Circadian rhythms also known as "The Body Clock" is the physical, mental and behavioral changes that follow roughly 24 hrs. cycle responding to light and darkness in the organism.

1. Circadian rhythms
&
Human health
Presented by
Dr. Sudhakar Kokate
Director PPRC, India

2. Circadian rhythms .…
 Also known as the “Body clock”
 Physical, mental and behavioural changes that
follow a roughly 24 hrs. cycle responding to light
and darkness in the organism
 Found in living things, plants, animals and even
among tiny microbes
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3. Circadian rhythms .…
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4. Circadian rhythms ….
 Related to biological cycle
 Study of Circadian rhythms and health is known
as “Chronobiology”
 Biological cycle controls Circadian rhythms –
governing of interacting molecules in cells
throughout the body
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5. Master clock ….
 Master clock: Brain
 A group of nerve cells ‘Suprachiasmatic nucleus’
(SCN) containing 20,000 nerve cells are located
in hypothalamus
 Location: above optic nerves from eyes cross
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6. Brain
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7. Suprachiasmatic nucleus
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8. About CR ….
 Circadian rhythms influence sleep wake cycles,
hormone release and other bodily functions
 CR – linked to sleep disorders e.g. Insomnia,
Obesity, Diabetes, Depression, Bipolar disorders
and Seasonal Affective Disorder (SAD)
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9. Insomnia
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10. Obesity
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11. Diabetes
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12. Depression
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13. Bipolar disorders
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14. Seasonal Affective Disorder (SAD)
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15. About CR ….
 CR tells our body when to sleep and regulate
many other physiological processes
 This internal body clock is affected by
environmental cues like sunlight and
temperature
 When CR is disrupted, sleeping & eating
patterns can run amok
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16. Physiological disruption leads to ….
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17. Research ….
 A growing body of research is examining the
adverse health effects like increasing cardio-
vascular events, observing neurological problems
like depression and bipolar disorders.
 It also affects immune and metabolic systems
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18. Immune system
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19. Metabolic system
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20. Research ….
 Scientists are looking into:
1. How brain-neuro system works in disorder?
2. What are effective remedies without side effects
with minimum duration of time span?
3. Behaviour of Human being in disrupted CR
position
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21. Research ….
4. Treatment of sleep disorders, Jet lag and other
health related issues
5. Do Ayurvedic plants control Circadian rhythms
in plants, animals and microbes? If so how and
at what level of output?
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22. Research ….
6. Are there any natural control for strengthening
nerves and muscle? If so how and what
mechanism does it possess?
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23. Remedies ….
 Change or modify lifestyle
 Ideal diet plan – implementation
 Yoga, exercises and meditation
 Use of herbal technology
 Well disciplinary actions in exact time
 Strengthen and calm – nerves and muscles
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24. Yoga
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25. Exercise
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26. Meditation
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27. Cryobiology
 Study of cell preservation technology with low
temperature
 Applied science
 Rule: Every 10°C reduction in temperature
= 50 % decrease in oxygen consumption
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28. Cryobiology
 Temperature ranges 32 to 37°C
and -80 to -196°C
 Many Journals, Societies study Cryobiology
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29. Neurochemicals ….
Organic molecules participating in Neural activity
 Neuropeptide: Oxytocin signifies maternal
behaviour, stress wound healing
 Glutamate
 GABA: Inhibits neurotransmission
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30. Neurochemicals
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31. Neuropeptide
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32. Oxytocin
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33. Glutamate
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34. GABA
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35. Neurochemicals ….
Organic molecules participating in Neural activity
 Dopamine: Function of the limbic system,
emotional function and control
 Serotonin: Mood, sleep and alertness, sensation
of pleasure
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36. Dopamine
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37. Serotonin
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38. Neurochemicals ….
Organic molecules participating in Neural activity
 Acetylcholine: Memory
 Nitric oxide
 Endocannabinoids: Eicosanoids
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39. Acetylcholine
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40. Nitric oxide
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41. Endocannabinoids
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42. Foods for healthy nerves ….
₪ Milk
₪ Yogurt
₪ Honey
₪ Apple
₪ Mangoes
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₪ Potatoes
₪ Bananas
₪ Herbal tea
₪ Whole grain
₪ Sweet potatoes

43. Foods for healthy nerves ….
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44. Foods for healthy nerves ….
₪ Pineapples
₪ Beet salad
₪ Grape fruits
₪ Oranges
₪ Almonds
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₪ Green salad
₪ Dates
₪ Cashew nuts
₪ Coconut water

45. PPRC/INDIA 44

46. ₪ Tulsi
₪ Sunflower
₪ Papaya
₪ Peppermint
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₪ Avocado
₪ Cabbage
₪ Cauliflower
₪ Asparagus

47. Tulsi (Ocimum sanctum)
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48. Sunflower
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49. Papaya
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50. Peppermint
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51. Avocado
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52. Cabbage
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53. Cauliflower
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54. Asparagus
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55. ₪ Alfalfa
₪ Parsley
₪ Garlic
₪ Beet
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₪ Kale
₪ Hemp
₪ Fenugreek
₪ Lime

56. Alfalfa
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57. Parsley
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58. Garlic
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59. Beet
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60. Kale
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61. Hemp
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62. Fenugreek
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63. Lime
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64. Thank You !!
“BE WITH US”