Cardiovascular safety of anti-diabetic drugs.Cardiovascular Outcome Trials ...magdy elmasry
Cardiologists and diabetes.Target organs and action mechanism of antidiabetic drugs.Cardiovascular Outcome Trials
( CVOTs ) in Diabetes.Completed and ongoing CVOTs in type 2 diabetes.Diabetes Medications
and
Cardiovascular Impact.Recommendations for management of diabetes
Cardiovascular safety of anti-diabetic drugs.
Cardiovascular safety of anti-diabetic drugs.Cardiovascular Outcome Trials ...magdy elmasry
Cardiologists and diabetes.Target organs and action mechanism of antidiabetic drugs.Cardiovascular Outcome Trials
( CVOTs ) in Diabetes.Completed and ongoing CVOTs in type 2 diabetes.Diabetes Medications
and
Cardiovascular Impact.Recommendations for management of diabetes
Cardiovascular safety of anti-diabetic drugs.
VILDAGLIPTIN: DPP-IV INHIBITOR
Generic name: Vildagliptin
Brand name: Galvus
Treatment for: type 2 diabetes
selective inhibitor of dipeptidyl-
peptidase IV (DPP-IV)
- the first in a new class of oral antidiabetic agents
- known as dipeptidyl peptidase IV inhibitors
(DPP-IV) inhibitors
SGLT2 Inhibitors (Gliflozins): A New Class of Drugs to treat Type 2 Diabetes:Naina Mohamed, PhD
Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors such as Dapagliflozin (Farxiga), Canagliflozin (Invokana) and Empagliflozin (Jardiance) are a new class of oral drugs available to treat type 2 diabetes mellitus (Type 2 DM).
Jardiance (Empagliflozin tablets) is used to treat adults with type 2 diabetes mellitus to improve glycaemic control. It is used as monotherapy when diet and exercise alone do not provide adequate glycaemic control in patients for whom use of Metformin is considered inappropriate due to intolerance. This medicine is also used in combination with other glucose-lowering medicines such as insulin, when these, combined with diet and exercise, do not provide adequate glycaemic control.
It is also used to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease.
Aldactone (Spironolactone Tablets) is used to treat fluid retention (edema) caused by various conditions, including heart disease, cirrhosis of the liver and nephrotic syndrome; High blood pressure; Hyperaldosteronism ( a condition in which the body produces too much aldoterone, a naturally occurring hormone) and low potassium levels in the blood (hypokalemia).
VILDAGLIPTIN: DPP-IV INHIBITOR
Generic name: Vildagliptin
Brand name: Galvus
Treatment for: type 2 diabetes
selective inhibitor of dipeptidyl-
peptidase IV (DPP-IV)
- the first in a new class of oral antidiabetic agents
- known as dipeptidyl peptidase IV inhibitors
(DPP-IV) inhibitors
SGLT2 Inhibitors (Gliflozins): A New Class of Drugs to treat Type 2 Diabetes:Naina Mohamed, PhD
Sodium-Glucose Linked Transporter 2 (SGLT2) inhibitors such as Dapagliflozin (Farxiga), Canagliflozin (Invokana) and Empagliflozin (Jardiance) are a new class of oral drugs available to treat type 2 diabetes mellitus (Type 2 DM).
Jardiance (Empagliflozin tablets) is used to treat adults with type 2 diabetes mellitus to improve glycaemic control. It is used as monotherapy when diet and exercise alone do not provide adequate glycaemic control in patients for whom use of Metformin is considered inappropriate due to intolerance. This medicine is also used in combination with other glucose-lowering medicines such as insulin, when these, combined with diet and exercise, do not provide adequate glycaemic control.
It is also used to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and established cardiovascular disease.
Aldactone (Spironolactone Tablets) is used to treat fluid retention (edema) caused by various conditions, including heart disease, cirrhosis of the liver and nephrotic syndrome; High blood pressure; Hyperaldosteronism ( a condition in which the body produces too much aldoterone, a naturally occurring hormone) and low potassium levels in the blood (hypokalemia).
