This document presents a case study of Sripatum University's (SPU) approach to online education, called SMILE. SPU is a top private university in Thailand with three campuses and over 20,000 students. The SMILE approach focuses on enabling e-learning, being outcome-based, using interactive classrooms, having motivated educators, and directing self-learning students. Key aspects of SPU's online education ecology are discussed, including its learning management system, interactive e-books, and social media integration. The document also highlights case studies of educators who have successfully implemented blended learning models at SPU through strategies like active learning approaches and frequent quizzing.