneous flap.
Keywords: carbuncle, surgery, good glycemic control
A case presentation requiring wide debridement and a trephine defunctioning colostomy with operative finding photos. Includes how to diagnose and manage this potentially fatal condition.
By focusing on the individual’s unique needs and preferences, Personalized Skinvestimalism aims to create a highly tailored and effective skincare experience, promoting optimal skin health and satisfaction.
Simplify, Optimize, Elevate Your Skincare SpiritualityMohammad Baghaei
While Skinvestimalism is primarily focused on simplifying and optimizing skincare routines, it can have spiritual undertones for individuals who choose to infuse a mindful and intentional approach into their skincare practices.
While Skinvestimalism itself is not inherently spiritual, individuals have the flexibility to infuse spiritual elements into their skincare practices by approaching it with mindfulness, intention, and a connection to broader spiritual principles. The spiritual aspect largely depends on the individual’s personal beliefs and how they choose to engage with their skincare routines.
Tailoring Beauty | Your Personalized Path with SkinvestimalismMohammad Baghaei
Tailoring Beauty | Your Personalized Path with Skinvestimalism
Skinvestimalism can be personalized for everyone by embracing the following principles:
• Tailored Base Products: Offer a range of base skincare products that cater to different skin types (oily, dry, combination) and concerns (aging, acne-prone, sensitive). This allows individuals to start with a product that suits their fundamental needs.
• Customization Options: Provide customization options, such as additional boosters or add-ons, allowing users to tailor their skincare routine based on specific concerns. These could include serums for targeted issues like hyperpigmentation or fine lines.
www.skinvestimalism.com
Dr.Mohammad Baghaei , Cosmetic Scientist , PharmaD
AI Empowering Skinvestimalism | Beauty with Transparency and TechnologyMohammad Baghaei
Artificial Intelligence (AI) can play a significant role in advancing the principles of Skinvestimalism in skincare. Here are some ways AI can be beneficial:
• Personalized Formulations: AI can analyze individual skin types, conditions, and preferences to create personalized skincare formulations tailored to specific needs.
• Ingredient Analysis: AI can efficiently analyze vast amounts of data on skincare ingredients, helping to identify the most effective and beneficial components for various skin concerns.
• Product Recommendations: AI algorithms can provide personalized product recommendations based on an individual’s skin type, concerns, and environmental factors, promoting a more targeted and streamlined skincare routine.
• Skin Health Monitoring: AI-powered tools can monitor changes in skin health over time, adapting skincare routines dynamically to address evolving needs.
• Product Development: AI can assist in formulating new products by predicting ingredient interactions, optimizing formulations for effectiveness, and even suggesting sustainable alternatives.
By leveraging AI in these ways, Skinvestimalism can integrate cutting-edge technology to enhance personalization, efficiency, and sustainability in the skincare industry.
Dr.Mohammad Baghaei , Cosmetic Scientist , PharmaD
www.skinvestimalism.com
Transparency | A Fundamental Principle of the Skinvestimalism Approach to Cos...Mohammad Baghaei
Skinvestimalism can enhance transparency in skincare products through several key practices:
• Clear Ingredient Communication: Emphasizing straightforward communication of ingredients on product labels, avoiding complex terminology, and providing information about the purpose of each ingredient enhances transparency.
• Detailed Product Information: Offering detailed information on product packaging, websites, or through QR codes can provide consumers with insights into the formulation, usage, and benefits of the product.
• Minimalist Formulations: By adhering to minimalist principles, Skinvestimalism minimizes the number of ingredients in formulations. This simplicity promotes transparency, as consumers can easily understand what they are applying to their skin.
• Sustainable Sourcing: Clearly communicating sustainable sourcing practices for ingredients demonstrates a commitment to transparency and environmental responsibility. This information may include details on ethical sourcing, cruelty-free practices, and eco-friendly packaging.
• Educational Content: Providing educational content about skincare and product usage helps consumers make informed decisions. This could involve including pamphlets, online resources, or video content explaining the product and its benefits.
