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1
Hypothermia
• Significant problem in neonates at birth and
beyond ( 15%)
• Mortality rate twice in hypothermic babies
• Significant morbidity & mortality
• Preventable
• Lack of professional alertness of healthcare
providers
2
■ Situations causing excessive heat loss
■ Poor ability to conserve
■ Poor metabolic heat production
causes of hypothermia
3
■ Situations causing excessive heat loss
cold environment,
■ wet or naked baby,
■ cold linen,
■ during transport, and
■ procedures bath , blood sampling,
infusion
causes of hypothermia
4
■ Poor ability to conserve— LBW, IUGR
■ Poor metabolic heat production-
deficiency of brown fat,
■ CNS damage,
■ hypoxia,
■ hypoglycaemia,
■ sepsis*
causes of hypothermia
5
Why are newborns prone to
develop hypothermia
• Larger surface area per unit body weight
• Limited heat generating mechanisms(Non
shivering thermogenesis)
• vulnerability to getting exposed, being
dependent others
6
factors in LBW/SFD
• Larger surface area than term babies
• Poor insulation (lower subcutaneous fat)
• More permeable skin
• Decreased brown fat
• Poor physiological response to cold
• Early exhaustion of metabolic stores like
glucose
7
heat loss skin-0.3c/min
core-0.1c/min
Thermal balance
Conduction
Radiation
Convection
Evaporation
8
Response to cold
• Muscular activity
• Minimal shivering in term babies
• Metabolic thermogenesis (non shivering
thermogenesis)
9
Non-shivering thermogenesis
• Heat is produced by increasing the metabolism
especially in brown adipose tissue*
• Blood is warmed as it passes through the brown
fat and it in turn warms the body
• Effective thermogenesis require—adequate
brown fat, glucose ,oxygen and intact CNS
pathways
10
Neutral thermal environment
Range of environmental temperature in
which an infant can maintain normal
body temperature with least amount
of BMR and oxygen consumption
normal temperature 36.5-37.3
temperature change not more than 0.3 for skin and
Fall of 2 *C==25% heat generation
11
Temperature recording
• Axillary temperature recording for 3
minutes is recommended for routine
monitoring
• rectal temperature(2min) is unnecessary in
most situations
• human touch( back of the fingers)
12
Diagnosis of hypothermia by
human touch
Feel by touch
Trunk
Feel by touch
Extremities
Interpretation
Warm Warm Normal
Warm Cold Cold stress
Cold Cold Hypothermia
13
Normal range
Cold stress
Moderate hypothermia
Severe hypothermia Outlook grave, skilled
care urgently needed
Danger, warm baby
Cause for concern
37.5o
36.5o
36.0o
32.0o
Axillary temperature in the
newborn (0C)
14
1. Warm delivery room
(>250 C)
2. Warm resuscitation
3. Immediate drying
4. Skin-to-skin contact
5. Breastfeeding
6. Bathing postponed
7. Appropriate clothing
8. Mother & baby
together
9. Professional alert
10. Warm transportation
Prevention of hypothermia: Warm chain
15
Prevention of hypothermia at birth
• Conduct delivery in a warm room( 27.C)
• Dry baby including head immediately with
warm clean towel
• Wrap baby in pre-warmed linen; cover the
head and the limbs
• Place the baby skin to skin on the mother
• Postpone bathing
16
Bathing the baby
Timing of bath
■ Small&/or LBW:
Till the cord falls or
preferably till 2.5 kg
weight
■ Sick /admitted in nursery:
No bath
■ Term baby:
Postpone till next day
Procedure
■ Warm room and warm
water
■ Bathe quickly and gently
■ Dry quickly and
thoroughly
■ Wrap in a warm, dry
towel
■ Dress and wrap infant
■ Use a cap
■ Keep close to mother
17
Bathing the baby
Warm room – warm water Dry quickly & thoroughly
Dress warmly and wrap Give to mother to breast feed
18
Kangaroo Mother care
• Assists in maintaining temperature
• reduces risk of apnea
• reduced risk of infections
• babies cry less and sleeps better(better
neurobehavioral development)
• Facilitates breastfeeding
• Increases duration of breastfeeding
• Improves mother-baby bonding
• better weight gain and early discharge
19
20
The Kangaroo method
21
The Kangaroo method
Place baby in this position Then cover with clothes
22
23
Cot-nursing in hospital
(mother sick)
• Cover adequately in layering*
• adequate feeding( EBF/assisted)
• Keep in thermoneutral environment
• Monitor temperature 3 hourly during initial
postnatal days
24
25
Prevention of hypothermia
(during transport)
• Let temperature stabilize before transport
• Document temperature and take remedial measures
• Carry close to chest,
• if possible in kangaroo position
• Cover adequately, avoid undressing
• Use thermocol box with pre-warmed linen or plastic
sheet or water filled mattress with thermostat
26
Signs and symptoms of
hypothermia
• Peripheral vasoconstriction
- acrocyanosis, cold extremities, mottling
- decreased peripheral perfusion
• CNS depression
- lethargy, poor feeding
bradycardia, seizures
apnea
27
Signs and symptoms (cont..)
