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Prepared by:
Shraddha Dahal
Roll no:25
B.Sc. Nursing 4th year
General Objective
At the end of this session, all the B.Sc.
Nursing 3rd year students will be able to
explain about neonatal hyperthermia and
convulsion in newborn.
Specific Objectives
At the end of this session, all the B.Sc. nursing
3rd year students will be able to:
• define neonatal hyperthermia.
• list out the causes of neonatal hyperthermia.
• list out the clinical features of neonatal
hyperthermia.
• list out the consequences of neonatal
hyperthermia.
• describe the management of neonatal
hyperthermia.
• define convulsion in newborn.
• state the incidence of convulsion in
newborn.
• explain the classification of convulsion in
newborn.
• describe the causes of convulsion in
newborn.
• identify the diagnostic measures for
convulsion in newborn .
• describe the management of convulsion in
newborn.
• discuss the prognosis of convulsion in
newborn.
Neonatal Hyperthermia
Neonatal hyperthermia is an alteration in
neonatal thermoregulatory state of neonates
which occurs when the axillary temperature
rises above 37.5°C (WHO, 2003).
Causes
Incubator
Radiant Warmer
Clinical Features
• Baby's axillary temperature is above
37.50C.
• Skin feels hot, flushing and perspiration
occurs.
• Breathing is rapid( >60 breaths / minute).
• Baby's heart rate is rapid (160 beats/
minute).
…contd
• Baby appears dehydrated.
• Lethargic, hypotonia and poor feeding
• Irritability, Weak cry
Sunken Fontanelle
Skin Turgor
Consequences
• Hypotension and dehydration
• Seizures and apnea
• Hypernatremia
Management
• Move the baby away from the source of
heat such as direct sunlight, a fire or an
electric heater.
• Place the baby in a normal temperature
environment(250C-280C).
• If the newborn is in an incubator, the air
temperature should be lowered by 0.50C in
every 15 minutes.
….contd
• If the baby's temperature is more than
400C, undress the baby and sponge the
baby.
• Use lukewarm water for sponge bath.
• Cooling devices are not recommended.
• During the cooling process, the newborn’s
temperature must be monitored every 15-
30 minutes until stable.
….contd
• Give frequent breast feeds or give
expressed milk by cup if the baby doesn't
suck.
• If the newborn cannot breastfeed, extra
fluids should be given intravenously or by
tube at maintainance volume according to
the baby's age.
• If the respiratory rate is more than 60
beats per minute or the baby has chest
indrawing or grunting on expiration , treat
for breathing difficulty.
….contd
• If signs of sepsis appear, treat for sepsis.
• If there are signs of dehydration,correct
dehydration.
• Parental education
CONVULSION IN NEWBORN
• Convulsion in newborn is a paroxysmal
manifestation of neurological dysfunction
caused by abnormal electrical discharges
from the brain resulting in abnormal
involuntary, motor and sensory activities.
• Overall incidence ranges from 2 in 1000 to
14 in 1000 live births.
Classification of Neonatal
Convulsions
Tonic Convulsions
Causes
A. Traumatic causes
• Hypoxic-ischemic encephalopathy
• Intracranial hemorrhage
….contd
B. Metabolic causes
• Hypoglycemia
• Kernicterus
• Hypocalcemia
• Hyponatremia, hypernatremia
• Hypomagnesemia
• Inborn errors of metabolism
….contd
C. Infections
• High fever
• CNS infections
• Tetanus
….contd
D. Other causes
• Cerebral malformations
• Neonatal epileptic syndrome
• Chromosomal syndromes
• Narcotic withdrawal
Schizencephaly
Diagnostic Measures
• History taking
• Laboratory studies
Full blood count
Blood, Urine and CSF cultures
TORCH titer
Blood biochemical estimation
Blood gas analysis
…..contd
• EEG
• Imaging studies
EEG in Newborn
Management
A. To control convulsions
• IV phenobarbitone( most preferred) 20 mg/kg
body weight slowly over a period of 10–15
minutes is effective.
• After 1 hour, if convulsions still persist,
another 20mg/kg body weight IV of
phenobarbitone is given.
• If convulsions still persist, another 10 mg/kg
IV of phenobarbitone can be given .
• A maintenance dose of 2.5–4 mg/kg body
weight per day administered orally or
intramuscularly for at least a period of 2
weeks or even longer.
……contd
• In resistant cases IV phenytoin (Dilantin),
20 mg/kg at the rate of 1 mg/kg/min is
administered. Maintenance dose of 2.5-5
mg/kg/day divided 12 hourly.
• Pyridoxine: IV,100mg/kg/day, TDS for 7
days and the maintainance dose of oral
50-100 mg daily may be effective in
seizures that are refractory to above
medication.
……contd
B. To stabilize vital functions and provide
supportive care :
• The neonate needs special care with
airway clearance, oxygen, IV line, thermal
protection, prevention of aspiration and
injury.
• Infuse normal saline or Ringer lactate 10
ml/kg over 5-10 minutes, if perfusion is
poor. Repeat the same 1-2 times over the
next 30-45 minutes, if perfusion continues
to be poor.
