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Research Ethics, Research
Integrity and chemical Laboratory
safety
Vijay P Jadhav
Research Scholar
Dept. of Dairy Chemistry
Ethics
 Ethics are standards of moral conduct
 Standards of right and wrong behavior
 A gauge of personal integrity
 The basis of trust and cooperation in
relationships with others
Research Ethics
 Rules for distinguishing between right and
wrong.
 Avoids Confucius during research.
 Most people learn ethical norms at home, at
school, in church, or in other social settings.
 Moral development occurs throughout life.
 Promote the aims of research, such as
knowledge, truth, and avoidance of error.
Ethical Principals
 Ethical principals are tools which are used
to think in difficult situations.
 Three useful ethical principals:
 Minimizing harm
 Respecting autonomy
 Protecting privacy
 Treating people equitably
 Offering reciprocity
Need to follow Ethical
principle
 Promote the aims of research.
 Prohibitions against falsifying, or
misrepresenting research data
promote the truth and avoid error.
 Ethical standards promote
the values that are essential to
collaborative work, such as trust,
accountability, mutual respect, and
fairness.
Research Integrity 
 May be defined as “active adherence to the
ethical principles and professional standards
essential for the responsible practice of
research”.
 NAS report definition: "For individuals
research integrity is an aspect of moral
character and experience”.
It includes following practices
 HONESTY
convey information truthfully and honoring commitments
 ACCURACY
report findings precisely and take care to avoid errors
 EFFICIENCY
use resources wisely and avoid waste
 OBJECTIVITY
let the facts speak for themselves and avoid improper
bias
 Collegiality in scientific interactions, communications and
sharing of resources.
 Disclosure of conflicts of interest.
 Humanity
care of animals in the conduct of research.
 Mutual Responsibilities
Adherence to the mutual responsibilities of mentors and
trainees.
Important Terms
INTELLECTUAL PROPERTY:
Intangible creations protected by law
TRADE SECRET:
Intellectual work or products belonging to a business,
not in public domain
COPYRIGHT:
Statutory grant protecting intellectual property from
copying by others for 28 years
PATENT:
Legal document granting owner exclusive monopoly
on an invention for 17 years
Chemical Laboratory Safety
What are the additional hazards from
chemical materials?
 Toxic substances
 Solvents
 Corrosives
 Flammables
 Irritants
 Carcinogens
 Teratogens
 Mutagens
 Explosives
 Radiation
and many, many more
How do toxic materials enter the body?
 By mouth (contaminated
fingers!)
 By breathing in gases,
aerosols or powder
 By skin contact or damage
 By absorption through
intact skin
 By splashes into the eyes
What legislation applies?
 Control of Substances Hazardous to HealthControl of Substances Hazardous to Health
Use data sheets and other relevant information to
assess risk
 Consider not only reactants but also
intermediates, products and waste
 Take into account the format (e.g. solution or
powder) and the quantity to be used
 Determine safe working procedures
 Determine emergency procedures, ensuring that
all equipment and “mop-up” materials are
available
 Consider correct waste disposal
Fume Cupboards
 Ensure that the equipment
is working properly
 Ensure you know the
meaning of warning signals
and how to use any
controls
 Close the sash unless
loading or unloading
 Do not use fume
cupboards for storage
 Keep the work area clear
of other materials etc
Materials
 Obtain the minimumminimum amounts needed
for your work
 Ensure that all containers are clearly
labelledlabelled with their contents and a
hazard label
 Toxic materials must be locked awaylocked away
 Corrosive substances must be stored
securely at a low level in banded traysbanded trays
 Keep flammable materials in speciallyspecially
designed cupboardsdesigned cupboards and only have out
the minimum for immediate use (<50L
per room)
 Store acids, bases & solvents
separately
Good practice
 Never mouth-pipette
 Always dilute
concentrated acids by
adding the acid to water,
never the reverse
 Never carry Winchesters
by the neck – always
use a carrier
 Always leave benches,
balances etc. clean &
tidy after use
Radio-Active Materials & Work with
Lasers
 Work with radio-active
materials and lasers
requires special training
 You must notmust not use them
without authorisation
and training
 Your Departmental
Safety Staff can advise
or contact Trevor
Moseley in Safety
Services
Work with Cyanides & Hydrofluoric
Acid
 If you plan to use Cyanides or
Hydrofluoric Acid, you will have
to have specific permission from
your Departmental Safety Officer
 Attendance at a training course
at Safety Services will normally
be required
 The dangers of both substances,
especially hydrofluoric acid can
be greatly underestimated with
potentially fatalfatal results.