• Independent Certifications: Seeking certifications from reputable third-party organizations can validate claims about natural or organic ingredients, cruelty-free practices, and overall product quality. Displaying these certifications on packaging adds credibility and transparency.
• Consumer Feedback: Encouraging and showcasing honest reviews and feedback from consumers fosters transparency. This provides real-life insights into how the product has worked for others.
Revolutionizing Pro-Aging Self-Care | The Unparalleled Precision of SVM-AiMohammad Baghaei
In an era where self-care meets cutting-edge technology, the amalgamation of Skinvestimalism with Artificial Intelligence (SVM-Ai) emerges as a pioneering solution in pro-aging skincare. This detailed article explores SVM-Ai’s role in reshaping the landscape of self-care, providing unparalleled precision and personalization for individuals who embrace and celebrate the natural process of aging.
1. Introduction: Navigating the Beauty of Aging
The introduction paints a vivid picture of the evolving perceptions of beauty and self-care. It introduces SVM-Ai as a transformative force, poised to redefine the pro-aging landscape by seamlessly integrating advanced technology with a mindset that celebrates the beauty inherent in the aging process.
2. SVM-Ai Unveiled: A Symphony of Precision and Personalization
This section delves into the intricacies of SVM-Ai, highlighting its core components and how AI-driven algorithms orchestrate a symphony of precision and personalization. From analyzing individual skin conditions to crafting tailor-made recommendations, SVM-Ai sets a new standard for precision in pro-aging self-care.
3. Personalized Pro-Aging Skincare: Nurturing Individual Beauty
The article navigates through SVM-Ai’s ability to offer personalized skincare recommendations, emphasizing its role in recognizing and embracing the unique needs of aging skin. This personalized approach becomes a cornerstone in nurturing individual beauty and fostering a self-care routine that aligns seamlessly with pro-aging principles.
4. Minimalism and Purpose: The Skinvestimalism Connection
An exploration of SVM-Ai’s connection with Skinvestimalism’s minimalist philosophy follows. The article details how SVM-Ai ensures that recommended products and routines are purposeful, effective, and in perfect harmony with the principles of healthy aging, fostering intentional and minimalistic self-care practices.
5. Prevention and Intervention: Dynamic Pro-Aging Skincare
The integration of AI equips SVM-Ai to assess early signs of aging and prescribe proactive interventions. This section elaborates on the dynamic nature of SVM-Ai’s approach, focusing on maintaining skin health before visible signs of aging manifest. Prevention becomes a key aspect of the self-care journey.
6. Continuous Adaptation: Tailoring Solutions Over Time
SVM-Ai’s dynamic adaptability takes center stage, illustrating how the system continuously evolves recommendations based on real-time data. The article discusses how this adaptability ensures that the pro-aging self-care routine remains not only responsive but also tailored to the changing needs of aging skin throughout the individual’s unique journey.
7. Education and Empowerment: Informed Self-Care Choices
Both SVM-Ai and pro-aging share a commitment to educating users. The article details how SVM-Ai acts as a source of valuable information, empowering individuals to make informed choices that contribute to their long-term skin health. Education becomes
Revolutionizing Skincare Marketing | The Integration of Neuromarketing under ...Mohammad Baghaei
In the ever-evolving landscape of skincare, the marriage of advanced technology and consumer psychology is reshaping the way we approach marketing. Under the SVM-Ai (Skinvestimalism with Artificial Intelligence) umbrella, the integration of neuromarketing principles emerges as a transformative force, promising a more personalized, minimalist, sustainable, and effective skincare experience.
Personalized Skincare Recommendations
At the core of SVM-Ai lies the concept of personalized skincare. AI algorithms analyze vast datasets, incorporating neuromarketing insights to decipher individual emotional responses and preferences. This synergy enables the creation of skincare recommendations that go beyond skin type, delving into the realm of personal emotions and connections with beauty products.
