This document discusses gastrointestinal bleeding in children. It defines different types of GI bleeding based on the location such as melena, hematochezia, and hematemesis. Common causes of upper and lower GI bleeding are listed for newborns, infants, children, and adolescents. Evaluation involves history, physical exam, lab tests, and imaging. Treatment depends on the severity and includes supportive care, medications, endoscopic procedures, and surgery. Portal hypertension is described as a cause of GI bleeding along with its pathophysiology, clinical manifestations, diagnosis, and management.
GEMC - Gastrointestinal Bleeding in the Pediatric PatientOpen.Michigan
This is a lecture from the Ghana Emergency Medicine Collaborative (GEMC). To download the editable version (in PPT), to access additional learning modules, or to learn more about the project, see http://openmi.ch/em-gemc. Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Share Alike-3.0 License: http://creativecommons.org/licenses/by-sa/3.0/.
Pancreatitis is an inflammatory condition of the pancreas. Two major forms : acute pancreatitis (is reversible) and chronic pancreatitis(is irreversible).
GEMC - Gastrointestinal Bleeding in the Pediatric PatientOpen.Michigan
This is a lecture from the Ghana Emergency Medicine Collaborative (GEMC). To download the editable version (in PPT), to access additional learning modules, or to learn more about the project, see http://openmi.ch/em-gemc. Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Share Alike-3.0 License: http://creativecommons.org/licenses/by-sa/3.0/.
Pancreatitis is an inflammatory condition of the pancreas. Two major forms : acute pancreatitis (is reversible) and chronic pancreatitis(is irreversible).
constipation in children , pediatric constipation , management of constipation in children , understanding constipation , causes of constipation in children , functional constipation in children , treatment of constipation ,approach to constipation in children ,constipation in infants
Bleeding Per Rectum In Children By Prof. Sushmita N. Bhatnagar MBBS, M.S., M.Ch,M.PHIL(Hospital Management)
HEAD, PEDIATRIC SURGERY
B.J WADIA CHILDREN’S HOSPITAL, MUMBAI
CONSULTANT PEDIATRIC SURGEON
BOMBAY HOSPITAL
JOINT SECRETARY
ASSOCIATION OF MEDICAL CONSULTANTS
For info log on to www.healthlibrary.com.
constipation in children , pediatric constipation , management of constipation in children , understanding constipation , causes of constipation in children , functional constipation in children , treatment of constipation ,approach to constipation in children ,constipation in infants
Bleeding Per Rectum In Children By Prof. Sushmita N. Bhatnagar MBBS, M.S., M.Ch,M.PHIL(Hospital Management)
HEAD, PEDIATRIC SURGERY
B.J WADIA CHILDREN’S HOSPITAL, MUMBAI
CONSULTANT PEDIATRIC SURGEON
BOMBAY HOSPITAL
JOINT SECRETARY
ASSOCIATION OF MEDICAL CONSULTANTS
For info log on to www.healthlibrary.com.
Approach to patient with upper GIT bleeding
Approach to patient with upper GIT bleeding
Approach to patient with upper GIT bleeding
Approach to patient with upper GIT bleeding
Gastrointestinal bleeding (GI bleed), also known as gastrointestinal hemorrhage, is all forms of bleeding in the gastrointestinal tract, from the mouth to the rectum. When there is significant blood loss over a short time, symptoms may include vomiting red blood, vomiting black blood, bloody stool, or black stool.
Approach to Management of Upper Gastrointestinal (GI) BleedingArun Vasireddy
Upper gastrointestinal bleeding is gastrointestinal bleeding in the upper gastrointestinal tract, commonly defined as bleeding arising from the esophagus, stomach, or duodenum. Blood may be observed in vomit (hematemesis) or in altered form in the stool (melena). Depending on the severity of the blood loss, there may be symptoms of insufficient circulating blood volume and shock. As a result, upper gastrointestinal bleeding is considered a medical emergency and typically requires hospital care for urgent diagnosis and treatment. Upper gastrointestinal bleeding can be caused by peptic ulcers, gastric erosions, esophageal varices, and some rarer causes such as gastric cancer.
The initial assessment includes measurement of the blood pressure and heart rate, as well as blood tests to determine hemoglobin concentration. In significant bleeding, fluid replacement is often required, as well as blood transfusion, before the source of bleeding can be determined by endoscopy of the upper digestive tract with an esophagogastroduodenoscopy. Depending on the source, endoscopic therapy can be applied to reduce rebleeding risk. Specific medical treatments (such as proton pump inhibitors for peptic ulcer disease) or procedures (such as TIPS for variceal hemorrhage) may be used. Recurrent or refractory bleeding may lead to need for surgery, although this has become uncommon as a result of improved endoscopic and medical treatment.
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
We understand the unique challenges pickleball players face and are committed to helping you stay healthy and active. In this presentation, we’ll explore the three most common pickleball injuries and provide strategies for prevention and treatment.
QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
2. MELENA: passage of black, tarry stools; suggests
bleeding proximal to the ileocecal valve.
HEMATOCHEZIA: passage of bright or dark red
blood per rectum; indicates colonic source or
massive upper GI bleeding.
HEMATEMESIS: passage of vomited material
that is black (“coffee grounds”) or contains frank
blood; bleeding from above the ligament of Treitz
3. Bleeding proximal to the ligament of Treitz.
◦ Presents with:
Hematemesis .