Glimepiride Tablets USP Taj Pharma SmPCTajPharmaQC
Glimepiride Tablets USP 1mg, 2mg, 3mg, 4mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Glimepiride Dosage & Rx Info | Glimepiride Uses, Side Effects Glimepiride: Indications, Side Effects, Warnings, Glimepiride-Drug Information –Taj Pharma, Glimepiride dose Taj pharmaceuticals Glimepiride interactions, Taj Pharmaceutical Glimepiride contraindications, Glimepiride price, Glimepiride Taj Pharma Glimepiride SmPC- Taj Pharma Stay connected to all updated on Glimepiride Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Pioglitazone Hydrochloride Tablets (P-Glitz) are used along with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Pancreas makes a hormone called insulin. It helps your cells turn glucose, a type of sugar, from the food you eat into energy. Diabetes happens when one or more of the following occurs:
Your pancreas does not make any insulin.
Your pancreas makes very little insulin.
Your body does not respond the way it should to insulin
Janumet (Sitagliptin and Metformin Tablets) helps to lower blood sugar levels in patients with type 2 diabetes mellitus along with diet and exercise and possibly with other medications.
Generic Selegiline HCl Tablets (Selgin) is used to treat movement disorders caused by Parkinson's disease. Selgin does not cure Parkinson's disease, but it may improve shakiness (tremor), muscle stiffness, loss of normal movement as your dose of other Parkinson's medication wears off, and sudden changing between normal movement and stiffness ("on-off" problems).
Treat Hypertension with Generic Amlodipine Besylate Tablets The Swiss Pharmacy
Generic Amlodipine Besylate Tablets is used to treat high blood pressure (hypertension) by itself or together with other medicines.
Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Amlodipine is also used to relieve chronic stable angina (chest pain) in adults.
Generic Amlodipine could help to increase the ability to exercise and decrease the frequency of angina attacks.
Generic Fenofibrate Tablets (Fenolip, Lipicard, Tgr) are used as an adjunct to diet and other non-pharmacological treatment (e.g. exercise, weight reduction) for treatment of severe hypertriglyceridaemia with or without low HDL cholesterol, mixed hyperlipidaemia when a statin is contraindicated or not tolerated and mixed hyperlipidaemia in patients at high cardiovascular risk in addition to a statin when triglycerides and HDL cholesterol are not adequately controlled.
introduction to oral hypoglycemic agents with description about sulphonylurea and glinides along with their MOA, indication, side effects and brand name
Type 2 dm gdm new updates & guidelinesSachin Verma
Type 2 diabetes is a multifactorial disorder characterised by progressive pancreatic beta-cell dysfunction and insulin- resistance, leading to relative insulin deficiency, chronic hyperglycaemia, and various complications.
The treatment options for this disorder, which aim at correcting one or other of the two major pathophysiological mechanisms, have been hamstrung by unacceptable side-effects, lack of patient acceptability, and loss of efficacy over time.
TGR (Generic Fenofibrate Tablets) is a peroxisome proliferator receptor alpha (PPARa) activator which is used as adjunctive therapy to diet to lower the amount of low-density lipoprotein cholesterol (LDL-C), total cholesterol (Total-C), Triglycerides and apolipoprotein B (Apo B), and to increase high-density lipoprotein cholesterol (HDL-C) in adult patients with primary hypercholesterolemia or mixed dyslipidemia.
TGR tablets are also used as adjunctive therapy to diet for treatment of adult patients with severe hypertriglyceridemia.
Divaine Tablets by Cipla (Generic Minocycline Hydrochloride Tablets)Clearsky Pharmacy
Divaine (Generic Minocycline Hydrochloride Tablets) is used to treat the following infections due to susceptible microorganisms: acne, gonorrhoea, non-gonococcal urethritis, syphilis, prostatitis, acute and chronic bronchitis, bronchiectasis, lung abscess, pneumonia, ear, nose and throat infections, urinary tract infections, pelvic inflammatory disease, skin and soft tissue infections, ophthalmological infections, nocardiosis, prophylactic treatment of asymptomatic meningococcal carriers, pre- and post-operative prophylaxis of infection, trachoma, and inclusion conjunctivitis.
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)Clearsky Pharmacy
Ciplactin (Generic Cyproheptadine Hydrochloride Tablets) are used as a therapy for Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis due to inhalant allergens and foods, Mild, uncomplicated allergic skin manifestations of urticaria and angio-oedema, Amelioration of allergic reactions to blood or plasma, Cold urticaria and Dermatographism.