Minimalist and Purposeful Design
Under the SVM-Ai and neuromarketing collaboration, visual elements take center stage. Minimalist design, a hallmark of Skinvestimalism, is optimized based on neuromarketing insights. Understanding the subconscious impact of visual stimuli allows for purposeful design choices that resonate with consumers on a deeper, emotional level.
Sustainable Packaging and Ethical Practices
The sustainability pillar of Skinvestimalism is elevated with neuromarketing’s influence. AI algorithms decode consumer preferences revealed through neuromarketing, ensuring that sustainable packaging designs align seamlessly with subconscious desires. The result is not just eco-friendly packaging but an emotionally resonant commitment to ethical practices.
Clean Beauty Messaging
The clean beauty movement gains a new dimension through the fusion of SVM-Ai and neuromarketing. Crafting narratives that tap into consumers’ subconscious associations with health and well-being, the collaboration ensures that clean beauty messaging is not just transparent but emotionally compelling.
Futuristic Innovation
As the skincare industry embraces futuristic innovation, SVM-Ai integrates neuromarketing to captivate consumers on a subconscious level. Cutting-edge experiences are tailored to evoke positive emotional responses, creating a futuristic narrative that aligns with the desires of the modern consumer.
Effective Product Positioning
The effectiveness of product positioning is elevated with the integration of neuromarketing data. Understanding consumers’ emotional responses to specific skincare formulations and benefits allows for strategic positioning that resonates on a personal and emotional level.
Inclusive and Diverse Representation
The inclusivity pillar of Skinvestimalism is enriched by AI’s capacity to ensure diverse representation in marketing materials. Combining neuromarketing insights, the collaboration seeks not only to represent diversity but to connect with a broader audience on a subconscious level.
Technology-Enhanced User Experience
In the realm of technology-driven user experiences, SVM-Ai and neuromarketing work in harmony. AI algorithms tailor user
SvmAi | Precision in Personalized Skincare for Your Unique RequirementsMohammad Baghaei
SvmAi embodies the pinnacle of skincare innovation, seamlessly merging cutting-edge technologies and expert skincare principles to craft a personalized and evolving skincare experience.
Data-Driven Understanding:
At the core of SvmAi’s prowess is a meticulous data-driven approach, where advanced sensors and data collection mechanisms initiate an in-depth exploration of your skin’s internal and external dynamics. This sets the stage for a sophisticated understanding of your skin’s unique characteristics, sensitivities, and inherent traits.
In-Depth Analysis:
SvmAi goes beyond surface-level assessments, delving into the intricacies of your skin type. Every nuance is considered, ensuring a comprehensive analysis that acknowledges your skin’s interconnection with the surrounding environment.
Environmental Considerations:
Recognizing that your skin exists in a dynamic ecosystem, SvmAi factors in environmental influences such as UV exposure, pollution levels, and climate variations. This holistic approach transcends reactive measures, allowing your skincare regimen to anticipate and adapt to the changing conditions your skin faces.
Tailored Skincare Regimen:
The culmination of this precision analysis is a bespoke skincare plan. Rejecting the one-size-fits-all approach, SvmAi crafts a regimen tailored to your skin’s specific requirements. From product selection to application intricacies, every detail is meticulously curated to optimize your skin’s health and vitality.
Data Processing Excellence:
SvmAi’s exceptional understanding is underpinned by robust data processing capabilities. The power of artificial intelligence efficiently navigates vast datasets, ensuring not only accuracy in comprehending your skin but also laying the groundwork for a responsive and adaptive skincare strategy.
Pattern Recognition Mastery:
SvmAi’s artificial intelligence elevates skincare to an art form through pattern recognition. Beyond static characteristics, it adeptly identifies dynamic changes over time, capturing trends related to seasonal variations, lifestyle shifts, and other evolving factors. This mastery ensures that SvmAi’s skincare recommendations evolve harmoniously with your skin’s unique journey.
