Protein Glycosylation
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Glycosylation, the attachment of sugar moieties to proteins, is a post-translational modification (PTM) that provides greater proteomic diversity than other PTMs.
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Protein Glycosylation
- 5. 3/1/2015 5 Made By: Asmaa Alkhawaga Glycosylation Post-translational modification PTM is the chemical modification of a protein after its translation.
- 6. 3/1/2015 6 Made By: Asmaa Alkhawaga Glycosylation Post-translational modification Acetylation ADP-ribosylation Carboxylation Glycosylation Fatty Acylation Hydroxylation Methylation Phosphorylation Prenylation
- 7. 3/1/2015 7 Made By: Asmaa Alkhawaga Glycosylation Definition enzymes Glycosylation
- 9. 3/1/2015 9 Made By: Asmaa Alkhawaga Glycosylation Definition Glycan and polysaccharide are compounds consisting of a large number of monosaccharaides linked glycosidically.
- 17. 3/1/2015 17 Made By: Asmaa Alkhawaga Glycosylation Definition Aglycosylation, is a feature of engineered antibodies to bypass glycosylation.
- 20. 3/1/2015 20 Made By: Asmaa Alkhawaga Glycosylation Glycoprotein Diversity • It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. Glycosylation increases diversity in the Proteome.
- 22. 3/1/2015 22 Made By: Asmaa Alkhawaga Glycosylation Mechanism The most complex post-translational modification. The donor molecule is often an activated nucleotide sugar. It is a site-specific modification.
- 23. 3/1/2015 23 Made By: Asmaa Alkhawaga Glycosylation Clinical Over 40 disorders of glycosylation have been reported in humans.