Ciplactin is also used as a therapy for anaphylactic reactions adjunctive to Epinephrine and other standard measures after the acute manifestations have been controlled.
Ciplactin tablets are also used to stimulate the appetite and may lead to weight gain, which is helpful for underweight people who wish to gain weight.
Asthalin Tablets by Cipla (Generic Albuterol Sulphate Tablets)Clearsky Pharmacy
Asthalin Tablets (Generic Albuterol Sulphate Tablets) belongs to the group of medicines known as short acting beta2-adrenergic agonist. Asthalin tablets (Salbutamol Sulphate tablets) are used for the treatment of bronchospasm in asthma, chronic bronchitis, emphysema and other conditions associated with airways obstruction, for prevention of asthma attack triggered by allergic exposure or exercise and chronic obstructive pulmonary disease.
Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that open up the bronchial tubes (air passages) in the lungs, thus making breathing easier. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.
Clopivas Tablets by Cipla (Generic Clopidogrel Bisulfate Tablets)Clearsky Pharmacy
Clopivas (Generic Clopidogrel Bisulfate Tablets) is a platelet inhibitor and prevent blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It used to treat patients with Acute coronary syndrome (unstable angina (UA)/non-ST-segment elevation ACS (NSTEMI)& ST-elevation myocardial infarction (STEMI) ), recent myocardial infarction (MI), recent stroke, or established peripheral arterial disease.
Aromex Tablets by Alpha Pharma (Generic Exemestane Tablets)Clearsky Pharmacy
Aromex (Generic Exemestane Tablets) is used to treat hormone dependent early breast cancer in postmenopausal women after they have completed 2 to 3 years of treatment with the medicine Tamoxifen.
Ciplox Tablets by Cipla (Generic Ciprofloxacin Hydrochloride Tablets)Clearsky Pharmacy
Ciplox (Generic Ciprofloxacin Hydrochloride Tablets) is a broad spectrum Fluoroquinolone antibacterial indicated in adults 18 years of age or more with the following infections caused by designated, susceptible bacteria and in pediatric patients where indicated: Skin and Skin Structure Infections, Bone and Joint Infections, Complicated Intra-Abdominal Infections, Infectious Diarrhea, Typhoid Fever (Enteric Fever), Uncomplicated Cervical and Urethral Gonorrhea, Inhalational Anthrax post-exposure in adult and pediatric patients, Plague in adult and pediatric patients, Chronic Bacterial Prostatitis, Lower Respiratory Tract Infections, Acute Exacerbation of Chronic Bronchitis, Urinary Tract Infections, Urinary Tract Infections
(UTI), Acute Uncomplicated Cystitis, Complicated UTI and Pyelonephritis in Pediatric Patients and Acute Sinusitis.
Primox Tablets by Sun (Generic Nortriptyline Hydrochloride Tablets)Clearsky Pharmacy
Primox (Generic Nortriptyline Hydrochloride Tablets) is used for the relief of symptoms of depression. It may also be used for the treatment of some cases of nocturnal enuresis. It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals in the brain.
Budecort Rotacaps by Cipla (Generic Budesonide Inhalation Powder)Clearsky Pharmacy
Budecort Rotacaps (Generic Budesonide Inhalation Powder) are used for the maintenance treatment of asthma as prophylactic therapy in adult and pediatric patients five years of age or older. It is also used for patients requiring oral corticosteroid therapy for asthma. Many of those patients may be able to reduce or eliminate their requirement for oral corticosteroids over time.
Budecort Rotacaps are not used for the relief of acute bronchospasm.
Asthalin Inhaler by Cipla (Generic Albuterol Sulfate Inhaler)Clearsky Pharmacy
Asthalin Inhaler (Generic Albuterol Sulfate Inhaler) is a beta2-adrenergic agonist used for the treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease. It is also used for the prevention of exercise-induced bronchospasm in patients 4 years of age and older.
Letromina Tablets by Alpha-pharma (Generic Letrozole Tablets)Clearsky Pharmacy
Letromina Tablets (Generic Letrozole Tablets) are used for the adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. Letromina is used for the extended adjuvant treatment of early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy. This medicine is also indicated for first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancer.
