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Chemical Laboratory Safety
Additional Information
Where to start
 Before looking at this
presentation, ensure
that you have
watched the one on
General Laboratory
Safety
What are the additional hazards from
chemical materials?
 Toxic substances
 Solvents
 Corrosives
 Flammables
 Irritants
 Carcinogens
 Teratogens
 Mutagens
 Explosives
 Radiation
and many, many more
How do toxic materials enter the body?
 By mouth (contaminated
fingers!)
 By breathing in gases,
aerosols or powder
 By skin contact or damage
 By absorption through
intact skin
 By splashes into the eyes
What legislation applies? (1)
 Control of Substances Hazardous to HealthControl of Substances Hazardous to Health
Regs 2004Regs 2004
 Use data sheets and other relevant information (eg
EH40) to assess risk
 Consider not only reactants but also intermediates,
products and waste
 Take into account the format (eg solution or
powder) and the quantity to be used
 Determine safe working procedures
 Determine emergency procedures, ensuring that all
equipment and “mop-up” materials are available
 Consider correct waste disposal
What legislation applies? (2)
 Other relevantOther relevant
legislation includes:legislation includes:
 Dangerous Substances
& Explosive
Atmosphere Regs 2005
 Pressure Systems
Regs 2000
 Provision & Use of
Work Equipment Regs
1998
This list is not
exhaustive!!
Fume Cupboards
 Ensure that the equipment
is working properly
 Ensure you know the
meaning of warning signals
and how to use any
controls
 Close the sash unless
loading or unloading
 Do not use fume
cupboards for storage
 Keep the work area clear
of other materials etc
Materials
 Obtain the minimumminimum amounts needed
for your work
 Ensure that all containers are clearly
labelledlabelled with their contents and a
hazard label
 Toxic materials must be locked awaylocked away
 Corrosive substances must be stored
securely at a low level in bunded traysbunded trays
 Keep flammable materials in speciallyspecially
designed cupboardsdesigned cupboards and only have out
the minimum for immediate use (<50L
per room)
 Store acids, bases & solvents
separately
Good practice
 Never mouth-pipette
 Always dilute
concentrated acids by
adding the acid to water,
never the reverse
 Never carry Winchesters
by the neck – always
use a carrier
 Always leave benches,
balances etc clean &
tidy after use
Radio-Active Materials & Work with Lasers
 Work with radio-active
materials and lasers
requires special training
 You must notmust not use them
without authorisation
and training
 Your Departmental
Safety Staff can advise
or contact Trevor
Moseley in Safety
Services
Work with Cyanides & Hydrofluoric Acid
 If you plan to use Cyanides or
Hydrofluoric Acid, you will have to
have specific permission from
your Departmental Safety Officer
 Attendance at a training course
at Safety Services will normally
be required
 The dangers of both substances,
especially hydrofluoric acid can
be greatly underestimated with
potentially fatalfatal results.
 They are both VERYVERY
DANGEROUSDANGEROUS substances
When in doubt – ASK!!!
 Do not carry out a
new or unfamiliar
procedure until you
have been fully
trained & understand
the precautions
necessary for safe
working
 DO NOT GUESS!!!!DO NOT GUESS!!!!

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Chemical Laboratory Safety by The University of Sheffield

  • 2. Where to start  Before looking at this presentation, ensure that you have watched the one on General Laboratory Safety
  • 3. What are the additional hazards from chemical materials?  Toxic substances  Solvents  Corrosives  Flammables  Irritants  Carcinogens  Teratogens  Mutagens  Explosives  Radiation and many, many more
  • 4. How do toxic materials enter the body?  By mouth (contaminated fingers!)  By breathing in gases, aerosols or powder  By skin contact or damage  By absorption through intact skin  By splashes into the eyes
  • 5. What legislation applies? (1)  Control of Substances Hazardous to HealthControl of Substances Hazardous to Health Regs 2004Regs 2004  Use data sheets and other relevant information (eg EH40) to assess risk  Consider not only reactants but also intermediates, products and waste  Take into account the format (eg solution or powder) and the quantity to be used  Determine safe working procedures  Determine emergency procedures, ensuring that all equipment and “mop-up” materials are available  Consider correct waste disposal
  • 6. What legislation applies? (2)  Other relevantOther relevant legislation includes:legislation includes:  Dangerous Substances & Explosive Atmosphere Regs 2005  Pressure Systems Regs 2000  Provision & Use of Work Equipment Regs 1998 This list is not exhaustive!!
  • 7. Fume Cupboards  Ensure that the equipment is working properly  Ensure you know the meaning of warning signals and how to use any controls  Close the sash unless loading or unloading  Do not use fume cupboards for storage  Keep the work area clear of other materials etc
  • 8. Materials  Obtain the minimumminimum amounts needed for your work  Ensure that all containers are clearly labelledlabelled with their contents and a hazard label  Toxic materials must be locked awaylocked away  Corrosive substances must be stored securely at a low level in bunded traysbunded trays  Keep flammable materials in speciallyspecially designed cupboardsdesigned cupboards and only have out the minimum for immediate use (<50L per room)  Store acids, bases & solvents separately
  • 9. Good practice  Never mouth-pipette  Always dilute concentrated acids by adding the acid to water, never the reverse  Never carry Winchesters by the neck – always use a carrier  Always leave benches, balances etc clean & tidy after use
  • 10. Radio-Active Materials & Work with Lasers  Work with radio-active materials and lasers requires special training  You must notmust not use them without authorisation and training  Your Departmental Safety Staff can advise or contact Trevor Moseley in Safety Services
  • 11. Work with Cyanides & Hydrofluoric Acid  If you plan to use Cyanides or Hydrofluoric Acid, you will have to have specific permission from your Departmental Safety Officer  Attendance at a training course at Safety Services will normally be required  The dangers of both substances, especially hydrofluoric acid can be greatly underestimated with potentially fatalfatal results.  They are both VERYVERY DANGEROUSDANGEROUS substances
  • 12. When in doubt – ASK!!!  Do not carry out a new or unfamiliar procedure until you have been fully trained & understand the precautions necessary for safe working  DO NOT GUESS!!!!DO NOT GUESS!!!!