Glycolysis is the first stage of carbohydrate catabolism where glucose is oxidized to pyruvic acid in the cytoplasm. The process was described by Embden, Meyerhof and Parnas in 1940 and is known as the Embden-Meyerhof pathway. Glycolysis can occur with or without oxygen present, producing either lactic acid or pyruvate as the end product. It is an important pathway for ATP synthesis in tissues lacking mitochondria and is used by yeast to produce alcohol and lactic acid bacteria to produce lactic acid.

1. GLYCOLYSIS
Presented By
Vigneshwari.D
1stM.sc Microbiology
Sacred Heart College(Autonomous)
Tirupattur Dist,Tamil Nadu,India

2. GLYCOLYSIS
• Glycolysis, the oxidation of Glucose to pyruvic acid,
is usually the first stage in carbhohydrate
catabolism which taks place in Cytoplasm of the
cell.
• The word Glycolysis means splitting og sugar, and
this is exactly what happens (Greek,glycol-sugar;
lysis-loosening).
• Glycolysis pathway was described by Embden,
Meyerhof and Parnas in 1940. Hence, it is also
called as Embdn-Meyerhof pathway

3. • Glycolysis occurs n the absence of oxygen
(Anaerobic) or in the presence of oxygen (Aerobic).
Lactate is the end product under anaerobic
condition. In the Aerobic condition, Pyruvate is
formed, which is then oxidized to CO2 H2O.
• The Glycolysis pathway is operated by Yeast to produce
Alcohol and Lactic acid bacteria to produce Lactic acid
andseveral Organic acids, Fatty acids and Alcohols.
• Glycolysis is a major pathway for ATP synthesis in tissues
lacking Mitochondria.

4. • The enzymes of Glycolyis catalyze the splitting of
Glucose (six-carbon sugar) into two three-carbon
sugars are then oxidized,reeasing energy,and their
atoms are rearranged to form two molecules of
Pyruvic acid.
• During Glycolysis NAD+ is reduced to NADH,and thre is a
net production of two ATP molecules by substrate level
phosphorylation.
• Glycolysis (1 to 4 – Preparatory stage ; 5 to 10 –Energy
conserving stage)