Foot rot is an anaerobic infection of the soft tissues between the toes in cattle, sheep, and goats that causes lameness. In cattle, it is caused by Fusobacterium necrophorum, while in sheep it is caused by a combination of Bacteroides nodosus and F. necrophorum. The disease is common worldwide and is transmitted between animals through discharges from infected feet. Clinical signs include lameness, fever, and lesions in the interdigital space. Treatment involves systemic and topical antibiotics, cleaning and dressing wounds, and maintaining clean dry living conditions to control spread.
Blue tongue is a non-contagious, infectious, arthropod-borne viral disease of sheep, goat, cattle and deer, with a worldwide distribution. Initially, the disease was reported in sheep in South Africa in 1881 and it was ascribed as “epizootic catarrh”. In 1905, the disease was renamed as “blue tongue”. In India, the first outbreak of blue tongue disease in sheep and goat was reported by Sapre (1964) from Maharashtra. It is listed under category ‘A’ of disease by OIE. The presence of this disease disrupts international commerce by putting a trade barrier on the movement of animals, their germplasm as well as animal products (OIE Bulletin, 1998).
Blue tongue is a non-contagious, infectious, arthropod-borne viral disease of sheep, goat, cattle and deer, with a worldwide distribution. Initially, the disease was reported in sheep in South Africa in 1881 and it was ascribed as “epizootic catarrh”. In 1905, the disease was renamed as “blue tongue”. In India, the first outbreak of blue tongue disease in sheep and goat was reported by Sapre (1964) from Maharashtra. It is listed under category ‘A’ of disease by OIE. The presence of this disease disrupts international commerce by putting a trade barrier on the movement of animals, their germplasm as well as animal products (OIE Bulletin, 1998).
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Fowlpox is contagious viral disease.
Bird of all age is affected by this disease.
Chicken and turkeys are mainly affected by this disease.
Some viral type may also affect pigeon, geese, pheasants and quills.
1-2% mortality rate.
Incubation period 2-3 weeks.
Fowlpox is seen worldwide.
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Fowlpox is contagious viral disease.
Bird of all age is affected by this disease.
Chicken and turkeys are mainly affected by this disease.
Some viral type may also affect pigeon, geese, pheasants and quills.
1-2% mortality rate.
Incubation period 2-3 weeks.
Fowlpox is seen worldwide.
Clinical immunology is the study of diseases caused by disorders of the immune system (failure, aberrant action, and malignant growth of the cellular elements of the system). It also involves diseases of other systems, where immune reactions play a part in the pathology and clinical features.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
2. Foot rot
Definition
An anaerobic infection of the soft tissues of the
interdigital space causing lameness in cattle
,sheep and goat.
3. Foot rot
In cattle:
Synonym: Bovine Interdigital Necrobacillosis
Etiology: Fusobacterium necrophorum
Gram-negative bacteria is a non-spore forming obligate anaerobe
and a normal inhabitant of the alimentary tract (particularly the
rumen), the respiratory tract, and the genital tract.
In sheep:
Synonym: Ovine interdigital dermatitis' and is also called 'foot
scald'.
Etiology: bacteriodes nodosus in combination with
Fusobacterium necrophorum
5. Epidemiology:
●The disease is common in all ages. The disease
has a worldwide distribution
●usually the disease is sporadic and accounts for 5-
15% of cases of lameness in dairy cattle.
● Transmission by discharges from the feet of
infected animals
6. Environmental risk factors
In many but not all regions, the incidence is much higher
during wet, humid weather or when conditions are wet
underfoot.
Stony ground, lanes filled with sharp gravel and pasturing
on coarse stubble also predispose to the condition.
Host risk factors
Cattle of all ages, including young calves ,may be affected
but the disease is much more common in adults.
The highest incidence occurs in cows in the first month of
lactation
7.
8. Economic impacts:
In beef cattle at range the incidence is usually low but many
cases may occur in pure-bred herds and in
feedlot cattle.
Lame cows will lie down for longer and eat less, have
difficulty rising and are at greater risk for teat trampling and
mastitis.
Loss of production occurs and an occasional animal may
suffer a serious involvement of the joint and other deep
structures of the foot necessitating amputation of a digit.
The disease is not fatal but some cases may have to be
slaughtered because of joint involvement.
9. Clinical signs:
lameness appears suddenly, usually in one limb only and
may be accompanied with a fever(39-40℃).
There is temporary depression of milk yield in cows and
affected bulls may show temporary infertility.
The typical lesion occurs in the skin at the top of the
interdigital cleft and takes the form of a fissure which is
moist, red, swollen, and has a characteristic foul odor.
Deeper tissues, such as bone, tendons, and joints, can also be
affected in severe and advanced cases.
10.
11. Pathogenesis:
injury or constant wetting of the skin of the cleft
allow to the organism invade the tissues leading to
acute swelling and necrosis of the skin and SC
tissues may spread to adjacent tendon sheaths,
joint capsules and bone if treatment is delayed or
ineffective.
12.
13. Necropsy Findings
Necropsy examinations are rarely carried out in cases of
foot rot.
Clinical Pathology
Bacteriological examination is not usually necessary for
diagnosis but direct smears of the lesion will usually reveal
large numbers of a mixture of Fusobacterium and
Bacteroides spp.
Diagnosis
The diagnosis is based on history and clinical findings of a
moist, red fissure in the Interdigital space.
15. D.D in sheep:
☞ Foot abscess (It usually affects only one foot, is not contagious and is
characterized by extensive suppuration. The abscess occurs in a single claw on
the foot and there is obvious local heat and pain on palpation).
☞ contagious ecthyma (proliferative lesion with scabs around mouth and
coronet skin)
☞Bluetongue ( coronitis severe erosions around mouth and nasal cavities,
high fever)
☞Foot and mouth disease (vesicles at coronary band and interdigital cleft
and mouth, as outbreak infect all age).
☞Ulcerative dermatitis (spread by physical contact with20% at mating,as
granulating ulcer around mouth, genitalia, on coronet and digits).
☞Strawberry foot rot
☞Laminitis
16. Treatment
Immediate treatment as soon as possible after the onset of
swelling and lameness will give excellent recovery in 2-4
day. (systemic and locally).
procaine penicillin G, 22 000 IU/kg BW.IM twice daily, or
once daily for three consecutive days are effective .
Sodium sulfadimidine (150-200 mg/kg BW) solution given
by IV injection is highly effective.
17. antibiotic treatment for sheep can use any one of
the following :
● Single IM dose of 70 000 U/kg procaine penicillin and
70 mg/kg dihydrostreptomycin.
● Single IM dose of 10 mg/kg. Erythromycin.
● Single IM dose of 20 mg/kg Long-acting oxytetracycline.
18. local treatment by applying a local anesthetic
(xylazine)then the foot is scrubbed, all necrotic tissue
curetted away and apply Any suitable antibacterial spray.
19. it is recommended that the animal be kept standing on
clean dry ground for a few hours after treatment
Ointment preparation may be applied and secured with a
bandage, which may be left on for several days.
20. control:
Foot bathing with copper sulfate 5% in a doorway so that cattle
have to walk through it twice daily . Employ pasture
modifications if possible (e.g., rotate pastures more often, fill
mud holes, remove sharp objects). sheep that are affected with
severe lesion are treated with parenterally administered
antibiotics or culled.