C. To treat the underlying pathology :
• Hypoglycemia : Glucose infusion, 2 ml/kg
of 10% glucose, through an intravenous
line is given over 2–3 minutes. Glucose
infusion is continued at a rate of 4-6
mg/kg/min or 60 ml/kg/day.
……contd
• Hypomagnesemia: Magnesium sulfate (0.4–
0.8 mg/kg) is given IV every 12 hours until
magnesium level is normal.
• Infection: Appropriate antibiotic therapy
• Hypocalcemia: Intravenous administration of
2 ml/kg of 10% calcium gluconate taken
over 10 minutes with strict cardiac
monitoring. This is to be followed by oral
calcium chloride 250 mg with each feed for
few days.
……contd
• To relieve intracranial tension— 10 ml of
20% mannitol is given intravenously over
30–60 minutes.
Prognosis
• It varies with the etiology.
• Hypocalcemic convulsions have an excellent
prognosis whereas convulsions secondary to
congenital malformations have poor outcome.
• The overall mortality rate has decreased but
neurological sequelae are still around 30–
40%.
References
• Subedi, D.,& Gautam ,S.(2017) .Midwifery nursing
part III ( 3rd ed.). Medhavi Publication ,Baneshwor,
Kathmandu,Nepal (pp:175-177).
• Uprety,K. (2017).Essential of child health nursing(1st
ed.).Akshav Publication , kathmandu,Nepal (pp: 83-
85).
• Adhikari,T.(2015). Essentials of Pediatric Nursing (2nd
ed.).Vidhyarthi Pustak Bhandar, Kathmandu, Nepal
(pp:62).
• Dutta,P.(2014).Pediatric Nursing (3rd ed.).Jaypee
Brothers Medical Publisher, New Delhi, India (pp: 83-
85,101-102).
• Koner,H.(Eds.).(2013).DC Dutta's textbook of
obstetrics(8th ed.).Jaypee Brothers Medical
Publishers,New Delhi,India(pp:557-558).
• Paul,V.K & Bagga.A.(2013).Ghai essential
paediatrics(8th ed.).CBS Publishers and
Distributors, New Delhi, India(pp: 552-556, 144).
• Sharma,R. (2013). Essential Paediatrics for
Nurses( 2nd ed.). Jyapee Brothers Medical
Publisher , New Delhi,India( pp:217).
• Thakur, L .(2012).Advanced child health nursing
(3rd ed.).Ultimate Marketing ,Lazimpat
,Kathmandu,Nepal (pp:69 ).
Convulsion and neonatal hyperthermia

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Convulsion and neonatal hyperthermia

  • 1. Prepared by: Shraddha Dahal Roll no:25 B.Sc. Nursing 4th year
  • 2. General Objective At the end of this session, all the B.Sc. Nursing 3rd year students will be able to explain about neonatal hyperthermia and convulsion in newborn.
  • 3. Specific Objectives At the end of this session, all the B.Sc. nursing 3rd year students will be able to: • define neonatal hyperthermia. • list out the causes of neonatal hyperthermia. • list out the clinical features of neonatal hyperthermia. • list out the consequences of neonatal hyperthermia. • describe the management of neonatal hyperthermia.
  • 4. • define convulsion in newborn. • state the incidence of convulsion in newborn. • explain the classification of convulsion in newborn. • describe the causes of convulsion in newborn. • identify the diagnostic measures for convulsion in newborn . • describe the management of convulsion in newborn. • discuss the prognosis of convulsion in newborn.
  • 5. Neonatal Hyperthermia Neonatal hyperthermia is an alteration in neonatal thermoregulatory state of neonates which occurs when the axillary temperature rises above 37.5°C (WHO, 2003).
  • 9. Clinical Features • Baby's axillary temperature is above 37.50C. • Skin feels hot, flushing and perspiration occurs. • Breathing is rapid( >60 breaths / minute). • Baby's heart rate is rapid (160 beats/ minute).
  • 10. …contd • Baby appears dehydrated. • Lethargic, hypotonia and poor feeding • Irritability, Weak cry
  • 11.
  • 14.
  • 15. Consequences • Hypotension and dehydration • Seizures and apnea • Hypernatremia
  • 16. Management • Move the baby away from the source of heat such as direct sunlight, a fire or an electric heater. • Place the baby in a normal temperature environment(250C-280C). • If the newborn is in an incubator, the air temperature should be lowered by 0.50C in every 15 minutes.
  • 17. ….contd • If the baby's temperature is more than 400C, undress the baby and sponge the baby. • Use lukewarm water for sponge bath. • Cooling devices are not recommended. • During the cooling process, the newborn’s temperature must be monitored every 15- 30 minutes until stable.
  • 18. ….contd • Give frequent breast feeds or give expressed milk by cup if the baby doesn't suck. • If the newborn cannot breastfeed, extra fluids should be given intravenously or by tube at maintainance volume according to the baby's age. • If the respiratory rate is more than 60 beats per minute or the baby has chest indrawing or grunting on expiration , treat for breathing difficulty.
