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THE FIRST NATIONAL BIOTECHNOLOGY AWARENESS ORGANIZATION
WWW.BIOTEAMEGY.COM | INFO@BIOTEAMEGY.COM
BioTeamEgy
SPONSORED BY
TAHA AHMED TAHA
Founder of Bio Team Egypt | taha.ahmed@bioteamegy.com
TahaTaha6
Gene
Mapping
A New Biotechnology Era Ahead
• What Is Maps?
A map is a symbolic depiction emphasizing relationships
between elements of some space, such as objects, regions, or
themes.
• What Is Maps?
A map is a symbolic depiction emphasizing relationships
between elements of some space, such as objects, regions, or
themes.
But Why?
• That’s Why We Use It!
In most cases to help us plan a particular activity.
It’s Not A
Geography
Class!
• Human Made Human Map!
Human
Genome
Project
2003
• Human Genome Project
In April 2003, researchers successfully completed the Human Genome
Project, under budget and more than two years ahead of schedule.
There are between 30,000 and 40,000 genes in the human genome.
The Human Genome Project has already fueled the discovery of more than
1,800 disease genes.
There are now more than 2,000 genetic tests for human conditions. These
tests enable patients to learn their genetic risks for disease and also help
healthcare professionals to diagnose disease.
As a result of the Human Genome Project, today’s researchers can find a
gene suspected of causing an inherited disease in a matter of days, rather
than the years it took before the genome sequence was in hand.
At least 350 biotechnology-based products resulting from the Human
Genome Project are currently in clinical trials.
The Human Genome
Project has already fueled
the discovery of more
than 1,800 disease genes.
Gene Mapping!
Gene Mapping describes the methods used to identify the locus
of a gene and the distances between genes.
• Methods of Gene Mapping!
Genetic Map
Cytogenetic
Map
Physical Map
 Gene maps help describe
the spatial arrangement of
genes on a chromosome.
Genes are designated to a
specific location on a
chromosome known as the
locus and can be used as
molecular markers to find the
distance between other
on a chromosome.
• Genetic Map (Genetic-Linkage Mapping):
 Traits that are inherited together most often are probably influenced by
genes that are close to each other on a chromosome. On the other
hand, traits that are inherited together less often are probably
influenced by genes that are farther apart.
 By following several traits through generations and recording how
often recombinants occur, one can map the relative position of
corresponding genes.
 Today, scientists make genetic-linkage maps by tracing the inheritance
of certain DNA sequences. These sequence variations, or
polymorphisms, make up many of the landmarks on modern genetic-
linkage maps and enable scientists to anchor genes to their true
physical locations in the genome.
• Genetic Map  One can map the relative position of corresponding genes.
• Cytogenetic Map:
 A cytogenetic map is the visual appearance of
a chromosome when stained and examined
under a microscope. Particularly important are
visually distinct regions, called light and dark
bands, which give each of the chromosomes a
unique appearance. This feature allows a
person's chromosomes to be studied in a
clinical test known as a karyotype.
 Karyotype• Cytogenetic Map:
• Physical Map:
Restriction
Mapping
1
Fluorescent in situ
Hybridization
(FISH)
2
Sequence Tagged
Site (STS)
Mapping
3
• Physical Map:
 A physical map provides detail of the actual physical
distance between genetic markers, as well as the number of
nucleotides.
• Applications of Gene Mapping:
Medicine
1
Agricultural
2
Energy
3
Forensics
4
Environment
5
Biotechnology!
• References:
 https://en.wikipedia.org/wiki/Gene_map
 https://en.wikipedia.org/wiki/Genetic_linkage
 https://www.genome.gov/10000715/genetic-mapping-fact-sheet/
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475727/
 https://www.ncbi.nlm.nih.gov/Class/MLACourse/Original8Hour/Genetics/cytogenetic.html
 http://www.els.net/WileyCDA/ElsArticle/refId-a0000819.html
 http://www.genomenewsnetwork.org/resources/whats_a_genome/Chp3_2.shtml
 https://sciencing.com/difference-between-linkage-mapping-chromosome-mapping-16804.html
 https://en.wikipedia.org/wiki/Gene_mapping
 https://report.nih.gov/NIHfactsheets/ViewFactSheet.aspx?csid=45
 https://www.genome.gov/images/content/geneticmapping_factsheet.jpg
 https://www.mun.ca/biology/scarr/Human_Karyotype.html
 https://courses.lumenlearning.com/boundless-biology/chapter/mapping-genomes/
 http://learn.genetics.utah.edu/content/cotton/physical/
 http://geneticmap.net/benefits.php
Taha Ahmed Taha
Founder of Bio Team Egypt | tahataha71@gmail.com
Taha Taha
Thank You!

