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Done by: Iten Abdalfattah ,Rana Alaa ,Mayar Said ,Abeer
Ahmed
Semester Four
Under Supervision of : A.Prof. Samah Kamel
 It is the interface and
zone of attachment
between the gingiva
and enamel or
cementum of the tooth.
It holds in place the
junctional or
attachment epithelium.
 Diabetes mellitus.
 Smoking.
 Orthodontic treatment.
 Chronic inflammatory periodontal disease.
 Type I and type II of primary diabetes mellitus leads to
periodontal disease, due to uncontrolled blood glucose
level.
 The chronic hyperglycemia leads to:
 Production of AGEs which binds to macrophage,
making it hyper-reactive and produce pro-
inflammatory cytokines.
 AGEs binds to endothelial cells, making it hyper
permeable and hyper expressive for adhesion to
molecules.
 AGEs makes the
fibroblast produce less
collagen, which leads to:
 Hyper-inflammatory
responses.
 Vascular modification.
 Altered healing of
wounds.
 Occurrence of
periodontitis and
gingivitis.
 Nicotine found in cigarette
activates the release of
epinephrine, this
substance promote VC of
gingival blood vessels,
which cause a reduction in
the blood flow leading to:
 Loss of vitality of gingival
epithelium.
 Helps in onset of gingival
ulceration (ANUG).
Usually, it does not cause any damage to the gingival tissues, but in some
patients it may cause some changes which subsequently leads to gingival
retraction on the labial surface of incisors and canines and on the buccal
surface of posterior teeth.
Orthodontic treatment
 Loss of supporting bone by
inflammatory process.
 Loss of tissue by enzymatic
digestion.
 These two leads to apical
migration of the gingiva
and exposure of the root,
this is known as gingival
recession.
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228
943/ (2011)
 http://www.ccij-online.org/article.asp?issn=2278-
0513;year=2016;volume=5;issue=2;spage=99;epage=102;
aulast=Shah (2016)
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944
726/ (2016)
Factors affecting dentogingival junction

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Factors affecting dentogingival junction

  • 1. Done by: Iten Abdalfattah ,Rana Alaa ,Mayar Said ,Abeer Ahmed Semester Four Under Supervision of : A.Prof. Samah Kamel
  • 2.  It is the interface and zone of attachment between the gingiva and enamel or cementum of the tooth. It holds in place the junctional or attachment epithelium.
  • 3.  Diabetes mellitus.  Smoking.  Orthodontic treatment.  Chronic inflammatory periodontal disease.
  • 4.  Type I and type II of primary diabetes mellitus leads to periodontal disease, due to uncontrolled blood glucose level.  The chronic hyperglycemia leads to:  Production of AGEs which binds to macrophage, making it hyper-reactive and produce pro- inflammatory cytokines.  AGEs binds to endothelial cells, making it hyper permeable and hyper expressive for adhesion to molecules.
  • 5.  AGEs makes the fibroblast produce less collagen, which leads to:  Hyper-inflammatory responses.  Vascular modification.  Altered healing of wounds.  Occurrence of periodontitis and gingivitis.
  • 6.  Nicotine found in cigarette activates the release of epinephrine, this substance promote VC of gingival blood vessels, which cause a reduction in the blood flow leading to:  Loss of vitality of gingival epithelium.  Helps in onset of gingival ulceration (ANUG).
  • 7. Usually, it does not cause any damage to the gingival tissues, but in some patients it may cause some changes which subsequently leads to gingival retraction on the labial surface of incisors and canines and on the buccal surface of posterior teeth. Orthodontic treatment
  • 8.  Loss of supporting bone by inflammatory process.  Loss of tissue by enzymatic digestion.  These two leads to apical migration of the gingiva and exposure of the root, this is known as gingival recession.
  • 9.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228 943/ (2011)  http://www.ccij-online.org/article.asp?issn=2278- 0513;year=2016;volume=5;issue=2;spage=99;epage=102; aulast=Shah (2016)  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944 726/ (2016)