The thalamus is located in the middle of the brain between the cerebral cortex and midbrain. It acts as a relay station for all sensory pathways and regulates states of sleep and wakefulness. The thalamus is divided into sensory, motor, limbic, and association nuclei that receive and project different types of sensory and motor information to various parts of the cerebral cortex. Damage to the thalamus can lead to a condition called thalamic syndrome, also known as Dejerine-Roussy syndrome, which involves loss of fine sensation, exaggerated pain sensation, and motor problems due to disturbances in thalamocortical connections.