The document summarizes key anatomical structures of the petrous bone including:
- The trigeminal depression and arcuate eminence on the superior surface.
- The subarcuate fossa, vestibular aqueduct, and cochlear canaliculus on the medial surface.
- The jugular foramen located where the petrous bone meets the occipital bone and contains compartments for neural and vascular structures.
a basic description of temporal bone anatomy which is necessary for primary radiologic evaluation of temporal bone imaging and some important points and differential diagnoses in related imaging.
a basic description of temporal bone anatomy which is necessary for primary radiologic evaluation of temporal bone imaging and some important points and differential diagnoses in related imaging.
Skull base tumors & perineural spread radiology pptDr pradeep Kumar
Skull base tumors & perineural spread radiology ppt This powerpoint presentation includes important anatomy and important pathology of skull base lesion with its imaging feature as well as its ct mri image. This will help alot. this will help for radiology resident as well as ent .
Skull base tumors & perineural spread radiology pptDr pradeep Kumar
Skull base tumors & perineural spread radiology ppt This powerpoint presentation includes important anatomy and important pathology of skull base lesion with its imaging feature as well as its ct mri image. This will help alot. this will help for radiology resident as well as ent .
Detecting Early Liver Fibrosis - A Nutshell for Primary CareJarrod Lee
This presentation summarizes the latest technologies for detecting early liver fibrosis and their role in healthcare today. It is aimed at primary care doctors, to help them better utilize these new developments for their patients.
Overview of role of imaging in different intraconal and extraconal pathologies including infective,inflammatory and neoplastic pathologies.Also included is insight into anatomy,trauma,post operative imaging and certain miscellaneous disorders
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
27. References
Hugh D. Curtin, James D. Rabinov and Peter M. Som
(2003): Central Skull Base: Embryology Anatomy, and
Pathology in Central skull base in Head and Neck
Imaging. Peter M. Som & Hugh D. Curt (edit)
Mosby, Inc. St. Louis, Chapter 12 FOURTH EDITION.
Volume one 785- 863
Editor's Notes
The superior surface of petrosal part of temporal bone: Middle fossa surface of petrous part of temporal bone called tegmen. It contains vestibular and cochlear labrynth. It roofs carotid canal, EA canal, facial canal, & tympanic cavity. It has following surface landmarks: 1) Trigeminal impression:: on the upper surface of the petrous bone where Meckel’s cave and the semilunar ganglion sit. 2) GSP groove:Lateral to this impression is a small groove on the anterior, deep surface of the petrous portion of the temporal bone. The groove opens posteriorly into a canal, the hiatus of the facial canal. Grooves for the greater and lesser petrosal nerves: found on the upper surface of the petrous bone. Lateral to itrigeminal impression there are two small grooves, a medial sulcus of the greater petrosal nerve (sulcus n. petrosimajoris) and a lateral sulcus of the lesser petrosal nerve (sulcus n. petrosiminoris). They lead to two openings of the same name, a medial the greater petrosal opening (hiatus canalis n. petrosimajoris) and a lateral the lesser petrosal nerve opening (hiatus canalis n. petrosiminoris). 3) Arcuate eminence (SSC): Above and lateral to the hiatus is a bony prominence, the arcuate eminence, overlying the superior semicircular canal. The arcuate eminence (eminentiaarcuata) is lateral to these openings; it forms due to prominence of the vigorously developing labyrinth, particularly the superior semicircular canal. The internal auditory canal can be identified below the floor of the middle fossa by drilling along a line approximately 60 degrees medial to the arcuate eminence, near the middle portion of the angle between the greater petrosal nerve and arcuate eminence4) Tegmen tympani: A thin lamina of bone, the tegmen tympani, roofs the area above the middle ear and auditory ossicles on the anterolateral side of the arcuate eminence (between the petrosquamous fissure and the arcuate eminence).5) The carotid canal extends upward and medially and provides passage to the internal carotid artery and carotid sympathetic nerves in their course to the cavernous sinus6) Groove for superior petrosal sinus: The superior-most portion of the petrous portion of the temporal bone is a thin ridge, which constitutes part of the posterior border of the middle cranial fossa. This ridge contains the groove for the superior petrosal sinus.
