Hepatobiliary system
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Couinad bismuth system
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TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Cantlies line  line joining IVC
to GB contain middle hepatic V
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Oral cholecystography
• Graham & cole in 1924
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
OCG
• Now has been replaced by USG
• Contrast media used ]
• Ipanoic acid (tele[aque)
• Biloptin
• Solubiloptin
• 2 doses of 3mg dye is given
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Visualisation of GB depends upon
• Ingestion of dye
• Absorption of dye
• Blood flow to liver enterohepatic circulation
• Take up in liver (functional liver)
• Ability of liver to secrete in bile
• Ability of GB to concentrate the excreted dye
• patency of hepatic & cystic duct
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Percutaneous transhepatic cholangiogram
• To diagnose upper CBD
obstruction
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ERCP
• ERCP
• To diagnose lower CBD obstruction
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Nuclear imaging of liver
Hepatobiliary scintigraphy Colloid scintigraphy
HIDA scan
To assess functionjg of hepatocytes & assess
functioning of biliary system
Sulphur colloid scintigraphy
Functioning of Kupffer cells
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HIDA scan
• Uses
• To exclude biliary atresia
• Most accurate investigation for a/c cholecystitis
• IOC is USG
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HIDA scan to detect a/c cholecystitis
• It also used to detect biliary atresia
• Technitium 99 labelled iminodiacetic acid is injected IV
it is picked up by Kupffer cells & excreted in bile
• Helps in clear visualisation of biliary tract
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
ERCP
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ERCP
• To visualise lower CBD
• Biliary & pancreatic system
• Combined endoscopic & radiographic procedure
• Iodinated contrast agents are also used
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MRCP
• Non invasive
• Gadolinium based contrast is not used
• T2 weighted images are used for bile and pancreatic secretions in
biliary tree
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Simple hepatic cyst
• Anechoic /hypoechoic
• With out septa
• Round or ellipsoid
• Absence of its own wall
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Choledochal cyst  modani classification
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Carolis disease  multiple intrahepatic cyts
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Central dot sign in carolis ds
• Enhancing dots with in dilated intrahepatic bile ducts representing
portal radicles
• Portal vein around dilated biliary duct
• Type V
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Cavernous haemangioma
• Mc benign tumour of liver  hemangioma
• Located in postero-superior quadrant of liver of right lobe
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Radiological features of haemangioma
USG • Most of haemangioma are homogenous
echogenicity
• Or may show mixed echogenicity
MRI • Most accurate if lesion <2.5 cm
Hepatic scintigraphy • Accurate if lesion > 2.5 cm
CECT • In arterial phase  enhancement of peripheral
portion of the lesions (ring enhancement / globular
enhancement)
• Centre may remain hypodense
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Light bulb appearance on MRI
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Hyperechoic lesion on USG
Delayed enhancement
of centre
Early enhancement
& rapid wash out
Centripetal homogenous in
case of haemangioma after
initial peripheral nodular
enhancement
Hepatocellular
carcinoma
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TONY SCARIA 2010 KMC
Intrahepatic hydatid cyst
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Intrahepatic hydatid cyst
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Intrahepatic hydatid cyst
• Honey comb appearance
• Floating lily sign
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Porcelain GB can be seen on x ray 
indication for cholecystectomy
• As it is premalignant
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Porcelain GB
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Porcelain GB on CT scan
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Gall stones
• Best detected by USG
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Investigation in gall stones
USG • IOC in case of detection of gall stone & obstructive
jaundice
• WES wall echo shadow
• Double arc shadow sign
Plain X ray • Only 10 % radiopaque
Oral cholecystography • Dye used is ipanoic acid
Cholangiogram • Crescentic shadow or meniscus sign
CT scan • Limited value in gall stones
• Since gall stones have radiographic density as bile
 not detectable by CT
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Double arc sign
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Wall echo shadow sign in c/c contracted GB
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Meniscus sign d/t stone in cholangiogram