• Increased pulmonary artery pressure
- respiratory distress, Cynosis
tachypnea, pulmonary haemorrhage
• Chronic signs
- weight loss, failure to thrive
28
Hypothermia
catecholamines release reduced surfactant production
uncoupling of
beta oxidation
release of FFE
Displaces bilirubin
from albumin
Hyperbillirubinemia
increased BMR
Hypoglycaemia increased o2 requirement
pulmonary and peripheral vasoconstriction
Anaerobic metabolism,
Glycolysis,Hypoxemia,
Metabolic acidosis
CNS and cardiac depression
29
Complications
■ Hypoglycaemia
■ Bleeding ,DIC
■ Acidosis
■ Hypotension
■ Shock
■ Respiratory distress
■ Pulmonary haemorrhage
■ Apnea
■ Cardiac arrest
■ Death
30
Management: Cold stress
(<36.5)
• Cover adequately - remove cold clothes and replace with
warm clothes
• Warm room/bed
• Take measures to reduce heat loss
• Ensure skin-to-skin contact with mother; if not possible,
keep next to mother after fully covering the baby
• Breast feeding*
Monitor axillary temperature every ½ hour till it reaches 36.50 C, then hourly for
next 4 hours, 2 hourly for 12 hours thereafter and 3 hourly as a routine
31
Management: Moderate
hypothermia(32.0°C to 35.9°C )
• Skin to skin contact
• Feeding
• Warm room/ warmer
• Take measures to reduce heat loss
• Provide extra heat
- 200 W bulb
- Heater, warmer, incubator
- Apply warm towels
32
Management: Severe
hypothermia (<320C )
• Provide extra heat preferably under radiant warmer or
air heated incubator
- rapidly warm till 340C, then slow re-warming
• Take measures to reduce heat loss
• Manage T A B C*
• IV fluids: 60-80 ml/kg of 10% Dextrose
• Oxygen
• Inj.vitamin K 1mg in term & 0.5 mg in preterm
• If still hypothermic, consider antibiotics assuming sepsis
Monitor HR, BP, Glucose (if available)
33
Hyperthermia > 37.50C
• Problem in summer months
• May indicate infection in term babies
• Irritable, increased HR & RR
• Flushed face, hot & dry skin
• Apathetic, lethargic and pale
• Stupor, coma, convulsions if temperature > 410C
34
• Place the baby in a normal temperature
environment (25 to 280C), away from any source
of heat
• Undress the baby partially or fully, if necessary
• Give frequent breast feeds
• If temperature > 390C, sponge the baby with tap
water; don’t use cold / ice water for sponge
• Measure the temperature hourly till it becomes
normal
Management of hyperthermia
35
Conclusion
• Prevent hypothermia, maintain “Warm chain”
• Ensure closer monitoring and stricter preventive
measures for LBW and other at risk neonates
• Early detection and prompt remedial measures
are key for reducing this preventable morbidity

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Hypothermia in newborn

  • 1. 1 Hypothermia • Significant problem in neonates at birth and beyond ( 15%) • Mortality rate twice in hypothermic babies • Significant morbidity & mortality • Preventable • Lack of professional alertness of healthcare providers
  • 2. 2 ■ Situations causing excessive heat loss ■ Poor ability to conserve ■ Poor metabolic heat production causes of hypothermia
  • 3. 3 ■ Situations causing excessive heat loss cold environment, ■ wet or naked baby, ■ cold linen, ■ during transport, and ■ procedures bath , blood sampling, infusion causes of hypothermia
  • 4. 4 ■ Poor ability to conserve— LBW, IUGR ■ Poor metabolic heat production- deficiency of brown fat, ■ CNS damage, ■ hypoxia, ■ hypoglycaemia, ■ sepsis* causes of hypothermia
