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DIGESTION
AND
ABSORPTION
•1
•HSE Zoology blog
MAJOR COMPONENTS OF FOOD
• Carbohydrates
• Proteins
• Fats
• Vitamins
• Minerals
• Water
•2
•HSE Zoology blog
DIGESTION
• The process of
conversion of
complex food
substances to simple
absorbable form is
called digestion.
•3
•HSE Zoology blog
HUMAN DIGESTIVE
SYSTEM
Alimentary canal
Associated glands
•4
•HSE Zoology blog
DIGESTIVE
SYSTEM OF MAN
•5
•HSE Zoology blog
ORAL CAVITY
(BUCCAL CAVITY)
• Teeth
• Tongue
• Palate(roof)
•6
•HSE Zoology blog
Dentition
Refers the number, kinds and
arrangement of teeth
Thecodont
Heterodont
Diphyodont
TEETH
•7
•HSE Zoology blog
THECODONT
• Teeth are placed in
jaw sockets
•8
•HSE Zoology blog
HETERODONT
• Teeth are different types or dissimilar
Incisors
Canine
Premolars
Molars
•9
•HSE Zoology blog
DIPHYODONT
• Teeth appear twice in
the whole life
• Milk teeth
• Permanent teeth
•10
•HSE Zoology blog
The kind and number of teeth are explained in the
form of formula is called dental formula.
• Adult 32
permanent teeth
• Incisors 2/2
• Canine 1/1
• Premolars 2/2
• Molars 3/3
• Child 20 milk
teeth
• Incisors 2/2
• Canine 1/1
• Premolars 0/0
• Molars 2/2
DENTAL FORMULA
•11
•HSE Zoology blog
WISDOM TEETH
• Third molar appears
after the age of 20 years
and hence is called
wisdom teeth.
•12
•HSE Zoology blog
Odontoblast
Found in the dental
pulp secrete dentine
Crown
Neck
Root
STRUCTURE OF TOOTH
•13
•HSE Zoology blog
TONGUE
• Freely movable
muscular organ
attached to the floor of
the buccal cavity by
frenulum.
•14
•HSE Zoology blog
TONGUE
• The upper surface of
the tongue has small
projections called
papillae, some of
which bear taste
buds.
•15
•HSE Zoology blog
PHARYNX
• Common passage for
digestive and
respiratory system.
• Opening of oesophagus
• Opening of larynx -
Glottis
•16
•HSE Zoology blog
GLOTTIS
• Glottis is guarded by a
flap of tissue called
epiglottis.
• When food materials
pass through the
pharynx the epiglottis
closes the glottis.
•17
•HSE Zoology blog
OESOPHAGUS
• Narrow muscular tube
• 30 cm long
• Leads to stomach
• Pass through the
diaphragm (a muscular
partition that separates
thorax from abdomen).
•18
•HSE Zoology blog
OESOPHAGEAL SPHINCTER
(GASTRO OESOPHAGIAL SPHINCTER)
• Posterior region of the
oesophagus there is a
ring of muscle called
oesophagial sphincter.
• It controls the opening
of the oesophagus into
the stomach.
•19
•HSE Zoology blog
PERISTALSIS
• The movement of food
materials in the
esophagus is effected
by the wave like
contraction and
relaxation of
longitudinal and circular
muscles of the
esophagus is known as
peristalsis.
•20
•HSE Zoology blog
STOMACH
• Large muscular ‘J’
shaped sac.
• Lying just below the
diaphragm in the
abdominal cavity.
• Three major parts
– Cardiac
– Fundic
– Pyloric
•21
•HSE Zoology blog
PYLORIC SPHINCTER
• The opening of the
stomach into the
duodenum is guarded
by pyloric sphincter.
• Controls the flow of
food to the intestine.
•22
•HSE Zoology blog
SMALL INTESTINE
• Long, highly coiled,
narrow tube
• Seven metres long
• 2.5 cm diametre
• Divided in to
duodenum, jejunum &
ileum.
•23
•HSE Zoology blog
DUODENUM
• First part of SI
• ‘U’ shaped
• Area of digestion
• Receives common
opening of the bile
and pancreatic duct.
