This daily lesson plan outlines a science class that will teach 10th grade students about nucleic acids. The lesson will begin with an activity to review carbohydrates and an introductory puzzle. Students will then work in groups to differentiate between DNA and RNA using pictures and descriptions. They will discuss the structures, sugars, bases, and functions of DNA and RNA. An nucleic acid song will be used to generalize learning. The lesson will conclude with a multiple choice assessment and an assignment on lipids and proteins. The teacher will reflect on student understanding and require additional activities as needed.