The document provides an in-depth overview of atopic dermatitis (AD), including its pathogenesis, clinical presentation, systemic immune response, and treatment approaches. It discusses several theories for its pathogenesis, including abnormalities in cyclic adenosine monophosphate signaling, the allergy hypothesis involving TH2 cell responses, and genetic factors like filaggrin gene mutations. Diagnosis involves characteristic clinical features along with personal or family history of atopy. Management focuses on emollients, topical corticosteroids, antibiotics, phototherapy, immunomodulators, and avoidance of triggers.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Vitiligo : What's new in 2012 - Howard Fox Memorial Lecture, New York Academy...VR Foundation
NYAM Section on Dermatology Presents the 2012 Howard Fox, MD Memorial Lecture
Date: March 13, 2012 to March 13, 2012
Time: 6:00 PM - 8:00 PM p.m., Lecture 7:00 p.m. – 8:00 p.m.
Speaker(s): Torello Lotti, MD, Professor of the Dermatology and Venereology Division at Guglielmo Marconi University, Rome, Italy - Honorary Professor of Dermatology - China Medical University Shenyang, 18 Dec.2011
Chair, Executive Scientific Committee Vitiligo Research Foundation, New York , NY , USA.
Sponsored by: NYAM Section on Dermatology
Location: The New York Academy of Medicine, 1216 Fifth Avenue at 103rd Street, New York, NY 10029
"Vitiligo: What's New – Update in 2012"
Vitiligo is a chronic acquired hypomelanotic disorder affecting 0.5-2% of the world's population. Different forms of vitiligo have been described, according to the distribution and the extent of the achromic lesion. Several hypotheses have been proposed to explain the pathogenesis of vitiligo. The two major pathogenetic hypotheses are focused on immune-mediated or toxic-mediated cell damage primarily directed at melanocytes. New data demonstrated an important involvement of the keratinocytes and dendritic cells in the pathogenesis of vitiligo.
According to our progress in understanding Vitiligo pathogenesis, new and experimental therapies, such as narrow-band ultraviolet B microphototherapy (NB-UVB), narrow-band ultraviolet B excimer laser and monochromatic excimer light are available for the treatment of the disease. In addition, there are new topical treatments such as antioxidants, tacrolimus and pimecrolimus, prostaglandin E, and vitamin D derivatives. Excellent therapeutic results can be achieved through combination treatments.
About the Speaker(s)
Torello Lotti, MD, Prof. Lotti is Professor of the Dermatology and Venereology Division at Guglielmo Marconi University, Rome, Italy. Previously, he was Professor of the Dermatology and Venereology Division at University of Florence School of Medicine, Florence, Italy.
The fields of his principal scientific investigations are focused on the study of neuropeptides in numerous skin diseases, of plasminogen activators in autoimmune dermatoses and in lichen planus, and the clinical aspects and treatment of psoriasis vulgaris with particular emphasis on new therapies with biological agents. Of particular relevance is his research on the pathogenesis and innovative treatments for vitiligo.
Dr. Lotti is Visiting Professor and Director, International Centre for Balneology, Cell Biology, and Physiotherapy, Thomas Jefferson University, Philadelphia (PA, USA), Visiting Professor of Dermatology in six international universities, and Key Note Lecturer, Japanese Society of Cosmetic Dermatology. Past activities: Past-President of the Italian Society of Dermatology and Venereology, Past President of International Society of Dermatology.
Vitiligo : What's new in 2012 - Howard Fox Memorial Lecture, New York Academy...VR Foundation
NYAM Section on Dermatology Presents the 2012 Howard Fox, MD Memorial Lecture
Date: March 13, 2012 to March 13, 2012
Time: 6:00 PM - 8:00 PM p.m., Lecture 7:00 p.m. – 8:00 p.m.
Speaker(s): Torello Lotti, MD, Professor of the Dermatology and Venereology Division at Guglielmo Marconi University, Rome, Italy - Honorary Professor of Dermatology - China Medical University Shenyang, 18 Dec.2011
Chair, Executive Scientific Committee Vitiligo Research Foundation, New York , NY , USA.
