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Dr M.Sanjeevappa
M.D.(paeds)
Asst.Professor
Dept. of Paediatrics
GMC ,Ananthapuramu
 Brain grossly differentiates into cerebrum
and cerebellum during 1st Trimester of
embryonic life.
 Neurons begin to develop in 2nd trimester.
 By the end of 2nd trimester all neurons are
formed and any damage occurring now is
irreversible.
 Synaptic connections occur in 3rd trimester.
 Cerebral palsy is a chronic neurodevelopmental
disorder.
 never the same disease twice.
 Some children with CP graduate from universities and
become health professionals.
 Some children with CP may be unable to roll or feed
and may be entirely dependent for all activities of daily
living.
 First described in 1862, by William John Little,
an orthopedic surgeon.
 Cerebral Palsy was known as Little’s
Disease for decades.
 The term cerebral Palsy originated with
William Osler and Sigmund Freud.
 Incidence : about 2 per 1000 live births in high
resource settings.
 Cerebral palsy (CP) describes a group of permanent
disorders of movement and posture causing activity
limitation, that are attributed to non progressive
disturbances that occurred in the developing fetal or
immature brain.
 The motor disorders of CP are often accompanied by
disturbances of sensation, perception, cognition,
communication, and behaviour, by epilepsy, and by
secondary musculoskeletal problems.
 Two distinct cohorts of children present with CP.
 Cohort one :
Infants born preterm
Infants born at term experiencing a neonatal
encephalopathy.
 Cohort two:
Developmental surveillance provided through a
community-based workers.
Parental observation of “stiffness” or gait
disturbances.
 Prenatal (44%)
◦ First trimester :
Teratogens.
Chromosomal abnormalities.
Genetic syndromes.
Brain malformations.
◦ Second trimester :
Intrauterine infections.
Problems in fetal/placental functioning
 Labor and delivery (19%)
Preeclampsia.
complications of labor.
 Perinatal (8%)
PREMATURITY
Sepsis/CNS infection,
asphyxia.
 Childhood (5%)
Meningitis.
traumatic brain injury.
toxins.
 Not obvious (24%)
 Spastic : hyper tonicity with poor posture control
 Dyskinetic / athetoid : abnormal involuntary
movement / slow wormlike writhing.
 Ataxic : wide-based gait.
 Mixed-type / dystonic : combination of spasticity
and athetosis
Gross Motor Function Classification System(GMFCS)
Physical signs :
 poor head control after 3 months of age.
 stiff or rigid arms or legs.
 pushing away or arching back.
 floppy or limp body posture.
 cannot sit up without support by 8 months.
 uses only one side of the body, or only the arms to
crawl.
 clenched hands after 3 months(cortical thumb.)
 leg scissoring.
 Seizures.
 sensory impairment (hearing, vision).
 after 6 months of age, persistent tongue thrusting.
 Extreme irritability or crying.
 Feeding difficulties.
 Little interest surrounding.
 Excessive sleeping.
 Stiff or floppy posture.
 Excessive lethargy or irritability /high pitched cry.
 Poor head control.
 Weak suck /tongue thrust /tonic bite /feeding difficulties.
 Persistence of primitive infantile reflexes.
 Intellectual impairment.
 Seizures.
 Drooling of saliva.
 Feeding difficulties.
 Orthopedic complications.
 Dental carries.
 Physical Assessment.
 Observe LBW, preterm, and those with low
Apgar scores at 5 minutes.
 Observe infants who have seizures, intracranial
hemorrhage, metabolic disturbances.
 Diagnosis may not be confirmed until after 6
months of age.
 Magnetic resonance imaging (MRI).
 Ultrasound.
 Computerised tomography (CT) scan.
 Electroencephalogram (EEG).
 Electromyogram (EMG).
 Additional tests: Vision impairment, Hearing
impairment, Speeh impairments, Intellectual
disabilities, Movement disorders
Medical
 To enhance functional abilities of CP child.