•24
•HSE Zoology blog
JEJUNUM
• Coiled and longer
•25
•HSE Zoology blog
ILEUM
• Highly coiled
• Opens into the large
intestine
• Area of absorption
•26
•HSE Zoology blog
LARGE INTESTINE
• 1.5 metres long
• Differentiated into
Caecum , Colon &
Rectum
•27
•HSE Zoology blog
CAECUM
• Small blind sac (at the
junction of SI &LI)
• Plays no role in Nutrient
absorption.
• It hosts some symbiotic
microorganisms.
• Caecum bears a finger like
out growth of unknown
function known as
Vermiform Appendix.
•28
•HSE Zoology blog
COLON
( Pelvic colon)
•29
•HSE Zoology blog
RECTUM
• Temporary storage of
faeces
• Rectum opens out by
Anus.
•30
•HSE Zoology blog
HISTOLOGY OF HUMAN GUT
( Outer most )
forms a fibrous coat
(Inner most)-made of
secretary & absorptive cells
Loose connective tissue layer
with blood & lymph vessels
Smooth muscle
•31
•HSE Zoology blog
RUGAE
• Mucosal layer forms
irregular fold in the
stomach called rugae.
•32
•HSE Zoology blog
VILLI
• (Sing:- Villus)
• Mucosal layer forms
small finger like
folding in the small
intestine called Villi
• A villus is about 0.5 to
1 mm long
Villus
•33
•HSE Zoology blog
VILLI
•34
•HSE Zoology blog
VILLI
•35
•HSE Zoology blog
VILLI
•36
•HSE Zoology blog
•37
•HSE Zoology blog
MICROVILLI
• Each villus has
numerous electron
microscopic
evaginations called
microvilli.
• Both villi & micro villi
increases the surface
area for digestion and
absorption of food
•38
•HSE Zoology blog
DIGESTIVE GLANDS
• Salivary glands
• Pancreas
• Liver
• Gastric glands
• Intestinal glands
•39
•HSE Zoology blog
DIGESTIVE ENZYMES
• Hydrolyses
Group of enzymes
released from the cells
digestive system play a
major role in the extra
cellular digestion in
human
• Carbohydrase (
amylase ) carbohydrate
digesting
E.g.: ptyalin, maltose etc
• Proteases (protein
digesting)
Eg: amino peptidase,
dipeptidase
. Lipase (lipid digesting)
•40
•HSE Zoology blog
SALIVARY GLANDS
• Secrete saliva
• Found in buccal cavity
• Three pairs of salivary
glands
1.Parotid glands
(largest)
2.Sub lingual glands
3.Sub maxillary
(Sub mandibular)
•41
•HSE Zoology blog
SALIVA
• Derived from blood plasma
• Secrete 1.5 liters of saliva
per day
• Slightly alkaline
• Contain water & electrolyte
(Na+, K+, Cl-, HCO3
-)
• Mucin, ptyalin, lyzozyme &
inorganic salts
• Ptyalin digest starch in to
maltose
•42
•HSE Zoology blog
LIVER
• Largest gland in the
human body
• Weighs about 1.5 kg in
adult man
• Bi lobed
• Secrete bile
•43
•HSE Zoology blog
• Each lobe is separated
into numerous tiny
hepatic lobules, which are
the functional units.
• A lobule is formed of
numerous hepatic cells –
bile is secreted by hepatic
cells
• Each lobule is covered by
a thin connective tissue
sheath called Glisson’s
capsule
Glisson’s
capsule
LIVER
•44
•HSE Zoology blog
HEPATIC LOBULES
•45
•HSE Zoology blog
GALL BLADDER
• Bile is stored and
Concentrated in a thin
muscular sac called
gall bladder.
• Capacity- 40 – 60 ml
• Absent in whale,
horses, rats etc.
•46
•HSE Zoology blog
BILE
• Golden yellow or greenish fluid
• Alkaline nature
• Bile pigments (product of dead RBC) (biliverdin & bilirubin)
• Bile salts,
• cholesterol,
• phospholipids
• Bile salts play a very important role in the emulsification of fat
•47
•HSE Zoology blog
GALL BLADDER
• The duct of gall
bladder (cystic duct)
along with hepatic
duct from the liver
forms a common bile
duct.
•48
•HSE Zoology blog
GALL BLADDER
• The bile duct and
pancreatic duct opens
together into the
duodenum as common
hepato - pancreatic
duct, which is guarded
by a sphincter called
sphincter of Oddi.
