Generic Zantac for Treatment of Duodenal and Gastric Ulcers

Generic Zantac Tablets
Generic Zantac (Zinetac Tablets) is used in
treatment of peptic ulcers (gastric and duodenal
ulcers), reflux oesophagitis (reflux disease),
Zollinger-Ellison syndrome and scleroderma
oesophagitis and to prevent duodenal ulcers and
reflux disease from recurring.
© The Swiss Pharmacy, Geneva Switzerland

Generic Zantac (Zinetac Tablets) is
available in strengths of 150 mg and 300
mg.
Each Generic Zantac 150 Tablet for oral
administration contains 168 mg of
Ranitidine HCl equivalent to 150 mg of
Ranitidine.

Chemical Structure

Active Ingredient
The active pharmaceutical ingredient present
in Generic Zantac Tablets is Ranitidine
Hydrochloride. Ranitidine Hydrochloride
is a white to pale yellow, granular
substance that is soluble in water.

Indications
Generic Zantac Tablets are used for the
treatment of duodenal ulcer and benign
gastric ulcer. Ranitidine HCl Tablets are
also used for the:
Treatment of post-operative ulcer
Symptom relief in gastro-oesophageal
reflux disease
Treatment of oesophageal reflux disease

Indications
Treatment of duodenal ulcer and benign
gastric ulcer associated with non-steroidal
anti-inflammatory agents.
Prevention of non-steroidal anti-inflammatory
agent (including aspirin) associated duodenal
ulcers in patients with a history of duodenal
ulceration proven by endoscopy.

Indications
Treatment of chronic episodic dyspepsia,
characterised by pain (epigastric or
retrosternal) which is related to meals or
disturbs sleep but not associated with the
above conditions.
Treatment of Zollinger-Ellison syndrome

Indications
Generic Zantac (Zinetac Tablets) are also
indicated for the following conditions where
reduction of gastric secretion and acid output
is desirable:
The prevention of upper gastrointestinal
haemorrhage from stress ulceration in
seriously ill patients.
The prevention of recurrent haemorrhage in
patients with bleeding peptic ulcers.

Indications
Before general anaesthesia in patients
considered to be at risk of acid
aspiration (Mendelson's syndrome),
particularly obstetric patients during
labour.

Recommended Adult Dosage
Active Duodenal Ulcer:
The recommended adult oral dosage of
Generic Zantac for duodenal ulcer is 150 mg
twice daily.
Maintenance of Healing of Duodenal
Ulcers:
The current recommended adult oral dosage
is 150 mg at bedtime.

Pathological Hypersecretory Conditions
(such as Zollinger-Ellison syndrome):
is 150 mg twice daily.
Benign Gastric Ulcer:
Maintenance of Healing of Gastric Ulcers:
is 150 mg at bedtime.

GERD:
Erosive Esophagitis:
is 150 mg or 10 mL of syrup 4 times daily.
Maintenance of Healing of Erosive
Esophagitis:

Missed Dose
If you miss a dose, take it as soon as
you remember.
However, if you remember when it is
almost time for your next dose, take
only your usual dose at that time.

Contraindications
Generic Zantac Tablets are
contraindicated in the following
cases:
➔Known hypersensitivity to Ranitidine
Hydrochloride or any inactive
ingredients of this medication.

Side Effects of Generic Zantac Tablets
Headache, malaise, dizziness,
somnolence, insomnia, and vertigo.
Rare cases of reversible mental
confusion, agitation, depression, and
hallucinations have been reported.
Rare reports of arrhythmias such as
tachycardia, bradycardia, atrioventricular
block, and premature ventricular beats.

Constipation, diarrhea, nausea/vomiting,
abdominal discomfort/pain, and rare
reports of pancreatitis.
Occasional reports of hepatocellular,
cholestatic, or mixed hepatitis, with or
without jaundice.
Rare reports of arthralgias and myalgias.

Blood count changes (leukopenia,
granulocytopenia, and
thrombocytopenia) have occurred in a
few patients.
Rare cases of breast symptoms and
conditions, including galactorrhea and
gynecomastia, have been reported in
both males and females.

Rare cases of hypersensitivity reactions
(e.g., bronchospasm, fever, rash,
eosinophilia), anaphylaxis, angioneurotic
edema, acute interstitial nephritis, and
small increases in serum creatinine.

Warnings And Precautions
➔Symptomatic response to therapy with Generic
Zantac does not preclude the presence of gastric
malignancy.
➔Since Generic Zantac is excreted primarily by the
kidney, dosage should be adjusted in patients with
impaired renal function. Caution should be observed
in patients with hepatic dysfunction since Zantac is
metabolized in the liver.
➔Rare reports suggest that Generic Zantac may
precipitate acute porphyric attacks in patients with
acute porphyria. Zinetac tablets should therefore be
avoided in patients with a history of acute porphyria.

Overdosage Symptoms
Acute ingestions of up to 18 g of
Zantac orally have been associated
with transient adverse effects similar to
those encountered in normal clinical
experience. In addition, abnormalities
of gait and hypotension have been
reported.

Overdose Treatment
Should Zantac overdose occur, the
usual measures to remove
unabsorbed material from the
gastrointestinal tract, clinical
monitoring, and supportive therapy
should be employed.

Storage Instructions
Store between 15° and 30°C (59° and
86°F) in a dry place. Protect from light.
Keep away from children and pets.

Zinetac Tablets Manufactured by
GlaxoSmithKline India
For more information click here

Generic Zantac for Treatment of Duodenal and Gastric Ulcers

Recommended

Recommended

More Related Content

What's hot

What's hot (18)

Viewers also liked

Viewers also liked (13)

Similar to Generic Zantac for Treatment of Duodenal and Gastric Ulcers

Similar to Generic Zantac for Treatment of Duodenal and Gastric Ulcers (20)

More from The Swiss Pharmacy

More from The Swiss Pharmacy (20)

Recently uploaded

Recently uploaded (20)

Generic Zantac for Treatment of Duodenal and Gastric Ulcers