Adapting to Dynamic Changes:
Just as your skin undergoes dynamic changes, SvmAi’s adaptive design recalibrates seamlessly. Whether responding to internal shifts like hormonal fluctuations or external influences like climate changes, SvmAi remains agile, providing a precise and evolving skincare strategy.
In essence, SvmAi is not merely a skincare tool; it’s a harmonious fusion of advanced technologies and skincare expertise. It doesn’t just understand your skin; it evolves with it. Through data processing, pattern recognition, and a commitment to adapting to dynamic changes, SvmAi ensures that your skincare experience is not just personalized but a continuous and transformative journey towards optimal wellbeing
Dr.Mohammad Baghaei , Cosmetic Scientist , PharmaD
www.s
When discussing Skinvestimalism, encompasses the contemporary concerns of humanity related to environmental and sustainability issues. This includes considerations such as energy consumption, air pollution, prioritizing clean energy, advocating for the use of organic and clean beauty products, minimizing the consumption of agricultural pesticides and herbicides, and reducing carbon dioxide production.
As the European Union commits to climate neutrality by 2050, the beauty industry stands at a transformative crossroads. SvmAi, a revolutionary integration of artificial intelligence and a minimalistic ethos, emerges as the guiding force steering the cosmetics sector towards a sustainable revolution.
Companies are prioritizing sustainability, driven by heightened consumer awareness. A 2020 Institute for Business Value report reveals that 60% of consumers are ready to alter buying habits to reduce environmental impact, with 80% emphasizing the importance of sustainability. A substantial portion is willing to pay more for products from sustainable brands. In this transformative landscape, SvmAi stands as a trailblazer, blending artificial intelligence and a minimalistic ethos to address consumer demands for eco-friendly cosmetics. SvmAi's personalized recommendations and sustainability commitment position it as a pioneer, shaping a more responsible and environmentally conscious beauty industry.
Dr.Mohammad Baghaei , Cosmetic Scientist , PharmaD
www.skinvestimalism.com
Mastering the Art of Wrinkle Rejuvenation:
A Comprehensive Guide to Types (16 Types), Causes, Prevention, Choosing the Right Treatment, and Cutting-Edge Treatments
By : Dr. Mohammad Baghaei , Cosmetic Scientist , PharmD .
Introduction: As the clock ticks forward, wrinkles emerge as tangible reminders of the inexorable passage of time. This comprehensive guide embarks on an illuminating journey into the intricate world of wrinkles, unraveling the diverse types, underlying causes, prevention strategies, the essential element of choosing the right treatment, and cutting-edge treatments.
Types of Wrinkles (16 TYPES): Wrinkles, intricate storytellers etched on our skin, unveil a diverse spectrum of nuances, each revealing a unique facet of the aging journey:
1. Dynamic Wrinkles:
• Characteristics: Responsive to facial movements, e.g., crow’s feet and forehead lines.
• Examples: Crow’s feet, forehead lines, and smile lines showcase the dynamic nature of facial expressions.
2. Static Wrinkles:
• Characteristics: Present even at rest, static wrinkles reflect a loss of skin elasticity and the relentless pull of gravity over time.
• Examples: Marionette lines, nasolabial folds, and necklines signify the enduring imprints of aging.
3. Wrinkle Folds:
• Characteristics: Deep grooves formed by sagging facial structures, these folds narrate the natural ebb and flow of the skin's architecture.
• Examples: Nasolabial folds exemplify the impact of facial structure on the skin's appearance.
4. Compression Wrinkles:
• Characteristics: Arising from prolonged facial compression against surfaces, such as pillows during sleep, these wrinkles depict imprints of life's moments.
5. Permanent Elastic Creases:
• Characteristics: Resulting from factors like sun exposure, pollution, and smoking, these creases persistently form around the upper lip, cheeks, neck, and décolletage.
6. Expression Lines:
• Characteristics: Subtle and revealing, these lines, commonly found around the eyes, forehead, and mouth, bear witness to a life rich in varied facial expressions.