Sponsored by: NYAM Section on Dermatology
Location: The New York Academy of Medicine, 1216 Fifth Avenue at 103rd Street, New York, NY 10029
"Vitiligo: What's New – Update in 2012"
Vitiligo is a chronic acquired hypomelanotic disorder affecting 0.5-2% of the world's population. Different forms of vitiligo have been described, according to the distribution and the extent of the achromic lesion. Several hypotheses have been proposed to explain the pathogenesis of vitiligo. The two major pathogenetic hypotheses are focused on immune-mediated or toxic-mediated cell damage primarily directed at melanocytes. New data demonstrated an important involvement of the keratinocytes and dendritic cells in the pathogenesis of vitiligo.
According to our progress in understanding Vitiligo pathogenesis, new and experimental therapies, such as narrow-band ultraviolet B microphototherapy (NB-UVB), narrow-band ultraviolet B excimer laser and monochromatic excimer light are available for the treatment of the disease. In addition, there are new topical treatments such as antioxidants, tacrolimus and pimecrolimus, prostaglandin E, and vitamin D derivatives. Excellent therapeutic results can be achieved through combination treatments.
About the Speaker(s)
Torello Lotti, MD, Prof. Lotti is Professor of the Dermatology and Venereology Division at Guglielmo Marconi University, Rome, Italy. Previously, he was Professor of the Dermatology and Venereology Division at University of Florence School of Medicine, Florence, Italy.
The fields of his principal scientific investigations are focused on the study of neuropeptides in numerous skin diseases, of plasminogen activators in autoimmune dermatoses and in lichen planus, and the clinical aspects and treatment of psoriasis vulgaris with particular emphasis on new therapies with biological agents. Of particular relevance is his research on the pathogenesis and innovative treatments for vitiligo.
Dr. Lotti is Visiting Professor and Director, International Centre for Balneology, Cell Biology, and Physiotherapy, Thomas Jefferson University, Philadelphia (PA, USA), Visiting Professor of Dermatology in six international universities, and Key Note Lecturer, Japanese Society of Cosmetic Dermatology. Past activities: Past-President of the Italian Society of Dermatology and Venereology, Past President of International Society of Dermatology.
Essentials of Automations: Optimizing FME Workflows with ParametersSafe Software
Are you looking to streamline your workflows and boost your projects’ efficiency? Do you find yourself searching for ways to add flexibility and control over your FME workflows? If so, you’re in the right place.
Join us for an insightful dive into the world of FME parameters, a critical element in optimizing workflow efficiency. This webinar marks the beginning of our three-part “Essentials of Automation” series. This first webinar is designed to equip you with the knowledge and skills to utilize parameters effectively: enhancing the flexibility, maintainability, and user control of your FME projects.
Here’s what you’ll gain:
- Essentials of FME Parameters: Understand the pivotal role of parameters, including Reader/Writer, Transformer, User, and FME Flow categories. Discover how they are the key to unlocking automation and optimization within your workflows.
- Practical Applications in FME Form: Delve into key user parameter types including choice, connections, and file URLs. Allow users to control how a workflow runs, making your workflows more reusable. Learn to import values and deliver the best user experience for your workflows while enhancing accuracy.
- Optimization Strategies in FME Flow: Explore the creation and strategic deployment of parameters in FME Flow, including the use of deployment and geometry parameters, to maximize workflow efficiency.
- Pro Tips for Success: Gain insights on parameterizing connections and leveraging new features like Conditional Visibility for clarity and simplicity.
We’ll wrap up with a glimpse into future webinars, followed by a Q&A session to address your specific questions surrounding this topic.
Don’t miss this opportunity to elevate your FME expertise and drive your projects to new heights of efficiency.
