This presentation will help the students of Pharmacy in subjects like Pharmaceutics and industrial pharmacy. Hope you will find it better and helpful.
Regards
Amjad Anwar
email: amjadanwar77@gmail.com
Department of Pharmacy, University Of Malakand
This presentation will help the students of Pharmacy in subjects like Pharmaceutics and industrial pharmacy. Hope you will find it better and helpful.
Regards
Amjad Anwar
email: amjadanwar77@gmail.com
Department of Pharmacy, University Of Malakand
objectives, applications, mechanism of size separation, the official standard of powders, sieves, sieve shaker, cyclone separator, air separator, bag filter, elutriation tank
This was my pharmaceutics presentation for mixing. Provides definitions, mechanism, types of mixers etc.
P.S: I am not the sole presenter. Ideas are from my two other colleagues as well.
Mixer Machines Mixer Machines are used in a number of different applications and industries in order to produce a final product that is the result of mixing or combining two or more materials.
Objectives, applications, Mechanism, official standards of powders, Sieve, Standard for Sieve, Principles, construction, working, uses, merits and demerits of Air separator.
objectives, applications, mechanism of size separation, the official standard of powders, sieves, sieve shaker, cyclone separator, air separator, bag filter, elutriation tank
This was my pharmaceutics presentation for mixing. Provides definitions, mechanism, types of mixers etc.
P.S: I am not the sole presenter. Ideas are from my two other colleagues as well.
Mixer Machines Mixer Machines are used in a number of different applications and industries in order to produce a final product that is the result of mixing or combining two or more materials.
Objectives, applications, Mechanism, official standards of powders, Sieve, Standard for Sieve, Principles, construction, working, uses, merits and demerits of Air separator.
Filtration may be defined as a process of separation of solids from a fluid by passing the same through a porous medium that retains the solids but allows the fluid to pass through. OR
It is a process used to separate solid particles from a liquid with the help of a filter or pores of filter paper. . OR
In simple words, filteration is the action or process of filtering something.
Examples The most common example is making tea.
While preparing tea, a filter or a sieve is used to separate tea leaves from the water.
Through the sieve pores, only water will pass.
The liquid which has obtained after filtration is called the filtrate; in this case, water is the filtrate.
The filter can be a paper, cloth, cotton-wool, asbestos, or glass-wool, sand, or any other porous material.
Filtration may be defined as a process of separation of solids from a fluid by passing the same through a porous medium that retains the solids but allows the fluid to pass through. OR • It is a process used to separate solid particles from a liquid with the help of a filter or pores of filter paper. . OR • In simple words, filteration is the action or process of filtering something. • Examples The most common example is making tea.
Objectives, applications & Theories in FILTRATIONAkankshaPatel55
Filtration is a physical separation process that separates solid matter and fluid from a mixture using a filter medium that has a complex structure through which only the fluid can pass. Solid particles that cannot pass through the filter medium are described as oversize and the fluid that passes through is called the filtrate. Oversize particles may form a filter cake on top of the filter and may also block the filter lattice, preventing the fluid phase from crossing the filter, known as blinding. The size of the largest particles that can successfully pass through a filter is called the effective pore size of that filter.
Filtration is used in many different applications, including:
Water treatment: to remove impurities from water, such as sediment, bacteria, and viruses.
Air filtration: to remove dust, pollen, and other allergens from air.
Oil filtration: to remove impurities from oil, such as dirt, metal shavings, and water.
Chemical processing: to separate solids from liquids in chemical reactions.
Food and beverage processing: to clarify liquids, such as juice, wine, and beer.
There are many different types of filters, each with its own advantages and disadvantages. Some common types of filters include:
Depth filters: These filters are made of a thick layer of material, such as paper, cloth, or sand. The solid particles are trapped in the pores of the filter medium.
Surface filters: These filters are made of a thin layer of material, such as a membrane. The solid particles are trapped on the surface of the filter medium.
Cartridge filters: These filters are self-contained units that can be easily replaced.
Bag filters: These filters are made of a bag of fabric that is suspended in a housing. The solid particles are trapped in the fabric of the bag.
Filtration is commonly the mechanical or physical operation which is used for the separation of products like solids from fluids by interposing a medium through which only the fluid can pass.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
1. Filtration & Clarification
• Filtration is defined as the process in which particles are
separated from a liquid through a permeable medium. The
porous filter medium allows liquid to pass but separates
solid particles.
• Slurry or Feed- The mixture of solid & liquid to be
filtered is known as slurry.
• Filter medium- The porous membrane used for filtration.
• Filter cake- The accumulation of solid on the filter is
known as filter cake.
• Filtrate- The clear liquid passing through the filter is
known as filtrate.
2. Clarification is the term used when the solid present
in the liquid does not exceed 1 % & the filtrate is the
required product.
Mechanism of filtration:
The flow of solid particle is restricted by the filter
medium & the liquid is allowed to pass.
During filtration solid particles on filter media gets
accumulated & acts as a secondary filter medium.