Hepato - Pancreatic duct •49
•HSE Zoology blog
PANCREAS
• Located between stomach
& duodenum
• Second largest glands
• Heterocrine gland (both
exocrine &endocrine)
• Pancreatic duct opens into
the duodenum along with
bile duct
• Secrete pancreatic juice.
•50
•HSE Zoology blog
PANCREATIC JUICE
• Alkaline nature
• Trypsinogen ,
Chymotrypsinogen
Proarboxypeptidase,
Amylopsin (p. amylase)
• Steapsin (pancreatic
lipase)
• Nuclease (Nucleic acid
digesting enzyme)
•51
•HSE Zoology blog
GASTRIC GLANDS
• Found on the wall of
stomach
• Formed of three kinds of
cells
1. Mucous cells
2. Chief cells or
Zymogen cells
3. Oxyntic cells
or Parital cells
•52
•HSE Zoology blog
mucus secreting
GASTRIC GLANDS
•53
•HSE Zoology blog
GASTRIC GLANDS
•54
•HSE Zoology blog
GASTRIC SECRETIONS
Name of Cell Function
Mucous cells (Goblet cells) Secrete mucous
Oxyntic cells or Parital cells
Secretion of HCl and intrensic
factor (factor essential for the
absorption of vitamin B12)
Chief cells or Zymogen cells
Secretion of enzymes such as
pepsin , rennin, lipase etc.
•55
•HSE Zoology blog
• Inactivate the secretion of
salivary amylase.
• Kills micro organism
• Lowers the pH of the
stomach (1.5 to 2.5)
• Activate proenzyme
pepsinogen to active pepsin.
HCl
•56
•HSE Zoology blog
INTESTINAL GLANDS
• Simple tubular glands found throughout SI
• Two types
Crypts of Lieberkuhn
Glands of Brunner
•57
•HSE Zoology blog
CRYPTS OF LIEBERKUHN
• Goblet cells – Mucous secreting
• Paneth cells – Enzyme secreting
Many surface area of gastro intestinal tract are
lined by evaginations of the epithelium in to sub
mucosa similar to pits. These pits of the
intestine are called Crypts of Lieberkuhn
Paneth cells
Goblet cells
villus
crypt
•58
•HSE Zoology blog
GLANDS OF BRUNNER ( DUODENAL GLANDS)
• Confined to the sub
mucosa of the
duodenum and
secrete mucus only
•59
•HSE Zoology blog
INTESTINAL JUICE
(SUCCUS ENTERICUS)
• Collective secretions of
intestinal glands
• Alkaline nature
• Contain enzymes ,
mucous & inorganic
salts.
• Proteases
Aminopeptidase,
Dipeptidase
• Amylase
Maltase, Isomaltase
Lactase, Surcease
• Lipase
• Enterokinase
•60
•HSE Zoology blog
DIGESTION
• The teeth and tongue with
the help of saliva masticate
and mix up the food into
bolus.
• The bolus is conveyed to
pharynx and then to
oesophagus by swallowing or
deglutition.