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Generating a custom Ruby SDK for your web service or Rails API using Smithyg2nightmarescribd
Have you ever wanted a Ruby client API to communicate with your web service? Smithy is a protocol-agnostic language for defining services and SDKs. Smithy Ruby is an implementation of Smithy that generates a Ruby SDK using a Smithy model. In this talk, we will explore Smithy and Smithy Ruby to learn how to generate custom feature-rich SDKs that can communicate with any web service, such as a Rails JSON API.
GraphRAG is All You need? LLM & Knowledge GraphGuy Korland
Guy Korland, CEO and Co-founder of FalkorDB, will review two articles on the integration of language models with knowledge graphs.
1. Unifying Large Language Models and Knowledge Graphs: A Roadmap.
https://arxiv.org/abs/2306.08302
2. Microsoft Research's GraphRAG paper and a review paper on various uses of knowledge graphs:
https://www.microsoft.com/en-us/research/blog/graphrag-unlocking-llm-discovery-on-narrative-private-data/
JMeter webinar - integration with InfluxDB and GrafanaRTTS
Watch this recorded webinar about real-time monitoring of application performance. See how to integrate Apache JMeter, the open-source leader in performance testing, with InfluxDB, the open-source time-series database, and Grafana, the open-source analytics and visualization application.
In this webinar, we will review the benefits of leveraging InfluxDB and Grafana when executing load tests and demonstrate how these tools are used to visualize performance metrics.
Length: 30 minutes
Session Overview
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During this webinar, we will cover the following topics while demonstrating the integrations of JMeter, InfluxDB and Grafana:
- What out-of-the-box solutions are available for real-time monitoring JMeter tests?
- What are the benefits of integrating InfluxDB and Grafana into the load testing stack?
- Which features are provided by Grafana?
- Demonstration of InfluxDB and Grafana using a practice web application
To view the webinar recording, go to:
https://www.rttsweb.com/jmeter-integration-webinar
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024Tobias Schneck
As AI technology is pushing into IT I was wondering myself, as an “infrastructure container kubernetes guy”, how get this fancy AI technology get managed from an infrastructure operational view? Is it possible to apply our lovely cloud native principals as well? What benefit’s both technologies could bring to each other?
Let me take this questions and provide you a short journey through existing deployment models and use cases for AI software. On practical examples, we discuss what cloud/on-premise strategy we may need for applying it to our own infrastructure to get it to work from an enterprise perspective. I want to give an overview about infrastructure requirements and technologies, what could be beneficial or limiting your AI use cases in an enterprise environment. An interactive Demo will give you some insides, what approaches I got already working for real.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Accelerate your Kubernetes clusters with Varnish CachingThijs Feryn
A presentation about the usage and availability of Varnish on Kubernetes. This talk explores the capabilities of Varnish caching and shows how to use the Varnish Helm chart to deploy it to Kubernetes.
This presentation was delivered at K8SUG Singapore. See https://feryn.eu/presentations/accelerate-your-kubernetes-clusters-with-varnish-caching-k8sug-singapore-28-2024 for more details.
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
34. Proposed criteria for the diagnosis of AD. Keratoconus Anterior capsular cataracts Palmar hyperlinearity Morgan-Dennie lines Allergic shiners Vascular instability Pityriasis alba Eczematous lesions Keratosis pilaris Pruritus Xerosis Atopy (personal or family history) Nonessential Essential
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38. DIFFERENTIAL DIGNOSIS of AD History of recurrent infection Immunodeficiency disorder Serpiginous plaques with central clearing, positive potassium hydroxide preparation Dermatophyte infection Vesicles over extensor areas and associated enteropathy Dermatitis herpetiformis Findings on complete history and physical examination vary by disease Systemic diseases Papules, finger web involvement, positive skin scraping Scabies Positive exposure history, rash in area of exposure, absence of family history Contact dermatitis Usually, a single patch in an area accessible to itching; absence of family history Neurodermatitis Localized patches on extensor surfaces, scalp, buttocks; pitted nails Psoriasis