3. Pharmaceutical Application of Filtration
Filtration is done to get clear solutions during
preparation of syrups, oral liquids, drops, etc.
It removes solid particles present in the liquids &
avoids contamination.
It is also used to sterilize liquid products.
It is used to prepare homogenous mixture of liquids.
4. Theory of filtration
The rate of filtration is directly proportional to
permeability constant for filter medium & filter cake
(K), area of filter bed (A) & the pressure difference
across the filter medium & filter cake (∆P) & inversely
proportional to thickness of the filter cake (l) &
viscosity of the fluid (η). It is called as Darcy’s law.
dv = KA∆P
dt ηl
5. Factors affecting the rate of filtration
The factors affecting the rate of filtration of any liquid
is expressed by Darcy’s Law which is given as:
dv = KA∆P
dt ηl
1) Area of the Filter Surface
Rate of Filtration is directly proportional to the Filter
surface area dv ∞ A
dt
6. 2) Particle size of the solids
Rate of Filtration is directly proportional to the
particle size of the solids to be removed.
dv ∞ Particle size
dt
3) Pore size of the Filter Media
Rate of Filtration is directly proportional to the pore
size of the filter media.
dv ∞ Pore size
dt
7. 4) The resistance of the filter cake & filter media
Rate of Filtration is inversely proportional to the
resistance of filter cake & filter media.
dv ∞ 1
dt resistance of filter cake & filter media
5) Viscosity of the liquid to be filtered
Rate of Filtration is inversely proportional to the
viscosity of the liquid to be filtered.
dv ∞ 1
dt η
8. 6) Temperature
When temperature increases viscosity decreases and
hence rate of filtration increases.
7) Pressure Difference across the filter
Rate of Filtration is directly proportional to the
pressure difference across the filter.
dv ∞ ∆P
dt
9. Filter Media
The surface or medium upon which solids are retained
in the process of filtration is known as filter media.
An ideal filter media should have following properties:
1. It should be chemically inert (non-reactive).
2. It should have high retention power for the solids but
should allow maximum passage of liquids.
3. It should have sufficient mechanical strength to
withstand filtration pressure.
4. It should absorb negligible amount of dissolved
material.
5. It should be resistant to the corrosive action of the
liquid.
10. While selecting the filter media, the following factors
must be taken into consideration:
1. The size of the particles to be filtered.
2.The amount of the liquid to be filtered.
3. Nature of the product to be filtered. e.g: solution,
suspension or viscous preparation
4.Purpose of the filtration. e.g: clarification, sterilization
Some Filter media used in filtration are:
1. Filter Paper 5. Cotton wool
2. Sintered Glass 6. Glass wool
3. Membrane Filters 7. Asbestos
4. Cartridge Filters 8. Woven materials
11. Filter Aid
The substances which are added to the liquid to be
filtered that reduces the resistance of filter cake &
increases filtration are known as filter aid. These
substances form porous, non-compressible cake
which can retain solid particles but allows liquid to
flow through it. Usually 0.1-0.5% filter aid can be
added to the liquid to be filtered.
12. An ideal filter aid should have following characters:
1. It should be chemically inert.
2.It should have low specific gravity.
3. It should be insoluble in the liquid to be filtered.
4.It should form a porous cake.
5.It should be readily recoverable from the liquid.
Some filter aid used in the filtration are:
1. Hyflo
2.Talc
3. Charcoal
4.Magnesium Carbonate
5.Bentonite
16. Sintered glass filters consists of sintered glass particles
with very small porosities fitted in pyrex funnel.
(Sinter- To fuse together by heating without melting)
The porosity of sintered glass filter depends upon the
size of glass particles used.
They are used for the filtration of parenteral products,
opthalmic preparations, etc.
For bacterial filtration grade 5 sintered glass is used
which can filter upto 2µm.
Sintered glass filters are very fragile, so they must be
handled carefully.
18. Filter candles are cylindrical tube made up of
porcelain or kieselguhr containing filter elements
with different porosity grades. It is connected to
vacuum pump for reducing pressure during filtration.
Filter candles consists of 3 major components:
The vessel
The filtering elements
The cake discharge medium
The liquid to be filtered is passed through the bottom
inlet which allows fast settling of solid & cake
formation.
It is used for the sterilization of the solutions.
20. Filter press consists of number of frames & plates
arranged alternatively used for industrial filtration.
Each set of frame & plate works as a unit. Frames are
open with inlet for liquid to be filtered. Plates have
grooved surface to support filter cloth & contains
outlet for filtrate.
The liquid to be filtered is passed through filter press
under pressure. The liquid passes through filter
medium on the plate & filter cake is retained in the
frame. Finally, filtrate is collected through the outlet.
21.
22. Advantages of filter press:
1. It is simple in construction.
2.It provides large area for filtration.
3. It is easy for cleaning & maintainance.
4.Filter cloth can be easily replaced.
5.Filter media can be selected according to porosity grade.
Disadvantages of filter press:
1. It is used for batch filtration, so small scale filtration is
not economical.
2.Operation cost is high.
3. It is suitable for slurries containing less than 5 % solids.