•61
•HSE Zoology blog
DIGESTION
• The stomach stores the food 4-5 hrs. The food
mixes thoroughly with acidic gastric juice to
form paste.- Chyme
chyme
•62
•HSE Zoology blog
• Starch
Maltose
Buccal cavity
Starch Maltose
Salivary amylase
CARBOHYDRATE
DIGESTION
Stomach
No carbohydrate
digestion
Small Intestine
Starch Maltose
Maltose 2 Glucose
Lactose Glucose +
Galactose
Sucrose Glucose +
Fructose
P. amylase
Maltase
Lactase
Sucrase
•63
•HSE Zoology blog
Buccal cavity
No protein digestion
Stomach
Pepsinogen Pepsin
HCl
Protein
Pepsin Peptones +
Proteoses
Peptones = larger peptides
Proteoses = smaller peptides
Small intestine
Trypsinogen Enterokinase Trypsin
Chymotrypsinogen Chymotrypsin
Procarboxy
peptidase
Carboxy
peptidase
Proteins
Peptones
Proteoses
Dipeptides
Dipeptides Amino acids
Dipeptidase
Trypsin / Chymotrypsin
Carboxy peptidase
PROTEIN DIGESTION
•64
•HSE Zoology blog
Buccal cavity
No protein digestion
Stomach
Gastric lipase hydrolyses
only a small amount of
fat Small intestine
Fat Fat droplets
Bile
Emulsification
Fat
Pancreatic lipase
Fatty acids & Glycerol
Diglyceride
Monoglycerides
FAT DIGESTION
•65
•HSE Zoology blog
Small Intestine
Nucleic acids Nucleotides Nucleosides Sugar + Bases
NUCLEIC ACID DIGESTION
•66
•HSE Zoology blog
END PRODUCTS OF DIGESTION
Carbohydrates
Glucose
Fructose
Galactose
Proteins
Amino acids
Fats
Fatty acids
glycerol
•67
•HSE Zoology blog
• Complete digestion of
food take place in the
duodenum. The fully
digested food is semi
fluid in nature and is
known as Chyle
DIGESTION
•68
•HSE Zoology blog
ABSORPTION OF DIGESTED PRODUCTS
• Absorption is the process by
which the end products of
digestion pass through the
intestinal mucosa
( transported through the
intestinal mucosa) into the
blood or lymph
• The end products of digestion
are absorbed in the jejunum
and ileum regions of small
intestine.
•69
•HSE Zoology blog
Absorption is carried out by
– Passive transport
– Facilitated transport
– Active transport
ABSORPTION
•70
•HSE Zoology blog
PASSIVE TRANSPORT
• Small amounts of monosaccharide like glucose, amino acids,
and some of electrolytes like chloride ions are generally
absorbed by simple diffusion.
•71
•HSE Zoology blog
•72
•HSE Zoology blog
FACILITATED TRANSPORT
• Fructose and some
amino acids are
absorbed with the help
of carrier ions like
sodium. This
mechanism is called
facilitated transport.
•73
•HSE Zoology blog
ACTIVE TRANSPORT
• Requires energy
• Various nutrients like
amino acids,
monosaccharide like
glucose, electrolytes like
Na+ are reabsorbed into
the blood by active
transport.
•74
•HSE Zoology blog
•75
•HSE Zoology blog
ABSORPTION OF FAT
• Fatty acids and glycerol insoluble in water so they cannot be
absorbed directly from the lumen of the intestine.
• With the help of bile salts & phospholipids the fatty acids and
glycerol are converted into small spherical water soluble droplets
called micelles.
•76
•HSE Zoology blog
ABSORPTION OF FAT
Micelles are reformed into very small protein coated fat
globules called chylomicrons. Which are transported in to
the lymph vessels (lactales)in the villi.
•77
•HSE Zoology blog
ABSORPTION OF FAT
•78
•HSE Zoology blog
LARGE INTESTINE
Functions
Absorption of water,
minerals and certain
drugs.
Secretion of mucus which
helps in adhering waste.
• No significant digestive
activity occurs in the
large intestine.
•79
•HSE Zoology blog
LARGE INTESTINE
• The undigested and
unabsorbed substances
(faeces) enters into the
caecum of the large
intestine through the
ileo caecal valve, which
prevents the back flow
of faecal matter.
•80
•HSE Zoology blog
EGESTION
• The egestion of faeces
to the outside through
the anal opening
(defaecation) is a
voluntary process and is
carried out by a mass
peristaltic movement.
•81
•HSE Zoology blog
THE SUMMARY OF ABSORPTION IN DIFFERENT PARTS OF
DIGESTIVE SYSTEM
Oral cavity Stomach Small Intestine Large
Intestine
Certain drugs
coming in
contact with the
mucosa of the
mouth and
lower side of the
tongue are
absorbed into
the blood
capillaries lining
them.
Water, simple
sugars, alcohol
Glucose Fructose
Fatty acids
Glycerol
Amino acids
Water , some
minerals,
drugs
•82
•HSE Zoology blog
DISORDERS OF DIGESTIVE SYSTEM
• Infections of the
digestive system
are caused by
bacteria, virus,
parasites like tape
worm, thread
worm, round
worm, hook
worm, pinworm
etc.
Bacteria
Tape worm
Virus
Pinworm
Thread worm
•83
•HSE Zoology blog
VOMITING
• It is the ejection of stomach
content through the mouth.