  • 5. 5 Why are newborns prone to develop hypothermia • Larger surface area per unit body weight • Limited heat generating mechanisms(Non shivering thermogenesis) • vulnerability to getting exposed, being dependent others
  • 6. 6 factors in LBW/SFD • Larger surface area than term babies • Poor insulation (lower subcutaneous fat) • More permeable skin • Decreased brown fat • Poor physiological response to cold • Early exhaustion of metabolic stores like glucose
  • 7. 7 heat loss skin-0.3c/min core-0.1c/min Thermal balance Conduction Radiation Convection Evaporation
  • 8. 8 Response to cold • Muscular activity • Minimal shivering in term babies • Metabolic thermogenesis (non shivering thermogenesis)
  • 9. 9 Non-shivering thermogenesis • Heat is produced by increasing the metabolism especially in brown adipose tissue* • Blood is warmed as it passes through the brown fat and it in turn warms the body • Effective thermogenesis require—adequate brown fat, glucose ,oxygen and intact CNS pathways
  • 10. 10 Neutral thermal environment Range of environmental temperature in which an infant can maintain normal body temperature with least amount of BMR and oxygen consumption normal temperature 36.5-37.3 temperature change not more than 0.3 for skin and Fall of 2 *C==25% heat generation
  • 11. 11 Temperature recording • Axillary temperature recording for 3 minutes is recommended for routine monitoring • rectal temperature(2min) is unnecessary in most situations • human touch( back of the fingers)
  • 12. 12 Diagnosis of hypothermia by human touch Feel by touch Trunk Feel by touch Extremities Interpretation Warm Warm Normal Warm Cold Cold stress Cold Cold Hypothermia
  • 13. 13 Normal range Cold stress Moderate hypothermia Severe hypothermia Outlook grave, skilled care urgently needed Danger, warm baby Cause for concern 37.5o 36.5o 36.0o 32.0o Axillary temperature in the newborn (0C)
  • 14. 14 1. Warm delivery room (>250 C) 2. Warm resuscitation 3. Immediate drying 4. Skin-to-skin contact 5. Breastfeeding 6. Bathing postponed 7. Appropriate clothing 8. Mother & baby together 9. Professional alert 10. Warm transportation Prevention of hypothermia: Warm chain
  • 15. 15 Prevention of hypothermia at birth • Conduct delivery in a warm room( 27.C) • Dry baby including head immediately with warm clean towel • Wrap baby in pre-warmed linen; cover the head and the limbs • Place the baby skin to skin on the mother • Postpone bathing
  • 16. 16 Bathing the baby Timing of bath ■ Small&/or LBW: Till the cord falls or preferably till 2.5 kg weight ■ Sick /admitted in nursery: No bath ■ Term baby: Postpone till next day Procedure ■ Warm room and warm water ■ Bathe quickly and gently ■ Dry quickly and thoroughly ■ Wrap in a warm, dry towel ■ Dress and wrap infant ■ Use a cap ■ Keep close to mother
  • 17. 17 Bathing the baby Warm room – warm water Dry quickly & thoroughly Dress warmly and wrap Give to mother to breast feed
  • 18. 18 Kangaroo Mother care • Assists in maintaining temperature • reduces risk of apnea • reduced risk of infections • babies cry less and sleeps better(better neurobehavioral development) • Facilitates breastfeeding • Increases duration of breastfeeding • Improves mother-baby bonding • better weight gain and early discharge
  • 19. 19
  • 21. 21 The Kangaroo method Place baby in this position Then cover with clothes
  • 22. 22