 Therapy is chiefly symptomatic and preventive.
The broad aims of therapy are :
 To establish locomotion, communication and self help.
 To gain optimum appearance and integration of motor
functions.
 To correct associated defects as early and effectively .
 To provide educational opportunities adapted to the
individual child’s needs and capabilities.
 To promote socialization experiences with other
affected, unaffected children
 physiotherapy is directed toward good skeletal
alignment for child with spasticity.
 Physiotherapy can help the child's strength,
flexibility, balance, motor development and mobility.
 physiotherapy uses orthotic devices, such as braces,
casting and splints to support and improved walking.
 Using alternative strategies and adaptive
equipment, occupational therapists work to
promote the child's independent participation in
daily activities and routines in the home, the
school and the community.
 Adaptive equipment may include walkers,
quadrupedal canes, seating systems or electric
wheelchairs.
 Speech-language therapist can help improve the
child's ability to speak clearly or to communicate
using sign language.
RECREATION THERAPY
 This therapy can help improve the child's motor
skills, speech and emotional well-being.
 To reduce the effects of cerebral palsy and prevent
complications:
 Analgesic drugs to reduce intense pain or muscle spasm.
 Botulinum toxin type A, used to reduce spasticity in
targeted muscle of the upper and lower extremities.
 Dantrolene sodium, baclofen, and diazepam to improve
muscle coordination and to muscle relaxation.
 Anticonvulsants drug, to relieve or stop seizures
 Surgery used to correct problems with bones
and joints, by lengthening any muscles and
tendons that are too short and causing
problems.
ORTHOPEDIC SURGERY :
 To correct contracture or spastic deformities,
to provide stability for an uncontrolled joint, to
address bone malalignment, and
to provide balanced muscle power.
 Example : tendon transfer, muscle lengthening.
 Selective dorsal rhizotomy (SDR) is a surgical
procedure that can help children with severe
muscle stiffness in their legs to improve their
walking.
 To improve feedings, correct GERD and correct
associated dental problems.
THANK YOU….

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CEREBRAL PALSY

  • 2.  Brain grossly differentiates into cerebrum and cerebellum during 1st Trimester of embryonic life.  Neurons begin to develop in 2nd trimester.  By the end of 2nd trimester all neurons are formed and any damage occurring now is irreversible.  Synaptic connections occur in 3rd trimester.
  • 3.  Cerebral palsy is a chronic neurodevelopmental disorder.  never the same disease twice.  Some children with CP graduate from universities and become health professionals.  Some children with CP may be unable to roll or feed and may be entirely dependent for all activities of daily living.
  • 4.  First described in 1862, by William John Little, an orthopedic surgeon.  Cerebral Palsy was known as Little’s Disease for decades.  The term cerebral Palsy originated with William Osler and Sigmund Freud.  Incidence : about 2 per 1000 live births in high resource settings.
  • 5.  Cerebral palsy (CP) describes a group of permanent disorders of movement and posture causing activity limitation, that are attributed to non progressive disturbances that occurred in the developing fetal or immature brain.  The motor disorders of CP are often accompanied by disturbances of sensation, perception, cognition, communication, and behaviour, by epilepsy, and by secondary musculoskeletal problems.
  • 6.  Two distinct cohorts of children present with CP.  Cohort one : Infants born preterm Infants born at term experiencing a neonatal encephalopathy.  Cohort two: Developmental surveillance provided through a community-based workers. Parental observation of “stiffness” or gait disturbances.
  • 7.  Prenatal (44%) ◦ First trimester : Teratogens. Chromosomal abnormalities. Genetic syndromes. Brain malformations. ◦ Second trimester : Intrauterine infections. Problems in fetal/placental functioning
  • 8.  Labor and delivery (19%) Preeclampsia. complications of labor.  Perinatal (8%) PREMATURITY Sepsis/CNS infection, asphyxia.  Childhood (5%) Meningitis. traumatic brain injury. toxins.  Not obvious (24%)
  • 9.  Spastic : hyper tonicity with poor posture control  Dyskinetic / athetoid : abnormal involuntary movement / slow wormlike writhing.  Ataxic : wide-based gait.  Mixed-type / dystonic : combination of spasticity and athetosis
  • 10.