7. Elastic Wrinkles:
• Characteristics: Manifesting as fine lines during facial movements and at rest, elastic wrinkles mirror the evolving nature of the skin's resilience over time.
8. Gravitational Folds:
• Characteristics: As gravity influences facial tissues, nasolabial folds and jowls emerge, shaping the contours of aging faces.
9. Dry Skin-Induced Wrinkles:
• Characteristics: Dry skin intensifies the journey of aging, robbing the skin of moisture and natural oils, making it susceptible to fine lines.
10. Compression Lines:
• Characteristics: Temporary imprints of life's moments, these lines reveal tales of sleep positions and daily routines, etched on the skin like imprints on a well-read book.
11. Crinkle Lines:
• Characteristics: Delicate and superficial, crinkle lines decorate the skin's surface, reflecting a life well-lived around the eyes and mouth.
12. Atrophic Wrinkles:
• Characteristics: Reflecting d
In the journey of skincarefinding balance is the art.pdfMohammad Baghaei
"In the journey of skincare, finding balance is the art of avoiding extremes—neither drying the skin excessively nor drowning it in moisture. It's about embracing a routine that nurtures harmony, regulating oil, and fostering a natural radiance, creating a foundation for enduring skin health."
Dr. Mohammad Baghaei Cosmetic Scientist , PharmD.
زنبور عسل( Apis mellifera) یا honeybee گونهای زنبور است که عسل میسازد. زنبور عسل این کار را با گردآوری شهد گلها در کندو انجام میدهد.
ميدانيم زنبورهای هر کندو یکی از سه نوع زنبور ملکه، زنبور نر و زنبور کارگر هستند.
ملکه، مادر اغلب زنبورهای موجود در کندو است.
جنسیت ملکه ماده بوده و مهمترین وظیفهاش تخمگذاری میباشد.
💥اپي ژنتيك چيست ؟؟
واژه" اپي ژنتيك "از كلمه يوناني "اپيژنزيس" گرفته شده است و اشاره به تغييرات ژنتيكي در هنگام بيان ژن دارد.
اين تغييرات كه حاصل تغيير در فنوتيپ اما بدون تغيير در در ژنوتيپ است مي تواند به طور معمول و طبيعي رخ دهد. اين تغيير هم چنين مي تواند تحت تاثير فاكتورهاي متعددي مانند ؛ سن ، محيط ، روش زندگي و بيماري رخ دهد
دکتر محمد بقایی
رنگ ها از یک سو نقشی کلیدی در ایجاد جذابیت و موفقیت در مارکت دارند و از سویی دیگر به واسطه خطرات احتمالی ناشی از نفوذ آنها به داخل بافتها و گردش خون همواره در کانون نگرانی های متخصصین و دانشمندان کازمتیک بخصوص آنهایی که در حوزه رگولاتوری و حفظ سلامت جامعه مشغول بکارند قرار دارند .
رنگ در کازمتیک
رنگ نقشی کلیدی در ایجاد جاذبه برای مصرف کننده نهایی در انتخاب محصول و در نهایت موفقیت در مارکت دارد . مواد رنگی معمولا به دو منظور به محصولات کازمتیک اضافه می گردند :
1- تغییر رنگ و ظاهر محصول در راستای اصلاح رنگ مواد موجود در آن یا رنگ مخلوط حاصل ، ایجاد جاذبه و دلپذیر تر نمودن آن
2- برجای گذاشتن رنگ بر پوست ، مو و ناخن در جهت اصلاح ظاهر این ارگانهای بدن یا ایجاد رنگی جدید و جذاب به منظر اهدافی ثانویه ( مراسم خاص ، ایفای نقشی ویژه ...)
دکتر محمد بقایی
دکتر محمد بقایی نگاهی گذرا بر آروماتراپی یا رایحه درمانیMohammad Baghaei
آروماتراپي Aromatherapy يا رايحه درماني نام خود را از دو كلمه آروما Aroma به معني رايحه و بو و تراپي Therapy يا درمان گرفته است .