  • 19. ….contd • If signs of sepsis appear, treat for sepsis. • If there are signs of dehydration,correct dehydration. • Parental education
  • 20. CONVULSION IN NEWBORN • Convulsion in newborn is a paroxysmal manifestation of neurological dysfunction caused by abnormal electrical discharges from the brain resulting in abnormal involuntary, motor and sensory activities. • Overall incidence ranges from 2 in 1000 to 14 in 1000 live births.
  • 23. Causes A. Traumatic causes • Hypoxic-ischemic encephalopathy • Intracranial hemorrhage
  • 24. ….contd B. Metabolic causes • Hypoglycemia • Kernicterus • Hypocalcemia • Hyponatremia, hypernatremia • Hypomagnesemia • Inborn errors of metabolism
  • 25. ….contd C. Infections • High fever • CNS infections • Tetanus
  • 26. ….contd D. Other causes • Cerebral malformations • Neonatal epileptic syndrome • Chromosomal syndromes • Narcotic withdrawal
  • 28. Diagnostic Measures • History taking • Laboratory studies Full blood count Blood, Urine and CSF cultures TORCH titer Blood biochemical estimation Blood gas analysis
  • 31. Management A. To control convulsions • IV phenobarbitone( most preferred) 20 mg/kg body weight slowly over a period of 10–15 minutes is effective. • After 1 hour, if convulsions still persist, another 20mg/kg body weight IV of phenobarbitone is given. • If convulsions still persist, another 10 mg/kg IV of phenobarbitone can be given . • A maintenance dose of 2.5–4 mg/kg body weight per day administered orally or intramuscularly for at least a period of 2 weeks or even longer.
  • 32. ……contd • In resistant cases IV phenytoin (Dilantin), 20 mg/kg at the rate of 1 mg/kg/min is administered. Maintenance dose of 2.5-5 mg/kg/day divided 12 hourly. • Pyridoxine: IV,100mg/kg/day, TDS for 7 days and the maintainance dose of oral 50-100 mg daily may be effective in seizures that are refractory to above medication.
  • 33. ……contd B. To stabilize vital functions and provide supportive care : • The neonate needs special care with airway clearance, oxygen, IV line, thermal protection, prevention of aspiration and injury. • Infuse normal saline or Ringer lactate 10 ml/kg over 5-10 minutes, if perfusion is poor. Repeat the same 1-2 times over the next 30-45 minutes, if perfusion continues to be poor.
  • 34. C. To treat the underlying pathology : • Hypoglycemia : Glucose infusion, 2 ml/kg of 10% glucose, through an intravenous line is given over 2–3 minutes. Glucose infusion is continued at a rate of 4-6 mg/kg/min or 60 ml/kg/day.
  • 35. ……contd • Hypomagnesemia: Magnesium sulfate (0.4– 0.8 mg/kg) is given IV every 12 hours until magnesium level is normal. • Infection: Appropriate antibiotic therapy • Hypocalcemia: Intravenous administration of 2 ml/kg of 10% calcium gluconate taken over 10 minutes with strict cardiac monitoring. This is to be followed by oral calcium chloride 250 mg with each feed for few days.
  • 36. ……contd • To relieve intracranial tension— 10 ml of 20% mannitol is given intravenously over 30–60 minutes.
  • 37. Prognosis • It varies with the etiology. • Hypocalcemic convulsions have an excellent prognosis whereas convulsions secondary to congenital malformations have poor outcome. • The overall mortality rate has decreased but neurological sequelae are still around 30– 40%.
  • 38.
  • 39. References • Subedi, D.,& Gautam ,S.(2017) .Midwifery nursing part III ( 3rd ed.). Medhavi Publication ,Baneshwor, Kathmandu,Nepal (pp:175-177). • Uprety,K. (2017).Essential of child health nursing(1st ed.).Akshav Publication , kathmandu,Nepal (pp: 83- 85). • Adhikari,T.(2015). Essentials of Pediatric Nursing (2nd ed.).Vidhyarthi Pustak Bhandar, Kathmandu, Nepal (pp:62). • Dutta,P.(2014).Pediatric Nursing (3rd ed.).Jaypee Brothers Medical Publisher, New Delhi, India (pp: 83- 85,101-102).
  • 40. • Koner,H.(Eds.).(2013).DC Dutta's textbook of obstetrics(8th ed.).Jaypee Brothers Medical Publishers,New Delhi,India(pp:557-558). • Paul,V.K & Bagga.A.(2013).Ghai essential paediatrics(8th ed.).CBS Publishers and Distributors, New Delhi, India(pp: 552-556, 144). • Sharma,R. (2013). Essential Paediatrics for Nurses( 2nd ed.). Jyapee Brothers Medical Publisher , New Delhi,India( pp:217). • Thakur, L .(2012).Advanced child health nursing (3rd ed.).Ultimate Marketing ,Lazimpat ,Kathmandu,Nepal (pp:69 ).