Guillain-Barré syndrome is a disorder where the immune system attacks the peripheral nervous system, damaging nerves and causing tingling, muscle weakness, and paralysis. It occurs in about 1 in 100,000 people and most often between ages 30-50. While it can occur at any age, it is rare in children under 2. Guillain-Barré syndrome may be triggered by viral infections and results in loss of reflexes and muscle function. Diagnosis involves neurological exams, spinal fluid tests, and electrodiagnostic tests like electromyography. Treatment focuses on reducing symptoms through antibiotics, analgesics, plasmapheresis, and immunoglobulin therapy to speed recovery.

2.  Guillain-Barré syndrome is a disorder in
which the body's immune system attacks part
of the peripheral nervous system
 Guillain-Barre syndrome damages parts of
nerves. This nerve damage causes
tingling, muscle weakness, and paralysis.
Guillain-Barre syndrome most often affects
the nerve's covering (myelin sheath). Such
damage is called demyelination, and it
causes nerve signals to move more slowly.

3.  Guillain-Barré
is a very rare condition that
occures in about one person out of 100,00.
 The syndrome may occur at any age, but is
most common in people of both sexes
between ages 30 and 50.
 This syndrome can occur at any age, but is
rare in children under age 2.

4.  Guillain-Barre syndrome may occur along
with viral infections such as:
 AIDS
 Herpes simplex
 a bacterial infection

5.  Loss of reflexes in the arms and legs
 Low blood pressure or poor blood pressure
control
 Muscle weakness or loss of muscle function
(paralysis)
 Numbness
 Sensation changes, including pain and
tingling.
 Tenderness or muscle pain (may be a cramp-
like pain)
 Uncoordinated movement (cannot walk
without help)

6.  Blurred vision and double vision
 Clumsiness and falling
 Difficulty moving face muscles
 Muscle contractions
 Palpitations (sensation of feeling the heart
beat)

7.  Breathing temporarily stops
 Can't take a deep breath
 Difficulty breathing
 Difficulty swallowing
 Drooling
 Fainting

8.  Complete family history
 Physical examination
 Neurological examination
 Cerebrospinal fluid sample
 ECG
 Nerve conduction velocity test
 Pulmonary function tests
 Electromyography (EMG) tests the electrical
activity in muscles

9.  Electromyography (EMG) is a technique for
evaluating and recording the electrical
activity produced by skeletal muscles. EMG is
performed using an instrument called an
electromyograph, to produce a record called
an electromyogram. An electromyograph
detects the electrical potential generated by
muscle cells when these cells are electrically
or neurologically activated.

10.  There is no cure for Guillain-Barre syndrome.
However, many treatments are available to
help reduce symptoms, treat
complications, and speed up recovery
 Antibiotics
 Analgestics
 Plasmapheresis
 High-dose immunoglobulin therapy

11.  Plasmapheresis Plasmapheresis is a blood
purification procedure used to treat
several autoimmune diseases. It is also
known as therapeutic plasma exchange
 High-dose immunoglobulin therapy a blood
product administered intravenously. It
contains the pooled, IgG (immunoglobulin
(antibody) extracted from the plasma of over
one thousand blood donors.

12.  Breathing difficulty (respiratory failure)
 Deep vein thrombosis (blood clots that form
when someone is inactive or confined to bed)
 Increased risk of infections
 Low or unstable blood pressure
 Paralysis
 Pneumonia
 Skin damage (ulcers)
 Sucking food or fluids into the lungs
(aspiration)