The endocrine system consists of glands that secrete hormones directly into the bloodstream to regulate bodily functions. Key glands include the pituitary, thyroid, parathyroid, adrenals, pancreas and gonads. Hormones control processes like metabolism, growth, development, reproduction and mood. The hypothalamus and pituitary gland work together to control hormone release from other glands and maintain homeostasis.
22.chemical control & coordination in one shot.pptxanonymous
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There are special chemicals which act as hormones and provide chemical
coordination, integration and regulation in the human body. These hormones
regulate metabolism, growth and development of our organs, the endocrine glands
or certain cells. The endocrine system is composed of hypothalamus, pituitary
and pineal, thyroid, adrenal, pancreas, parathyroid, thymus and gonads (testis
and ovary). In addition to these, some other organs, e.g., gastrointestinal tract,
kidney, heart etc., also produce hormones. Progesterone plays a major role in the maintenance of pregnancy as
well as in mammary gland development and lactation. The atrial wall of the heart
produces atrial natriuretic factor which decreases the blood pressure. Kidney
produces erythropoietin which stimulates erythropoiesis. The gastrointestinal tract
secretes gastrin, secretin, cholecystokinin and gastric inhibitory peptide. These
hormones regulate the secretion of digestive juices and help in digestion.
22.chemical control & coordination in one shot.pptxanonymous
Â
There are special chemicals which act as hormones and provide chemical
coordination, integration and regulation in the human body. These hormones
regulate metabolism, growth and development of our organs, the endocrine glands
or certain cells. The endocrine system is composed of hypothalamus, pituitary
and pineal, thyroid, adrenal, pancreas, parathyroid, thymus and gonads (testis
and ovary). In addition to these, some other organs, e.g., gastrointestinal tract,
kidney, heart etc., also produce hormones. Progesterone plays a major role in the maintenance of pregnancy as
well as in mammary gland development and lactation. The atrial wall of the heart
produces atrial natriuretic factor which decreases the blood pressure. Kidney
produces erythropoietin which stimulates erythropoiesis. The gastrointestinal tract
secretes gastrin, secretin, cholecystokinin and gastric inhibitory peptide. These
hormones regulate the secretion of digestive juices and help in digestion.
Classification of hormones, mechanism of hormone action, structure
and functions of pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pancreas, pineal gland, thymus and their disorders.
Classification of hormones, mechanism of hormone action, structure
and functions of pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pancreas, pineal gland, thymus and their disorders.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
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Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
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Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? â The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
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June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMENâS HEALTH: FERTILITY PRESERVATION
- WHATâS NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Tom Selleck Health: A Comprehensive Look at the Iconic Actorâs Wellness Journeygreendigital
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Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Â
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Â
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
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i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
Itâs work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2â3 criteria; moderate AUD: 4â5 criteria; severe AUD: 6â11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
2. Introduction
⢠Endocrine system a control system of ductless glands that secrete hormones.
⢠There are 2 types of hormones:
⢠Steroidal &
⢠Non-steroidal
⢠The multiple hormone systems play a key role in regulating almost all body
functions, including:
⢠Homeostasis
⢠Metabolism,
⢠Growth & development,
⢠Water & electrolyte balance,
⢠Reproduction &
⢠Behaviour.
2
5. Types of Glands
1. Exocrine Glands
⢠Release their secretions through a
duct.
⢠These include :
⢠Sweat glands
⢠Salivary glands
⢠Pancreatic glands
⢠Mammary glands
Endocrine Glands
⢠Glands which have no duct.
⢠Release their secretions into the
ECF or into the blood.
⢠This include:
⢠Pituitary (AP & PP)
⢠Thyroid, Parathyroid
⢠Adrenal (cortex & medulla)
⢠Pancreas & Gonads
⢠Endocrine system consists
of gland, hormone,
transport, receptor, and
target cells.
5
6. Chemical classification of Hormones
1. Amines
⢠Hormones that are derived
from tyrosine.
⢠T4 & T3
⢠AD, NA
2. Peptides /proteins
⢠Hormones that are chains of
</>100 amino acids.
⢠ADH, Oxytocin,
⢠Insulin & human
growth hormone (GH).
3. Steroids
- Hormones that are lipids (cholesterol)
⢠Adrenal cortex (cortical
steroids)
⢠Gonads (sex steroids)
4. Eicosanoids
- Hormones that are lipids (FA).
⢠Prostaglandins
⢠Prostacyclins
⢠Thromboxanes
6
7. Hormone receptor and MoA
⢠Events developed after
complex formation are
changes on:
⢠Ion channel.
⢠Enzymatic activities.
⢠G protein & 2nd
messengers.
⢠Gene expression &
protein synthesis.
7
8. Hormone secretion control
⢠Hormone secretions are controlled by 4 methods:
1. Negative feedback mechanism (most hormones)
2. Positive feedback mechanism (LH- surge)
3. Neural control
⢠Secretion of OT, ADH, AD, NA
4. Circadian rhythm (periodic variations)
⢠Secretion of Sex hormones
8
9. Hypothalamus
⢠Is part of the diencephalon &about 5
gm.