Posterior fossa surface of petrous part of temporal bone blends with mastoid surface of temporal bone. It contains 1) IAM midway between apex and base of petrous. 2) Subarcuatefossafound posterior to EAM and is the site for penetration of subarcuate artery (branch of AICA) which supply SSC.3) vestibular aqueduct: Inferior lateral to EAC is opening for vestibular aqueduct that transmit enodlymphatic duct that communicate endolymphatic sac found between the dural layers and the endolymph of labrynth.4) Cochlear canaliculuswhere cochlear aqueduct (contain perilymph) opens. found at the antromedial edge of jugular foramen just superior and lateral to glossopharyngeal nerve where it enters the jugular foramen. During drilling of posterior lip of IAM care should be given to avoid injury of 1) Common crus of posterior and superior canals which found lateral to the entry of subarcuate artery. 2) Vestibule and Posterior semicircular canal: which are away from EAM by average 7mm 3) Vestibular aqueduct: the endolymphatic duct that marked by the endolymphatic ridge at the level of posterior canal. 4) Inferiorly: the high arched jugular bulb.
The course of the facial nerve can be roughly divided into 5 segments, 1) The pontine segment, between the brainstem and porus, measures 23 to 24 mm in length. At this point the facial nerve is anterior to the cochleovestibular nerve. The special sensory and visceral efferent components of the facial nerve pass in a separate bundle adjacent to the main motor trunk as the nervusintermedius.2) The meatal segment, within the internal auditory canal, is 7 to 8 mm in length. The facial nerve passes superior to the falciform crest in the lateral aspect of the canal and is separated from the superior vestibular nerve by a vertical crest of bone (Bill's bar).3) The labyrinthine segment, between the meatal segment and geniculate ganglion, is 4 mm in length. The osseous canal surrounding the facial nerve is narrowest at the most proximal portion of the labyrinthine segment. This segment passes anterolaterally, paralleling the axis of the arcuate eminence of the superior semicircular canal, and passes superior and in proximity to the basal turn of the cochlea. The geniculate ganglion is triangular and averages 1.09 mm in length. 4) The tympanic or horizontal segment, between the geniculate ganglion and second genu, is 12 to 13 mm in length. The proximal edge of the geniculate ganglion is 5 mm anterosuperior to the posterior edge of the processuscochleariformis. The facial nerve passes superior to the oval window niche, a region where in approximately 55% of cases it is dehisc 5) The mastoid or vertical segment, between the second genu and stylomastoid foramen, measures 15 to 20 mm in length. At the second genu, the semicircular canal lies 0.5 mm posterosuperior to the facial nerve. The digastric ridge is a useful landmark just posterior to the stylomastoid foramen. 6) Extratemporal segment (Stylomastoid foramen to pesanserinus): 15-20mm
Cholesteatoma eroding the horizontal semicircular canal, CT. A: Cholesteatomaopacifies the upper attic and antrum. Note the rounded, smooth margins. There is erosive scalloping of the bone covering the horizontal semicircular canal (arrow). The cholesteatoma has reached the lumen of the canal, causing a fistula. B: Normal right side shows the intact cortex with a normal thickness (arrow).
Glomusjugulare, axial CT. The lesion (white arrow) was visualized through the tympanic membrane. There is demineralization (black arrows) around the jugular foramen. The white cortical line is indistinct and poorly visualized. A small amount of demineralized bone (white arrowhead) on the posterior cortex of the carotid canal indicates tumor. Compare the demineralized bone with the intact cortex and bone on the opposite side.Glomusjugulare, MR T1-weighted image after intravenous contrast. The tumor (T) is visualized in the region of the jugular foramen. Its interface (arrow) with the posterior fossa is clearly defined. The bright signal (arrowhead) in the sigmoid sinus represents slow flow of blood with gadolinium. The margins of the lesion can be clearly seen, though the bony landmarks cannot.
High-resolution CT scan of a longitudinal skull fracture passing approximately parallel to the petrous ridge across the middle fossa floor and squamous portion of the temporal bone. Transverse fracture of the right temporal bone in the axial (A) and coronal (B) planes. Longitudinal fracture of the temporal bone follows the long axis of the petrous apex and crosses the floor of the middle cranial fossa near the foramen spinosum. The usual site of facial nerve injury is its labyrinthine segment. B: Transverse fracture of the temporal bone. The fracture line passes between the foramen magnum posteromedially and the foramen spinosum area anterolaterally and traverses the long axis of the petrous pyramid.
1) Epitympanum2) Middle ear bone articulation3) Body of incus4) Aditus of antrum5) Mastoid antrum6) LSC7) vestibule8) Tympanic segment of facial nerve 9) Pourusacousticus10) Internal auditory canal11) Midlle turn of cochlea 12) Petrous apex13) Head of malleus
Hugh D. Curtin, James D. Rabinov and Peter M. Som(2003): Central Skull Base: Embryology Anatomy, and Pathology in Central skull base in Head and Neck Imaging. Peter M. Som & Hugh D. Curt (edit) Mosby, Inc. St. Louis, Chapter 12 FOURTH EDITION. Volume one 785- 863