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Gene Mapping

  • 1. THE FIRST NATIONAL BIOTECHNOLOGY AWARENESS ORGANIZATION WWW.BIOTEAMEGY.COM | INFO@BIOTEAMEGY.COM BioTeamEgy SPONSORED BY
  • 2. TAHA AHMED TAHA Founder of Bio Team Egypt | taha.ahmed@bioteamegy.com TahaTaha6
  • 4. • What Is Maps? A map is a symbolic depiction emphasizing relationships between elements of some space, such as objects, regions, or themes.
  • 5. • What Is Maps? A map is a symbolic depiction emphasizing relationships between elements of some space, such as objects, regions, or themes. But Why?
  • 6. • That’s Why We Use It! In most cases to help us plan a particular activity.
  • 8. • Human Made Human Map!
  • 10. • Human Genome Project In April 2003, researchers successfully completed the Human Genome Project, under budget and more than two years ahead of schedule. There are between 30,000 and 40,000 genes in the human genome. The Human Genome Project has already fueled the discovery of more than 1,800 disease genes. There are now more than 2,000 genetic tests for human conditions. These tests enable patients to learn their genetic risks for disease and also help healthcare professionals to diagnose disease. As a result of the Human Genome Project, today’s researchers can find a gene suspected of causing an inherited disease in a matter of days, rather than the years it took before the genome sequence was in hand. At least 350 biotechnology-based products resulting from the Human Genome Project are currently in clinical trials.
  • 11. The Human Genome Project has already fueled the discovery of more than 1,800 disease genes.
  • 13. Gene Mapping describes the methods used to identify the locus of a gene and the distances between genes.
  • 14. • Methods of Gene Mapping! Genetic Map Cytogenetic Map Physical Map
  • 15.  Gene maps help describe the spatial arrangement of genes on a chromosome. Genes are designated to a specific location on a chromosome known as the locus and can be used as molecular markers to find the distance between other on a chromosome.
  • 16. • Genetic Map (Genetic-Linkage Mapping):  Traits that are inherited together most often are probably influenced by genes that are close to each other on a chromosome. On the other hand, traits that are inherited together less often are probably influenced by genes that are farther apart.  By following several traits through generations and recording how often recombinants occur, one can map the relative position of corresponding genes.  Today, scientists make genetic-linkage maps by tracing the inheritance of certain DNA sequences. These sequence variations, or polymorphisms, make up many of the landmarks on modern genetic- linkage maps and enable scientists to anchor genes to their true physical locations in the genome.
  • 17. • Genetic Map  One can map the relative position of corresponding genes.
  • 18. • Cytogenetic Map:  A cytogenetic map is the visual appearance of a chromosome when stained and examined under a microscope. Particularly important are visually distinct regions, called light and dark bands, which give each of the chromosomes a unique appearance. This feature allows a person's chromosomes to be studied in a clinical test known as a karyotype.
  • 20. • Physical Map: Restriction Mapping 1 Fluorescent in situ Hybridization (FISH) 2 Sequence Tagged Site (STS) Mapping 3
  • 21. • Physical Map:  A physical map provides detail of the actual physical distance between genetic markers, as well as the number of nucleotides.
  • 22. • Applications of Gene Mapping: Medicine 1 Agricultural 2 Energy 3 Forensics 4 Environment 5
  • 24. • References:  https://en.wikipedia.org/wiki/Gene_map  https://en.wikipedia.org/wiki/Genetic_linkage  https://www.genome.gov/10000715/genetic-mapping-fact-sheet/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475727/  https://www.ncbi.nlm.nih.gov/Class/MLACourse/Original8Hour/Genetics/cytogenetic.html  http://www.els.net/WileyCDA/ElsArticle/refId-a0000819.html  http://www.genomenewsnetwork.org/resources/whats_a_genome/Chp3_2.shtml  https://sciencing.com/difference-between-linkage-mapping-chromosome-mapping-16804.html  https://en.wikipedia.org/wiki/Gene_mapping  https://report.nih.gov/NIHfactsheets/ViewFactSheet.aspx?csid=45  https://www.genome.gov/images/content/geneticmapping_factsheet.jpg  https://www.mun.ca/biology/scarr/Human_Karyotype.html  https://courses.lumenlearning.com/boundless-biology/chapter/mapping-genomes/  http://learn.genetics.utah.edu/content/cotton/physical/  http://geneticmap.net/benefits.php
  • 25. Taha Ahmed Taha Founder of Bio Team Egypt | tahataha71@gmail.com Taha Taha Thank You!