اين نوع درمان روشي طبيعي براي التيام روح ، بدن و افكار يك شخص است.
آروماتراپي در بسياري از تمدن هاي قديم همانند چين ، مصر ، هندوستان و ايران به عنوان يك طب مكمل و يا جايگزين مورد استفاده قرار مي گرفته است و قدمتي شايد حداقل ٦٠٠٠ ساله دارد.
امروزه آروماتراپي به عنوان يك روش درماني براي عوارض و حالات بيمارگونه مختلفي كاربرد دارد.
نگاهی گذرا بر چند عامل روشن كننده پوست با مكانيسم عمل مهار آنزيم تيروزينازMohammad Baghaei
رنگدانه هاي ملانين مسئول رنگ دهي به پوست ، مو و چشمان ماست و نقش مهمي در محافظت از آنها در برابر انرژي هاي خطرناك خورشيدي ايفا ميكند.
در برخي از موارد از جمله در زمان بروز لك و تيرگي پوست كنترل ساخت و توزيع ملانين در سطح پوست بدن به يكي از اهداف درماني متخصصين درماتولوژي و كازمتولوژي مبدل ميشود .
بسياري از عوامل روشن كننده كه در فرمولاسيون محصولات درموكازمتيك كاربرد دارند با سركوب ملانوژنزيز از طريق مهار فعاليت آنزيم تيروزيناز يا تسهيل تخريب تيروزيناز عمل مي نمايند.
به پروسه پيچيده ايي كه سبب شكل گيري ملانين در ملانوسيتها مي گردد ملانوژنزيز گفته ميشود.
"Radiant Resilience: A Comprehensive TLC Guide to Urban Skincare Bliss"Mohammad Baghaei
"Radiant Resilience: A Comprehensive TLC Guide to Urban Skincare Bliss"
By: Dr Mohammad Baghaei , Cosmetic Scientist, PharmD.
In the hustle and stress of city life, where our skin often bears the brunt of environmental challenges, adopting a meticulous TLC (Tender Loving Care) skincare regimen becomes paramount. This holistic approach extends beyond mere routines and products; it's a journey of self-acceptance, acknowledging and embracing our unique skin conditions.
Debunking Myths for a Radiant Base:
Begin by discarding the myth that moisturizing is dispensable for oily skin. Regardless of your skin type, moisturizing with the right ingredients proves indispensable. Facial acids seamlessly weave into your routine, countering the toll of city life on your skin.
TLC as a Lifestyle Commitment:
TLC transcends a skincare routine; it's a commitment to a harmonious relationship with your skin. Embrace tranquility, radiate stressless serenity, and create a personalized sanctuary amid the urban cacophony. Effective skincare becomes a ritual, an act of self-love that revitalizes your skin and elevates your well-being.
Pillars of Radiant Resilience:
Consistency is key, so establish a routine and be patient for lasting results. Understand your skin type, choose products accordingly, and prioritize sunscreen for daily protection. Gentle cleansing, the gradual introduction of actives, hydration, a balanced diet, adequate sleep, and listening to your skin are additional pillars of this comprehensive guide.
Celebrating Diversity and Cultivating Confidence:
Central to the TLC philosophy is acknowledging and embracing your skin conditions. Acceptance becomes the foundation for a positive and nurturing skincare journey, celebrating the diversity of your skin and cultivating confidence that shines through from within.
Traversing the Urban Landscape with TLC:
Traverse the bustling cityscape with TLC as your compass, unlocking the radiant and resilient beauty that lies within – a testament to the tender loving care your skin and soul deserve. In the face of modern challenges, let TLC be your urban skincare bliss, a celebration of self-love in every revitalizing drop and soothing moment.
2023-24 dermocosmetic trends forecast , By Dr . Mohammad BaghaeiMohammad Baghaei
Conceptions of Skincare and dermocosmetic products are constantly changing, resulting in a constant slew of new and innovative developments in the cosmetic industry.