•84
•HSE Zoology blog
DIARRHOEA
• The abnormal
frequency of bowel
movement and
increased liquidity of
faecal discharge is
known as diarrhoea.
• It reduces the
absorption of food.
•85
•HSE Zoology blog
JAUNDICE
• The liver is affected, skin, eyes turn
yellow due to the deposition of bile
pigments.
•86
•HSE Zoology blog
CONSTIPATION
• The faeces are retained
with in the rectum as
the bowel movement
occur irregularly.
•87
•HSE Zoology blog
INDIGESTION
• The food is not properly
digested leading to the
feeling of fullness.
• The cause of indigestion
are inadequate enzyme
secretion, anxiety, food
poisoning, overeating
and spicy food.
•88
•HSE Zoology blog

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  • 2. MAJOR COMPONENTS OF FOOD • Carbohydrates • Proteins • Fats • Vitamins • Minerals • Water •2 •HSE Zoology blog
  • 3. DIGESTION • The process of conversion of complex food substances to simple absorbable form is called digestion. •3 •HSE Zoology blog
  • 4. HUMAN DIGESTIVE SYSTEM Alimentary canal Associated glands •4 •HSE Zoology blog
  • 6. ORAL CAVITY (BUCCAL CAVITY) • Teeth • Tongue • Palate(roof) •6 •HSE Zoology blog
  • 7. Dentition Refers the number, kinds and arrangement of teeth Thecodont Heterodont Diphyodont TEETH •7 •HSE Zoology blog
  • 8. THECODONT • Teeth are placed in jaw sockets •8 •HSE Zoology blog
  • 9. HETERODONT • Teeth are different types or dissimilar Incisors Canine Premolars Molars •9 •HSE Zoology blog
  • 10. DIPHYODONT • Teeth appear twice in the whole life • Milk teeth • Permanent teeth •10 •HSE Zoology blog
  • 11. The kind and number of teeth are explained in the form of formula is called dental formula. • Adult 32 permanent teeth • Incisors 2/2 • Canine 1/1 • Premolars 2/2 • Molars 3/3 • Child 20 milk teeth • Incisors 2/2 • Canine 1/1 • Premolars 0/0 • Molars 2/2 DENTAL FORMULA •11 •HSE Zoology blog
  • 12. WISDOM TEETH • Third molar appears after the age of 20 years and hence is called wisdom teeth. •12 •HSE Zoology blog
  • 13. Odontoblast Found in the dental pulp secrete dentine Crown Neck Root STRUCTURE OF TOOTH •13 •HSE Zoology blog
  • 14. TONGUE • Freely movable muscular organ attached to the floor of the buccal cavity by frenulum. •14 •HSE Zoology blog
  • 15. TONGUE • The upper surface of the tongue has small projections called papillae, some of which bear taste buds. •15 •HSE Zoology blog
  • 16. PHARYNX • Common passage for digestive and respiratory system. • Opening of oesophagus • Opening of larynx - Glottis •16 •HSE Zoology blog
  • 17. GLOTTIS • Glottis is guarded by a flap of tissue called epiglottis. • When food materials pass through the pharynx the epiglottis closes the glottis. •17 •HSE Zoology blog
  • 18. OESOPHAGUS • Narrow muscular tube • 30 cm long • Leads to stomach • Pass through the diaphragm (a muscular partition that separates thorax from abdomen). •18 •HSE Zoology blog
  • 19. OESOPHAGEAL SPHINCTER (GASTRO OESOPHAGIAL SPHINCTER) • Posterior region of the oesophagus there is a ring of muscle called oesophagial sphincter. • It controls the opening of the oesophagus into the stomach. •19 •HSE Zoology blog
  • 20. PERISTALSIS • The movement of food materials in the esophagus is effected by the wave like contraction and relaxation of longitudinal and circular muscles of the esophagus is known as peristalsis. •20 •HSE Zoology blog
  • 21. STOMACH • Large muscular ‘J’ shaped sac. • Lying just below the diaphragm in the abdominal cavity. • Three major parts – Cardiac – Fundic – Pyloric •21 •HSE Zoology blog
  • 22. PYLORIC SPHINCTER • The opening of the stomach into the duodenum is guarded by pyloric sphincter. • Controls the flow of food to the intestine. •22 •HSE Zoology blog