Melena
If massive then hematochezia.
◦ More blood loss than lower GI bleeding.
4. Bleeding distal to the ligament of Treitz.
◦ Presents with:
Hematochezia – bright red blood per rectum.
Maroon stools – profuse bleed from distal
small bowel
5. Foods: tomatoes, cranberries, Beets ,
red fruit juices and gelatin.
Red-colored medications:
Acetaminophen
Amoxicillin
Spinach, iron, and bismuth
often lead to black stools, which can be confused
with true melena.
6. ◦ Employs a peroxidase-like activity of
hemoglobin to oxidize with the reagent
changing the color to blue.
◦ False positive: red meat, horseradish, turnips,
iron, tomatoes and fresh red cherries.
◦ False negatives: Vitamin C, storage for more
than 4 days or outdated reagents or cards.
7. Swallowed maternal blood -Apt-Downey test
Bleeding mouth lesions.
Nasopharyngeal bleeds.
Pulmonary hemorrhage.
Vaginal bleeding in a newborn.
Münchausen syndrome by proxy.
8. One part of the bloody stool or gastric aspirate is
mixed with 5 parts of water to lyse the red blood
cells.
After the mixture is centrifuged, 1 mL of
0.2 % sodium hydroxide is added to the
supernatant hemoglobin solution.
After2 minutes, fetal hemoglobin, which resists
the alkaline reduction, remains pink, whereas
maternal hemoglobin turns yellow-brown.
14. Goal of history :
GI bleeding or not?
If GI bleed ,then where is the source ?
What is the severity of the blood loss ?
What are the most likely causes?
15. Symptom or sign Location of bleeding lesion
Effortless bright red blood
from mouth
Nasopharyngeal or oral lesions , tonsillitis ,
Esophageal varices
Vomiting of bright red
blood or of coffee
grounds.
Lesion proximal to ligament of treitz
Melena Lesion proximal to ligament of treitz , upper
small bowel .
Blood loss >50 -100 ml /day
Bright red or dark red
blood in stools
Lesion in ileum or colon
Streak of blood on outside
of a stool
Lesion in the rectal ampulla or anal canal
17. CBC, ESR,CRP; PT, PTT in all cases
Others as indicated:
◦ Blood grouping and cross match
◦ AST, ALT, bilirubin
◦ Albumin, total protein
◦ Stool for culture, ova and parasite
examination.
21. Somatostatin : dosage is one to three bolus injections
(250 μg/bolus)during first hour of therapy followed by
infusion of 250μg/hour of continuous infusion for 2–5
days.
Terlipressin : IV injections (2 mg) every 4 hours till
bleeding free interval of 24–48 hours is achieved.
Octreotide : It is a synthetic analog of somatostatin with
half-life of 90 minutes. In children the dose is 1–2 μg/kg
over 2–5 min, then 1–2 μg/kg per hour for 5 days.
22. Balloon tamponade
Endoscopic therapy:
stabilize and prepare patient first
Endoscopic variceal ligation
Endoscopic sclerotherapy :polydocanol, sodium
tetradecylsulfate,
Polypectomy.
A transjugular intrahepatic portosystemic shunt.
Orthotopic liver transplantation represents a much better
therapy for portal hypertension resulting from intrahepatic
disease and cirrhosis.
Long-term treatment with propranolol.
23. Defined as an elevation of portal pressure
>10-12 mm Hg or a hepatic venous pressure
gradient >4 mm Hg.
27. Pathophysiology :
Increased resistance to portal blood flow.
Portosystemic shunting should decompress the portal
system.
development of significant collaterals deviating portal
blood into systemic veins.
A hyperdynamic circulation is achieved by tachycardia,
an increase in cardiac output, decreased systemic
vascular resistance, and increased splanchnic dilation.
Collateral vessels can form prominently in areas in
which absorptive epithelium joins stratified epithelium
Congestive gastropathy
28. Clinical Manifestations :
Bleeding is the most common presentation of portal
hypertension in children.
Splenomegaly is the second most common finding.
Ascites is the presenting sign of portal hypertension
in 7–21% of children.
Hepatopulmonary syndrome (HPS) and
portopulmonary hypertension (PP-HTN)
29. Diagnosis :
patency of the portal vein, and Doppler flow
ultrasonography can demonstrate the direction of
flow within the portal system.
Reversal of portal vein blood flow (hepatofugal flow)
is more likely to be associated with variceal
bleeding.
presence of esophageal varices.
Endoscopy is the most reliable method for
detecting esophageal varices and for identifying the
source of gastrointestinal bleeding.
30. Treatment :
emergency treatment of potentially life-threatening
hemorrhage.
A reasonable goal hemoglobin level after variceal bleed is
between 7 and 9 g/dL.
Correction of coagulopathy by administration of vitamin K
and/or infusion of platelets or fresh-frozen plasma
A nasogastric tube should be placed to document the
presence of blood within the stomach and to monitor for
ongoing bleeding.
An H2 -receptor blocker or proton pump inhibitor should be
given intravenously to reduce the risk of bleeding from
gastric erosions.
Intravenous antibiotics
31. Prognosis :
Portal hypertension is usually progressive and is
often associated with deteriorating liver function.