 They are both VERYVERY
DANGEROUSDANGEROUS substances
When in doubt – ASK!!!
 Do not carry out a
new or unfamiliar
procedure until you
have been fully
trained & understand
the precautions
necessary for safe
working
 DO NOT GUESS!!!!DO NOT GUESS!!!!
Bibliography
 J. P. Swazey, K. S. Louis, and M. S. Anderson, “The ethical training of
graduate students requires serious and continuing attention,” Chronicle of
Higher Education 9 (March 1994):B1–2;
 J. P. Swazey, “Ethical problems in academic research,” American Scientist
81(Nov./Dec. 1993):542–53.
 Ethical Guidelines to Publication of Chemical Research (ACS Pubs.Div.)
http://pubs.acs.org/userimages/ContentEditor/1218054468605/ethics.pdf
 National lAcademy Press, Wash. D.C, 2009
http://www.nap.edu/catalog/12192.html
 IEEE Policy Statement on Self-Plagiarism
http://www.comsoc.org/pubs/jrnal/transcom/Self_Plagiarism.pdf
 Managing Allegations of Scientific Misconduct: A Guidance Document for
Editors, January 2000, Office of Research Integrity, Office of Public Health
and Science, U.S. Dept. of Health and Human Services
http://ori.dhhs.gov.
Cont..
 National Institutes of Health Office of Extramural Research website.
http://grants.nih.gov/grants/policy/datasharing/data_sharing_faqs.htm.
 The Office of Scientific and Technology Policy website.
http://www.ostp.gov/html/001207_3.html.
 United States Department of Agriculture website.
http://www.aphis.usda.gov/oa/pubs/awact.html

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Research Ethics, Research Integrity and chemical Laboratory safety

  • 2. Research Ethics, Research Integrity and chemical Laboratory safety Vijay P Jadhav Research Scholar Dept. of Dairy Chemistry
  • 3. Ethics  Ethics are standards of moral conduct  Standards of right and wrong behavior  A gauge of personal integrity  The basis of trust and cooperation in relationships with others
  • 4. Research Ethics  Rules for distinguishing between right and wrong.  Avoids Confucius during research.  Most people learn ethical norms at home, at school, in church, or in other social settings.  Moral development occurs throughout life.  Promote the aims of research, such as knowledge, truth, and avoidance of error.
  • 5. Ethical Principals  Ethical principals are tools which are used to think in difficult situations.  Three useful ethical principals:  Minimizing harm  Respecting autonomy  Protecting privacy  Treating people equitably  Offering reciprocity
  • 6. Need to follow Ethical principle  Promote the aims of research.  Prohibitions against falsifying, or misrepresenting research data promote the truth and avoid error.  Ethical standards promote the values that are essential to collaborative work, such as trust, accountability, mutual respect, and fairness.
  • 7. Research Integrity   May be defined as “active adherence to the ethical principles and professional standards essential for the responsible practice of research”.  NAS report definition: "For individuals research integrity is an aspect of moral character and experience”.
  • 8. It includes following practices  HONESTY convey information truthfully and honoring commitments  ACCURACY report findings precisely and take care to avoid errors  EFFICIENCY use resources wisely and avoid waste  OBJECTIVITY let the facts speak for themselves and avoid improper bias
  • 9.  Collegiality in scientific interactions, communications and sharing of resources.  Disclosure of conflicts of interest.  Humanity care of animals in the conduct of research.  Mutual Responsibilities Adherence to the mutual responsibilities of mentors and trainees.