  • 23. SMALL INTESTINE • Long, highly coiled, narrow tube • Seven metres long • 2.5 cm diametre • Divided in to duodenum, jejunum & ileum. •23 •HSE Zoology blog
  • 24. DUODENUM • First part of SI • ‘U’ shaped • Area of digestion • Receives common opening of the bile and pancreatic duct. •24 •HSE Zoology blog
  • 25. JEJUNUM • Coiled and longer •25 •HSE Zoology blog
  • 26. ILEUM • Highly coiled • Opens into the large intestine • Area of absorption •26 •HSE Zoology blog
  • 27. LARGE INTESTINE • 1.5 metres long • Differentiated into Caecum , Colon & Rectum •27 •HSE Zoology blog
  • 28. CAECUM • Small blind sac (at the junction of SI &LI) • Plays no role in Nutrient absorption. • It hosts some symbiotic microorganisms. • Caecum bears a finger like out growth of unknown function known as Vermiform Appendix. •28 •HSE Zoology blog
  • 30. RECTUM • Temporary storage of faeces • Rectum opens out by Anus. •30 •HSE Zoology blog
  • 31. HISTOLOGY OF HUMAN GUT ( Outer most ) forms a fibrous coat (Inner most)-made of secretary & absorptive cells Loose connective tissue layer with blood & lymph vessels Smooth muscle •31 •HSE Zoology blog
  • 32. RUGAE • Mucosal layer forms irregular fold in the stomach called rugae. •32 •HSE Zoology blog
  • 33. VILLI • (Sing:- Villus) • Mucosal layer forms small finger like folding in the small intestine called Villi • A villus is about 0.5 to 1 mm long Villus •33 •HSE Zoology blog
  • 38. MICROVILLI • Each villus has numerous electron microscopic evaginations called microvilli. • Both villi & micro villi increases the surface area for digestion and absorption of food •38 •HSE Zoology blog
  • 39. DIGESTIVE GLANDS • Salivary glands • Pancreas • Liver • Gastric glands • Intestinal glands •39 •HSE Zoology blog
  • 40. DIGESTIVE ENZYMES • Hydrolyses Group of enzymes released from the cells digestive system play a major role in the extra cellular digestion in human • Carbohydrase ( amylase ) carbohydrate digesting E.g.: ptyalin, maltose etc • Proteases (protein digesting) Eg: amino peptidase, dipeptidase . Lipase (lipid digesting) •40 •HSE Zoology blog
  • 41. SALIVARY GLANDS • Secrete saliva • Found in buccal cavity • Three pairs of salivary glands 1.Parotid glands (largest) 2.Sub lingual glands 3.Sub maxillary (Sub mandibular) •41 •HSE Zoology blog
  • 42. SALIVA • Derived from blood plasma • Secrete 1.5 liters of saliva per day • Slightly alkaline • Contain water & electrolyte (Na+, K+, Cl-, HCO3 -) • Mucin, ptyalin, lyzozyme & inorganic salts • Ptyalin digest starch in to maltose •42 •HSE Zoology blog
  • 43. LIVER • Largest gland in the human body • Weighs about 1.5 kg in adult man • Bi lobed • Secrete bile •43 •HSE Zoology blog
  • 44. • Each lobe is separated into numerous tiny hepatic lobules, which are the functional units. • A lobule is formed of numerous hepatic cells – bile is secreted by hepatic cells • Each lobule is covered by a thin connective tissue sheath called Glisson’s capsule Glisson’s capsule LIVER •44 •HSE Zoology blog
  • 46. GALL BLADDER • Bile is stored and Concentrated in a thin muscular sac called gall bladder. • Capacity- 40 – 60 ml • Absent in whale, horses, rats etc. •46 •HSE Zoology blog
  • 47. BILE • Golden yellow or greenish fluid • Alkaline nature • Bile pigments (product of dead RBC) (biliverdin & bilirubin) • Bile salts, • cholesterol, • phospholipids • Bile salts play a very important role in the emulsification of fat •47 •HSE Zoology blog
  • 48. GALL BLADDER • The duct of gall bladder (cystic duct) along with hepatic duct from the liver forms a common bile duct. •48 •HSE Zoology blog
  • 49. GALL BLADDER • The bile duct and pancreatic duct opens together into the duodenum as common hepato - pancreatic duct, which is guarded by a sphincter called sphincter of Oddi. Hepato - Pancreatic duct •49 •HSE Zoology blog