  • 11. Gross Motor Function Classification System(GMFCS)
  • 12.
  • 13. Physical signs :  poor head control after 3 months of age.  stiff or rigid arms or legs.  pushing away or arching back.  floppy or limp body posture.  cannot sit up without support by 8 months.
  • 14.  uses only one side of the body, or only the arms to crawl.  clenched hands after 3 months(cortical thumb.)  leg scissoring.  Seizures.  sensory impairment (hearing, vision).  after 6 months of age, persistent tongue thrusting.
  • 15.  Extreme irritability or crying.  Feeding difficulties.  Little interest surrounding.  Excessive sleeping.
  • 16.  Stiff or floppy posture.  Excessive lethargy or irritability /high pitched cry.  Poor head control.  Weak suck /tongue thrust /tonic bite /feeding difficulties.  Persistence of primitive infantile reflexes.
  • 17.  Intellectual impairment.  Seizures.  Drooling of saliva.  Feeding difficulties.  Orthopedic complications.  Dental carries.
  • 18.  Physical Assessment.  Observe LBW, preterm, and those with low Apgar scores at 5 minutes.  Observe infants who have seizures, intracranial hemorrhage, metabolic disturbances.  Diagnosis may not be confirmed until after 6 months of age.
  • 19.  Magnetic resonance imaging (MRI).  Ultrasound.  Computerised tomography (CT) scan.  Electroencephalogram (EEG).  Electromyogram (EMG).  Additional tests: Vision impairment, Hearing impairment, Speeh impairments, Intellectual disabilities, Movement disorders
  • 20. Medical  To enhance functional abilities of CP child.  Therapy is chiefly symptomatic and preventive. The broad aims of therapy are :  To establish locomotion, communication and self help.  To gain optimum appearance and integration of motor functions.  To correct associated defects as early and effectively .  To provide educational opportunities adapted to the individual child’s needs and capabilities.  To promote socialization experiences with other affected, unaffected children
  • 21.  physiotherapy is directed toward good skeletal alignment for child with spasticity.  Physiotherapy can help the child's strength, flexibility, balance, motor development and mobility.  physiotherapy uses orthotic devices, such as braces, casting and splints to support and improved walking.
  • 22.
  • 23.  Using alternative strategies and adaptive equipment, occupational therapists work to promote the child's independent participation in daily activities and routines in the home, the school and the community.  Adaptive equipment may include walkers, quadrupedal canes, seating systems or electric wheelchairs.
  • 24.
  • 25.  Speech-language therapist can help improve the child's ability to speak clearly or to communicate using sign language. RECREATION THERAPY  This therapy can help improve the child's motor skills, speech and emotional well-being.
  • 26.  To reduce the effects of cerebral palsy and prevent complications:  Analgesic drugs to reduce intense pain or muscle spasm.  Botulinum toxin type A, used to reduce spasticity in targeted muscle of the upper and lower extremities.  Dantrolene sodium, baclofen, and diazepam to improve muscle coordination and to muscle relaxation.  Anticonvulsants drug, to relieve or stop seizures
  • 27.  Surgery used to correct problems with bones and joints, by lengthening any muscles and tendons that are too short and causing problems. ORTHOPEDIC SURGERY :  To correct contracture or spastic deformities, to provide stability for an uncontrolled joint, to address bone malalignment, and to provide balanced muscle power.  Example : tendon transfer, muscle lengthening.
  • 28.  Selective dorsal rhizotomy (SDR) is a surgical procedure that can help children with severe muscle stiffness in their legs to improve their walking.
  • 29.
  • 30.  To improve feedings, correct GERD and correct associated dental problems.
  • 31.