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a/c cholecystitis
USG IOC
HIDA scan MOST ACCURATE (non visualisation of GB)
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
TONY SCARIA 2010 KMC
Air in gall stone  triradiate lucency
• Mercedez benz sign
• Sea gull sign
• Crow feet sign
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Mercedez benz sign
• In gall stones
• Star shaped pattern of gas fissuring with in gall stones
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Mercedez benz sign
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Riglers triad in gall stone
Small bowel
obstruction
Ectopic Gall stone
Pneumobilia
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GB adenomayomatosis
• Mc form cholecystoses
• Segmental or diffuse thickening of muscular wall
• In the thickened wall  small cystic spaces are present (Rokitansky
aschoff sinus)
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TONY SCARIA 2010 KMC
GB adenomyomatosis
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Comet tail artefacts in GB adenomyomatosis
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TONY SCARIA 2010 KMC
Cholesterosis
• Deposits of cholesterol
crystals in epithelial cells
& macrophages
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Pneumobilia
• Gall stone erosion & gall stone
ileus
• Infection (emphysematous
cholecystitis)
• Carcinoma of GB
• ERCP & sphincterotomy
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Pneumobilia
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Triangular cord sign
• Biliary atresia on USG of neonate
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TONY SCARIA 2010 KMC
Linear filling defect in ERCP in ascariasis
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• Budd chiari syndrome
• Spider web sign  d/t venous
collaterals
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TONY SCARIA 2010 KMC
Pancreas
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a/c pancreatitis
X ray • Gasless abdomen
• Colon cut off sign
• Sentinal loop sign
• Renal halo sign
CECT • IOC
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Gas less abdomen in pancreatiits
• d/t repeated vomiting & duodenal
spasm
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Sentinel loop sign
• Non specific sign
• Focal dilated proximal jejunal loop in left upper
quadrant
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Renal halo sign in a/c pancreatitis
• d/t pancreatic fluid collection around
kidney
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Colon cut off sign
• d/t spasm  no air in descending colon
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Balthazar CT scoring system in a/c pancreatitis
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c/c pancreatitis
Plain x ray • Multiple calcification across pancreas
Upper GI barium study • Reverse 3 sign in duodenum (similar appearance in
pancreatic carcinoma)
ERCP • IOC
• Chain of lake / string of pearl (d/t fibrosis)
• Rat tail stricture in CBD
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Calcification in region of pancreas in case of
c/c pancreatiitis
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Rat tail stricture of CBD in c/c pancreatitis
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• Chain of lakes appearance in
ERCP is seen is
• Chronic pancreatitis
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c/c pancreatitis
• IOC
• EUS
• MRCP chain of lake appearance
• MDCTintraductal calculus with duct dilation
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Carcinoma pancreas
Double duct sign
Widening of C loop of duodenum
Mucosal irregularity
Rose thorning of medial wall of 2nd part of duodenum d/t puckering of medial wall
Scrambled egg appearance d/t irregularity
Inverse / reverse 3 sign of frostberg
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frostburg inverted 3 sign
• Barium meal
• Effacement & distortion of
mucosal pattern on the medial
wall of 2nd part of duodenum
• Carcinoma head of pancreas
• Duodenum carcinoma
• c/c pancreatitis
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Double duct sign
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Spongy appearance with central sunburst
calcification
• Central sunburst calcification
• With multiple cystic lesion
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• Spongy appearance with central sunburst calcification Serous
cystadenoma
Central sun burst
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• widened duodenal
'C'loop with irregular
mucosal pattern on
upper gastrointestinal
barium series
• Carcinoma head of
pancreas
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Double duct sign
• d/t simultaneous dilation of bile duct & pancreatic duct
• d/t periampullary carcinoma
• Seen in MRI CT ERCP
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• Selenium 75  pancreatic scanning radio isotope used
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Prune tree appearance on ERCP in primary sclerosing cholangitis
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TONY SCARIA 2010 KMC

Hepatobiliary system radiology revision notes