  • 50. PANCREAS • Located between stomach & duodenum • Second largest glands • Heterocrine gland (both exocrine &endocrine) • Pancreatic duct opens into the duodenum along with bile duct • Secrete pancreatic juice. •50 •HSE Zoology blog
  • 51. PANCREATIC JUICE • Alkaline nature • Trypsinogen , Chymotrypsinogen Proarboxypeptidase, Amylopsin (p. amylase) • Steapsin (pancreatic lipase) • Nuclease (Nucleic acid digesting enzyme) •51 •HSE Zoology blog
  • 52. GASTRIC GLANDS • Found on the wall of stomach • Formed of three kinds of cells 1. Mucous cells 2. Chief cells or Zymogen cells 3. Oxyntic cells or Parital cells •52 •HSE Zoology blog
  • 55. GASTRIC SECRETIONS Name of Cell Function Mucous cells (Goblet cells) Secrete mucous Oxyntic cells or Parital cells Secretion of HCl and intrensic factor (factor essential for the absorption of vitamin B12) Chief cells or Zymogen cells Secretion of enzymes such as pepsin , rennin, lipase etc. •55 •HSE Zoology blog
  • 56. • Inactivate the secretion of salivary amylase. • Kills micro organism • Lowers the pH of the stomach (1.5 to 2.5) • Activate proenzyme pepsinogen to active pepsin. HCl •56 •HSE Zoology blog
  • 57. INTESTINAL GLANDS • Simple tubular glands found throughout SI • Two types Crypts of Lieberkuhn Glands of Brunner •57 •HSE Zoology blog
  • 58. CRYPTS OF LIEBERKUHN • Goblet cells – Mucous secreting • Paneth cells – Enzyme secreting Many surface area of gastro intestinal tract are lined by evaginations of the epithelium in to sub mucosa similar to pits. These pits of the intestine are called Crypts of Lieberkuhn Paneth cells Goblet cells villus crypt •58 •HSE Zoology blog
  • 59. GLANDS OF BRUNNER ( DUODENAL GLANDS) • Confined to the sub mucosa of the duodenum and secrete mucus only •59 •HSE Zoology blog
  • 60. INTESTINAL JUICE (SUCCUS ENTERICUS) • Collective secretions of intestinal glands • Alkaline nature • Contain enzymes , mucous & inorganic salts. • Proteases Aminopeptidase, Dipeptidase • Amylase Maltase, Isomaltase Lactase, Surcease • Lipase • Enterokinase •60 •HSE Zoology blog
  • 61. DIGESTION • The teeth and tongue with the help of saliva masticate and mix up the food into bolus. • The bolus is conveyed to pharynx and then to oesophagus by swallowing or deglutition. •61 •HSE Zoology blog
  • 62. DIGESTION • The stomach stores the food 4-5 hrs. The food mixes thoroughly with acidic gastric juice to form paste.- Chyme chyme •62 •HSE Zoology blog
  • 63. • Starch Maltose Buccal cavity Starch Maltose Salivary amylase CARBOHYDRATE DIGESTION Stomach No carbohydrate digestion Small Intestine Starch Maltose Maltose 2 Glucose Lactose Glucose + Galactose Sucrose Glucose + Fructose P. amylase Maltase Lactase Sucrase •63 •HSE Zoology blog
  • 64. Buccal cavity No protein digestion Stomach Pepsinogen Pepsin HCl Protein Pepsin Peptones + Proteoses Peptones = larger peptides Proteoses = smaller peptides Small intestine Trypsinogen Enterokinase Trypsin Chymotrypsinogen Chymotrypsin Procarboxy peptidase Carboxy peptidase Proteins Peptones Proteoses Dipeptides Dipeptides Amino acids Dipeptidase Trypsin / Chymotrypsin Carboxy peptidase PROTEIN DIGESTION •64 •HSE Zoology blog
  • 65. Buccal cavity No protein digestion Stomach Gastric lipase hydrolyses only a small amount of fat Small intestine Fat Fat droplets Bile Emulsification Fat Pancreatic lipase Fatty acids & Glycerol Diglyceride Monoglycerides FAT DIGESTION •65 •HSE Zoology blog
  • 66. Small Intestine Nucleic acids Nucleotides Nucleosides Sugar + Bases NUCLEIC ACID DIGESTION •66 •HSE Zoology blog
  • 67. END PRODUCTS OF DIGESTION Carbohydrates Glucose Fructose Galactose Proteins Amino acids Fats Fatty acids glycerol •67 •HSE Zoology blog