The dermocosmetics industry has always been at the forefront of innovation and reinvention, and the next year will be no exception.With all that’s going on, we shall be ready to deep dive into the ever-changing world so I decided to introduce you my forecast provide trends that will continue to push the skincare industry forward in 2023
The Role of Oxygen in Skin Health and Strategies for Enhanced Oxygenation.pptxMohammad Baghaei
The Role of Oxygen in Skin Health and Strategies for Enhanced Oxygenation
Oxygen, a vital component in skin health, influences diverse processes crucial for maintaining the skin's overall well-being. Understanding the pivotal role of oxygen in the skin sets the foundation for implementing effective strategies to enhance skin oxygenation. Here, we delve into key aspects of oxygen's role and detail practices that can optimize skin oxygenation.
Understanding and Managing Scalp Acne, A Comprehensive Guide pptxMohammad Baghaei
Scalp acne, scientifically termed scalp folliculitis, is a common yet often perplexing condition resulting from inflamed hair follicles triggered by excess oil, bacterial presence, or the accumulation of dead skin cells. In this thorough guide, Dr. Mohammad Baghaei delves into the intricate details of the causes and offers nuanced strategies for effective management.
Scalp acne manifests as the inflammation of hair follicles, leading to the development of small, itchy bumps or pimples on the scalp. A nuanced comprehension of the contributing factors is vital for crafting targeted management approaches.
Beauty Quotes 1, Science is Beauty, Beauty is Science…Mohammad Baghaei
Science is Beauty, Beauty is Science…
Alright let's start with a question. Could it be that all things beautiful, all art, all design, could actually be explored from a scientific angle, and could actually be defined by science?
If we begin to see science as beauty, then we can begin to see why qualities such as love and collaboration can sit beside those of mechanical order and systematic law. Indeed, science is beauty. Science is simply the study of innate beauty within all form and all live. A true scientist will naturally fall in love with all that he/she studies, for the true scientist is traversing the realms of God's work of art. And if science is beauty, then beauty must indeed be science.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
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An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
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The Indian economy is classified into different sectors to simplify the analysis and understanding of economic activities. For Class 10, it's essential to grasp the sectors of the Indian economy, understand their characteristics, and recognize their importance. This guide will provide detailed notes on the Sectors of the Indian Economy Class 10, using specific long-tail keywords to enhance comprehension.
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2. HIDRADENITIS SUPPURATIVA
Disease of the follicle
Deep tender nodules in the groin, axilla,
buttocks
Difficult to treat
May respond to Accutane
2
3. What is hidradenitis suppurativa?
Hidradenitis suppurativa is a chronic, recurrent,
and painful disease in which there is inflammation
in areas of the apocrine sweat glands. These
glands are found mainly in the armpits and groins.
Within hidradenitis there is a blockage of the hair
follicles. This causes a mixture of boil-like lumps,
areas leaking pus, and scarring.
Hidradenitis tends to begin in early life, and is
more common in women, black and
Mediterranean people. It affects about 1% of the
population. Hidradenitis often starts at puberty,
and is most active between the ages of 20 and 40
years, and in women, can resolve at menopause.
It is 3 times more common in females than in
males.
hidradenitis suppurativa
3
4. What are the clinical features of
hidradenitis suppurativa?
Risk factors include:
1. Other family members with hidradenitis suppurativa
2. Obesity and insulin resistance/metabolic syndrome
3. Cigarette smoking
4. Follicular occlusion disorders: acne conglobata, dissecting cellulitis,
pilonidal sinus
5. Inflammatory bowel disease (Crohn disease)
6. Rare autoinflammatory syndromes associated with abnormalities of
PSTPIP1 gene*
* PAPA syndrome (Pyogenic Arthritis, Pyoderma gangrenosum and Acne), PASH syndrome (Pyoderma
gangrenosum, Acne, Suppurative Hidradenitis) and PAPASH syndrome (Pyogenic Arthritis, Pyoderma
gangrenosum, Acne, Suppurative Hidradenitis)
