The endocrine system is comprised of glands that secrete hormones into the bloodstream to regulate various bodily functions like growth, stress response, and metabolism. The key glands include the pineal gland, hypothalamus, thyroid, parathyroid, pituitary gland, adrenal glands, pancreas, ovaries, and testes. The hypothalamus connects the endocrine and nervous systems by secreting neurohormones that stimulate or inhibit hormones from the pituitary gland, which then regulate other glands. Hormones and the nervous system interact through feedback and effects on neural processing and development.