⢠It plays most important role in
controlling homeostasis.
⢠It is the main brain structure
involved in regulating hormonal
levels in the body.
9
11. APG and PPG
ADH (vasopressin)
⢠Regulate body water &
BP by reabsorption of
water & vasoconstriction
of arteries and arterioles
⢠Oxytocin: contract
endometrial & breast
SM.
⢠Secretion from the gland
controlled by nerve signals.
11
⢠The AP lobe receives
hormones (RH & IH) from
the HT.
⢠No nerve fibers are
terminated in to APG.
⢠Secretion process is
regulated by blood born
hormones.
13. Growth hormones
⢠Promotes tissue growth by stimulating liver to
produce IGF-I/Somatomedin-C
⢠Promote protein synthesis
⢠Increase DNA transcription
⢠Increase mRNA production
⢠Enhance amino acids into cell & reduce protein
catabolism.
⢠Increase protein sparing, not used as energy.
13
14. Thyroid gland
⢠The largest endocrine gland
in the body.
⢠Positioned on the neck just
below the Larynx & has 2
lobes with one on either side
of the trachea.
⢠It produce hormones T3
(triiodothyronine) & T4
(thyroxine).
⢠T3 & T4 increase the
metabolic activity of the
bodyâs cells.
Function of the thyroid hormones
1. Calorigenic action
ď§ âO2 consumption
ď§ âMetabolic rate on CHO,
protein and Fat
ď§ Body growth: promotes
growth of bone, teeth and nerve
tissue in children
3. Effect on NS/CNS
ď§ Promotes growth and maturation
of nerve tissue, synaptic
development.
14
15. Calcitonin
⢠A hormone that is produced by the parafollicular cells (C-cells) of
the thyroid.
⢠Produced by the thyroid & contributes to the regulation of blood
ca+2 levels.
⢠Thyroid cells produce calcitonin in response to high ca+2 levels in
the blood:
⢠Decreases the concentration of ca+2 in the blood.
⢠This hormone will stimulate movement of calcium into the bone
structure.
15
16. Parathyroid gland
⢠Are 4 glands located on the
thyroid gland having
butterfly-shaped.
⢠Functions: Regulate the
body's calcium &
phosphorus levels.
⢠Secrete PTH [parathyroid
hormone], which
⢠Causes release of ca+2 from
bone to ECF.
⢠â Osteoblasts (production
of bone) &
⢠â Osteoclasts (removal of
bone).
⢠Signals the kidneys to
reabsorb ca+2 .
⢠Signals the small intestine to
absorb more ca+2
16
18. Adrenal glands
⢠Triangular-shaped glands located on
top of the kidneys.
⢠They regulate many essential
functions in the body, including:
â biochemical balances that
influence:
⢠Athletic training &
⢠General stress response.
⢠Produce hormones like:
â Aldosteron
â Cortisol
â Androgens
⢠Produces chemicals like:
â AD, NA
â Dopamine
18
19. Adrenal Cortex
1. Mineralocorticoids
(Aldosterone)
â regulate the salt & water
balance, leading to the increase
of BV & BP.
2. Glucocorticoids (Cortisol)
â raise blood glucose level,
stimulates breakdown of
protein.
3. Sex Hormones (Androgen)
â stimulates reproductive organs
& brings on sex characteristics.
Adrenal Medulla
⢠The effects of these hormones
provide a short-term
response to stress.
⢠Impulses from HT, spinal cord &
SNS fibers go to the adrenal
medulla,
⢠Then it releases hormones:
â Epinephrine
â Norepinephrine
19
Adrenal glands
20. Pancreas
⢠It is both an exocrine & an
endocrine organ.
⢠As an exocrine organ; it is
considered to be part of the
GIT.
⢠It produces digestive enzymes
to be released into the SI.
⢠Aid food digestion to
absorbable.
⢠Endocrine function.
⢠Secret Insulin & glucagon
⢠They are secreted by islet cells
released into the bloodstream.
⢠Groups of endocrine cells
(Islets of Langerhans) secrete
two hormones.
1. Beta cells [β]
⢠secrete Insulin
1. Alpha cells [â]
⢠secrete Glucagon.
20
21. ⢠Insulin
⢠Lower blood sugar levels
by allowing the sugar to
flow into cells.
⢠Glucagon
⢠Raise blood sugar levels
by causing glucose to be
released into the
circulation from its storage
sites.
⢠Insulin & glucagon act in an
opposite but balanced fashion
to keep blood sugar levels
stable.
1. On Carbohydrate
⢠ď¤blood glucose level by:
⢠Converting into glycogen
⢠Facilitate cells uptake
⢠Converting to fats & stored in the
adipose tissue
2. On Protein
â Promotes amino acid uptake by cells
and inhibits proteins breakdown.
3. On Cortisol
â Anti-cortisol effect =ď¤blood glucose by:
⢠inhibiting gluconeogenesis &
⢠activating glucose uptake
21
Insulin metabolic Effects