  • 10. Important Terms INTELLECTUAL PROPERTY: Intangible creations protected by law TRADE SECRET: Intellectual work or products belonging to a business, not in public domain COPYRIGHT: Statutory grant protecting intellectual property from copying by others for 28 years PATENT: Legal document granting owner exclusive monopoly on an invention for 17 years
  • 12. What are the additional hazards from chemical materials?  Toxic substances  Solvents  Corrosives  Flammables  Irritants  Carcinogens  Teratogens  Mutagens  Explosives  Radiation and many, many more
  • 13. How do toxic materials enter the body?  By mouth (contaminated fingers!)  By breathing in gases, aerosols or powder  By skin contact or damage  By absorption through intact skin  By splashes into the eyes
  • 14. What legislation applies?  Control of Substances Hazardous to HealthControl of Substances Hazardous to Health Use data sheets and other relevant information to assess risk  Consider not only reactants but also intermediates, products and waste  Take into account the format (e.g. solution or powder) and the quantity to be used  Determine safe working procedures  Determine emergency procedures, ensuring that all equipment and “mop-up” materials are available  Consider correct waste disposal
  • 15. Fume Cupboards  Ensure that the equipment is working properly  Ensure you know the meaning of warning signals and how to use any controls  Close the sash unless loading or unloading  Do not use fume cupboards for storage  Keep the work area clear of other materials etc
  • 16. Materials  Obtain the minimumminimum amounts needed for your work  Ensure that all containers are clearly labelledlabelled with their contents and a hazard label  Toxic materials must be locked awaylocked away  Corrosive substances must be stored securely at a low level in banded traysbanded trays  Keep flammable materials in speciallyspecially designed cupboardsdesigned cupboards and only have out the minimum for immediate use (<50L per room)  Store acids, bases & solvents separately
  • 17. Good practice  Never mouth-pipette  Always dilute concentrated acids by adding the acid to water, never the reverse  Never carry Winchesters by the neck – always use a carrier  Always leave benches, balances etc. clean & tidy after use
  • 18. Radio-Active Materials & Work with Lasers  Work with radio-active materials and lasers requires special training  You must notmust not use them without authorisation and training  Your Departmental Safety Staff can advise or contact Trevor Moseley in Safety Services
  • 19. Work with Cyanides & Hydrofluoric Acid  If you plan to use Cyanides or Hydrofluoric Acid, you will have to have specific permission from your Departmental Safety Officer  Attendance at a training course at Safety Services will normally be required  The dangers of both substances, especially hydrofluoric acid can be greatly underestimated with potentially fatalfatal results.  They are both VERYVERY DANGEROUSDANGEROUS substances
  • 20. When in doubt – ASK!!!  Do not carry out a new or unfamiliar procedure until you have been fully trained & understand the precautions necessary for safe working  DO NOT GUESS!!!!DO NOT GUESS!!!!
  • 21. Bibliography  J. P. Swazey, K. S. Louis, and M. S. Anderson, “The ethical training of graduate students requires serious and continuing attention,” Chronicle of Higher Education 9 (March 1994):B1–2;  J. P. Swazey, “Ethical problems in academic research,” American Scientist 81(Nov./Dec. 1993):542–53.  Ethical Guidelines to Publication of Chemical Research (ACS Pubs.Div.) http://pubs.acs.org/userimages/ContentEditor/1218054468605/ethics.pdf  National lAcademy Press, Wash. D.C, 2009 http://www.nap.edu/catalog/12192.html  IEEE Policy Statement on Self-Plagiarism http://www.comsoc.org/pubs/jrnal/transcom/Self_Plagiarism.pdf  Managing Allegations of Scientific Misconduct: A Guidance Document for Editors, January 2000, Office of Research Integrity, Office of Public Health and Science, U.S. Dept. of Health and Human Services http://ori.dhhs.gov.
  • 22. Cont..  National Institutes of Health Office of Extramural Research website. http://grants.nih.gov/grants/policy/datasharing/data_sharing_faqs.htm.  The Office of Scientific and Technology Policy website. http://www.ostp.gov/html/001207_3.html.  United States Department of Agriculture website. http://www.aphis.usda.gov/oa/pubs/awact.html