4
5. What causes hidradenitis suppurativa?
Hidradenitis suppurativa is an
autoinflammatory disorder. Although the exact
cause is not yet understood, contributing
factors include:
o Friction from clothing and body folds
o Aberrant immune response to commensal
bacteria
o Follicular occlusion
o Release of pro-inflammatory cytokines
o Inflammation causing rupture of the
follicular wall and destroying apocrine
glands and ducts
o Secondary bacterial infection
o Certain drugs
5
6. Signs
Hidradenitis can affect a single or multiple
areas in the armpits, neck, submammary
area, and inner thighs. Anogenital
involvement most commonly affects the
groin, mons pubis, vulva (in females),
sides of the scrotum (in males), perineum,
buttocks and perianal folds
6
7. Signs
Signs include:
Open and closed comedones
Painful firm papules and larger nodules
Pustules, fluctuant pseudocysts and
abscesses
Pyogenic granulomas
Draining sinuses linking inflammatory
lesions
Hypertrophic and atrophic scars
7
8. Severity
The severity and extent of hidradenitis suppurativa is
recorded at assessment and when determining the impact
of a treatment. The Hurley system describes three distinct
clinical stages:
1. Solitary or multiple, isolated abscess formation without
scarring or sinus tracts
2. Recurrent abscesses, single or multiple widely
separated lesions, with sinus tract formation
3. Diffuse or broad involvement, with multiple
interconnected sinus tracts and abscesses.
8
9. Severity
Severe hidradenitis (Hurley Stage 3) has been
associated with:
Male gender
Axillary and perianal involvement
Obesity
Smoking
Disease duration
9
10. What is the treatment for hidradenitis
suppurativa?
General measures:
Weight loss; follow low-glycaemic, low-dairy diet
Smoking cessation: this can lead to improvement within a few months
Loose fitting clothing
Daily unfragranced antiperspirants
If prone to secondary infection, wash with antiseptics or take bleach baths
Apply hydrogen peroxide solution or medical grade honey to reduce
malodour
Apply simple dressings to draining sinuses
Analgesics, such as paracetamol (acetaminophen), for pain control.
10
11. Medical management of hidradenitis
suppurativa
Medical management of hidradenitis
suppurativa is difficult. Treatment is
required long term. Effective options are
listed below.
11
12. Antibiotics
• Topical clindamycin, with benzoyl peroxide to
reduce bacterial resistance
• Short course of oral antibiotics for acute
staphylococcal abscesses, eg flucloxacillin
• Prolonged courses (minimum 3 months) of
tetracycline, metronidazole, cotrimoxazole,
fluoroquinolones or dapsone for their anti-
inflammatory action
• Six-to-twelve week courses of the
combination of clindamycin (or doxycycline)
and rifampicin for severe disease
12
13. Antiandrogens
Long-term oral contraceptive pill; antiandrogenic
progesterones drospirenone or cyproterone
acetate may be more effective than standard
combined pills. These are more suitable than
progesterone-only pills or devices.
Spironolactone and finasteride
Response takes 6 months or longer.
13
14. Immunomodulatory treatments for
severe disease
Intralesional corticosteroids into nodules
Systemic corticosteroids short-term for flares
Methotrexate, ciclosporin, and azathioprine
TNFα inhibitors adalimumab and infliximab,
used in higher dose than required for psoriasis,
are the most successful treatments to date. Note
that paradoxically, they may sometimes induce
new-onset hidradenitis suppurativa
14
15. Other medical treatments
Metformin in patients with insulin
resistance
Acitretin (unsuitable for females
of childbearing potential)
Isotretinoin – effective for acne
but appears unhelpful for most
cases of hidradenitis
Colchicine
15
16. Surgical management of hidradenitis
suppurativa
Incision and drainage of acute abscesses
Curettage and deroofing of nodules, abscesses and
sinuses
Laser ablation of nodules, abscesses and sinuses
Wide local excision of persistent nodules
Radical excisional surgery of entire affected areaa
Nd:YAG laser hair removal
16