  • 68. • Complete digestion of food take place in the duodenum. The fully digested food is semi fluid in nature and is known as Chyle DIGESTION •68 •HSE Zoology blog
  • 69. ABSORPTION OF DIGESTED PRODUCTS • Absorption is the process by which the end products of digestion pass through the intestinal mucosa ( transported through the intestinal mucosa) into the blood or lymph • The end products of digestion are absorbed in the jejunum and ileum regions of small intestine. •69 •HSE Zoology blog
  • 70. Absorption is carried out by – Passive transport – Facilitated transport – Active transport ABSORPTION •70 •HSE Zoology blog
  • 71. PASSIVE TRANSPORT • Small amounts of monosaccharide like glucose, amino acids, and some of electrolytes like chloride ions are generally absorbed by simple diffusion. •71 •HSE Zoology blog
  • 73. FACILITATED TRANSPORT • Fructose and some amino acids are absorbed with the help of carrier ions like sodium. This mechanism is called facilitated transport. •73 •HSE Zoology blog
  • 74. ACTIVE TRANSPORT • Requires energy • Various nutrients like amino acids, monosaccharide like glucose, electrolytes like Na+ are reabsorbed into the blood by active transport. •74 •HSE Zoology blog
  • 76. ABSORPTION OF FAT • Fatty acids and glycerol insoluble in water so they cannot be absorbed directly from the lumen of the intestine. • With the help of bile salts & phospholipids the fatty acids and glycerol are converted into small spherical water soluble droplets called micelles. •76 •HSE Zoology blog
  • 77. ABSORPTION OF FAT Micelles are reformed into very small protein coated fat globules called chylomicrons. Which are transported in to the lymph vessels (lactales)in the villi. •77 •HSE Zoology blog
  • 79. LARGE INTESTINE Functions Absorption of water, minerals and certain drugs. Secretion of mucus which helps in adhering waste. • No significant digestive activity occurs in the large intestine. •79 •HSE Zoology blog
  • 80. LARGE INTESTINE • The undigested and unabsorbed substances (faeces) enters into the caecum of the large intestine through the ileo caecal valve, which prevents the back flow of faecal matter. •80 •HSE Zoology blog
  • 81. EGESTION • The egestion of faeces to the outside through the anal opening (defaecation) is a voluntary process and is carried out by a mass peristaltic movement. •81 •HSE Zoology blog
  • 82. THE SUMMARY OF ABSORPTION IN DIFFERENT PARTS OF DIGESTIVE SYSTEM Oral cavity Stomach Small Intestine Large Intestine Certain drugs coming in contact with the mucosa of the mouth and lower side of the tongue are absorbed into the blood capillaries lining them. Water, simple sugars, alcohol Glucose Fructose Fatty acids Glycerol Amino acids Water , some minerals, drugs •82 •HSE Zoology blog
  • 83. DISORDERS OF DIGESTIVE SYSTEM • Infections of the digestive system are caused by bacteria, virus, parasites like tape worm, thread worm, round worm, hook worm, pinworm etc. Bacteria Tape worm Virus Pinworm Thread worm •83 •HSE Zoology blog
  • 84. VOMITING • It is the ejection of stomach content through the mouth. •84 •HSE Zoology blog
  • 85. DIARRHOEA • The abnormal frequency of bowel movement and increased liquidity of faecal discharge is known as diarrhoea. • It reduces the absorption of food. •85 •HSE Zoology blog
  • 86. JAUNDICE • The liver is affected, skin, eyes turn yellow due to the deposition of bile pigments. •86 •HSE Zoology blog
  • 87. CONSTIPATION • The faeces are retained with in the rectum as the bowel movement occur irregularly. •87 •HSE Zoology blog
  • 88. INDIGESTION • The food is not properly digested leading to the feeling of fullness. • The cause of indigestion are inadequate enzyme secretion, anxiety, food poisoning, overeating and spicy food. •88 •HSE Zoology blog