This document discusses the different types of root resorption, including external root resorption. External root resorption is classified into external surface resorption, external inflammatory resorption, external replacement resorption, and external cervical resorption. External surface resorption is a self-limiting resorption caused by trauma or orthodontic treatment. External inflammatory resorption is often seen radiographically as an extensive lesion caused by necrotic pulp. External replacement resorption replaces the root surface with bone in a process called ankylosis. External cervical resorption is a localized resorptive lesion of the cervical area that may progress in an apical or coronal direction.
Fixed partial dentures transmit forces through the abutments to the periodontium. Failures are due to poor engineering, the use of improper materials, inadequate tooth preparation, and faulty fabrication. Of particular concern to prosthodontist is the selection of teeth for abutments. They must recognize the forces developed by the oral mechanism, and resistance.
Successful selection of abutments for fixed partial dentures requires sensitive diagnostic ability. Thorough knowledge of anatomy, ceramics, the chemistry and physics of dental materials, metallurgy, Periodontics, phonetics, physiology, radiology and the mechanics of oral function is fundamental.
Fixed partial dentures transmit forces through the abutments to the periodontium. Failures are due to poor engineering, the use of improper materials, inadequate tooth preparation, and faulty fabrication. Of particular concern to prosthodontist is the selection of teeth for abutments. They must recognize the forces developed by the oral mechanism, and resistance.
Successful selection of abutments for fixed partial dentures requires sensitive diagnostic ability. Thorough knowledge of anatomy, ceramics, the chemistry and physics of dental materials, metallurgy, Periodontics, phonetics, physiology, radiology and the mechanics of oral function is fundamental.
A concise and brief presentation on cleaning and shaping of root canals. Colorful and well pictured. Ideal for UG students and PG students to get a good understanding of BMP techniques.
a detailed account of the principles of tooth preparation with main reference from Shillingburg
The presentation is available on request. Mail me at apurvathampi@gmail.com
This presentation specifically deals with the maxillary and mandibular Major connectors used in a cast partial denture. it also mentions the uses, advantages and disadvantages of each,
A concise and brief presentation on cleaning and shaping of root canals. Colorful and well pictured. Ideal for UG students and PG students to get a good understanding of BMP techniques.
a detailed account of the principles of tooth preparation with main reference from Shillingburg
The presentation is available on request. Mail me at apurvathampi@gmail.com
This presentation specifically deals with the maxillary and mandibular Major connectors used in a cast partial denture. it also mentions the uses, advantages and disadvantages of each,
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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About failures of root canal treatment and retreatment. This presentation describes about various techniques for gutta percha removal, posts removal, pastes removal, and removal of separated instrument
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
4. EXTERNAL ROOT RESORPTION
• Definition
External resorption is the progressive loss of tooth structure (Dentin and
cementum) from the external surface of the tooth by the action of
osteoclasts.
• Classification:
• External Surface Resorption
• External Inflammatory Resorption
• External Replacement Resorption
• External Cervical Resorption
5. 1. EXTERNAL SURFACE RESORPTION
• Is a self-limiting resorption that is transient.
• Small, superficial resorption cavities in the cementum and the outermost
layers of the dentin without an inflammatory reaction in the PDL.
• Caused by: traumatic injuries or orthodontic treatment..
• When trauma/pressure discontinued – spontaneous healing occur – -
typical feature of REPAIR RELATED RESORPTION
• This process is thought to be exceedingly common but grossly under-
reported as it is sub-clinical.
6. TREATMENT
• Endodontic Implication:
• Primarily periodontal injury – endodontic intervention not indicated.
• If trauma/pressure eliminated – almost 100% repair
• If root apex resorbed - excessive mobility becomes a problem, if root is shorter than
mm
7. 2. EXTERNAL INFLAMMATORY
RESORPTION
• Is often seen radiographically as an extensive peri-radicular
radiolucency associated with an extensive inflammatory response to
endodontic pathosis.
• Causes: Necrotic pulp.
• Bacteria primarily located in pulp & dentinal tubules trigger
osteoclastic activity resulting in both tooth and bone resorption..
• Resorption can affect all parts of root.
• Diagnosed 2-4 weeks after injury.
• Resorption rapidly progress – total root resorption within few months.
• Most common after avulsion and luxation injuries
8. Clinical Findings:
• Increased mobility
• Dull percussion tone (Tender to percussion and palpation)
• Sometimes tooth extruded
• Negative EPT and thermal testing
• Sometimes sinus tract develop
Radiographic Findings:
• Radiolucency on the external root surface and adjacent bone.
• Extensive root resorption if lesion is long standing in origin
9. TREATMENT
• Endodontic Implication:
• Non-surgical root canal treatment is indicated - to remove
osteoclast promoting factors (bacterial toxins)
Treatment:
• Use of Calcium Hydroxide intracanal medicament is recommended
to remove bacterial stimulation from both the root canal and
dentinal tubules.
10. 3. EXTERNAL REPLACEMENT (ANKYLOTIC)
RESORPTION
• This is the process of replacement of root surface with bone otherwise known as
ankylosis.
Causes
Severe traumatic injuries (intrusive luxation or avulsion)
Clinical Findings Appear firm in socket
High pitched metallic sound on percussion
Infra-occlusion may be present
Radiographic Findings
Resorption lacunae are filled with bone
Periodontal ligament space is missing
11. TREATMENT
• Endodontic implications:
• Endodontic therapy- cannot arrest progressive ankylosis related resorption
• In vital pulp - no endodontic procedure
• In pulp necrosis - root canal treatment
• Prevention by minimizing periodontal ligament damage immediately following an
injury is the only treatment.
• Decoronation and submergence maybe an option in the developing dentition to
for growth to cease before considering dental implant replacement
12. 4. EXTERNAL CERVICAL RESORPTION
• External cervical resorption is a localized
resorptive lesion of the cervical area of the root
below the epithelial attachment (thus it may not
always be in the cervical region.)
• In a vital tooth unless the lesion is extensive there
is rarely pulpal involvement.
• Potential predisposing factors: dental trauma,
orthodontic treatment, intracoronal bleaching,
periodontal therapy and idiopathic origin.
• Heithersay et al – studied 259 teeth with invasive
cervical resorption –
23% : related to orthodontic treatment
15% : acute trauma
14% : cervical restoration
13. • Pathogenesis: • Initial cervical resorption cavity gradually spreads • Progress in apical &
coronal direction – leading to root fracture
Expanding lesion- show as
a “pink spot” next to
cervical margin
Clinical
Findings Cervical bowl-shaped
lesion is the start of
invasive progression of
resorption in coronal &
apical direction.
Pulp canal not invaded in
initial phase
Radiographic
Findings
14.
15. TREATMENT
• Endodontic Implications:
• Pathology entirely related to PDL defect
• Does not need endodontic treatment primarily
• When invasive nature finally encroaches pulp - need endodontic treatment
• Treatment:
• • Essentially, treatment involves complete removal of the resorptive tissue and
restoring the resulting defect with a plastic tooth-coloured restoration.
16. REFERENCES
• https://pocketdentistry.com/root-resorption-2/
• Darcey, James & Qualtrough, Alison. (2013). Resorption: Part 1. Pathology,
classification and aetiology. British dental journal. 214. 439-51. 10.1038/sj.bdj.2013.431.
• Z. F., I. T., & S. L. (2003). Root resorption - Diagnosis, classification and treatment
choices based on stimulation factors. Dental Traumatology, 19, 175-182.