  • 23. 23 Cot-nursing in hospital (mother sick) • Cover adequately in layering* • adequate feeding( EBF/assisted) • Keep in thermoneutral environment • Monitor temperature 3 hourly during initial postnatal days
  • 24. 24
  • 25. 25 Prevention of hypothermia (during transport) • Let temperature stabilize before transport • Document temperature and take remedial measures • Carry close to chest, • if possible in kangaroo position • Cover adequately, avoid undressing • Use thermocol box with pre-warmed linen or plastic sheet or water filled mattress with thermostat
  • 26. 26 Signs and symptoms of hypothermia • Peripheral vasoconstriction - acrocyanosis, cold extremities, mottling - decreased peripheral perfusion • CNS depression - lethargy, poor feeding bradycardia, seizures apnea
  • 27. 27 Signs and symptoms (cont..) • Increased pulmonary artery pressure - respiratory distress, Cynosis tachypnea, pulmonary haemorrhage • Chronic signs - weight loss, failure to thrive
  • 28. 28 Hypothermia catecholamines release reduced surfactant production uncoupling of beta oxidation release of FFE Displaces bilirubin from albumin Hyperbillirubinemia increased BMR Hypoglycaemia increased o2 requirement pulmonary and peripheral vasoconstriction Anaerobic metabolism, Glycolysis,Hypoxemia, Metabolic acidosis CNS and cardiac depression
  • 29. 29 Complications ■ Hypoglycaemia ■ Bleeding ,DIC ■ Acidosis ■ Hypotension ■ Shock ■ Respiratory distress ■ Pulmonary haemorrhage ■ Apnea ■ Cardiac arrest ■ Death
  • 30. 30 Management: Cold stress (<36.5) • Cover adequately - remove cold clothes and replace with warm clothes • Warm room/bed • Take measures to reduce heat loss • Ensure skin-to-skin contact with mother; if not possible, keep next to mother after fully covering the baby • Breast feeding* Monitor axillary temperature every ½ hour till it reaches 36.50 C, then hourly for next 4 hours, 2 hourly for 12 hours thereafter and 3 hourly as a routine
  • 31. 31 Management: Moderate hypothermia(32.0°C to 35.9°C ) • Skin to skin contact • Feeding • Warm room/ warmer • Take measures to reduce heat loss • Provide extra heat - 200 W bulb - Heater, warmer, incubator - Apply warm towels
  • 32. 32 Management: Severe hypothermia (<320C ) • Provide extra heat preferably under radiant warmer or air heated incubator - rapidly warm till 340C, then slow re-warming • Take measures to reduce heat loss • Manage T A B C* • IV fluids: 60-80 ml/kg of 10% Dextrose • Oxygen • Inj.vitamin K 1mg in term & 0.5 mg in preterm • If still hypothermic, consider antibiotics assuming sepsis Monitor HR, BP, Glucose (if available)
  • 33. 33 Hyperthermia > 37.50C • Problem in summer months • May indicate infection in term babies • Irritable, increased HR & RR • Flushed face, hot & dry skin • Apathetic, lethargic and pale • Stupor, coma, convulsions if temperature > 410C
  • 34. 34 • Place the baby in a normal temperature environment (25 to 280C), away from any source of heat • Undress the baby partially or fully, if necessary • Give frequent breast feeds • If temperature > 390C, sponge the baby with tap water; don’t use cold / ice water for sponge • Measure the temperature hourly till it becomes normal Management of hyperthermia
  • 35. 35 Conclusion • Prevent hypothermia, maintain “Warm chain” • Ensure closer monitoring and stricter preventive measures for LBW and other at risk neonates • Early detection and prompt remedial measures are key for reducing this preventable morbidity