This document summarizes factors that affect the dentogingival junction. Bacteria can initiate tissue destruction by increasing permeability in the junctional epithelium and inducing apoptosis of invaded cells, leading to coronal degeneration and detachment of the junctional epithelium. Trauma from periodontal surgeries or accidental sources like probing or tooth preparations can widen the marginal periodontal ligament space and narrow the interproximal alveolar bone. The formation of periodontal pockets results in apical migration of the junctional epithelium and symptoms like gingival bleeding and tooth mobility. While gingivitis can stimulate initial increases in leukocytes and intracellular debris in the junctional epithelium and connective tissue, the established lesion