Letromina (Generic Letrozole) is also used for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Letrozole (Letromina Tablets ) has also been used off-label for more than 15 years to treat infertility in women with PCOS.
Kenacort Injection by Abbott(Generic Triamcinolone Acetonide Injectable Suspe...Clearsky Pharmacy
Kenacort Injection (Generic Triamcinolone Acetonide Injectable Suspension), a corticosteroid hormone (glucocorticoid), is used to treat variety of conditions such as allergic disorders, arthritis, blood diseases, breathing problems, certain cancers, eye diseases, intestinal problems, collagen and skin diseases.
Discuss with your doctor about the risks and benefits of Triamcinolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use.
Astralean (Generic Clenbuterol Hydrochloride Tablets) is used to treat breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator in order to make breathing easier.
Betnovate Cream (Generic Betamethasone Valerate Cream) belongs to a group of medicines known as corticosteroids, and is used to treat various inflammatory skin conditions, including eczema, psoriasis, dermatitis, insect bites and prickly heat.
Betamethasone Valerate Cream works by reducing the inflammation in the affected area to reduce the redness, swelling and itchiness of the skin.
Lan capsules (Generic Lansoprazole capsules) is an effective medication which inhibits the stomach's production of acid. It is used for the Treatment of duodenal and gastric ulcer, Treatment of reflux oesophagitis, Prophylaxis of reflux oesophagitis, Eradication of Helicobacter pylori (H. pylori) concurrently given with appropriate antibiotic therapy for treatment of H.pylori-associated ulcers, Treatment of NSAID-associated benign gastric and duodenal ulcers in patients requiring continued NSAID treatment, Prophylaxis of NSAID-associated gastric ulcers and duodenal ulcers in patients at risk requiring continued therapy, Symptomatic Gastroesophageal Reflux Disease (GERD) and Zollinger-Ellison Syndrome.
Ovral-L Tablets (Generic Levonorgestrel and Ethinyl Estradiol Tablets)Clearsky Pharmacy
Ovral-L Tablets (Generic Levonorgestrel and Ethinyl Estradiol Tablets) is a combination hormone medicine which is indicated for use by females of reproductive potential for prevention of pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization (pregnancy) is prevented. It is also used for the treatment of moderate acne vulgaris in women more than 14 years of age who, have no known contraindications to oral contraceptive therapy, desire contraception, and have achieved menarche.
Budecort Inhaler (Generic Budesonide Inhaler) is used for the maintenance treatment of asthma as prophylactic therapy in adult and pediatric patients. It is also indicated for patients requiring oral corticosteroid therapy for asthma. Many of those patients may be able to reduce or eliminate their requirement for oral corticosteroids over time.
Budecort Inhaler is not indicated for the relief of acute bronchospasm.
Rostar (Generic Rosuvastatin Calcium Tablets) is an HMG Co-A reductase inhibitor used to treat patients with hypertriglyceridemia as an adjunct to diet, patients with primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) as an along with a suitable diet and patients with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C, total-C, and ApoB.
Major Depressive Disorder (MDD) Symptoms and TreatmentsClearsky Pharmacy
Major Depressive Disorder (MDD) or clinical depression, is a mood disorder that causes a persistent feeling of sadness and loss of interest. In case you feel depressed, make an appointment to see your doctor or mental health professional as soon as you can.
Major depressive disorder is a medical condition with treatment available. Treatments include Talk therapy, Cognitive behavioural therapy, Interpersonal psychotherapy, Solution-focused therapy, Reducing stress as well as medications.
Valclovir Tablets (Generic Valacyclovir Hydrochloride 500 mg and 1000 mg Tablets) belongs to a group of medications called antivirals. Valclovir can be used to: treat shingles (in adults), treat HSV infections of the skin and genital herpes (in adults and adolescents over 12 years old). It is also used to help prevent these infections from returning. Generic Valacyclovir tablets is also used to treat cold sores (in adults and adolescents over 12 years old), prevent infection with CMV after organ transplants (in adults and adolescents over 12 years old) and treat and prevent HSV infections of the eye that continue to come back (in adults and adolescents over 12 years old). This medicine works by killing or stopping the growth of viruses called herpes simplex (HSV), varicella zoster (VZV) and cytomegalovirus (CMV).
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.